Gene

KWMTBOMO01813

Pre Gene Modal

BGIBMGA006164

Annotation

proline_transporter_[Danaus_plexippus]

Location

Bomo_Chr4(+):5482832-5516645      View in EpiBrowser

Full name

Transporter      

Location in the cell

PlasmaMembrane   Reliability : 4.923

CDS

ATGGCAAGGGTCCAGCCGGAACGTTGGGCAAATCAAACTGAATATTTGCTATCGTGTCTCGGTTATGCTGTCGGCATCGGAAACTTGTGGCGATTTCCATATTTATGCTACCGTAATGGAGGAGGAGCATTCCTCATTCCGTACTTTTTAACTTTGATTATCTGCGGGATTCCCCTGGTCTATTTGGAAACGACATTGGGTCAATTCGCCAGTGCCGGATGCATTTCTGTCTTTAATATAAACCCTCTTTTCAAAGGTGCGGGTTACGCTGTTATAGTTCTAAACGTAATAGCAGTTATATATTTTTCTGCCATAATGTCGTATCCGGTACTGTACATCTATCATTCTTTGGGTTCGCCGTTACCGTGGCAAACCTGTGGAAACCCTTGGAACACCGATAAATGTACTGAGATAACAGGAAATTCAAGCTTTTTTTTGTCAAACGGCACGATCACGACGCCAGAAGACGAATTTTTTCACTTACGCCTCCTGCGGGTTTCTTCTGGTATCAGTGAAATAGGTAGTATAGTTTGGCCCGTGTTTTGGTGCAACGTGATATGCTGGATCATCATATACTTGTGCATTTGTAACGGAGTCAAAAGCGTCGGAAAGATAGTTTACTTTACGGTTGTATTCCCATATGTGGTTCTGTGCGCTTTGTTCGTTCGCGGCGTCACGTTACCTGGAGCTGGAAAAGGAATTCTATTCTACATTTTACCCGATTGGAAACAATTGATGAAGCCAAAAGTGTGGGTAGACGCGGCTACGCAGATTTTTTTTTCGCTTGGTCCCGGCTGGGGCGGCCTCGTCAGCATGGCCAGCTACAACAAGTTTCACTACAAAAATCTACGATCTTCGATCATAATACCGTTGGTAAACAGCGGCACCAGTGTGTGGGCTGGTTTTGTCGTATTTTCCGTACTAGGATTTGCATCAGAAAGAGCGAACGTCCCAGTAGGACAAGTGGCGACGGCCGGTCCTGGACTAGCCTTTGTCACATATCCGGCAACAGTTACTATGATGCCGGCACCAAATTTCTGGGCCGTCACATTTTTTGTAATGCTGTTTTTCCTTGGAATTGATACTATGTTCGTCACAATAGAAGCAGTGATCACAGGTTTAATTGATGAGTTCCCGAGATTACGTACGCGAAAAAGATTAATCACTTTGTTGACTTGCCTGGCACTTTTCGGTTTCTCGATCATCTGCAATACAGAGGGTGGCCTTCACGTGATGGAACTATTAGACGCACATGTAGCGATTACTTGCGTGCCCATAGTCTGCGCACTGGAGATCATAGCGGCGGTATATACGTATGGACCACGGGAACTGAGCACGGACGTAATGTTCATGACAGGACAACCGTTGGCGAGAATATGGCTGGTGCTGTGGAGATACGTGCTACCCTTTATTTTACTAACTATCACAGTGTACGCTCTGAAAGACGCAACGGGAATGGCCGGGTGGTGTGTAGCTTTCGTTTCAGTCTTGTGCATTCCGATACATGTAGTGAGACAATTACTCCGATCCAGGGGGTCCGTATTAGATGTTGAAGGAGAGGATGAAACAGGTGAAGGCGAAATGAGCCGTAAAAAAATGAAAAGATTTCAACTGCCCAATTTGCCTCGCTGGTGGCAGGCAAAAGTGATACAATATGCCTTTGCCCACCCGCACGTCCGTGCGCGGCTGGAGAAGCACATGGGATCAAACCTGGTGCGGCTCACGGACAAGAACTACATGACCGAATTGGAAGAAAGAATTAGAGCTGTCAACGAAGAAAATTTGAACAAAAGAATCTCTAGCAGAGTGCTTGATGAGATGGAAAGACTGAAAAGATTGATCCTTGTTGGAAAAACCCCGCTAAAGGAGTGTCCTCCTGAACTTTTCCACCACCCAGTATTTGTGTTCTGGAGAATGGTTAACAGGGAAGTTGCAAGAGCATCAAAAAAACGTGCCGATGCCTATTACAGGAAACTGAAAGCTTCCCAGAAATTCGATCAATCGATGGATGAGGAAGATGCCGGCGAGGAAGCTGAAGAGGAATGTGAACAAATGACTGCCGAACAGCTACTGGCTAAATGTCGTGAAGAAATAGAAGAACAAAAACAGTTAGACATAGAAAAGGGCGTACGATTTACTGACGAACAATTCGCACTCATGAAATATGAAACTAACGACGTTAAGACATTGAAAAATTTAACGACCGTCGATGAGCTTTATGCGTTGGCTGACAAAATTATTGGATCGAAACGTCTTTGA

Protein

MARVQPERWANQTEYLLSCLGYAVGIGNLWRFPYLCYRNGGGAFLIPYFLTLIICGIPLVYLETTLGQFASAGCISVFNINPLFKGAGYAVIVLNVIAVIYFSAIMSYPVLYIYHSLGSPLPWQTCGNPWNTDKCTEITGNSSFFLSNGTITTPEDEFFHLRLLRVSSGISEIGSIVWPVFWCNVICWIIIYLCICNGVKSVGKIVYFTVVFPYVVLCALFVRGVTLPGAGKGILFYILPDWKQLMKPKVWVDAATQIFFSLGPGWGGLVSMASYNKFHYKNLRSSIIIPLVNSGTSVWAGFVVFSVLGFASERANVPVGQVATAGPGLAFVTYPATVTMMPAPNFWAVTFFVMLFFLGIDTMFVTIEAVITGLIDEFPRLRTRKRLITLLTCLALFGFSIICNTEGGLHVMELLDAHVAITCVPIVCALEIIAAVYTYGPRELSTDVMFMTGQPLARIWLVLWRYVLPFILLTITVYALKDATGMAGWCVAFVSVLCIPIHVVRQLLRSRGSVLDVEGEDETGEGEMSRKKMKRFQLPNLPRWWQAKVIQYAFAHPHVRARLEKHMGSNLVRLTDKNYMTELEERIRAVNEENLNKRISSRVLDEMERLKRLILVGKTPLKECPPELFHHPVFVFWRMVNREVARASKKRADAYYRKLKASQKFDQSMDEEDAGEEAEEECEQMTAEQLLAKCREEIEEQKQLDIEKGVRFTDEQFALMKYETNDVKTLKNLTTVDELYALADKIIGSKRL

Similarity

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.

Uniprot

Q17IX2   B0W8R8   A0A182L090   A0A182RRM3   A0A2J7RFZ9   A0A2J7RFZ4   + More
A0A084W1W0   A0A182WHF4   A0A182KFV4   A0A182PWR0   A0A1I8NA66   T1PIK8   A0A182IBZ0   A0A182Y5H4   A0A182F2C6   A0A182QMM0   A0A182NUT4   K7IUT0   A0A1I8NVU3   A0A1S4GYD1   A0A2P8Z9Q9   Q7Q4L1   A0A0C9QRT5   A0A182X136   A0A1Y1MTC4   A0A182TXD0   A0A336LY90   K1PKZ3   H3A4J1   A0A2D4FQ05   U3ET06   A0A2D4FPZ8   A0A0B8RWB7   G1KQ50   A0A3P8XZP8   A0A1S3KTT1   A0A1S3KSY9   A0A1W7RAG3   A0A0F7Z8A6   V4BY13   A0A1L8GM87   B7ZSD9   A0A1L8GFQ3   H3CR97   Q4SNP9   H3C4F5   A0A146ZRR0   G3PN90   A0A3P8X1L5   A0A3P8X215   A0A3Q0DVD1   A0A2Y9IV28   A0A1U7TJN4  

Pubmed

17510324    20966253    24438588    25315136    25244985    20075255    + More
12364791    29403074    28004739    22992520    9215903    23915248    25476704    25069045    23254933    27762356    15496914    24487278   

EMBL

CH477236    EAT46621.1    DS231860    EDS39297.1    NEVH01004407    PNF39766.1    + More
PNF39765.1    ATLV01019468    KE525272    KFB44204.1    KA648637    AFP63266.1    APCN01000762    AXCN02000743    AAZX01005919    AAAB01008964    PYGN01000135    PSN53224.1    EAA12299.4    GBYB01003342    JAG73109.1    GEZM01026075    JAV87256.1    UFQT01000295    SSX22935.1    JH818491    EKC19499.1    AFYH01105981    AFYH01105982    AFYH01105983    AFYH01105984    AFYH01105985    AFYH01105986    AFYH01105987    AFYH01105988    IACJ01085899    LAA49562.1    GAEP01000658    JAB54163.1    IACJ01085894    IACJ01085895    IACJ01085896    IACJ01085898    LAA49552.1    GBSH01002429    JAG66597.1    GFAH01000254    JAV48135.1    GBEX01002142    JAI12418.1    KB201890    ESO93994.1    CM004472    OCT84945.1    BC170489    AAI70489.1    CM004473    OCT82689.1    CAAE01014542    CAF97733.1    GCES01017721    JAR68602.1   

Proteomes

UP000008820    UP000002320    UP000075882    UP000075900    UP000235965    UP000030765    + More
UP000075920    UP000075881    UP000075885    UP000095301    UP000075840    UP000076408    UP000069272    UP000075886    UP000075884    UP000002358    UP000095300    UP000245037    UP000007062    UP000076407    UP000075902    UP000005408    UP000008672    UP000001646    UP000265140    UP000087266    UP000030746    UP000186698    UP000007303    UP000007635    UP000265120    UP000189704    UP000248482   

Pfam

PF00209   SNF

Interpro

IPR037272   SNS_sf        + More
IPR000175   Na/ntran_symport       
IPR003028   Na/ntran_symport_glycine_GLY1       

SUPFAM

SSF161070   SSF161070       

ProteinModelPortal

Q17IX2   B0W8R8   A0A182L090   A0A182RRM3   A0A2J7RFZ9   A0A2J7RFZ4   + More
A0A084W1W0   A0A182WHF4   A0A182KFV4   A0A182PWR0   A0A1I8NA66   T1PIK8   A0A182IBZ0   A0A182Y5H4   A0A182F2C6   A0A182QMM0   A0A182NUT4   K7IUT0   A0A1I8NVU3   A0A1S4GYD1   A0A2P8Z9Q9   Q7Q4L1   A0A0C9QRT5   A0A182X136   A0A1Y1MTC4   A0A182TXD0   A0A336LY90   K1PKZ3   H3A4J1   A0A2D4FQ05   U3ET06   A0A2D4FPZ8   A0A0B8RWB7   G1KQ50   A0A3P8XZP8   A0A1S3KTT1   A0A1S3KSY9   A0A1W7RAG3   A0A0F7Z8A6   V4BY13   A0A1L8GM87   B7ZSD9   A0A1L8GFQ3   H3CR97   Q4SNP9   H3C4F5   A0A146ZRR0   G3PN90   A0A3P8X1L5   A0A3P8X215   A0A3Q0DVD1   A0A2Y9IV28   A0A1U7TJN4  

PDB

4XPH     E-value=4.07799e-108,     Score=1003

KEGG

101744036    K05038 solute carrier family 6 (neurotransmitter transporter, glycine) member 5/9 | (RefSeq) sodium-

GO

GO:0016021   GO:0005328   GO:0015179   GO:0005283   GO:0015187   GO:0005886   GO:0005887   GO:0098794   GO:0060092   GO:0007626   GO:0060080   GO:0098793   GO:0061537   GO:0015293   GO:0006836   GO:0000166   GO:0046872   GO:0016459   GO:0006810   GO:0006397   GO:0004651   GO:0005634  

PANTHER

PTHR11616  

Length:

752

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

267.366539999999

Exp number, first 60 AAs:

36.49812

Total prob of N-in:

0.78291

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  35

outside

36  -  39

TMhelix

40  -  62

inside

63  -  90

TMhelix

91  -  113

outside

114  -  175

TMhelix

176  -  198

inside

199  -  204

TMhelix

205  -  227

outside

228  -  286

TMhelix

287  -  309

inside

310  -  315

TMhelix

316  -  338

outside

339  -  352

TMhelix

353  -  375

inside

376  -  386

TMhelix

387  -  409

outside

410  -  418

TMhelix

419  -  441

inside

442  -  460

TMhelix

461  -  480

outside

481  -  484

TMhelix

485  -  504

inside

505  -  752

 

 

Pi

203.512428

Theta

173.37039

Tajima's D

0.392658

CLR

0.346891

CSRT

0.47667616619169

Interpretation

Uncertain