Gene
KWMTBOMO01805
Pre Gene Modal
BGIBMGA005991
Annotation
PREDICTED:_DNA_primase_large_subunit_isoform_X2_[Bombyx_mori]
Full name
DNA primase large subunit
Alternative Name
Suppressor of fat facets 240
DNA primase 58 kDa subunit
DNA primase 58 kDa subunit
Location in the cell
Nuclear Reliability : 3.798
Sequence
CDS
ATGGATTTCAAAGTTAAAAGAAAATCTACCAAAACTCCAGCAACAGCTACAACTCTTCGAGGGTTGCGTTTAAATTCAGAAGAATTTGTGGAATTCGTACTAAACGATTTACGAGCACAGGGTTTGAAATATTATGCTAAATTGTGTGAGAAATCGGGTTGTGGATCTACTAAAGCAGATTTTGAAGCCCGAAGAAAAGATCACATTGCTCATTTTATACTCCGACTTGCTTATTGTCGGACTGAAGAGTTGCGACGTTGGTTCATCGCAAGGGAATTGGAACTATTCAAAATGAGATTTGCTGTCATGAGAGGCGAAGCGGTAGAGGTATTCTTTAAACTAAACAATCTATGTTACACTACTATTTCTGAAGATGAAAAAAACGAAGTAATACAAAACTTAATAGAATCTACACCCTACTCTAAAATAGACAATATGAAATTCTATAAGGTTAAATTCTTTGAAGTTCTAGATTTGGTTAAAGCAAGAAAAGTATTTCTTAATGATGGATACGCTTATATACCTCACAGAGATTTCATATCAGTTCTTGCAGCACAGTATCGAACACATTTAAAACAAAATTTGGCCAAAGCTTGCCATCATCTGTGTGAAATTGAACAAGATGAACGACTTGTTTGTTTGTTAAAAGGCTTACATCAATCTTATTCAGGTAATGATTATTCTGAAACTAAAGCTGTGATACCCATAGAAAGCTTGGACTCTATTTCAACCAAGTCATTTCCTCTGTGTATGAGGCAACTTCATGAACAATTAAGAATTGCCCATCACTTAAAACATGGGGGCAGGTTACAGTATGGCTTGTTCTTAAAAGGTATTGGTGTGACACTGGAAGACTCTTTAAGGTTTTGGAGGGAAGAATTCATTAAGATTATGGATTTGGATAAATTTGAAAAGCAATATGCTTATAATGTTAGATACAATTATGGAAAAGAAGGAAGCAAAAGGAATTATTCACCATTCAGTTGTCTGAAGATTATAAATACCAATGTTGGTCCTGGAGATTGTCATGGATGTCCATTCAGACACTGTGATACTGGTGTTCTAAAGAATAAACTTATTGGCTATGGTTTTAGTCATCAAGTTGTTTCTGATATAGTGGAGTTGAGCAAGAAAACACATTTCCAAATTGCCTGCAGTAAATATTTTGATGCCATCCACAATGCAGATGTTGGTTTAGGTATCAATCATCCTAATCAGTTCTTTGAGGAGAGTCAGAAAATATTGAAAGGAGAATTGAAAGTACAACCCAAGAAAGAAAATCTTGTGAAGAAAGATATTGTTGACAGCATAGATGCTATGGATTTTGATGAGCCACTGGAATGA
Protein
MDFKVKRKSTKTPATATTLRGLRLNSEEFVEFVLNDLRAQGLKYYAKLCEKSGCGSTKADFEARRKDHIAHFILRLAYCRTEELRRWFIARELELFKMRFAVMRGEAVEVFFKLNNLCYTTISEDEKNEVIQNLIESTPYSKIDNMKFYKVKFFEVLDLVKARKVFLNDGYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSETKAVIPIESLDSISTKSFPLCMRQLHEQLRIAHHLKHGGRLQYGLFLKGIGVTLEDSLRFWREEFIKIMDLDKFEKQYAYNVRYNYGKEGSKRNYSPFSCLKIINTNVGPGDCHGCPFRHCDTGVLKNKLIGYGFSHQVVSDIVELSKKTHFQIACSKYFDAIHNADVGLGINHPNQFFEESQKILKGELKVQPKKENLVKKDIVDSIDAMDFDEPLE
Summary
Description
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Plays a role in the fat facets (faf)-dependent cell-communications pathway.
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Plays a role in the fat facets (faf)-dependent cell-communications pathway.
Cofactor
[4Fe-4S] cluster
Subunit
Heterodimer of a small subunit and a large subunit.
Similarity
Belongs to the eukaryotic-type primase large subunit family.
Keywords
4Fe-4S
Complete proteome
DNA replication
DNA-binding
DNA-directed RNA polymerase
Iron
Iron-sulfur
Metal-binding
Nucleotidyltransferase
Primosome
Reference proteome
Transcription
Transferase
Direct protein sequencing
Phosphoprotein
Feature
chain DNA primase large subunit
Uniprot
H9J8Z9
A0A2A4JA22
A0A2H1WHY5
A0A0L7LS00
A0A194PMM5
A0A194R3T4
+ More
S4PGB7 A0A212ERG6 A0A437BSL0 A0A2J7QUB5 A0A1Q3FVI3 A0A0L0CC58 B4MLK1 A0A0N8DFE7 A0A0P6CJV2 B4IA89 A0A0N8ERN0 A0A1W4W6Y3 E9FRR1 Q0IFM2 A0A1S4F8H6 B4QRX6 A0A2P8ZPK8 A0A087SZT7 I1WYG8 Q9VPH2 B3M979 B3NIK1 A0A2Z5TRX1 W8C2G2 B4IUF6 A0A182GHB7 B4LGE7 B4GR23 A0A1I8NZ21 Q2M0U8 B4KY25 A0A1I8MT64 A0A2L2YIM2 B4IWX1 A0A067RXB7 A0A444TL75 A0A3B0JWC8 A0A0N7Z9R0 A7RM38 A0A034W7G2 A0A0P6EP92 A0A0K8USG3 A0A2I0MU93 A0A3R7MW99 A0A1B0G2I1 V3ZQK5 K1QG59 A0A182JB05 A0A1A9Z746 A0A0M4EJ74 A0A3P9QGK7 C3YQ31 A0A1V4JMM0 A0A096NGX3 A0A084VZ22 F6XMH3 A0A2M4AHR0 A0A2K5V4Z4 F6RQA5 A0A2M4AI89 A0A2I3LTM3 A0A2K5ZT49 A0A369SH43 B5X2T9 G7P2X3 A0JNF4 A0A1A9V5H4 A0A182YLV6 A0A0D9RLW9 P33610 A0A182KAN8 Q3THK0 A0A1L8G3G3 W5P6L0 A0A182VM01 Q7Q5K2 A0A182WCA0 W5JUJ4 A0A182PET3 A0A093PX34 A0A182HI40 A0A091WMC6 H2PJG8 Q5ZM06 A0A315VRS8 A0A2G8JI28 A0A182WTU3 A0A2K5DLM6 A0A182TM34 A0A1W4ZM37 A0A091VZR4 A0A182FEL1 A0A250Y208 A0A182R5J9
S4PGB7 A0A212ERG6 A0A437BSL0 A0A2J7QUB5 A0A1Q3FVI3 A0A0L0CC58 B4MLK1 A0A0N8DFE7 A0A0P6CJV2 B4IA89 A0A0N8ERN0 A0A1W4W6Y3 E9FRR1 Q0IFM2 A0A1S4F8H6 B4QRX6 A0A2P8ZPK8 A0A087SZT7 I1WYG8 Q9VPH2 B3M979 B3NIK1 A0A2Z5TRX1 W8C2G2 B4IUF6 A0A182GHB7 B4LGE7 B4GR23 A0A1I8NZ21 Q2M0U8 B4KY25 A0A1I8MT64 A0A2L2YIM2 B4IWX1 A0A067RXB7 A0A444TL75 A0A3B0JWC8 A0A0N7Z9R0 A7RM38 A0A034W7G2 A0A0P6EP92 A0A0K8USG3 A0A2I0MU93 A0A3R7MW99 A0A1B0G2I1 V3ZQK5 K1QG59 A0A182JB05 A0A1A9Z746 A0A0M4EJ74 A0A3P9QGK7 C3YQ31 A0A1V4JMM0 A0A096NGX3 A0A084VZ22 F6XMH3 A0A2M4AHR0 A0A2K5V4Z4 F6RQA5 A0A2M4AI89 A0A2I3LTM3 A0A2K5ZT49 A0A369SH43 B5X2T9 G7P2X3 A0JNF4 A0A1A9V5H4 A0A182YLV6 A0A0D9RLW9 P33610 A0A182KAN8 Q3THK0 A0A1L8G3G3 W5P6L0 A0A182VM01 Q7Q5K2 A0A182WCA0 W5JUJ4 A0A182PET3 A0A093PX34 A0A182HI40 A0A091WMC6 H2PJG8 Q5ZM06 A0A315VRS8 A0A2G8JI28 A0A182WTU3 A0A2K5DLM6 A0A182TM34 A0A1W4ZM37 A0A091VZR4 A0A182FEL1 A0A250Y208 A0A182R5J9
EC Number
2.7.7.-
Pubmed
19121390
26227816
26354079
23622113
22118469
26108605
+ More
17994087 21292972 17510324 22936249 29403074 11102374 10731132 12537572 10731138 26760975 24495485 17550304 26483478 15632085 25315136 26561354 24845553 17615350 25348373 23371554 23254933 22992520 18563158 24438588 16341006 17431167 25319552 30042472 20433749 22002653 19393038 25244985 8463324 8026492 16141072 15489334 21183079 10349636 11042159 11076861 11217851 12466851 16141073 27762356 20809919 12364791 14747013 17210077 20920257 23761445 15592404 15642098 29703783 29023486 28087693
17994087 21292972 17510324 22936249 29403074 11102374 10731132 12537572 10731138 26760975 24495485 17550304 26483478 15632085 25315136 26561354 24845553 17615350 25348373 23371554 23254933 22992520 18563158 24438588 16341006 17431167 25319552 30042472 20433749 22002653 19393038 25244985 8463324 8026492 16141072 15489334 21183079 10349636 11042159 11076861 11217851 12466851 16141073 27762356 20809919 12364791 14747013 17210077 20920257 23761445 15592404 15642098 29703783 29023486 28087693
EMBL
BABH01004811
NWSH01002391
PCG68384.1
ODYU01008780
SOQ52679.1
JTDY01000232
+ More
KOB78154.1 KQ459601 KPI93984.1 KQ460855 KPJ11900.1 GAIX01003722 JAA88838.1 AGBW02013052 OWR44041.1 RSAL01000014 RVE53321.1 NEVH01011186 PNF32166.1 GFDL01003431 JAV31614.1 JRES01000622 KNC29835.1 CH963847 EDW72857.1 GDIP01039071 LRGB01000248 JAM64644.1 KZS20009.1 GDIQ01090240 JAN04497.1 CH480826 EDW44202.1 GDIQ01000628 JAN94109.1 GL732523 EFX89894.1 CH477312 EAT43881.1 CM000363 CM002912 EDX11222.1 KMZ00760.1 PYGN01000002 PSN58438.1 KK112716 KFM58376.1 BT133488 AFI71918.1 AF291873 AE014296 AF160895 CH902618 EDV40063.1 CH954178 EDV52497.1 FX985810 BBA93697.1 GAMC01010626 JAB95929.1 CM000159 CH891897 EDW95188.1 EDX00020.1 JXUM01063378 KQ562245 KXJ76318.1 CH940647 EDW70476.1 CH479188 EDW40208.1 CH379069 EAL30828.1 CH933809 EDW18727.1 IAAA01022533 LAA07095.1 CH916366 EDV97372.1 KK852405 KDR24534.1 SAUD01001954 RXG70725.1 OUUW01000009 SPP84742.1 GDRN01111611 JAI56744.1 DS469519 EDO47437.1 GAKP01008730 JAC50222.1 GDIQ01073402 JAN21335.1 GDHF01022682 JAI29632.1 AKCR02000002 PKK33256.1 QCYY01002325 ROT71230.1 CCAG010018315 KB203019 ESO86627.1 JH816926 EKC20531.1 CP012525 ALC44940.1 GG666539 EEN57669.1 LSYS01006902 OPJ73429.1 AHZZ02024843 AHZZ02024844 AHZZ02024845 AHZZ02024846 ATLV01018587 KE525239 KFB43216.1 AAEX03008410 GGFK01007008 MBW40329.1 AQIA01051533 AQIA01051534 AQIA01051535 AQIA01051536 AQIA01051537 JSUE03031110 JSUE03031111 JSUE03031112 JSUE03031113 JSUE03031114 JU322951 JU335349 JU476310 JU476311 JU476312 AFE66707.1 AFH33114.1 GGFK01007007 MBW40328.1 NOWV01000010 RDD46235.1 BT045358 ACI33620.1 CM001279 EHH53149.1 BC126657 AAI26658.1 AQIB01132776 AQIB01132777 D13545 D17385 AK076095 AK077760 AK153970 BC019500 AK168246 BAE40196.1 CM004475 OCT78377.1 AMGL01057922 AMGL01057923 AMGL01057924 AMGL01057925 AMGL01057926 AMGL01057927 AMGL01057928 AMGL01057929 AMGL01057930 AMGL01057931 AAAB01008960 EAA11427.3 ADMH02000413 ETN66635.1 KL670319 KFW78760.1 APCN01005875 KK736022 KFR16797.1 ABGA01283624 ABGA01283625 ABGA01283626 ABGA01283627 ABGA01283628 ABGA01283629 ABGA01283630 ABGA01283631 ABGA01283632 ABGA01283633 NDHI03003550 PNJ23843.1 AADN05000003 AJ719578 AJ851645 CAG31237.1 CAH65279.1 NHOQ01001229 PWA25823.1 MRZV01001910 PIK35401.1 KL411479 KFR07983.1 GFFV01002278 JAV37667.1
KOB78154.1 KQ459601 KPI93984.1 KQ460855 KPJ11900.1 GAIX01003722 JAA88838.1 AGBW02013052 OWR44041.1 RSAL01000014 RVE53321.1 NEVH01011186 PNF32166.1 GFDL01003431 JAV31614.1 JRES01000622 KNC29835.1 CH963847 EDW72857.1 GDIP01039071 LRGB01000248 JAM64644.1 KZS20009.1 GDIQ01090240 JAN04497.1 CH480826 EDW44202.1 GDIQ01000628 JAN94109.1 GL732523 EFX89894.1 CH477312 EAT43881.1 CM000363 CM002912 EDX11222.1 KMZ00760.1 PYGN01000002 PSN58438.1 KK112716 KFM58376.1 BT133488 AFI71918.1 AF291873 AE014296 AF160895 CH902618 EDV40063.1 CH954178 EDV52497.1 FX985810 BBA93697.1 GAMC01010626 JAB95929.1 CM000159 CH891897 EDW95188.1 EDX00020.1 JXUM01063378 KQ562245 KXJ76318.1 CH940647 EDW70476.1 CH479188 EDW40208.1 CH379069 EAL30828.1 CH933809 EDW18727.1 IAAA01022533 LAA07095.1 CH916366 EDV97372.1 KK852405 KDR24534.1 SAUD01001954 RXG70725.1 OUUW01000009 SPP84742.1 GDRN01111611 JAI56744.1 DS469519 EDO47437.1 GAKP01008730 JAC50222.1 GDIQ01073402 JAN21335.1 GDHF01022682 JAI29632.1 AKCR02000002 PKK33256.1 QCYY01002325 ROT71230.1 CCAG010018315 KB203019 ESO86627.1 JH816926 EKC20531.1 CP012525 ALC44940.1 GG666539 EEN57669.1 LSYS01006902 OPJ73429.1 AHZZ02024843 AHZZ02024844 AHZZ02024845 AHZZ02024846 ATLV01018587 KE525239 KFB43216.1 AAEX03008410 GGFK01007008 MBW40329.1 AQIA01051533 AQIA01051534 AQIA01051535 AQIA01051536 AQIA01051537 JSUE03031110 JSUE03031111 JSUE03031112 JSUE03031113 JSUE03031114 JU322951 JU335349 JU476310 JU476311 JU476312 AFE66707.1 AFH33114.1 GGFK01007007 MBW40328.1 NOWV01000010 RDD46235.1 BT045358 ACI33620.1 CM001279 EHH53149.1 BC126657 AAI26658.1 AQIB01132776 AQIB01132777 D13545 D17385 AK076095 AK077760 AK153970 BC019500 AK168246 BAE40196.1 CM004475 OCT78377.1 AMGL01057922 AMGL01057923 AMGL01057924 AMGL01057925 AMGL01057926 AMGL01057927 AMGL01057928 AMGL01057929 AMGL01057930 AMGL01057931 AAAB01008960 EAA11427.3 ADMH02000413 ETN66635.1 KL670319 KFW78760.1 APCN01005875 KK736022 KFR16797.1 ABGA01283624 ABGA01283625 ABGA01283626 ABGA01283627 ABGA01283628 ABGA01283629 ABGA01283630 ABGA01283631 ABGA01283632 ABGA01283633 NDHI03003550 PNJ23843.1 AADN05000003 AJ719578 AJ851645 CAG31237.1 CAH65279.1 NHOQ01001229 PWA25823.1 MRZV01001910 PIK35401.1 KL411479 KFR07983.1 GFFV01002278 JAV37667.1
Proteomes
UP000005204
UP000218220
UP000037510
UP000053268
UP000053240
UP000007151
+ More
UP000283053 UP000235965 UP000037069 UP000007798 UP000076858 UP000001292 UP000192221 UP000000305 UP000008820 UP000000304 UP000245037 UP000054359 UP000000803 UP000007801 UP000008711 UP000002282 UP000069940 UP000249989 UP000008792 UP000008744 UP000095300 UP000001819 UP000009192 UP000095301 UP000001070 UP000027135 UP000288706 UP000268350 UP000001593 UP000053872 UP000283509 UP000092444 UP000030746 UP000005408 UP000075880 UP000092445 UP000092553 UP000242638 UP000001554 UP000190648 UP000028761 UP000030765 UP000002254 UP000233100 UP000006718 UP000233140 UP000253843 UP000087266 UP000009130 UP000009136 UP000078200 UP000076408 UP000029965 UP000000589 UP000075881 UP000186698 UP000002356 UP000075903 UP000007062 UP000075920 UP000000673 UP000075885 UP000053258 UP000075840 UP000053605 UP000001595 UP000000539 UP000230750 UP000076407 UP000233020 UP000075902 UP000192224 UP000053283 UP000069272 UP000075900
UP000283053 UP000235965 UP000037069 UP000007798 UP000076858 UP000001292 UP000192221 UP000000305 UP000008820 UP000000304 UP000245037 UP000054359 UP000000803 UP000007801 UP000008711 UP000002282 UP000069940 UP000249989 UP000008792 UP000008744 UP000095300 UP000001819 UP000009192 UP000095301 UP000001070 UP000027135 UP000288706 UP000268350 UP000001593 UP000053872 UP000283509 UP000092444 UP000030746 UP000005408 UP000075880 UP000092445 UP000092553 UP000242638 UP000001554 UP000190648 UP000028761 UP000030765 UP000002254 UP000233100 UP000006718 UP000233140 UP000253843 UP000087266 UP000009130 UP000009136 UP000078200 UP000076408 UP000029965 UP000000589 UP000075881 UP000186698 UP000002356 UP000075903 UP000007062 UP000075920 UP000000673 UP000075885 UP000053258 UP000075840 UP000053605 UP000001595 UP000000539 UP000230750 UP000076407 UP000233020 UP000075902 UP000192224 UP000053283 UP000069272 UP000075900
Pfam
PF04104 DNA_primase_lrg
ProteinModelPortal
H9J8Z9
A0A2A4JA22
A0A2H1WHY5
A0A0L7LS00
A0A194PMM5
A0A194R3T4
+ More
S4PGB7 A0A212ERG6 A0A437BSL0 A0A2J7QUB5 A0A1Q3FVI3 A0A0L0CC58 B4MLK1 A0A0N8DFE7 A0A0P6CJV2 B4IA89 A0A0N8ERN0 A0A1W4W6Y3 E9FRR1 Q0IFM2 A0A1S4F8H6 B4QRX6 A0A2P8ZPK8 A0A087SZT7 I1WYG8 Q9VPH2 B3M979 B3NIK1 A0A2Z5TRX1 W8C2G2 B4IUF6 A0A182GHB7 B4LGE7 B4GR23 A0A1I8NZ21 Q2M0U8 B4KY25 A0A1I8MT64 A0A2L2YIM2 B4IWX1 A0A067RXB7 A0A444TL75 A0A3B0JWC8 A0A0N7Z9R0 A7RM38 A0A034W7G2 A0A0P6EP92 A0A0K8USG3 A0A2I0MU93 A0A3R7MW99 A0A1B0G2I1 V3ZQK5 K1QG59 A0A182JB05 A0A1A9Z746 A0A0M4EJ74 A0A3P9QGK7 C3YQ31 A0A1V4JMM0 A0A096NGX3 A0A084VZ22 F6XMH3 A0A2M4AHR0 A0A2K5V4Z4 F6RQA5 A0A2M4AI89 A0A2I3LTM3 A0A2K5ZT49 A0A369SH43 B5X2T9 G7P2X3 A0JNF4 A0A1A9V5H4 A0A182YLV6 A0A0D9RLW9 P33610 A0A182KAN8 Q3THK0 A0A1L8G3G3 W5P6L0 A0A182VM01 Q7Q5K2 A0A182WCA0 W5JUJ4 A0A182PET3 A0A093PX34 A0A182HI40 A0A091WMC6 H2PJG8 Q5ZM06 A0A315VRS8 A0A2G8JI28 A0A182WTU3 A0A2K5DLM6 A0A182TM34 A0A1W4ZM37 A0A091VZR4 A0A182FEL1 A0A250Y208 A0A182R5J9
S4PGB7 A0A212ERG6 A0A437BSL0 A0A2J7QUB5 A0A1Q3FVI3 A0A0L0CC58 B4MLK1 A0A0N8DFE7 A0A0P6CJV2 B4IA89 A0A0N8ERN0 A0A1W4W6Y3 E9FRR1 Q0IFM2 A0A1S4F8H6 B4QRX6 A0A2P8ZPK8 A0A087SZT7 I1WYG8 Q9VPH2 B3M979 B3NIK1 A0A2Z5TRX1 W8C2G2 B4IUF6 A0A182GHB7 B4LGE7 B4GR23 A0A1I8NZ21 Q2M0U8 B4KY25 A0A1I8MT64 A0A2L2YIM2 B4IWX1 A0A067RXB7 A0A444TL75 A0A3B0JWC8 A0A0N7Z9R0 A7RM38 A0A034W7G2 A0A0P6EP92 A0A0K8USG3 A0A2I0MU93 A0A3R7MW99 A0A1B0G2I1 V3ZQK5 K1QG59 A0A182JB05 A0A1A9Z746 A0A0M4EJ74 A0A3P9QGK7 C3YQ31 A0A1V4JMM0 A0A096NGX3 A0A084VZ22 F6XMH3 A0A2M4AHR0 A0A2K5V4Z4 F6RQA5 A0A2M4AI89 A0A2I3LTM3 A0A2K5ZT49 A0A369SH43 B5X2T9 G7P2X3 A0JNF4 A0A1A9V5H4 A0A182YLV6 A0A0D9RLW9 P33610 A0A182KAN8 Q3THK0 A0A1L8G3G3 W5P6L0 A0A182VM01 Q7Q5K2 A0A182WCA0 W5JUJ4 A0A182PET3 A0A093PX34 A0A182HI40 A0A091WMC6 H2PJG8 Q5ZM06 A0A315VRS8 A0A2G8JI28 A0A182WTU3 A0A2K5DLM6 A0A182TM34 A0A1W4ZM37 A0A091VZR4 A0A182FEL1 A0A250Y208 A0A182R5J9
PDB
5EXR
E-value=5.36982e-105,
Score=974
Ontologies
GO
PANTHER
Topology
Length:
447
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00570000000000001
Exp number, first 60 AAs:
0.00015
Total prob of N-in:
0.02226
outside
1 - 447
Population Genetic Test Statistics
Pi
217.640448
Theta
190.776908
Tajima's D
0.439401
CLR
0.169695
CSRT
0.490875456227189
Interpretation
Uncertain
