SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01825  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA005981
Annotation
immune-related_protein_2_precursor_[Bombyx_mori]
Full name
Putative defense protein Hdd11-like       + More
Putative defense protein Hdd11      
Putative defense protein 1      
Putative defense protein      
Putative defense protein 2      
Putative defense protein 3      
Alternative Name
Hyphantria differentially displayed gene 11
Location in the cell
Cytoplasmic   Reliability : 1.341 PlasmaMembrane   Reliability : 1.019
 

Sequence

CDS
ATGCGTTTCTTATATGCTGTCGGTGTACTTTGCGTGGCGTCTTATGCCAACGCATATTCTTCTGGGGCACCAGAGAGTGCATGCATTGACATGATCCCGAAGCATCCTGTCAGTCCTCAAACGTCTACACCACCTTACACCATTACAACCAGCACAAAGACAGTCAAAGCCGGTACTCCCATGGAAGTTGTGATCAGCGGTAACAAGCCAGAGAACATTATACGCGGTCTGCTGCTCGAAGCCCGCCAGGGAAACAATATTGTCGGCAAGTTCACTTTGAACCCTAACGACCAATTCGCGAAACTACTCAATTGCGGCGAGCCTGGAAATGCAGTGACTCACAAGAAGCACGATGAACAATATGACAAACAAACTGTTGCGTATACTTGGACTCCACCTGTGGGCTTCAACGACGAAATCAAATTCAGAGCTACCGTGGCCTACAACGGCGCAAAGTTTTGGGTGGGATTAGAATCTGCACCAGTTAAAGTTATTAATTAA
Protein
MRFLYAVGVLCVASYANAYSSGAPESACIDMIPKHPVSPQTSTPPYTITTSTKTVKAGTPMEVVISGNKPENIIRGLLLEARQGNNIVGKFTLNPNDQFAKLLNCGEPGNAVTHKKHDEQYDKQTVAYTWTPPVGFNDEIKFRATVAYNGAKFWVGLESAPVKVIN

Summary

Description
May have antimicrobial activity.
As this protein is expressed upon bacterial infection, it may have antimicrobial activity.
Similarity
Belongs to the insect defense protein family.
Keywords
Antibiotic   Antimicrobial   Disulfide bond   Glycoprotein   Immunity   Innate immunity   Secreted   Signal   Complete proteome   Reference proteome  
Feature
chain  Putative defense protein Hdd11-like
EMBL
HQ325058    ADZ40415.1    BABH01004850    NWSH01000024    PCG80618.1    RBVL01000219    + More
RKO10500.1    AF413066    AF034999    ODYU01010122    SOQ55009.1    AK401228    BAM17850.1    KQ459601    KPI93955.1    KF146179    AGV28583.1    AGBW02013714    OWR42927.1    AB115556    DQ666501    HQ325059    ADZ40416.1    DQ898221    KQ460855    KPJ11927.1    KP208617    AJW81891.1    AY829736    KJ913669    AIC33904.1    DQ666502    UFQS01000222    UFQT01000222    SSX01578.1    SSX21958.1    UFQT01000634    SSX25952.1    JXUM01040107    JXUM01040108    JXUM01040109    JXUM01040110    KQ561232    KXJ79288.1    GDUN01000851    JAN95068.1    DS231884    EDS43062.1    GFDL01015398    JAV19647.1    KK852860    KDR14834.1    DS235226    EEB13623.1    ATLV01018379    KE525231    KFB43072.1    GGFJ01010012    MBW59153.1    ADMH02002160    ETN58185.1    GGFK01012505    MBW45826.1    GGFK01011104    MBW44425.1    KC355218    AGK40918.1    BT128316    KB632348    AEE63274.1    ERL93165.1    AXCM01000336    GEHC01000606    JAV47039.1    GGFJ01010013    MBW59154.1    ETN58183.1    AXCN02002086    AAAB01008984    EAA14972.3    EF638941    ABR27826.1    CVRI01000054    CRL00397.1    GGFK01011669    MBW44990.1    APGK01037236    APGK01037237    KB740948    ENN77284.1    APCN01003368    GAPW01005156    JAC08442.1    KZ149970    PZC76089.1    GAMD01001298    JAB00293.1    ACPB03014845    NWSH01001563    PCG70855.1    GAMD01002736    JAA98854.1    CH902620    EDV31555.1    GEZM01080740    JAV62061.1    GFTR01002723    JAW13703.1    CH477641    EAT37910.1    GGFK01006085    MBW39406.1    KQ971343    EFA03146.1    GDHC01005992    JAQ12637.1    GBHO01008560    GBHO01008559    JAG35044.1    JAG35045.1    CH479195    EDW27397.1    GEMB01003256    JAR99957.1    CP012523    ALC39942.1    KQ459166    KPJ03545.1    BABH01018561    BABH01018562    BABH01018563    BABH01018564    BABH01018565    ATLV01019596    KE525275    KFB44361.1    CH477385    EAT42111.1    AK402994    BAM19505.1    EAT42110.1    KL873122    KGL97856.1    RJVU01044706    ROL44760.1    CH954177    EDV58575.1    KK459392    KFQ78238.1    CH933807    EDW11866.1    KL341159    KFZ53026.1    KK660750    KFQ08046.1    CH379061    EAL33259.1    KRT04859.1    JXUM01112707    JXUM01112708    GAPW01000489    KQ565616    JAC13109.1    KXJ70842.1    AGBW02008868    OWR52331.1    KL382133    KFP88006.1    GAPW01000746    JAC12852.1    JXUM01027162    KQ560781    KXJ80916.1    KRT04858.1    GAPW01000736    JAC12862.1    CM000157    EDW88996.1   
Pfam
PF02014   Reeler        + More
PF03351   DOMON
PF03188   Cytochrom_B561
PF07542   ATP12
PF06202   GDE_C
PF14699   hGDE_N
PF14702   hGDE_central
PF14701   hDGE_amylase
Interpro
IPR002861   Reeler_dom        + More
IPR042307   Reeler_sf       
IPR005018   DOMON_domain       
IPR006593   Cyt_b561/ferric_Rdtase_TM       
IPR023335   ATP12_ortho_dom_sf       
IPR042272   ATP12_ATP_synth-F1-assembly_N       
IPR011419   ATP12_ATP_synth-F1-assembly       
IPR032792   AGL_glucanoTrfase       
IPR017853   Glycoside_hydrolase_SF       
IPR006421   Glycogen_debranch_met       
IPR029436   AGL_euk_N       
IPR010401   AGL/Gdb1       
IPR032790   GDE_C       
IPR032788   AGL_central       
IPR008928   6-hairpin_glycosidase_sf       
SUPFAM
SSF48208   SSF48208        + More
SSF51445   SSF51445       

Ontologies

Topology

Subcellular location
Secreted  
SignalP
Position:   1 - 18,         Likelihood:  0.998666
 
 
Length:
166
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.525989999999999
Exp number, first 60 AAs:
0.52477
Total prob of N-in:
0.06005
outside
1  -  166
 
 

Population Genetic Test Statistics

Pi
287.123617
Theta
19.402192
Tajima's D
0.294889
CLR
262.875811
CSRT
0.454327283635818
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28467696 KHAIIEADVSSHAER 100.00 5e-14
28467696 HDEQICEAIVTR 100.00 3e-13
28467696 QTVAVGVIK 100.00 3e-07
28467696 AGTNYIYK 100.00 7e-07
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