Gene

KWMTBOMO01820  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006169

Annotation

PREDICTED:_transformation/transcription_domain-associated_protein_[Papilio_xuthus]

Location

Bomo_Chr4(+):5621222-5653832      View in EpiBrowser

Full name

Transformation/transcription domain-associated protein       + More
Transcription-associated protein 1      
Uncharacterized PI3/PI4-kinase family protein C1F5.11c      
Probable transcription-associated protein 1      

Alternative Name

350/400 kDa PCAF-associated factor
STAF40
Tra1 homolog
dTRA1
p400 kDa component of SAGA

Location in the cell

Cytoplasmic   Reliability : 1.914

CDS

ATGATGGCAGCGATGGCTACAACGGGTCCAGGGGACCCGCACACGCAGATGAACACATATCGCAGCTATGTAACTATGTTGGCTGATCCCGGCGCTAAAGATGAAATCAAATTAAAAGCAGCCCAAGAACTTAGCGAAAATTTTGAGGTCATACTGAGTTCACCTCAGTATCCACAATTCTTAGACCATTCAATCAAAATATTTCTCAAAATATTACAAGATGGTGAGCCACATTTTATTGCTGAGTACAACATACAACAAGTTAGAAAACTTATTTTGGAAATGATACATCGCTTGCCAATCAGTGAGACTTTAAGACAATATGTGAAAAGCATTCTGATTTTGATGCTGAAGTTAATGGAGATAGAAAACGAGGAGAATGTTTTGGTGGCTTTGAAAATATTTATGGAGCTTCATAAGCAATACCGGCCTCCATACAGTACTGATGTTGATATACACAAATTTCTACAATGGGTAAAAGGAATTTACTCTGATTTGCCTAATCACCTACCGAAGATATTCGAACCAAAACCGACTCTTAGGGTGAAAGACTTGTCAGAAGTCAACATAGACCAACTCTTACAAGAAACATATACTACTACGCCTATTCACACTGAAAAGAAATTACTCGATGGAAGTGTAGTGACTTACAACCTTATACCAAGATCTGTACTTTCACTGAAGGTAATACAAGAGTTGCCAATAATAGTAGTTCTCATGTATCAACTCTACAAACAGAATGTTCATCAGGAAGTCAGTAACTTTATACCTCTCATAATGGAAACCATTACTCTACAACCATCACCAGCACATAGGAAGTCTGCCTCATTTAATAAAGAGGTATTTGTAGATTTTATGGGGGCACAAATTAAGACACTAGCATTTTTGGCGTATATTATAAGAATATATCAAGATACTATTGCAAATCATGCTAACCTCATGGTAAAAGGCATTATTGGCTTATTGACTTTATGCCCCCCAGAAGTGGCACATCTGAGAAAAGAGCTAGTGATTGCAACACGTCACATTCTTGCCACGGATCTGAGACTGAAATTTGTGCCCTATATGGAGCGACTCTTTGATGAAGATGTTTTATTAGGAGGAGGTTGGACTGTTCATGAATCTCTACGCCCACTAGCATATTCCACATTAGCTGACTTAGTACACCATGTACGGCAACATCTGCCATTGACCGATCTCGCGATTGCAGCACATTTATTTTCCAAGAATGTTCATGATGAGTCATTACCAACAAGTATCCAAACTATGTCATGCAAATTACTGCTAAATTTAGTAGATTGCATAAGGCAACGCTCTGAGGGTGAAGGTTCCACAACCACAGCAACTCAGCCTCAAGGGCGACATCTTCTCATGCGCATCTTGGAAGTCTTCGTATTGAAGTTCAAAACTATTTCAAAACTACAGCTACCTGCGCTTATGGCCAAATGTAAACCAGCTACACCGCCACAAAATTGCACTAACGGTGCAATTCCTGGCACGCCCACAACAGCGGGGGCTCCAACGAACACAACTACTGCTGAAGTAAAAGTTGAGGAGGAAAAGCCATCCCCAGATTTCCTTGATAATATTGCTAAATCTGAGGAAAGATCAAAAATTGGTTTTCCATCATCACAGATGAACAATTTAAACGTCGGAGACTATAGAACTTTAGTAAAAACTTTGGTTTGTGGTGTGAAGACTATAACTTGGGGTTGTGCTTCGTGTAAACAAACTAGTACGGGTGAAGGGTCGTCCACGGCAAATATAACAGGACAGAAGCAGTTCAGTGCACGAGAAACTTTAGTGTTCATCAGGCTCGTTAGGTGGGGCCTCCAGTCCCTCGACATATACACGCTGGCGGCGCCGCGCGCGCCCGCACAGCCGCCCGCGCAGCCGCACGTGCGCTCCAAGGAAGAGAAGGAAGTACTGGAGCACTTCAGTGGCGTGTTTTCAATGATGAACCCTCAAACGTTTCAAGAAATTTTCACGGCAACCATTTCACACATGGTCGAAAGAATCAACAAGAATACCACATTGCAGATCATAGCAAATACTTTTCTGTCAAATCCGGCCACGTCCCCGATCTTTGCAACGGTTCTCGTTGAATATCTACTGAAAAGAATGGAGGAGATGGGGACTAATGTAGAGAGATCTAATTTATATCTCAGATTATTTAAATTAGTATTTGGATCAGTTAGCCTGTTCCCAACGGAGAATGAGCAGATGCTGAGACCCCACTTACACAGCATCGTAAACAAGGCGATGGACTATGCGATGACGGCCAAAGAACCTTATAATTATTTCCTACTTTTGAGAGCCCTGTTCCGATCTATTGGCGGCGGGAGCCATGACTTGCTTTACCAAGAATTCTTACCCCTATTACCGAATTTACTTGAAGGCTTAAATCGCTTACAAAGTGGTCTGCACAAGCAACACATGAAAGATCTATTTGTAGAATTGTGTCTGACCGTACCCGTCCGATTGAGCAGTTTGTTACCATATTTACCAATGCTGATGGATCCGTTGGTTTCTGCTTTGAACGGTTCTCATACATTAATATCACAAGGTCTGCGCACTCTCGAACTTTGCGTAGACAATTTACAACCCGACTTTTTGTACGAGCACATTCAACCAGTTCGAGCGGACTTAATGCAAGCCTTATGGAGAACACTGCACAACAACGAAGTTGCAAGGATAGCGTTCAGAGTGCTAGGAAAGTTCGGTGGTGGGAACCGCAAAATGATGATTGAACCTCAACGGCTTGAGTACCGCGAGACCGACGTGCCGCCGCCCTCTGTGCAAGCGTATTTCCAAGATCAAGCGAAACCGATAGATTTTGAAGTCGACAAAGTAATCGAAACCGCTTTTTGTGCATTAAAATCAAGTACAACAGACCCATTCTACAGAAAACAGTGCTGGGAAGTACTACGATGCTATCTAGCTGCGTCGCTGAACCTAGATGACGATAAAGCAACTTTACAAAAGCTATTCAACCATCCAAGTTTCTTGGACGGTCGTATCCAAGTTCAAAACGGACCGTACTATAAGTGTAGCAATTCAATCGTCAGGAACACGCATCGCACTGCGTTAACAGGAATGTTCGTGGCGGCCGCTATCAAAGAGCTGCGACACCACGTCCTGCCGACCATGGTCTCGCTCGTCAGGCATTACACTATGGTAGCAATAGCACAAGAAGCGGGACCATTTGTCGGATCTAATGCACCTAAGGAAGGTCTCGATGCGTTAGTGTTGGTAGATGCCATCGCTGTCGTAATGGGTCACGAGGAAAAAGAACTTTGTAAACCAGGACATTTAGCTCTGCTACTAATGATCGAAACGGCTGCTACAGTACTGGGTACCAAAGAACGCGCGTGTCGCTTACCTCTAATGGAGTATCTCGCCGAACGTATGTCGGCTCTGTGCTACGAACGTGCCTGGTATGCTAAGTTTGGTGGCTGTATAGCAGTCAAGTTTATGGTCGAAAAGATGGCCCCAGAGTGGGTATACAAACACGTTTTCACATTCTTGAAAGCTGTTTTGTTTGTGATGATGGACTTAACCGGAGAAGTGTCTTCCGGAGCGATCGACATGGCCACAATGAACTTAGAGCGTCTTGTAAAAGTATGTGTTACTAGCCACGGAATACCGGGACAATCGGAGTCTGAAGGCGAAGTGGCTGCGGCAAGAGCCAGAGCCCTACACGATGTTTTGCAGGAACTCGTACTACAAGTCACAAGTCCGCATCTTCTTGTTCGACAGCAGGCGATGAAATCTCTGGAACTAATAGCCGAGTTACAAAAGAAGACTGTGACAGAAGTAATGGATCCGCACCGAGATGTACTCGCAGATATCATACCTCCCAAGAAGCATCTGTTGCGTCATCAGCCAGCGAACGCTCAAATGGGTTTGATGGATGGAACAACATTCTGTACAACATTGAAGCCTCGATTATTTACCATAGATCTTAACATTAACGAACATAAAGTATTCTTTCGTGAGTTGATATCTTTGTGTGAAGCTGAAGATTCGATGCTAGGGAAGCTACCTTGTTACAAAGGTGTCAACTTGGTGCCTCTACGCGCCTCTGCTTTGAGGGCTCTGGCGTCTTGTCACTACATGCAAGAGAAACACTGCAGAGAGAAAATATTCCAAGTACTTTATAAATCTTTAGAGAAGAACGATACGGAATTGCAACAAGCTGGCTTTGAATGTATGCAGAAGTTCTTATCCGGCTTTCAAATCGACATGGAGATGGTCCACCCGGTGATGCGGCCGCTGCTGCTGACCCTGGGCGACCACCGTCACCTCAGTGTGAACGGCGCAAAACGACTATCGTATTTGACGCAATTATTTCCCTCCACGTTCAGCGAGAAGCTCTGTGAGCAGCTTCTGCAGCTTCTGAAGAAGTTGCTGGATTATTCTATACAAACAAATAGGGGCGGAAATTTCTTGCAAAGTGTTTCGAAGAACATGGAGAACGAGCAAAAAATCTTGATTTTAATTGGAATATTTCATCAAATACCAGCAGCATCACCCCGCTTTATTGACGTTCTTTGTCGCCTTATATTTCACACCGAAAAGTCTCTGATGATTGAAGCTGGTTCGCCTTTTAGAGAGCCACTGGTCAAATTCCTTATGAGATACCCAAAAGAGACCCTGGATTTAGTGCTGGGCGACAATAATATAAAGGACCAGCAGTGGAGTCGATTCCTGGTCTTCCTTATCAGACATCCCGAGGCTGGTCCCGCGTACAGAGAGGCGCTACAGACTTCTAAAAAGCCTCGTCTAATGCAATTGTTAGCGTCCAACTCGACCGCGACAGCCGCCCAACCTCAGCCAGAAAAAGCTGAAATGCAATTCCAGGCCGTCAGGGCTATATCGTTGCTGATCAAATATGACGACCAGTGGCTGTCCACTCAGCATGACTTGATAGAATTACTGAAACGCATATGGTACAGCGACAAGTACCATGAAATTCATAAGAAAGTGGAAATTGTGGATTGCACTCATTGGAAAGAACCAAAACTGATTGTGAAGATTTTGTTGCACTATTTCTGTCATCATCCTAACAATATCGACCTCTTGTTTCAACTGCTGAGAGCGTTATGCGATCGTTTTGTGCCAGACTTCCAGTTCCTGCGAGACTTCCTGGAAAATACAGTAGCACAAAATTACACAATCGAATGGAAAAGGTCGGCGTTCTTTCGCTTCGTCGAACATTTCTCTAACGACGCAATGTCTCAGGAATTAAAGGCGAAAGTCTTGCAGATGATTCTGATTCCCTGTTTCGCTGTTAGCTTCGAGAAGGGGCAGAAAATAGTCGGAGGCCCGCCGGCCCCATATCAGGACAACCCCGACAATGTCGTCTCTGTGTTCATAAATAATGTCATAGATCCAGAAAATCCATTCGCTTGTTCGGACGCGGTTCGCATATCCCTGCTCCAGTTCGCATGCCTGTTGCTGGAGCAGGCGTCGGCTCACATCCACGACGCTAATAACAAGAAGCAAGGAAACAAACTCCGCAGGCTCATGACCTTCGCCTGGCCGTGCCTCCTCGGGAAGAACTACGTCGATCCAGCCACCAGATACCATGGCCATTTGTTATTGAGTCATATTATTGCGAAATTCGCAATACACAAAAGAATCGTTCTGCAAGTATTTCACAGTCTGCTAAAGGCCCACGCGGTGGAAGCGCGTTCTGTGGTGCGCCAAGCGCTAGAGATACTGACGCCGGCGATGCCGCAGCGCATGGAGGACGGCAACACGATGCTAACGCATTGGACCAAGAAGATTATTGTTGAGGATGGACATTCAGTGCAACAGCTCTTCCACATACTGCAGTTGGTCGTGAGACATTATAAGGTGTACTACCCGGTGCGGCACGCGCTGGTGGGACACATGGTGGGCGCCATGCAGCGGCTCGGCTTCTCTGCGACCGCCTCGCTGGAGCACCGCCGGCTCGCCGTGGACTTGGCCGAGGTGGTGCTCAAGTGGGACCTGCAGCGCATCCGGGACCACGCACTGCCCGACGACAACATCGTGGCGACATCTCCGGGCGGCGCCATGAAGCGCGTGTCGTCCGATGACGCGAGCTCGGAGGGTCGCAAGGCGTTGAACACGGGCTGGGCGAGCCCGCAGGCCAGCGCCTCCAGGCTCGAGCCCGACGCCGCCAAGCCGCTCGACAGACAACACGTAGATGTCGTTGTCAACCTGCTACTGCGACTGGCTTGCCAGGTGTGCCAAACGATGAACGAGGGTACCGTTTCCGGAAGCGGAGGTGCGACCGCAGGAGAGCAGCTATCGCGAAGATGCGTTCTTCTTCTTAAGACTGCTCTCAAACCCGACGTTTGGCCACACCTCTGCGAGCCTAAGCTTGCCTGGCTTGATAAAGTTTTCTCAAGTGCAGAGACAAACGCGGCATCATGCGCCAATGCCTGCACGGCGCTCGAGCTGCTGGTGTTCCTGCTGGGCGTGCTGCGTCGAGATCAGATCCTGGCGGCGCTGAAGCCGCTGCAGCGCGGGCTGGCCGCCTGCGTCGCGTCCACTAATGCCAAAATCGTGCGACTGACGCACAACTTGCTCGCCAAGCTTACCGCCATCTTCCCTACGGAGCCCACGGGGGCCGCGCAAGCTTCTAAGTACGAGGAGCTCGAAACACTATACGCGTGCGTGAGCAAGTACGCGTTCGAGGGTCTGGCGGCGTACGAGAAGACGGCGGGCAGCGGCACGGGCGGCACGTCGGGCGCGGGCGCGCTGCTGGGGCCGCTCATGATGCTGAAGGCGTGCTGCTCCTCCAGCCCCGCCTACATCGACCGCCTGCTGCTCCCGCTCATGCGCGTCCTGCAGCGCATGGCTAGGGACCACGTCGCCACCAACCCCGATGCAGCCATATCCGATTTGTTGATATTGGCCTTAGACTTGCTAAAGGCTCGCGTTTCCGTGATGCCGGGCGATACGAAAAAAACCTTCATAGGAACTGTTCTAGTTGGTCTTATCGAAAAGACTACAGATTCTAAGGTAATGAAAGCGATCATTCGTATGGTTGAGGAGTGGGTGATGCACCGCGGCGCGACCACTAGCAGCGGGGCCGTACCTTCCCTGCGCGAAAAGTCAATACTGCTCGTGAAACTAATGCAATATGTCGAGAAACGTTTCCCTGACGACCTCGAGCTCAATGCTCAATTTTTAGAACTGATCAACTACGTGTATCGGGATGAACAGCTGAAGGTGACGGAACTATCCATGAAGTTGGAGCCCGCTTTCCTGGCGGGTCTCCGTTGCCCGCAGCCACAGATCCGCGCCAAGTTCTTTGAGGTGTACGACCAGAGCGTGCGGCGGCGCGTGTTCGACCGCCTGCTGTACGTCGTGTGCTCGCAGAACTGGGAGCACATAGGACAACACTTCTGGATTAAACAGTGCCTCGAACTGCTATTGGTCACCTGTGCGCCCAGCACTCAAATTCGTCTATCGAATCCAAAATACTTGTTGCCGAGCATATCATCGGTCATCAATCAAGCGGATAGCGAGGACCGAAAGTCATTCATCATCTTTAGCAGCGTTAAAGAAGAATCATCCGACGGATTTAGCGATTCCCTCGATCCCGACAAGGAGGACGTGCTGGATATGGATTTAGACGCGAGTTCCACTCATAAAGAAGATTTCACTAAGAATGTTCCAAACAGACAGCGATCGCTAAACCAGATAGTGGCAAAGCAATCGGAGTTCCTGGAACTGGCGCGTCGCGTCCGCGCCGAGCAGCTGCTGGCGGCCTCCGCGCAGCTCTGCCACATGGACGACACGCTCGCGCACCACGTGTGGCTCGCCCTGCTGCCCGCGCTCTGGGCCACGCTCGACGAACGACAGCTCACGACGCTGATCAACGAGGTTGTTCCTTTCATCATATCTGGCGTGCACGTGATTCAACGCGATCAGCCCGTCAGCGCCCTCAACACGTTCATAGAATCCCTCGCTCGATGTAATCCTCCCATCAGCATCAAACCCCCTATGATGAAGTATTTGGGAAAAACGCACAACCTCTGGCATCGTATGACACTGAATCTCGAGCAGATGGCCATCGAGCAGGCCGGCGGGCGGGTTCAAAGGGACCAAGCAGAAATATATGATTACGACGTAGAAGTGACGACGCCGACTGAAATTTTAGATTCACTCAGCGATATGTATGAGTTATTACAAGAAGAGGATATGTGGTCTGGTCTTTGGCAGAAGCATTCAAGGTACCGCGAAACTAATATCGCAATCGCCTATGAACAACAAGGCTTCTTCGAACAAGCTCAAGCTGCATACGACGTCGCTATGGCCAAGCTGAAACAAGACTATGCGACAAACCCATCCTCTTACAGCATGCACAAAGAGTGCACTATTTGGACCCAACATTGGCTGAAGTGTGCCAAAGAGTTAAACCAATGGGACTCTTTACTTGAGTTAGGACTAAGCAGAAGCGGTCGCGATCCATTCTTGATTCTGGAAAGTTCATGGCGTAACCCTAACTGGACTACAATGAAAGAAGCTTTAGCTGAAGTCGAATACAATTGCCCTAAGGAATTGGCGTGGGTAGTAAACCTGTACCGCGGGTACCTGTGCATATGCGCGGGCGGCGCCGAGCAGCTGGGCGGCGTGGAGCGGCACGCGGAGGCGGCGGCGGCGCAGTGTCTGCGCGAGTGGCGCCGCCTGCCGCGCCTCGTGTCGCACGCGCACCTGCCGCTGCTCCGCGCCGCGCAGCAGCTCATGGAGCTCAGCGAGGCCGCGCAGATACACACCGGCTTGGTGCACAGCCGGCCGACGTCCCTGCACGACATGAAGGCGATAGTGAAGACGTGGCGCAACCGGCTGCCCGTGGTGGCGGACCCGCTGTCGCACTGGGGCGCCATCTTCACGTGGCGGCAGCACCACTACCAGTTCATCGCGTCGCACTACGACTCGCAGCCGGACCACGCCTCCAATCACAGCATGCTTGGCGTCCATGCCAGCGCTCAGGCCATTATTCACTTTGCGAAAATAGCTAGAAAACATAACCTATCTGGAGTGTGTCTGGATTCCCTACACAGAATTTACACAATACCGAGCGTACCGATCGTTGACTGCTTCCAAAAGATAAGGCAACAAGTCAAATGTCACATTCAGATGTCATGGACCGAGGGCAAAGATGAGCTCCAGGAAGGATTGGATATGATCGAATCAACTAACTTCAAATATTTCACTAAAGAAATGACGGCCGAGTTTTATGCTTTCAAAGGATTACTTCTAGCGCAGCTGGGCCGCTCCGACGACGCGAACAAAGCGTTCGCCGCCGCGGTGCAGCTGCACGACACGCTCGTGAAGGCCTGGGCGCTGTGGGGCGACTACTTGGAACAGATATTCATCCGCGACCCGCGACAGATCTCCGTAGGCGTCTCCGCCATGACTTGCTTCCTGCACGCGTGTCGTCATCAAAATGAATCCAAGTCTAGAAAATATTGTGCCAAGGTGTTATGGATGCTGAGTTTCGACGACGAAAAGAATAGTCTCGCAGAAGCATTAGATAAATACTCAGTCGGAGTCCCGCCTGTGCAGTGGCTGCCCTGGATACCGCAGCTGCTGGCCTGCCTCGTGCAGTACGACGGCAATGTTATACTCAACCTGCTCAGTCATGTTGGTCGATTATATCCACAAGCCGTATACTTCCCAATCCGAACTCTGTACTTAACGTTGAAGATTGAGCAGCGAGAGCGTCACAAAACAGCCGAGAGCATTGCACATTTACCGCATCAACCTACCACGTCTGGAAGCAGCAAGGCCAACGAGGGCGCCAGCACGTCCAGCGGCGAGGCGGGGCCCATCCGCGCCACGCTGCCCATGTGGCGCTGCTCGAAGATCATGCAGCTGCAGCGTGAAATACATCCCACTGTTCTCTCCTCCCTCGAGGGAATCGTCGACCAGATGGTATGGTTCCGCGAGAACTGGTACGAGGAGGTGCTGAGGCAGCTGCGCGCGGGGCTGGCCAAGTGCCTGGTGGTGTCCTTCCACCACCGTGCCGCCGTCGCAGACGCCACCGTCACGCCACACACGCTCAACTTCATCAAGAAGGTCGTCTCTACCTTCGGCATCGGCATCGGCATCACTGCATCGGAGAGTCTCGCCCGTCGCGCCCAGGCCACCGTGCAAGATCCCGTGTTCCAGAAAATGAAAACTCAGTTCACTGCCGACTTTGATTTCTCGCAACCGAACGCTATGAAGCTGCAGAATCTCATACAGAAGCTGAGGAAGTGGGTGAAGATTCTCGAAGCCAAAACTAAAGTCTTACCTAAGTCATTCCTCATCGAGGAAAAATGCAGGTTCCTATCGAACTTCAGCCTTAAAACGGCCGAAGTGGAACTGCCCGGCGAGTTCCTGCTGCCGAAGCACACGCACTACCACGTCCGCATCGCGCGCTTCATGCCGCGCGTCGAGATCGTGCAGAAGCACAACACGTCGGCGCGCCGCCTGTACATTCGCGGCCACAACGGGAAGATCTACCCGTACCTCGTCGTCAACGACTCCGGACTGGGCGACGCCAGGCGAGAGGAGCGCGTCCTGCAGCTGCTCAGAATGCTGAATCACTACTTGGGGAAACAGAAGGAGACCTCCCGCCGCTTCCTCCACTTCACCGTGCCCCGCGTCGTGTCCGTCTCGCCACAGATGCGTCTAGTCGAAGACAATCCTAGTTCGATATCTTTATTGGATATTTACAGGACGGAGTGTGCGAACAGAGGTGTAGAGTACGACGCACCCGTGGCCCGGTACTACGAGCGGCTGGCGGCGGTGCAGGCGCGCGGCTCGCAGGCCTCCCATCAAGTGCTCAGAGACATATTACGAGAGGTCCAAGCCACGATGGTGCCGAAGGGAATGCTCCGCGAGTGGGCGGGGGCGACGTTCGCCGCGCCCACCGACTACTGGACGTTCCGCAAGATGCTGACCCTGCAGCTGTCGCTGTCCAGCTTCGCGGAGTACGTGCTGCACCTCACGCGCCTCAACCCCGACATGATGTACGTGCACCAGGACTCGGGACTCTTGAACGTTTCCTACTTCAAGTTTGACGTCGACGACACAACAGGTGAATTAGACGGGAACAGGCCCGTTCCGTTCCGCCTCACGCCCAACATAGCCGAGCTGTTGACGAACATCGGCATCACGGGCCCTCTCACCGCGTCGTCTATAGCCATCGCAAGATGTCTCGTGACACCTAATTTCAAGATTCAATCCATATTACGCACGATACTTCGCGACGAAATGGTGACCGGCTATAGAAAACGATTGGAAGATAAATCCGGTATGCCATCAGCGGGAACGTCGACGGAGAACAAACCAGTCGAAATGGATAACGAAACCATAATAAATATGGTGAACAAGGCCGTGACGGTCATCATGAACCGACTCAACTCTCTGGCGTCGTTCGACGGACCCGACAGCAAGGTGGCAACCCTAGTCGCGGCCGCCAACAGCCACGACAACCTTTGCCGAATGGATCCCGCTTGGCATCCGTGGCTCTAA

Protein

MMAAMATTGPGDPHTQMNTYRSYVTMLADPGAKDEIKLKAAQELSENFEVILSSPQYPQFLDHSIKIFLKILQDGEPHFIAEYNIQQVRKLILEMIHRLPISETLRQYVKSILILMLKLMEIENEENVLVALKIFMELHKQYRPPYSTDVDIHKFLQWVKGIYSDLPNHLPKIFEPKPTLRVKDLSEVNIDQLLQETYTTTPIHTEKKLLDGSVVTYNLIPRSVLSLKVIQELPIIVVLMYQLYKQNVHQEVSNFIPLIMETITLQPSPAHRKSASFNKEVFVDFMGAQIKTLAFLAYIIRIYQDTIANHANLMVKGIIGLLTLCPPEVAHLRKELVIATRHILATDLRLKFVPYMERLFDEDVLLGGGWTVHESLRPLAYSTLADLVHHVRQHLPLTDLAIAAHLFSKNVHDESLPTSIQTMSCKLLLNLVDCIRQRSEGEGSTTTATQPQGRHLLMRILEVFVLKFKTISKLQLPALMAKCKPATPPQNCTNGAIPGTPTTAGAPTNTTTAEVKVEEEKPSPDFLDNIAKSEERSKIGFPSSQMNNLNVGDYRTLVKTLVCGVKTITWGCASCKQTSTGEGSSTANITGQKQFSARETLVFIRLVRWGLQSLDIYTLAAPRAPAQPPAQPHVRSKEEKEVLEHFSGVFSMMNPQTFQEIFTATISHMVERINKNTTLQIIANTFLSNPATSPIFATVLVEYLLKRMEEMGTNVERSNLYLRLFKLVFGSVSLFPTENEQMLRPHLHSIVNKAMDYAMTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLEGLNRLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSHTLISQGLRTLELCVDNLQPDFLYEHIQPVRADLMQALWRTLHNNEVARIAFRVLGKFGGGNRKMMIEPQRLEYRETDVPPPSVQAYFQDQAKPIDFEVDKVIETAFCALKSSTTDPFYRKQCWEVLRCYLAASLNLDDDKATLQKLFNHPSFLDGRIQVQNGPYYKCSNSIVRNTHRTALTGMFVAAAIKELRHHVLPTMVSLVRHYTMVAIAQEAGPFVGSNAPKEGLDALVLVDAIAVVMGHEEKELCKPGHLALLLMIETAATVLGTKERACRLPLMEYLAERMSALCYERAWYAKFGGCIAVKFMVEKMAPEWVYKHVFTFLKAVLFVMMDLTGEVSSGAIDMATMNLERLVKVCVTSHGIPGQSESEGEVAAARARALHDVLQELVLQVTSPHLLVRQQAMKSLELIAELQKKTVTEVMDPHRDVLADIIPPKKHLLRHQPANAQMGLMDGTTFCTTLKPRLFTIDLNINEHKVFFRELISLCEAEDSMLGKLPCYKGVNLVPLRASALRALASCHYMQEKHCREKIFQVLYKSLEKNDTELQQAGFECMQKFLSGFQIDMEMVHPVMRPLLLTLGDHRHLSVNGAKRLSYLTQLFPSTFSEKLCEQLLQLLKKLLDYSIQTNRGGNFLQSVSKNMENEQKILILIGIFHQIPAASPRFIDVLCRLIFHTEKSLMIEAGSPFREPLVKFLMRYPKETLDLVLGDNNIKDQQWSRFLVFLIRHPEAGPAYREALQTSKKPRLMQLLASNSTATAAQPQPEKAEMQFQAVRAISLLIKYDDQWLSTQHDLIELLKRIWYSDKYHEIHKKVEIVDCTHWKEPKLIVKILLHYFCHHPNNIDLLFQLLRALCDRFVPDFQFLRDFLENTVAQNYTIEWKRSAFFRFVEHFSNDAMSQELKAKVLQMILIPCFAVSFEKGQKIVGGPPAPYQDNPDNVVSVFINNVIDPENPFACSDAVRISLLQFACLLLEQASAHIHDANNKKQGNKLRRLMTFAWPCLLGKNYVDPATRYHGHLLLSHIIAKFAIHKRIVLQVFHSLLKAHAVEARSVVRQALEILTPAMPQRMEDGNTMLTHWTKKIIVEDGHSVQQLFHILQLVVRHYKVYYPVRHALVGHMVGAMQRLGFSATASLEHRRLAVDLAEVVLKWDLQRIRDHALPDDNIVATSPGGAMKRVSSDDASSEGRKALNTGWASPQASASRLEPDAAKPLDRQHVDVVVNLLLRLACQVCQTMNEGTVSGSGGATAGEQLSRRCVLLLKTALKPDVWPHLCEPKLAWLDKVFSSAETNAASCANACTALELLVFLLGVLRRDQILAALKPLQRGLAACVASTNAKIVRLTHNLLAKLTAIFPTEPTGAAQASKYEELETLYACVSKYAFEGLAAYEKTAGSGTGGTSGAGALLGPLMMLKACCSSSPAYIDRLLLPLMRVLQRMARDHVATNPDAAISDLLILALDLLKARVSVMPGDTKKTFIGTVLVGLIEKTTDSKVMKAIIRMVEEWVMHRGATTSSGAVPSLREKSILLVKLMQYVEKRFPDDLELNAQFLELINYVYRDEQLKVTELSMKLEPAFLAGLRCPQPQIRAKFFEVYDQSVRRRVFDRLLYVVCSQNWEHIGQHFWIKQCLELLLVTCAPSTQIRLSNPKYLLPSISSVINQADSEDRKSFIIFSSVKEESSDGFSDSLDPDKEDVLDMDLDASSTHKEDFTKNVPNRQRSLNQIVAKQSEFLELARRVRAEQLLAASAQLCHMDDTLAHHVWLALLPALWATLDERQLTTLINEVVPFIISGVHVIQRDQPVSALNTFIESLARCNPPISIKPPMMKYLGKTHNLWHRMTLNLEQMAIEQAGGRVQRDQAEIYDYDVEVTTPTEILDSLSDMYELLQEEDMWSGLWQKHSRYRETNIAIAYEQQGFFEQAQAAYDVAMAKLKQDYATNPSSYSMHKECTIWTQHWLKCAKELNQWDSLLELGLSRSGRDPFLILESSWRNPNWTTMKEALAEVEYNCPKELAWVVNLYRGYLCICAGGAEQLGGVERHAEAAAAQCLREWRRLPRLVSHAHLPLLRAAQQLMELSEAAQIHTGLVHSRPTSLHDMKAIVKTWRNRLPVVADPLSHWGAIFTWRQHHYQFIASHYDSQPDHASNHSMLGVHASAQAIIHFAKIARKHNLSGVCLDSLHRIYTIPSVPIVDCFQKIRQQVKCHIQMSWTEGKDELQEGLDMIESTNFKYFTKEMTAEFYAFKGLLLAQLGRSDDANKAFAAAVQLHDTLVKAWALWGDYLEQIFIRDPRQISVGVSAMTCFLHACRHQNESKSRKYCAKVLWMLSFDDEKNSLAEALDKYSVGVPPVQWLPWIPQLLACLVQYDGNVILNLLSHVGRLYPQAVYFPIRTLYLTLKIEQRERHKTAESIAHLPHQPTTSGSSKANEGASTSSGEAGPIRATLPMWRCSKIMQLQREIHPTVLSSLEGIVDQMVWFRENWYEEVLRQLRAGLAKCLVVSFHHRAAVADATVTPHTLNFIKKVVSTFGIGIGITASESLARRAQATVQDPVFQKMKTQFTADFDFSQPNAMKLQNLIQKLRKWVKILEAKTKVLPKSFLIEEKCRFLSNFSLKTAEVELPGEFLLPKHTHYHVRIARFMPRVEIVQKHNTSARRLYIRGHNGKIYPYLVVNDSGLGDARREERVLQLLRMLNHYLGKQKETSRRFLHFTVPRVVSVSPQMRLVEDNPSSISLLDIYRTECANRGVEYDAPVARYYERLAAVQARGSQASHQVLRDILREVQATMVPKGMLREWAGATFAAPTDYWTFRKMLTLQLSLSSFAEYVLHLTRLNPDMMYVHQDSGLLNVSYFKFDVDDTTGELDGNRPVPFRLTPNIAELLTNIGITGPLTASSIAIARCLVTPNFKIQSILRTILRDEMVTGYRKRLEDKSGMPSAGTSTENKPVEMDNETIINMVNKAVTVIMNRLNSLASFDGPDSKVATLVAAANSHDNLCRMDPAWHPWL

Description

Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Part of the Tip60 chromatin-remodeling complex which is involved in DNA repair (PubMed:15528408). Upon induction of DNA double-strand breaks, this complex acetylates phosphorylated H2AV in nucleosomes and exchanges it with unmodified H2AV (PubMed:15528408). During wing development, required for activity of Notch and its coactivator mam (PubMed:16508010). Function in promoting mam function is likely to involve both the Tip60 and SAGA complexes (PubMed:16508010).
Influences germ cell fate in hermaphrodites (PubMed:24098152). Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development (PubMed:15068795).
Essential component of histone acetyltransferase (HAT) complexes, which serves as a target for activators during recruitment of HAT complexes. Essential for vegetative growth. Functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus.
Essential component of histone acetyltransferase (HAT) complexes, which serves as a target for activators during recruitment of HAT complexes. Essential for vegetative growth. Functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation (By similarity).
Influences germ cell fate in hermaphrodites (PubMed:24098152). Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (PubMed:24098152). Required for spermatogenesis and embryonic development (PubMed:24098152). Acts with tra-2 to promote expression of fog-3 and control male tail development (PubMed:24098152). Involved in the negative regulation of vulval development (By similarity).

Subunit

Interacts with MYC, E2F1 and E2F4 transcription factors. Interacts directly with p53/TP53. Interacts with GCN5L2. Component of various HAT complexes. Component of the PCAF complex, at least composed of TADA2L/ADA2, SUPT3H, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H/SPT3, TAF2/TAFII150, TAF4/TAFII135, TAF5/TAFII100, GCN5L2/GCN5, TAF10 and TRRAP. Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. Component of the STAGA complex, at least composed of SUPT3H, GCN5L2, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22. Component of the BAF53 complex, at least composed of BAF53A, RUVBL1, SMARCA4/BRG1, and TRRAP, which preferentially acetylates histone H4 (and H2A) within nucleosomes. Interacts with NPAT. Interaction with TELO2 AND TTI1. Component of a SWR1-like complex.
Component of the Tip60 chromatin-remodeling complex which contains the catalytic subunit Tip60 and the subunits Domino, Tra1, Brd8, E(Pc), DMAP1, Pontin, Reptin, Ing3, Act87E, BAP55, Mrg15, MrgBP, Gas41 and YL-1 (PubMed:15528408). Probable component of some SAGA complex (PubMed:12697829). Interacts with Spt3, Gcn5, Ada3 and Ada2b (PubMed:12697829).
Component of the 1.8 MDa SAGA complex, which consists of at least of TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1. TAF5, TAF6, TAF9, TAF19, TAF12 and ADA1 seem to be present in 2 copies. SAGA is built of 5 distinct domains with specialized functions. Domain I (containing TRA1) probably represents the activator interaction surface. Domain II (containing TAF5 and TAF6, and probably TAF9 and TAF10), domain III (containing GCN5, TAF10, SPT7, TAF5 and ADA1, and probably ADA2, ADA3 and TAF12), and domain IV (containing HFI1/ADA1 and TAF6, and probably TAF9) are believed to play primarily an architectural role. Domain III also harbors the HAT activity. Domain V (containing SPT3 and SPT20, and probably SPT8) represents the TBP-interacting module, which may be associated transiently with SAGA. Component of the SALSA complex, which consists of at least TRA1, SPT7 (C-terminal truncated form), TAF5, ADA3, SPT20, TAF12, TAF6, HFI1, GCN5, ADA2 and SPT3. Component of the SLIK complex, which consists of at least TRA1, CHD1, SPT7,TAF5, ADA3, SPT20, RTG2, TAF12, TAF6, HFI1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10 and TAF9. Also identified in the NuA4 complex with ESA1. Identified in the Ada.spt complex with ADA3 and SPT7.
Component of the SAGA complex.

Miscellaneous

Although strongly related to the PI3/PI4-kinase family, it lacks the typical motifs that constitute the catalytic site of PI3/PI4-kinase proteins, suggesting that it probably lacks such activity.
Although strongly related to the PI3/PI4-kinase family, it lacks the typical motifs that constitute the catalytic site of PI3/PI4-kinase proteins, suggesting that it may lack such activity.

Similarity

Belongs to the PI3/PI4-kinase family. TRA1 subfamily.
Belongs to the PI3/PI4-kinase family.

Keywords

Acetylation   Activator   Alternative splicing   Chromatin regulator   Complete proteome   Direct protein sequencing   Isopeptide bond   Nucleus   Phosphoprotein   Polymorphism   Reference proteome   Transcription   Transcription regulation   Ubl conjugation   Chromosome   Cytoplasm   Repeat   Developmental protein   Differentiation   Spermatogenesis   TPR repeat   3D-structure   Kinase   Transferase   Coiled coil  

Feature

chain  Transformation/transcription domain-associated protein
splice variant  In isoform 2.
sequence variant  Found in a cutaneous malignant melanoma sample; somatic mutation; induces cell transformation and confers resistance to apoptosis; dbSNP:rs147405090.

Uniprot

Q9Y4A5.3   Q8I8U7.4   G5EEV2.1   P38811.1   Q10064.1   Q9HFE8.1   + More
A8WTE8.2   Q54T85.2  

EC Number

2.7.1.-

Pubmed

9708738    9885574    12853948    12690205    11564863    10373431    + More
10966108    10611234    11418595    11445536    12138177    11839798    12743606    12660246    14966270    18206972    18691976    17967892    18669648    19608861    20427287    20068231    21269460    21499247    22223895    23186163    24275569    24463511    28112733    17344846    12697829    16508010    10731132    12537572    12537569    15528408    15068795    9851916    24098152    8091229    24374639    9885573    9756893    10487762    10026213    11423663    12446794    12186975    14690591    15647753    18407956    19779198    22814378    15260971    11859360    14624247    15875012    16596165   

EMBL

AF076974    AF110377    AC004893    AC004991    CH471091    CH236956    + More
AY142217    AE013599    AY094769    DQ352451    AY551966    Z69902    AAS65430.1    U00060    BK006934    CU329670    CU329671    HE601438    CAP23759.2    AAFI02000043   

Proteomes

UP000005640    UP000000803    UP000001940    UP000002311    UP000002485    UP000008549    + More
UP000002195   

PRIDE

Q9Y4A5    Q8I8U7    P38811    Q10064    Q9HFE8    Q54T85    + More

Pfam

PF02259   FAT        + More
PF00454   PI3_PI4_kinase
PF02260   FATC

Interpro

IPR033317   TRA1/TRRAP        + More
IPR016024   ARM-type_fold       
IPR003151   PIK-rel_kinase_FAT       
IPR014009   PIK_FAT       
IPR011009   Kinase-like_dom_sf       
IPR000403   PI3/4_kinase_cat_dom       
IPR003152   FATC_dom       

SUPFAM

SSF56112   SSF56112        + More
SSF48371   SSF48371       

ProteinModelPortal

Q9Y4A5.3   Q8I8U7.4   G5EEV2.1   P38811.1   Q10064.1   Q9HFE8.1   + More
A8WTE8.2   Q54T85.2  

PDB

5OEJ     E-value=0,     Score=2335

KEGG

101740829    K08874 transformation/transcription domain-associated protein | (RefSeq) transformation/transcriptio

GO

GO:0000124   GO:0043968   GO:0006281   GO:1904837   GO:0003712   GO:0043967   GO:0016579   GO:0005634   GO:0000812   GO:0030914   GO:0035267   GO:0033276   GO:0005794   GO:0016573   GO:0006355   GO:0016578   GO:0005654   GO:0000125   GO:0005700   GO:0000281   GO:0005703   GO:0043966   GO:0006351   GO:0005737   GO:0000123   GO:0035222   GO:0043486   GO:0007275   GO:0007283   GO:0000003   GO:0040027   GO:0000793   GO:0040010   GO:0030154   GO:0046695   GO:0070209   GO:0045944   GO:0016301   GO:0010674   GO:0006357   GO:0006338   GO:1903508   GO:0004672   GO:0004402   GO:0006468   GO:0005524   GO:0005515   GO:0005488   GO:0046872   GO:0003824   GO:0006810   GO:0006397   GO:0004651  

PANTHER

PTHR11139:SF1  

Subcellular location

Nucleus  
Cytoplasm  
Chromosome  

Length:

3841

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.756680000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00467

outside

1  -  3841

 

 

Pi

207.269314

Theta

19.648873

Tajima's D

0.317948

CLR

0.239644

CSRT

0.467026648667567

Interpretation

Uncertain