Gene

KWMTBOMO01835

Annotation

PREDICTED:_venom_acid_phosphatase_Acph-1-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr4(+):5886156-5894221      View in EpiBrowser

Full name

Venom acid phosphatase Acph-1      

Location in the cell

Lysosomal   Reliability : 1.342

CDS

ATGTCATGTGTAGATAAGTACTGTGGTATAATCGATTGGGCAAAGTCAATCATCATAGGTCGCAGCGACCGTGAATCTCCCACACAATTGGAATACAATGTAGAGGTGCCGACTCGGCGTAGAAAAATGAAAGAGGGCGGTCGCGAGGAGGAGCCGACCAACGCGCCGGAAGCTACACCGGCACCGGGTATGCGCACCGAACACACTTGCTGTTGCCTCGGCGTGTTGGTGGGCATCTCGCTCATAGCCGCCCTCGTAGCAGTAATACTGATGAAGGATACTACGGTAGAAGTCACAATACTTCGACAGGTACATGTGTTGATGTCTCATGGCGAGAGGACTCCAAGTGAACGCGAACTCGAAATGTTAGGAACAAGTCCTCCAGAGCATGTGTTTTCACCTTACGGCGCTGGTGCTATGACAAATGAAGGAAAAATGTTGACTTTCGAAATGGGCGCATTACTTAGAAAGAGATATAACGATTTCTTAGGACCACTTTACGACGCAGAAAGCAGTATCGTTATAGCCTCAGATACAAATTTAAGTAAGATGACAGCTCTGCTGATATCGGCTGGATTGTGGCCGCCGCCGGAAGAGCAGCTCTGGAATGACACAATCGTGTGGCAGCCGGTACCTTACAAATATCCGCCACAAAGCAATGATTTTCTTCTGTACGAAAAAAATTGTCCACGTTATAAACAAGAAAAAGGAAGAATATTGAATGCGTTCGTCGATGAAGGCGTGCTGGTGCCGTATCGGGATCTGTTTCATAAAATTGCGCAAATGACGAACACGAATTTTAGCACACCACAAGAGGCTTATTTCTTAAACAACTTATTTCTTATACAGGACGATATCAAAGTGGCAAATCCGAAATGGGCAAAACACGTTAAAAGGAAATTGATGGACATCGCCCGTCTTGAATACTCAATGATGTTTCACAACAATCTTTTAAGGAAATTGAGTGGCGGGGCTTTATTACATCAAATAATAAAGGAAGCCGTTTCGAACGCATTGGGAGCATCGCGGTTACGCATGATCGTACGCACGGGCACGCCCGTATCCGTGGCAGCCGTGCTGGCGGCGTGCGTGGCGCCGCCGCCGCGTCTCCCCGACCCCGGGGCCGCGTTACTATTCGAACTACACGAACGACAACCGAATAAAGGAAAAAACGAACCATCACTCAACGACGAGCAACGTTTCGGATTTAAGATCTATTACTGGGACGATGATTCAGCTGAACCTCGTCTCATGGAAGTGCCCAATTGCAATTCCTTCTGCACGATTGAACAATTCAAAGAGTTAACGAAATACATAATTGCCCATAATTATGAAGAAGACTGTAAGCTCGTTGCGGAACAAACCAATTGA

Protein

MSCVDKYCGIIDWAKSIIIGRSDRESPTQLEYNVEVPTRRRKMKEGGREEEPTNAPEATPAPGMRTEHTCCCLGVLVGISLIAALVAVILMKDTTVEVTILRQVHVLMSHGERTPSERELEMLGTSPPEHVFSPYGAGAMTNEGKMLTFEMGALLRKRYNDFLGPLYDAESSIVIASDTNLSKMTALLISAGLWPPPEEQLWNDTIVWQPVPYKYPPQSNDFLLYEKNCPRYKQEKGRILNAFVDEGVLVPYRDLFHKIAQMTNTNFSTPQEAYFLNNLFLIQDDIKVANPKWAKHVKRKLMDIARLEYSMMFHNNLLRKLSGGALLHQIIKEAVSNALGASRLRMIVRTGTPVSVAAVLAACVAPPPRLPDPGAALLFELHERQPNKGKNEPSLNDEQRFGFKIYYWDDDSAEPRLMEVPNCNSFCTIEQFKELTKYIIAHNYEEDCKLVAEQTN

Catalytic Activity

a phosphate monoester + H2O = an alcohol + phosphate

Similarity

Belongs to the histidine acid phosphatase family.

Keywords

Allergen   Complete proteome   Direct protein sequencing   Disulfide bond   Glycoprotein   Hydrolase   Reference proteome   Secreted   Signal  

Feature

chain  Venom acid phosphatase Acph-1

Uniprot

A0A2A4K8T7   A0A2H1WGF6   A0A212F617   A0A3S2NZR1   A0A194R2C4   A0A194PLS5   + More
H9J9I3   A0A194R7T8   A0A0L7QWI3   A0A067QNZ9   A0A194PS41   A0A2A4K986   A0A212F630   A0A0K8TLP0   K7IZV4   D2A1N0   D2A1N1   D6WAI2   J9K623   Q0PWU9   U4U626   A0A3S2LGG3   A0A1W6EVT0   A0A1S3D5K3   J3JZ60   A0A1S3D5S2   E2C1V8   A0A2S2QXE2   A0A0A9XGP6   A0A146MAA4   F4WFK0   A0A0T6B3P5   A0A3L8DX27   A0A158NSL2   A0A151HZE5   A0A1Y1N416   A0A1L8DYV9   K7IZV5   E2ARU9   E2B168   A0A1B6F055   D3TNZ8   A0A1B6MG81   A0A2A3E9C8   D2A1N2   A0A310SKW5   A0A1L8DZ06   A0A2R4SV17   A0A1Q3EW11   A0A1Q3EW78   A0A1J1I6C6   A0A195FSS6   E9JD78   C1IC99   A0A1A9ZSA2   A0A1Y1N7Z4   A0A1A9WGA5   K7IQ61   A0A0C9R287   A0A1B6JWK6   Q5BLY5   A0A1Q3EVW7   D6WAI1   A0A1Q3EVW8   A0A336L3V8   A0A087ZRC7   A0A1B0GD38   A0A2A3E9H3   A0A023EQR2   N6SVB5   E2C1V9   A0A1B0BCK4   A0A026WAD8   A0A0L7QKE0   A0A088AJL8   A0A232EEI8   A0A154PQI5   A0A2P8YES0   U4UM22   A0A154PK09   A0A060GL20   A0A0M9AAI3   K7IQ63   J3JUU6   A0A170XK82   A0A0L7RCP2   A0A170XK51   E2ABY7   A0A1Y1LK10   A0A1W6EVW2   A0A1W7R8D5   A0A0C9S0C4   A0A0J7KGP1   A0A154P094   A0A154P3P1   A0A310SN00   A0A0C9RY44  

EC Number

3.1.3.2

Pubmed

22118469    26354079    19121390    24845553    26369729    20075255    + More
18362917    19820115    23537049    22516182    20798317    25401762    26823975    21719571    30249741    21347285    28004739    20353571    21282665    18448143    17073008    16630944    16645223    24945155    24508170    28648823    29403074   

EMBL

NWSH01000024    PCG80631.1    ODYU01008500    SOQ52158.1    AGBW02010086    OWR49185.1    + More
RSAL01000014    RVE53288.1    KQ460855    KPJ11938.1    KQ459601    KPI93943.1    BABH01004863    KPJ11936.1    KQ414714    KOC62926.1    KK853123    KDR11063.1    KPI93945.1    PCG80629.1    OWR49186.1    GDAI01002763    JAI14840.1    KQ971338    EFA02696.1    EFA02697.1    KQ971312    EEZ98635.1    ABLF02019532    DQ675545    ABG74711.1    KB632166    ERL89324.1    RVE53289.1    KY563421    ARK19830.1    APGK01027827    APGK01027828    BT128541    KB740671    KB631972    AEE63498.1    ENN79637.1    ERL87551.1    GL452008    EFN78070.1    GGMS01013238    MBY82441.1    GBHO01024763    JAG18841.1    GDHC01001938    JAQ16691.1    GL888120    EGI66977.1    LJIG01015968    KRT82010.1    QOIP01000003    RLU24852.1    ADTU01024956    ADTU01024957    KQ976719    KYM76739.1    GEZM01013380    GEZM01013379    JAV92604.1    GFDF01002423    JAV11661.1    GL442175    EFN63832.1    GL444789    EFN60592.1    GECZ01026189    JAS43580.1    EZ423150    ADD19426.1    GEBQ01005053    JAT34924.1    KZ288340    PBC27776.1    EFA02698.1    KQ762882    OAD55311.1    GFDF01002425    JAV11659.1    MF319183    AVZ66237.1    GFDL01015589    JAV19456.1    GFDL01015587    JAV19458.1    CVRI01000042    CRK95747.1    KQ981276    KYN43496.1    GL771866    EFZ09215.1    EU365869    ACA60733.1    GEZM01013669    JAV92386.1    GBYB01006952    JAG76719.1    GECU01004413    JAT03294.1    AY939855    FJ200211    DQ058012    GFDL01015588    JAV19457.1    EEZ98634.1    GFDL01015590    JAV19455.1    UFQS01001870    UFQT01001870    SSX12606.1    SSX32049.1    CCAG010002313    CCAG010002314    KZ288322    PBC28124.1    GAPW01001661    JAC11937.1    APGK01055292    APGK01055293    KB741261    ENN71644.1    EFN78071.1    JXJN01012024    KK107295    EZA53020.1    RLU24854.1    KQ414954    KOC59082.1    NNAY01005308    OXU16770.1    KQ435041    KZC14176.1    PYGN01000655    PSN42750.1    KB632278    ERL91221.1    KQ434943    KZC12199.1    KJ710422    AIB53032.1    KQ435699    KOX80575.1    BT127011    AEE61973.1    GEMB01004321    JAR98952.1    KQ414615    KOC68575.1    GEMB01004322    JAR98951.1    GL438386    EFN69082.1    GEZM01057530    JAV72275.1    KY563442    ARK19851.1    GEHC01000248    JAV47397.1    GBYB01001906    GBYB01015265    JAG71673.1    JAG85032.1    LBMM01007630    KMQ89563.1    KQ434787    KZC05263.1    KQ434796    KZC05750.1    KQ762196    OAD56135.1    GBYB01012831    JAG82598.1   

Proteomes

UP000218220    UP000007151    UP000283053    UP000053240    UP000053268    UP000005204    + More
UP000053825    UP000027135    UP000002358    UP000007266    UP000007819    UP000030742    UP000079169    UP000019118    UP000008237    UP000007755    UP000279307    UP000005205    UP000078540    UP000000311    UP000242457    UP000183832    UP000078541    UP000092445    UP000091820    UP000005203    UP000092444    UP000092460    UP000053097    UP000215335    UP000076502    UP000245037    UP000053105    UP000036403   

PRIDE

H9J9I3   

Pfam

PF00328   His_Phos_2        + More
PF01395   PBP_GOBP

Interpro

IPR000560   His_Pase_clade-2        + More
IPR029033   His_PPase_superfam       
IPR029630   Api_m_3       
IPR033379   Acid_Pase_AS       
IPR036728   PBP_GOBP_sf       
IPR006170   PBP/GOBP       

SUPFAM

SSF53254   SSF53254        + More
SSF47565   SSF47565       

Gene 3D

3.40.50.1240     1.10.238.20    

CDD

cd07061  HP_HAP_like

ProteinModelPortal

A0A2A4K8T7   A0A2H1WGF6   A0A212F617   A0A3S2NZR1   A0A194R2C4   A0A194PLS5   + More
H9J9I3   A0A194R7T8   A0A0L7QWI3   A0A067QNZ9   A0A194PS41   A0A2A4K986   A0A212F630   A0A0K8TLP0   K7IZV4   D2A1N0   D2A1N1   D6WAI2   J9K623   Q0PWU9   U4U626   A0A3S2LGG3   A0A1W6EVT0   A0A1S3D5K3   J3JZ60   A0A1S3D5S2   E2C1V8   A0A2S2QXE2   A0A0A9XGP6   A0A146MAA4   F4WFK0   A0A0T6B3P5   A0A3L8DX27   A0A158NSL2   A0A151HZE5   A0A1Y1N416   A0A1L8DYV9   K7IZV5   E2ARU9   E2B168   A0A1B6F055   D3TNZ8   A0A1B6MG81   A0A2A3E9C8   D2A1N2   A0A310SKW5   A0A1L8DZ06   A0A2R4SV17   A0A1Q3EW11   A0A1Q3EW78   A0A1J1I6C6   A0A195FSS6   E9JD78   C1IC99   A0A1A9ZSA2   A0A1Y1N7Z4   A0A1A9WGA5   K7IQ61   A0A0C9R287   A0A1B6JWK6   Q5BLY5   A0A1Q3EVW7   D6WAI1   A0A1Q3EVW8   A0A336L3V8   A0A087ZRC7   A0A1B0GD38   A0A2A3E9H3   A0A023EQR2   N6SVB5   E2C1V9   A0A1B0BCK4   A0A026WAD8   A0A0L7QKE0   A0A088AJL8   A0A232EEI8   A0A154PQI5   A0A2P8YES0   U4UM22   A0A154PK09   A0A060GL20   A0A0M9AAI3   K7IQ63   J3JUU6   A0A170XK82   A0A0L7RCP2   A0A170XK51   E2ABY7   A0A1Y1LK10   A0A1W6EVW2   A0A1W7R8D5   A0A0C9S0C4   A0A0J7KGP1   A0A154P094   A0A154P3P1   A0A310SN00   A0A0C9RY44  

PDB

1ND6     E-value=4.93219e-23,     Score=267

KEGG

101745434    K19283 prostatic aicd phosphatase [EC:3.1.3.2 3.1.3.5] | (RefSeq) venom acid phosphatase Acph-1-like

GO

GO:0016021   GO:0003993   GO:0005549   GO:0005576   GO:0043169   GO:0003676   GO:0008270   GO:0006357   GO:0032784   GO:0006355   GO:0006397   GO:0004651   GO:0005634  

PANTHER

PTHR11567:SF183  

Subcellular location

Secreted  

Length:

456

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.57503

Exp number, first 60 AAs:

0

Total prob of N-in:

0.98871

inside

1  -  68

TMhelix

69  -  91

outside

92  -  456

 

 

Pi

237.891324

Theta

168.421856

Tajima's D

0.904625

CLR

0.589076

CSRT

0.630418479076046

Interpretation

Uncertain