Gene

KWMTBOMO01879

Pre Gene Modal

BGIBMGA006192

Annotation

PREDICTED:_protein_Dr1_[Amyelois_transitella]

Location

Bomo_Chr4(+):7295999-7298239      View in EpiBrowser

Full name

Protein Dr1      

Alternative Name

Down-regulator of transcription 1
Negative cofactor 2-beta
dNC2

Location in the cell

Nuclear   Reliability : 3.963

CDS

ATGGGAAGTCCAGAGCGTGAACTTTGTCCACCACCTTCAGAAGAGGACGAACTGACTCTACCAAGAGCTAGTATAAATAAAATGATAAAAGAGTTAGTGCCTTCTGTTCGTGTAGCGTTCGAGTCAAGGGAGTTAATCCTAAATTGCTGCACTGAATTCATACATTTGATTAGTTCTGAAGCCAATGAAGTATGTAATCAAAGCAATAAGAAAACAATTAATGCAGAACATGTCCTTACAGCCCTAGACAGATTAGGATTTAGTGACTACACAATAGAAGCAGAAGCTGTCTTAAAAGATTGTAAAGCAGTGGCGGCTAAAAGAAGACGACAAAGCACACGCCTTGAGAATTTAGGCATTCCAGAAGAAGAATTATTGAGACAACAACAAGAACTGTTTGCAAAGGCCCGTGAGGAACAAGCAAAACAAGAACAGCAACAGTGGCTTTTACTACAACAACAAGGACTTGTTGGTGTTGAAGGAAATGCACAACCATATGTACCACCTACAACTGCTCCAAGAACTGATGATGATGAAGATGATGATTACTCATAA

Protein

MGSPERELCPPPSEEDELTLPRASINKMIKELVPSVRVAFESRELILNCCTEFIHLISSEANEVCNQSNKKTINAEHVLTALDRLGFSDYTIEAEAVLKDCKAVAAKRRRQSTRLENLGIPEEELLRQQQELFAKAREEQAKQEQQQWLLLQQQGLVGVEGNAQPYVPPTTAPRTDDDEDDDYS

Description

Bifunctional basic transcription factor. Activates transcription of DPE (Downstream Promoter Element) containing promoters while repressing transcription of promoters which contain TATA elements.

Subunit

Interacts with NC2-alpha/Drap1 to form the dNC2 complex.

Similarity

Belongs to the NC2 beta/DR1 family.

Keywords

Activator   Complete proteome   Direct protein sequencing   DNA-binding   Nucleus   Reference proteome   Repressor   Transcription   Transcription regulation  

Feature

chain  Protein Dr1

Uniprot

H9J9J9   S4PH31   A0A194R2K6   A0A212F0S4   A0A2H1WCZ5   A0A1E1WIC4   + More
A0A2W1BM42   A0A2A4JFE6   A0A194PLN0   A0A1A9VLY2   A0A1B0AUG4   A0A1B0AFH5   A0A1A9X5H4   D3TLC0   A0A1I8PGM1   A0A1I8NH17   W8BAG3   A0A0L0C1S7   Q16XU3   A0A1Q3FD22   B0WQA9   A0A034V096   A0A0K8TZ04   A0A336M126   A0A023EIT3   B4KLC5   B4LRY7   A0A0K8TR38   B4MZ75   A0A1W4W022   B4HXL1   B4Q5Y6   Q9VJQ5   B4P0X1   Q29P65   B4GK73   A0A0M4EGB6   A0A3B0K741   B3N5M7   B3MLD1   A0A0A1XCD1   U5EXT9  

Pubmed

19121390    23622113    26354079    22118469    28756777    20353571    + More
25315136    24495485    26108605    17510324    25348373    24945155    26483478    17994087    26369729    22936249    11062130    10471707    10731132    12537572    12537569    16120803    17550304    15632085    18057021    25830018   

EMBL

BABH01004984    GAIX01005945    JAA86615.1    KQ460870    KPJ11754.1    AGBW02011047    + More
OWR47330.1    ODYU01007836    SOQ50955.1    GDQN01004310    JAT86744.1    KZ150033    PZC74684.1    NWSH01001584    PCG70787.1    KQ459601    KPI93903.1    JXJN01003625    CCAG010009218    EZ422222    ADD18498.1    GAMC01010883    JAB95672.1    JRES01001003    KNC26202.1    CH477532    EAT39450.1    GFDL01009569    JAV25476.1    DS232037    EDS32772.1    GAKP01023391    JAC35567.1    GDHF01032798    JAI19516.1    UFQT01000094    UFQT01000876    SSX19668.1    SSX27773.1    JXUM01142785    GAPW01005045    GAPW01005044    KQ569477    JAC08554.1    KXJ68613.1    CH933807    EDW11786.1    CH940649    EDW63663.2    GDAI01000759    JAI16844.1    CH963913    EDW77471.1    CH480818    EDW51791.1    CM000361    CM002910    EDX05089.1    KMY90312.1    AF302257    AE014134    AY060717    DQ138728    CM000157    EDW89045.1    CH379058    EAL34428.1    CH479184    EDW37039.1    CP012523    ALC39705.1    OUUW01000046    SPP90017.1    CH954177    EDV57986.1    CH902620    EDV30720.1    KPU73002.1    GBXI01006174    JAD08118.1    GANO01000757    JAB59114.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000218220    UP000053268    UP000078200    + More
UP000092460    UP000092445    UP000091820    UP000092444    UP000095300    UP000095301    UP000037069    UP000008820    UP000002320    UP000069940    UP000249989    UP000009192    UP000008792    UP000007798    UP000192221    UP000001292    UP000000304    UP000000803    UP000002282    UP000001819    UP000008744    UP000092553    UP000268350    UP000008711    UP000007801   

PRIDE

H9J9J9    Q9VJQ5   

Pfam

PF00808   CBFD_NFYB_HMF

Interpro

IPR003958   CBFA_NFYB_domain        + More
IPR009072   Histone-fold       
IPR042225   Ncb2       

SUPFAM

SSF47113   SSF47113       

Gene 3D

1.10.20.10    

ProteinModelPortal

H9J9J9   S4PH31   A0A194R2K6   A0A212F0S4   A0A2H1WCZ5   A0A1E1WIC4   + More
A0A2W1BM42   A0A2A4JFE6   A0A194PLN0   A0A1A9VLY2   A0A1B0AUG4   A0A1B0AFH5   A0A1A9X5H4   D3TLC0   A0A1I8PGM1   A0A1I8NH17   W8BAG3   A0A0L0C1S7   Q16XU3   A0A1Q3FD22   B0WQA9   A0A034V096   A0A0K8TZ04   A0A336M126   A0A023EIT3   B4KLC5   B4LRY7   A0A0K8TR38   B4MZ75   A0A1W4W022   B4HXL1   B4Q5Y6   Q9VJQ5   B4P0X1   Q29P65   B4GK73   A0A0M4EGB6   A0A3B0K741   B3N5M7   B3MLD1   A0A0A1XCD1   U5EXT9  

PDB

1JFI     E-value=2.74969e-37,     Score=385

KEGG

101736852    K21751 down-regulator of transcription 1 | (RefSeq) protein Dr1

GO

GO:0046982   GO:0005634   GO:0045944   GO:0000122   GO:0008134   GO:0001047   GO:0006366   GO:0005671   GO:0042766   GO:0004402   GO:0016573   GO:0045893   GO:0045892   GO:0006338   GO:0008479   GO:0008616   GO:0008033   GO:0043565   GO:0043401   GO:0003677   GO:0003707   GO:0004651  

PANTHER

PTHR46138  

Subcellular location

Nucleus  

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02900

outside

1  -  184

 

 

Pi

172.16156

Theta

188.024795

Tajima's D

-0.379886

CLR

0

CSRT

0.274136293185341

Interpretation

Uncertain