Gene

KWMTBOMO01838

Pre Gene Modal

BGIBMGA005972

Annotation

PREDICTED:_tyrosine-protein_kinase_transmembrane_receptor_Ror-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr4(-):5937320-5947715      View in EpiBrowser

Full name

Tyrosine-protein kinase receptor      

Location in the cell

Nuclear   Reliability : 3.653

CDS

ATGCGTGCAAGGCATCGGGGCCATGAAGAAAATCTGACGAGGTTTGCCAGAGATGAATTGAATCTGGAAGAAAATTCGGAGCCACGACCAATTAAATACTTTCAAGGAGCTTGCGAGCCGATGTCCTGTGGAGAAGAAGCTGCGTGTACGGAATACAACAGTACCGTTCATTTCTGTTGGTGCACGACCACCGGAATGCCCATTACTGAGGACTTGCAATGCCCAAGAAGTCCAGTGACGGCAACTCCTAAACCGATCCATAATGTGATTCCGCCGCAGACTCGCACCACTAACACATTCGACGGAAGAAACGCGCCTTCACCGCCAACTGCTCAATTCAGTGGAGAAGTTTTGGCGGAAGCAACGACTGGAAATGAACCAAATGTTGTGGGAGCCGGTGTACACGTTACAACAGGAGTACTTCTGGCAGCTCTAGTTAGTGGAGCATTACTTCTTTTGTTCGTGGTATCTATTCTAGTTTGGTACTTTAGACGAAGGATATGTCGCGTCGATGGAAAAACTCAGCCGCGAGTGCGGCCAGGAGAGCCTCTTCTCGCTGAAAGGTATATAACGAACCCCCAGTACGGTGTGTACGGAGCCGGCGCGACCGCGACCGGCACGGGTCCGGCGAACGGACCGATTGTCGACGACACTACAGAACCCAGAGTACCTCTCTTAGATAGAAGCGCTTTGACATTCCTCGAAGAAGTCGGTGAAGGATGTTTTGGCAAGGTGCACAGAGGTTTGCTTCGAGTAAATGACTTGGAACAAGAAGTCGCAATTAAGGTTCTGAAAGAAAGCGCTGGACGCAGCGCCGAAGAGGAATTCATACGAGAGGTTTCAATAATGTCTGCATTTAGACATTCAAATATTCTTACTCTAGTCGGAGTGGTCTATAAAGATAATGTTATATGCAGCCCTTGGATGGTGTTTGAATATATGGAGCTGGGTGATTTGGCCGGTGTCCTGAGGGGGTCTCGCAATGGTGTTCGACCTGCACCCACGCTGAACGAAGTTGCTCTCTTACACGTAGCGCTACAAGTTGCGAGGGGCATGCAATACCTCGCTTCCCGCAGATTTGTCCACCGTGATTTAGCTGCCAGAAACTGTTTGGTCGGATCTCATCTTACAGTTAAGATAGCTGACTTTGGAATGTCCAGAGACGTTTACACTTGTGATTATTACAAAATGGGCGGTGAACGTCCAATGCCAGTACGGTGGATGTCTCCGGAGAGCATTCTGTACGCACGTTTTACTCACGAATCAGACGTGTGGGCGTATGGTGTCGTACTCTGGGAGATATACAGCCGAGGCAAACAACCATTTTATGGGCATAATAACGAAGATGCCACAAAGCTAATCGTACAGGGTATTTTGTTGGTGCCGCCAGAAGAATGTCCTCGGTTTGCTTGCGAGTTGATGCGCGAATGCTGGCAGTTCGATCCACAAAATAGGATCGATTTTGATGAGATTTGTAGAAAATTAGAAATAGCTGCGGCCGGTGGTACTACGACCGAGCAAGTGCGACTGCCGCGACCACCAAATCCTTCTCAAGATTCTGCTGGGTATCTGATCCCGGCGCGGCAAACTCCAGTTGATTATCTGACTTTATTGTTAGGTGATGAAAATCATGAGCCCGAATCTGAGTCTAGTGAAGAAGAGGAAGACGAAGAAGAGTATACTTGA

Protein

MRARHRGHEENLTRFARDELNLEENSEPRPIKYFQGACEPMSCGEEAACTEYNSTVHFCWCTTTGMPITEDLQCPRSPVTATPKPIHNVIPPQTRTTNTFDGRNAPSPPTAQFSGEVLAEATTGNEPNVVGAGVHVTTGVLLAALVSGALLLLFVVSILVWYFRRRICRVDGKTQPRVRPGEPLLAERYITNPQYGVYGAGATATGTGPANGPIVDDTTEPRVPLLDRSALTFLEEVGEGCFGKVHRGLLRVNDLEQEVAIKVLKESAGRSAEEEFIREVSIMSAFRHSNILTLVGVVYKDNVICSPWMVFEYMELGDLAGVLRGSRNGVRPAPTLNEVALLHVALQVARGMQYLASRRFVHRDLAARNCLVGSHLTVKIADFGMSRDVYTCDYYKMGGERPMPVRWMSPESILYARFTHESDVWAYGVVLWEIYSRGKQPFYGHNNEDATKLIVQGILLVPPEECPRFACELMRECWQFDPQNRIDFDEICRKLEIAAAGGTTTEQVRLPRPPNPSQDSAGYLIPARQTPVDYLTLLLGDENHEPESESSEEEEDEEEYT

Catalytic Activity

ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

Uniprot

H9J8Y0   A0A194R3X1   A0A194PKH6   A0A3S2NKJ8   A0A2A4KAF4   A0A212F626   + More
A0A232EGX7   A0A1B6CKF4   A0A1B6KVD3   K7IPU6   A0A0L7R180   T1IAV2   A0A067RMT3   E2BLZ5   A0A0C9R5T8   A0A195BWX7   A0A195F1B4   A0A151IH99   A0A154NY25   A0A158P3J9   A0A2A3EGD4   A0A1Y1M813   A0A088ANR5   A0A1W4XB69   A0A151XE00   A0A0C9PQ15   F4WAT0   E9IEA7   A0A2P8YTG8   A0A224XQN1   A0A2H8TK98   A0A2R4G8U5   A0A0A9XGS5   A0A0K8ST81   J9JNV6   A0A2R7WVB6   A0A151IV50   A0A164UE11   A0A0N8CXK0   A0A0P5NAT6   A0A0N8BIW8   T1KK75   A0A0P6DY13   A0A0P6B4T2   A0A0P5T1Y6   A0A226F556   A0A0P4Y789  

EC Number

2.7.10.1

Pubmed

19121390    26354079    22118469    28648823    20075255    24845553    + More
20798317    21347285    28004739    21719571    21282665    29403074    25401762    26823975   

EMBL

BABH01004867    KQ460855    KPJ11940.1    KQ459601    KPI93941.1    RSAL01000014    + More
RVE53286.1    NWSH01000024    PCG80632.1    AGBW02010086    OWR49183.1    NNAY01004651    OXU17605.1    GEDC01023445    JAS13853.1    GEBQ01024584    JAT15393.1    KQ414668    KOC64551.1    ACPB03006705    KK852415    KDR24363.1    GL449088    EFN83281.1    GBYB01003294    GBYB01003296    GBYB01003300    JAG73061.1    JAG73063.1    JAG73067.1    KQ976394    KYM93134.1    KQ981880    KYN33894.1    KQ977636    KYN01139.1    KQ434782    KZC04523.1    ADTU01008164    KZ288254    PBC30768.1    GEZM01041377    JAV80465.1    KQ982268    KYQ58478.1    GBYB01003293    GBYB01003295    JAG73060.1    JAG73062.1    GL888053    EGI68686.1    GL762576    EFZ21082.1    PYGN01000369    PSN47551.1    GFTR01006147    JAW10279.1    GFXV01002750    MBW14555.1    MF620046    AVT56268.1    GBHO01029468    GBHO01024450    GDHC01017328    JAG14136.1    JAG19154.1    JAQ01301.1    GBRD01009789    JAG56035.1    ABLF02023652    ABLF02023653    ABLF02023656    ABLF02023657    KK855629    PTY23341.1    KQ980924    KYN11407.1    LRGB01001581    KZS11277.1    GDIP01089047    JAM14668.1    GDIQ01155674    JAK96051.1    GDIQ01173315    JAK78410.1    CAEY01000173    CAEY01000174    CAEY01000175    GDIQ01071443    JAN23294.1    GDIP01020165    JAM83550.1    GDIP01132200    LRGB01001361    JAL71514.1    KZS12229.1    LNIX01000001    OXA64587.1    GDIP01232573    JAI90828.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000283053    UP000218220    UP000007151    + More
UP000215335    UP000002358    UP000053825    UP000015103    UP000027135    UP000008237    UP000078540    UP000078541    UP000078542    UP000076502    UP000005205    UP000242457    UP000005203    UP000192223    UP000075809    UP000007755    UP000245037    UP000007819    UP000078492    UP000076858    UP000015104    UP000198287   

PRIDE

H9J8Y0   

Pfam

PF07714   Pkinase_Tyr

Interpro

IPR008266   Tyr_kinase_AS        + More
IPR020635   Tyr_kinase_cat_dom       
IPR000719   Prot_kinase_dom       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       
IPR000742   EGF-like_dom       
IPR002011   Tyr_kinase_rcpt_2_CS       

SUPFAM

SSF56112   SSF56112       

ProteinModelPortal

H9J8Y0   A0A194R3X1   A0A194PKH6   A0A3S2NKJ8   A0A2A4KAF4   A0A212F626   + More
A0A232EGX7   A0A1B6CKF4   A0A1B6KVD3   K7IPU6   A0A0L7R180   T1IAV2   A0A067RMT3   E2BLZ5   A0A0C9R5T8   A0A195BWX7   A0A195F1B4   A0A151IH99   A0A154NY25   A0A158P3J9   A0A2A3EGD4   A0A1Y1M813   A0A088ANR5   A0A1W4XB69   A0A151XE00   A0A0C9PQ15   F4WAT0   E9IEA7   A0A2P8YTG8   A0A224XQN1   A0A2H8TK98   A0A2R4G8U5   A0A0A9XGS5   A0A0K8ST81   J9JNV6   A0A2R7WVB6   A0A151IV50   A0A164UE11   A0A0N8CXK0   A0A0P5NAT6   A0A0N8BIW8   T1KK75   A0A0P6DY13   A0A0P6B4T2   A0A0P5T1Y6   A0A226F556   A0A0P4Y789  

KEGG

101741538    no KO assigned | (RefSeq) tyrosine-protein kinase transmembrane receptor Ror-like

GO

GO:0004713   GO:0016021   GO:0005524   GO:0007169   GO:0004714   GO:0006468   GO:0004672   GO:0006357   GO:0032784   GO:0006355   GO:0006397   GO:0004651   GO:0005634  

Length:

561

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.88053

Exp number, first 60 AAs:

0.00061

Total prob of N-in:

0.90107

inside

1  -  140

TMhelix

141  -  163

outside

164  -  561

 

 

Pi

221.33364

Theta

207.086708

Tajima's D

1.548623

CLR

0.13215

CSRT

0.79946002699865

Interpretation

Uncertain