Gene

KWMTBOMO01918  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006209

Annotation

transport_protein_Sec61_beta_subunit_[Bombyx_mori]

Location

Bomo_Chr4(+):8058844-8060125      View in EpiBrowser

Full name

Protein transport protein Sec61 subunit beta       + More
DNA ligase      

Location in the cell

Nuclear   Reliability : 3.505

CDS

ATGCCTCAATCTCCGAGTGCTACCTCTGTAGGATCTGGGAGTAGATCACCCACAAAAGCTTCTGCTGGCCCACGAACAGCCAGTGGTAGTACAGTCCGTCAACGAAAATCAACTACTACTACAACTGCAGCCAGAAACCGAAGCACTGGTGCTGGTTCTGGAGGAATGTGGAGGTTCTATACCGATGATTCTCCTGGAGTCAAAGTGGGGCCAGTTCCTGTTTTAGTGATGTCTCTCCTGTTTATTGCATCGGTATTCATGTTACACATTTGGGGAAAATATACTAGAGCATAA

Protein

MPQSPSATSVGSGSRSPTKASAGPRTASGSTVRQRKSTTTTTAARNRSTGAGSGGMWRFYTDDSPGVKVGPVPVLVMSLLFIASVFMLHIWGKYTRA

Description

Necessary for protein translocation in the endoplasmic reticulum.

Catalytic Activity

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.

Similarity

Belongs to the SEC61-beta family.
Belongs to the ATP-dependent DNA ligase family.
Belongs to the ubiquitin-activating E1 family.

Uniprot

Q2F5L5   A0A3G1T1M4   A0A0L7LLW4   I4DM80   I4DIW6   A0A2W1BUV0   + More
A0A2J7Q7L7   S4PSG1   A0A2A4K2S8   A0A1B0GP49   A0A2H1VHW2   A0A212ETV8   A0A194RC58   A0A1B0CN43   R4V3X5   A0A1L8DTQ0   A0A067RC56   A0A224Y3A0   G3CJT4   A6YPG7   R4G497   A0A182P3S4   A0A1Y9HDT6   A0A182MWE5   A0A2M4A4Y3   R4WCV8   A0A2M3Z603   A0A2M4A504   A0A2M4C4Y1   W5JB51   A0A182FU09   A0A1I8JVE6   A0A182XC58   Q7PN12   T1E707   A0A1Q3G3H2   A0A0N7Z990   A0A182WF99   Q1HR43   Q5MIQ6   E0VEK0   A0A154PPG8   T1E3D0   A0A182YJY9   A0A2R7WL65   A0A084VSB2   A0A182MY31   T1IE84   E2B1V5   A0A182UJ46   B0WPQ9   A0A026WJZ4   A0A182G843   L7M5V1   A0A131XEU4   K7JBG6   A0A1W4X3J9   A0A195F9S6   A0A0K8TPU9   A0A0P0CW26   A0A195BYH6   A0A0B8RQ84   Q8UW24   V8NY33   A0A1W7RDK6   T1E4Y2   J3S9I4   F4WFG2   A0A158NCW1   G3MPP0   A0A224Z8H4   A0A131YEU4   A0A091G9I6   A0A1E1XM89   A0A195CR29   A0A151X624   U3FB92   A0A091I3F3   R7VQG6   A0A087QWZ6   E9IMA7   A0A093GTB3   H0ZEX2   A0A2I0MVU6   A0A2I0US50   A0A3L8T107   A0A218VB69   A0A1V4J895   A0A0Q3TND0   B5FZ77   B4LNA4   B4KMZ6   B4J786   A0A0A0AIR8   D6WLZ4   G1N714   G1KIE1   A0A091VN26   A0A091QX39   F1NWX7  

EC Number

6.5.1.1

Pubmed

19121390    26227816    22651552    28756777    23622113    22118469    + More
26354079    24845553    21058630    18207082    23691247    20920257    23761445    12364791    14747013    17210077    27129103    17204158    17510324    17244540    24945155    20566863    24330624    25244985    24438588    20798317    24508170    26483478    25576852    28049606    20075255    26369729    26445494    25476704    24297900    26358130    23758969    23025625    21719571    21347285    22216098    28797301    26830274    29209593    23915248    23371554    21282665    20360741    30282656    17018643    17994087    18362917    19820115    20838655    15592404   

EMBL

BABH01005049    DQ311408    DQ631893    ABD36352.1    ABF85698.1    MG992459    + More
AXY94897.1    JTDY01000698    KOB76176.1    AK402398    BAM19020.1    AK401234    BAM17856.1    KZ149895    PZC78828.1    NEVH01017441    PNF24578.1    GAIX01013848    JAA78712.1    NWSH01000193    PCG78561.1    AJVK01014962    ODYU01002642    SOQ40413.1    AGBW02012530    OWR44926.1    KQ460398    KPJ15187.1    AJWK01019780    KC740694    AGM32518.1    GFDF01004242    JAV09842.1    KK852561    KDR21342.1    GFTR01001445    JAW14981.1    HP639851    AEM97988.1    EF638978    GEMB01003747    ABR27863.1    JAR99473.1    ACPB03007951    GAHY01000951    JAA76559.1    AXCM01000326    GGFK01002490    MBW35811.1    AK417208    BAN20423.1    GGFM01003198    MBW23949.1    GGFK01002481    MBW35802.1    GGFJ01011060    MBW60201.1    ADMH02001745    ETN61226.1    AAAB01008966    EAA12929.5    GAMD01003442    JAA98148.1    GFDL01000693    JAV34352.1    GDKW01001211    JAI55384.1    DQ440251    CH478160    ABF18284.1    EAT33737.1    AY826154    GAPW01006468    AAV90726.1    JAC07130.1    DS235093    EEB11806.1    KQ434998    KZC13334.1    GALA01000470    JAA94382.1    KK854844    PTY19175.1    ATLV01015907    KE525041    KFB40856.1    ACPB03029634    GL444981    EFN60311.1    DS232028    EDS32468.1    KK107167    EZA56372.1    JXUM01151434    KQ571216    KXJ68221.1    GACK01006555    JAA58479.1    GEFH01004435    JAP64146.1    AAZX01002870    KQ981727    KYN36967.1    GDAI01001452    JAI16151.1    KP777785    ALJ10927.1    KQ976396    KYM92991.1    GBSH01002451    JAG66575.1    AF159543    AAL54898.1    AZIM01001552    ETE66472.1    GDAY02002208    JAV49224.1    GAAZ01002246    JAA95697.1    JU175844    GBEX01003062    AFJ51368.1    JAI11498.1    GL888115    EGI67213.1    ADTU01011954    JO843841    AEO35458.1    GFPF01011606    MAA22752.1    GEDV01010664    JAP77893.1    KL447915    KFO78623.1    GFAA01003066    JAU00369.1    KQ977408    KYN02947.1    KQ982490    KYQ55792.1    GAEP01001457    GBEW01000926    JAB53364.1    JAI09439.1    KL218152    KFP02747.1    KB375692    EMC82578.1    KL225961    KFM05750.1    GL764129    EFZ18374.1    KL217005    KFV72616.1    ABQF01031308    ABQF01031309    ABQF01031310    AKCR02000001    PKK33803.1    KZ505645    PKU48869.1    QUSF01000001    RLW13175.1    MUZQ01000018    OWK62971.1    LSYS01008581    OPJ68451.1    LMAW01002080    KQK81998.1    DQ214346    DQ214347    DQ214348    ACH44338.1    CH940648    EDW61056.1    CH933808    EDW09918.2    CH916367    EDW02104.1    KL871944    KGL94031.1    KQ971343    EFA03379.1    KL411190    KFR04070.1    KK805031    KFQ31489.1    AADN05000026   

Proteomes

UP000005204    UP000037510    UP000235965    UP000218220    UP000092462    UP000007151    + More
UP000053240    UP000092461    UP000027135    UP000015103    UP000075885    UP000075900    UP000075883    UP000000673    UP000069272    UP000075903    UP000076407    UP000007062    UP000075920    UP000008820    UP000009046    UP000076502    UP000076408    UP000030765    UP000075884    UP000000311    UP000075902    UP000002320    UP000053097    UP000069940    UP000249989    UP000002358    UP000192223    UP000078541    UP000078540    UP000007755    UP000005205    UP000053760    UP000078542    UP000075809    UP000054308    UP000053286    UP000053875    UP000007754    UP000053872    UP000276834    UP000197619    UP000190648    UP000051836    UP000008792    UP000009192    UP000001070    UP000053858    UP000007266    UP000001645    UP000001646    UP000053283    UP000000539   

PRIDE

Q2F5L5   

Pfam

PF03911   Sec61_beta        + More
PF03372   Exo_endo_phos
PF16190   E1_FCCH
PF10585   UBA_e1_thiolCys
PF01068   DNA_ligase_A_M
PF09358   E1_UFD
PF00899   ThiF
PF16191   E1_4HB
PF04679   DNA_ligase_A_C
PF04675   DNA_ligase_A_N

Interpro

IPR030671   Sec61-beta/Sbh        + More
IPR016482   SecG/Sec61-beta/Sbh       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR042302   E1_FCCH_sf       
IPR033127   UBQ-activ_enz_E1_Cys_AS       
IPR032418   E1_FCCH       
IPR042063   Ubi_acti_E1_SCCH       
IPR018074   UBQ-activ_enz_E1_CS       
IPR016059   DNA_ligase_ATP-dep_CS       
IPR012340   NA-bd_OB-fold       
IPR032420   E1_4HB       
IPR012310   DNA_ligase_ATP-dep_cent       
IPR035985   Ubiquitin-activating_enz       
IPR018075   UBQ-activ_enz_E1       
IPR000594   ThiF_NAD_FAD-bd       
IPR038252   UBA_E1_C_sf       
IPR000977   DNA_ligase_ATP-dep       
IPR000011   UBQ/SUMO-activ_enz_E1-like       
IPR018965   Ub-activating_enz_E1_C       
IPR019572   UBA_E1_Cys       
IPR012308   DNA_ligase_ATP-dep_N       
IPR036599   DNA_ligase_N_sf       
IPR012309   DNA_ligase_ATP-dep_C       

SUPFAM

SSF56219   SSF56219        + More
SSF69572   SSF69572       
SSF117018   SSF117018       
SSF50249   SSF50249       

Gene 3D

3.60.10.10     1.10.10.2660     1.10.3260.10     2.40.30.180     3.10.290.60    

ProteinModelPortal

Q2F5L5   A0A3G1T1M4   A0A0L7LLW4   I4DM80   I4DIW6   A0A2W1BUV0   + More
A0A2J7Q7L7   S4PSG1   A0A2A4K2S8   A0A1B0GP49   A0A2H1VHW2   A0A212ETV8   A0A194RC58   A0A1B0CN43   R4V3X5   A0A1L8DTQ0   A0A067RC56   A0A224Y3A0   G3CJT4   A6YPG7   R4G497   A0A182P3S4   A0A1Y9HDT6   A0A182MWE5   A0A2M4A4Y3   R4WCV8   A0A2M3Z603   A0A2M4A504   A0A2M4C4Y1   W5JB51   A0A182FU09   A0A1I8JVE6   A0A182XC58   Q7PN12   T1E707   A0A1Q3G3H2   A0A0N7Z990   A0A182WF99   Q1HR43   Q5MIQ6   E0VEK0   A0A154PPG8   T1E3D0   A0A182YJY9   A0A2R7WL65   A0A084VSB2   A0A182MY31   T1IE84   E2B1V5   A0A182UJ46   B0WPQ9   A0A026WJZ4   A0A182G843   L7M5V1   A0A131XEU4   K7JBG6   A0A1W4X3J9   A0A195F9S6   A0A0K8TPU9   A0A0P0CW26   A0A195BYH6   A0A0B8RQ84   Q8UW24   V8NY33   A0A1W7RDK6   T1E4Y2   J3S9I4   F4WFG2   A0A158NCW1   G3MPP0   A0A224Z8H4   A0A131YEU4   A0A091G9I6   A0A1E1XM89   A0A195CR29   A0A151X624   U3FB92   A0A091I3F3   R7VQG6   A0A087QWZ6   E9IMA7   A0A093GTB3   H0ZEX2   A0A2I0MVU6   A0A2I0US50   A0A3L8T107   A0A218VB69   A0A1V4J895   A0A0Q3TND0   B5FZ77   B4LNA4   B4KMZ6   B4J786   A0A0A0AIR8   D6WLZ4   G1N714   G1KIE1   A0A091VN26   A0A091QX39   F1NWX7  

PDB

4CG6     E-value=4.7298e-11,     Score=156

KEGG

733070    K09481 protein transport protein SEC61 subunit beta | (RefSeq) transport protein Sec61 beta subunit

PATHWAY

03060    Protein export - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)

GO

GO:0006886   GO:0016021   GO:0005784   GO:0006616   GO:0005086   GO:0031205   GO:0031204   GO:0003677   GO:0006260   GO:0071897   GO:0006464   GO:0008641   GO:0006310   GO:0051103   GO:0005524   GO:0003910   GO:0030970   GO:0030433   GO:0048408   GO:0015031   GO:0010507   GO:0005634   GO:0006397   GO:0003676   GO:0043401   GO:0003707   GO:0004651  

PANTHER

PTHR13509  

Length:

97

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.51626

Exp number, first 60 AAs:

0.06918

Total prob of N-in:

0.03316

outside

1  -  68

TMhelix

69  -  91

inside

92  -  97

 

 

Pi

43.12894

Theta

127.960077

Tajima's D

-2.106814

CLR

800.424303

CSRT

0.00909954502274886

Interpretation

Uncertain