Gene

KWMTBOMO01875

Pre Gene Modal

BGIBMGA005952

Annotation

PREDICTED:_protein_kinase_DC2_[Bombyx_mori]

Location

Bomo_Chr4(-):7198713-7210708      View in EpiBrowser

Full name

cAMP-dependent protein kinase catalytic subunit 3      

Alternative Name

Protein kinase DC2

Location in the cell

Nuclear   Reliability : 2.058

CDS

ATGGGCAGCATTTCGGAGATTGTCTCGGCGCTAGAATACTTACACGCGAGGAACATAGTTTACCGGGATCTAAAACCAGAGAATTTACTGTTAGCCAAAGAGGGCCACCTGAAAATCACAGATTTCGGTTTCGCGAAGAAACTGACCGATCGCACATGGACTTTGTGTGGGACACCCGAATATCTGGCGCCGGAGATCATACAGAGCAAGGGACATAACAAGGCCGTCGACTGGTGGGCTTTGGGTGTTCTTATTTACGAGATGTTGGTCGGGTACCCACCTTTCTACGACGATAATCCCTTCGGAATATATGAGAAGATTCTAAATGGCCGCGTCGAATGGCCTCGGCATTTGGACCCTGTGGCCAAGGACATCATTAAGAAGCTCTTAGTACAAGACAGAACGAAAAGATTGGGCAATATGAAGTGTGGCACGGAAGACGTGAAACGACACAGATGGTTCAAGCATTTGGACTGGGCCGATGTCTACATGAAGAAACTGCAGCCGCCAATAATACCTTCTGTGTCATACGAAGGGGACACATCCAACTTTGACGAGTACCCGGAAACAGATTGGAAATCGGTCCGATCTCTCGACCCCGAAGAATTGAAATTATTCGCCAACTTTTGA

Protein

MGSISEIVSALEYLHARNIVYRDLKPENLLLAKEGHLKITDFGFAKKLTDRTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDDNPFGIYEKILNGRVEWPRHLDPVAKDIIKKLLVQDRTKRLGNMKCGTEDVKRHRWFKHLDWADVYMKKLQPPIIPSVSYEGDTSNFDEYPETDWKSVRSLDPEELKLFANF

Description

Does not have an essential role in development.

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Similarity

Belongs to the protein kinase superfamily.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Belongs to the peptidase C54 family.

Keywords

Alternative splicing   ATP-binding   Complete proteome   Kinase   Nucleotide-binding   Reference proteome   Transferase  

Feature

chain  cAMP-dependent protein kinase catalytic subunit 3
splice variant  In isoform A.

Uniprot

H9J8W0   A0A2A4JHC6   A0A2W1BPM3   A0A212F0V3   A0A0L7L867   A0A194R3D4   + More
A0A194PKQ2   J3JXC9   N6U939   D6WKH0   A0A1Y1NIM1   A0A1W4WZF8   Q16NW2   A0A2J7RMW2   A0A067QE52   A0A1S4FUH0   A0A1Q3G2C3   A0A034WCF4   W8B1Q2   A0A0A1WGQ9   A0A182KAJ8   A0A182W1Y8   A0A1B6DKV2   A0A1B6DJA4   A0A1S3D5G6   Q7PZC6   A0A182L4Y3   A0A182V1V3   A0A182Y9C0   A0A182FUZ0   A0A164WEC6   A0A084WIT2   A0A182N3X5   A0A182XGT5   A0A0P6JP33   A0A182UG97   A0A182HHF2   A0A0P5X827   A0A182R8T6   A0A0R3P3P4   A0A3Q0J1T5   A0A1B6LTA1   A0A023F3H8   B4J1W0   A0A182IQZ2   A0A0N7Z8X8   T1I8D4   W5JXD4   A0A2M4BUV3   A0A0Q5U5F8   A0A1B6IK76   A0A0R1E886   Q194S5   P16912-2   A0A0J9RVZ6   A0A0R1E1T6   A0A3Q0IWP8   A0A2M4AYA3   A0A1I8NF23   B5DPG8   B4MXV4   A0A1B6HWE6   B3M9V2   A0A1W4VMU7   T1PE60   A0A3B0JSB2   A0A2M4CT92   A0A2M4CRC5   P16912   B4KY84   A0A0J9RWB2   A0A0P4WAE5   A0A1B0B1D6   A0A0P8XUP1   B4PD13   B3NDN9   A0A146LL21   B4ITX2   A0A1B6FFS0   A0A1A9VHN0   A0A1A9XSS2   B4GRJ8   A0A1L8DM89   A0A1W4VAT8   A0A182LSH5   A0A1Q3F9C7   A0A0P5BN09   A0A1Q3F9D0   E0VCM7   A0A210QEP7   A0A0C9RC96   A0A232F236   K7J1Q0   E2APP8   E2BBT2   A0A158NTE4   A0A195B382   A0A0J7KNY1   A0A1I8NF16   A0A154PEB3  

EC Number

2.7.11.1

Pubmed

19121390    28756777    22118469    26227816    26354079    22516182    + More
23537049    18362917    19820115    28004739    17510324    24845553    25348373    24495485    25830018    12364791    20966253    25244985    24438588    15632085    17994087    25474469    27129103    20920257    23761445    17550304    3215511    10731132    12537572    12537569    8601490    22936249    25315136    23185243    18057021    26823975    20566863    28812685    28648823    20075255    20798317    21347285   

EMBL

BABH01004972    BABH01004973    BABH01004974    BABH01004975    NWSH01001584    PCG70792.1    + More
KZ150033    PZC74680.1    AGBW02011047    OWR47334.1    JTDY01002402    KOB71486.1    KQ460870    KPJ11750.1    KQ459601    KPI93907.1    BT127898    AEE62860.1    APGK01037838    APGK01037839    KB740949    KB632347    ENN77171.1    ERL93148.1    KQ971342    EFA03994.1    GEZM01006894    JAV95587.1    CH477805    EAT36043.1    NEVH01002548    PNF42174.1    KK853973    KDQ71472.1    GFDL01001093    JAV33952.1    GAKP01005731    JAC53221.1    GAMC01019369    GAMC01019368    JAB87186.1    GBXI01016220    JAC98071.1    GEDC01011013    JAS26285.1    GEDC01011566    JAS25732.1    AAAB01008986    EAA00324.3    LRGB01001253    KZS13193.1    ATLV01023946    KE525347    KFB50126.1    GDIQ01013351    JAN81386.1    GDIP01076052    JAM27663.1    CH379069    KRT07786.1    GEBQ01013069    JAT26908.1    GBBI01002861    JAC15851.1    CH916366    EDV98040.1    GDKW01002107    JAI54488.1    ACPB03001102    ADMH02000001    ETN68144.1    GGFJ01007407    MBW56548.1    CH954178    KQS44155.1    GECU01020374    JAS87332.1    CH891734    KRK05247.1    X16961    CAA34835.1    AE014296    AY118681    CM002912    KMY99878.1    CM000159    KRK02147.1    GGFK01012371    MBW45692.1    EDY73514.2    KRT07787.1    CH963876    EDW76873.2    GECU01028705    GECU01011069    JAS79001.1    JAS96637.1    CH902618    EDV40143.1    KPU78387.1    KA646969    KA649643    AFP61598.1    OUUW01000009    SPP85017.1    GGFL01004394    MBW68572.1    GGFL01003699    MBW67877.1    CH933809    EDW19803.2    KMY99877.1    GDRN01060215    JAI65410.1    JXJN01007078    KPU78386.1    EDW94945.1    EDV52172.1    GDHC01009865    JAQ08764.1    EDW99835.1    GECZ01028846    GECZ01025638    GECZ01020732    GECZ01005756    JAS40923.1    JAS44131.1    JAS49037.1    JAS64013.1    CH479188    EDW40383.1    GFDF01006634    JAV07450.1    AXCM01004284    GFDL01010918    JAV24127.1    GDIP01187350    JAJ36052.1    GFDL01010937    JAV24108.1    AAZO01001082    DS235060    EEB11133.1    NEDP02004019    OWF47178.1    GBYB01010727    JAG80494.1    NNAY01001239    OXU24642.1    GL441572    EFN64599.1    GL447151    EFN86858.1    ADTU01025865    KQ976625    KYM78953.1    LBMM01004965    KMQ91954.1    KQ434870    KZC09550.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000037510    UP000053240    UP000053268    + More
UP000019118    UP000030742    UP000007266    UP000192223    UP000008820    UP000235965    UP000027135    UP000075881    UP000075920    UP000079169    UP000007062    UP000075882    UP000075903    UP000076408    UP000069272    UP000076858    UP000030765    UP000075884    UP000076407    UP000075902    UP000075900    UP000001819    UP000001070    UP000075880    UP000015103    UP000000673    UP000008711    UP000002282    UP000000803    UP000095301    UP000007798    UP000007801    UP000192221    UP000268350    UP000009192    UP000092460    UP000078200    UP000092443    UP000008744    UP000075883    UP000009046    UP000242188    UP000215335    UP000002358    UP000000311    UP000008237    UP000005205    UP000078540    UP000036403    UP000076502   

PRIDE

H9J8W0    Q194S5    P16912   

Pfam

PF00069   Pkinase        + More
PF02889   Sec63
PF03416   Peptidase_C54

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR000961   AGC-kinase_C       
IPR017441   Protein_kinase_ATP_BS       
IPR004179   Sec63-dom       
IPR038765   Papain-like_cys_pep_sf       
IPR005078   Peptidase_C54       

SUPFAM

SSF56112   SSF56112        + More
SSF54001   SSF54001       

ProteinModelPortal

H9J8W0   A0A2A4JHC6   A0A2W1BPM3   A0A212F0V3   A0A0L7L867   A0A194R3D4   + More
A0A194PKQ2   J3JXC9   N6U939   D6WKH0   A0A1Y1NIM1   A0A1W4WZF8   Q16NW2   A0A2J7RMW2   A0A067QE52   A0A1S4FUH0   A0A1Q3G2C3   A0A034WCF4   W8B1Q2   A0A0A1WGQ9   A0A182KAJ8   A0A182W1Y8   A0A1B6DKV2   A0A1B6DJA4   A0A1S3D5G6   Q7PZC6   A0A182L4Y3   A0A182V1V3   A0A182Y9C0   A0A182FUZ0   A0A164WEC6   A0A084WIT2   A0A182N3X5   A0A182XGT5   A0A0P6JP33   A0A182UG97   A0A182HHF2   A0A0P5X827   A0A182R8T6   A0A0R3P3P4   A0A3Q0J1T5   A0A1B6LTA1   A0A023F3H8   B4J1W0   A0A182IQZ2   A0A0N7Z8X8   T1I8D4   W5JXD4   A0A2M4BUV3   A0A0Q5U5F8   A0A1B6IK76   A0A0R1E886   Q194S5   P16912-2   A0A0J9RVZ6   A0A0R1E1T6   A0A3Q0IWP8   A0A2M4AYA3   A0A1I8NF23   B5DPG8   B4MXV4   A0A1B6HWE6   B3M9V2   A0A1W4VMU7   T1PE60   A0A3B0JSB2   A0A2M4CT92   A0A2M4CRC5   P16912   B4KY84   A0A0J9RWB2   A0A0P4WAE5   A0A1B0B1D6   A0A0P8XUP1   B4PD13   B3NDN9   A0A146LL21   B4ITX2   A0A1B6FFS0   A0A1A9VHN0   A0A1A9XSS2   B4GRJ8   A0A1L8DM89   A0A1W4VAT8   A0A182LSH5   A0A1Q3F9C7   A0A0P5BN09   A0A1Q3F9D0   E0VCM7   A0A210QEP7   A0A0C9RC96   A0A232F236   K7J1Q0   E2APP8   E2BBT2   A0A158NTE4   A0A195B382   A0A0J7KNY1   A0A1I8NF16   A0A154PEB3  

KEGG

101736413    K19584 protein kinase X [EC:2.7.11.11] | (RefSeq) protein kinase DC2

GO

GO:0004674   GO:0005524   GO:0016021   GO:0004691   GO:0006468   GO:0007476   GO:0005737   GO:0008234   GO:0006914   GO:0015031   GO:0004672   GO:0043565   GO:0043401   GO:0003677   GO:0003707   GO:0004651   GO:0005634  

PANTHER

PTHR22624  

Subcellular location

Cytoplasm  

Length:

209

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.56897

Exp number, first 60 AAs:

0.00066

Total prob of N-in:

0.05834

outside

1  -  209

 

 

Pi

208.467866

Theta

142.436388

Tajima's D

0.758217

CLR

0.225219

CSRT

0.593170341482926

Interpretation

Uncertain