Gene

KWMTBOMO01888

Pre Gene Modal

BGIBMGA006197

Annotation

PREDICTED:_U2_small_nuclear_ribonucleoprotein_auxiliary_factor_35_kDa_subunit-related_protein_2_[Plutella_xylostella]

Location

Bomo_Chr4(+):7395169-7399303      View in EpiBrowser

Full name

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1      

Alternative Name

CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1
SP2
U2(RNU2) small nuclear RNA auxiliary factor 1-like 1

Location in the cell

Nuclear   Reliability : 3.273

CDS

ATGGGAAGGCATTCAGAGTGGAGGAGAATTGCAAAGCGTCAAAGAAGACGTAAAATAAGAGTACAACAAGCCCAATTAAGAGACTCAATTCTGGAGGATTCTGATTTACAAGCACAGCAACAAATATTAGATAACCTAATAGAAGAACAAATAATTTTATCAAATAAGATTGAGAACGAGAAATGGTTACAAGCAGAAAAAAATTACATGGATAATTGGGAAAAACTTCAGCAATATAAAGAAAGATTGTTGCAGGAAAAAATGGAACAAAAAATCAAATTAACACTTGAATGGGAAGCAGAAAAAGAGAGACGAAAAATAGAAGAAGAAAAATTAAAACAAATTAAAGAAGAAAATATGAAGAAACATCAAGAATTTCTGGAGAATTTACAAAATTTTATGGCGGGTGATTCGTGTGAACCTCCTAAAGAGTTGAATTATGTGTGTGATACGCGTCCTGGCGCCGAGATGTGCACATTTTTTTCTAAAACTGCGACATGTCGGTTTGGGGACCAGTGTTCAAGAAATCATCAATATCCAAGTATAAGCAACGTTTTGTTGGCCAAAAATTTTTACGCTCATTTCGGTCTCGACAATATGTTTGAAAATAATGAATATGACGCTGATATTATGTTAGAATATGATGAAAATGAAACTTACAAGGAATTTGAAGAATTCTTCTGTGATGTTTTGACAGAATTCGAAAAATTTGGAAAAATAGTGCAATTTAAGGTTTGTAAAAATTACGAAAAACATCTTCGTGGTAATACGTACATAGAATATGCAGATTTACGATGTGCGGTGGCTGCATATAGGTTTCTGAATTCACGATGGTACGGCGGTAGGCAACTCTCCTTACAGTTCTGCAATATTCGTTCATGGAGAAATGCTATATGCGGCCTCCAGGCGAAACAGCGATGTCATAAAGGCCGCTCATGTAACTTCTTACACATATTCAGAAATCCCAATAACTTATTTTCTTTACAAAAATTACCTGAAGAAAACTATATTCCTAGAAGACGAACTCCGCCCCGTTCATGGAGGTGGTCAGAATCCCCAGAAACTGAAATACCGAAACGCACCAAATCTTCGAGAGAAGCAAACGATGAAGAAAAAAAGAATAGAGAAAGACGTCGAAGTCATAAAAGAAAACTCAGAAAAGACTAA

Protein

MGRHSEWRRIAKRQRRRKIRVQQAQLRDSILEDSDLQAQQQILDNLIEEQIILSNKIENEKWLQAEKNYMDNWEKLQQYKERLLQEKMEQKIKLTLEWEAEKERRKIEEEKLKQIKEENMKKHQEFLENLQNFMAGDSCEPPKELNYVCDTRPGAEMCTFFSKTATCRFGDQCSRNHQYPSISNVLLAKNFYAHFGLDNMFENNEYDADIMLEYDENETYKEFEEFFCDVLTEFEKFGKIVQFKVCKNYEKHLRGNTYIEYADLRCAVAAYRFLNSRWYGGRQLSLQFCNIRSWRNAICGLQAKQRCHKGRSCNFLHIFRNPNNLFSLQKLPEENYIPRRRTPPRSWRWSESPETEIPKRTKSSREANDEEKKNRERRRSHKRKLRKD

Description

Plays a role in splicing of the U12-type introns (PubMed:29617656). Implicated also in removal of U2 introns positioned adjacent to a U12 intron (PubMed:29617656).

Subunit

Interacts with SF3B1 (PubMed:29617656). Interacts with ZCRB1 (PubMed:29617656).

Miscellaneous

Maternally imprinted. Active paternal allele is unmethylated whereas the inactive maternal allele is highly methylated.

Keywords

Complete proteome   Metal-binding   mRNA processing   mRNA splicing   Nucleus   Phosphoprotein   Reference proteome   Repeat   Ribonucleoprotein   RNA-binding   Spliceosome   Zinc   Zinc-finger  

Feature

chain  U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1

Uniprot

H9J9K4   A0A2A4J648   A0A1E1W738   A0A194R1V1   A0A194PKN7   A0A2H1W8S4   + More
A0A212F0U2   A0A2W1BUU4   A0A0L7LH51   A0A2J7R7K6   A0A067RL47   A0A1B6JJ05   A0A1B6FEK0   A0A1B6LDW3   A0A0A9VXS1   A0A146L3S3   A0A0K8SSU4   A0A0A9W0P2   A0A146LQA1   A0A2A3ETV9   A0A088A3L1   A0A2H8TH77   A0A3Q0IYM6   A0A026WTD8   Q793C9   Q64707   G1MH80   Q5RK33   Q8BST8  

Pubmed

19121390    26354079    22118469    28756777    26227816    24845553    + More
25401762    26823975    24508170    30249741    11463825    12040188    15489334    14673161    21183079    8284201    8136831    7870588    10679248    29617656    20010809    15057822    10349636    11042159    11076861    11217851    12466851    16141073   

EMBL

BABH01004996    NWSH01002982    PCG67148.1    GDQN01008256    JAT82798.1    KQ460870    + More
KPJ11763.1    KQ459601    KPI93892.1    ODYU01007034    SOQ49423.1    AGBW02011047    OWR47321.1    KZ149895    PZC78852.1    JTDY01001163    KOB74689.1    NEVH01006731    PNF36817.1    KK852561    KDR21330.1    GECU01008597    JAS99109.1    GECZ01021127    JAS48642.1    GEBQ01018112    JAT21865.1    GBHO01042617    JAG00987.1    GDHC01016673    JAQ01956.1    GBRD01009929    JAG55895.1    GBHO01042618    JAG00986.1    GDHC01008601    JAQ10028.1    KZ288187    PBC34712.1    GFXV01001575    MBW13380.1    KK107111    QOIP01000011    EZA58931.1    RLU16945.1    AF309654    BC132555    BC138594    AB089806    CH466595    AAG47771.1    AAI32556.1    AAI38595.1    BAC07536.1    EDL07875.1    D17407    S69507    D26474    ACTA01139050    AC109547    BC086322    AAH86322.1    AK030552    BAC27017.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000235965    UP000027135    UP000242457    UP000005203    UP000079169    UP000053097    UP000279307    UP000000589    UP000008912    UP000002494   

PRIDE

H9J9K4    Q64707   

Pfam

PF00076   RRM_1        + More
PF00642   zf-CCCH
PF15813   DUF4708

Interpro

IPR035979   RBD_domain_sf        + More
IPR009145   U2AF_small       
IPR003954   RRM_dom_euk       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR000571   Znf_CCCH       
IPR031643   DUF4708       
IPR036855   Znf_CCCH_sf       

SUPFAM

SSF54928   SSF54928        + More
SSF90229   SSF90229       

Gene 3D

3.30.70.330    

ProteinModelPortal

H9J9K4   A0A2A4J648   A0A1E1W738   A0A194R1V1   A0A194PKN7   A0A2H1W8S4   + More
A0A212F0U2   A0A2W1BUU4   A0A0L7LH51   A0A2J7R7K6   A0A067RL47   A0A1B6JJ05   A0A1B6FEK0   A0A1B6LDW3   A0A0A9VXS1   A0A146L3S3   A0A0K8SSU4   A0A0A9W0P2   A0A146LQA1   A0A2A3ETV9   A0A088A3L1   A0A2H8TH77   A0A3Q0IYM6   A0A026WTD8   Q793C9   Q64707   G1MH80   Q5RK33   Q8BST8  

PDB

4YH8     E-value=6.24494e-20,     Score=240

KEGG

101743842    no KO assigned | (RefSeq) U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related

GO

GO:0003723   GO:0089701   GO:0000398   GO:0046872   GO:0030628   GO:0005681   GO:0005689   GO:0000245   GO:0000166   GO:0003676   GO:0043401   GO:0003677   GO:0003707   GO:0004651   GO:0005634  

PANTHER

PTHR12620  

Subcellular location

Nucleus  

Length:

388

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00216

Exp number, first 60 AAs:

0

Total prob of N-in:

0.07116

outside

1  -  388

 

 

Pi

247.520208

Theta

163.023011

Tajima's D

1.669654

CLR

0.143751

CSRT

0.821458927053647

Interpretation

Uncertain