Gene

KWMTBOMO01801

Pre Gene Modal

BGIBMGA005993

Annotation

PREDICTED:_toll-like_receptor_8_[Bombyx_mori]

Location

Bomo_Chr4(-):5145524-5149541      View in EpiBrowser

Full name

Protein artichoke      

Location in the cell

PlasmaMembrane   Reliability : 4.923

CDS

ATGAGGGCGTTTTCCTTAATACCGTCTTTAAGTGAACTATCCCTAAGCAACAACATGATCTTAGACGCCACAATGGTTGGTAGAGCTACTAGAGATATTTCTACGCTATCACACTTGAACTTAAATCACAATATAATCGATAAATTGAACGAGGGTGCTTTTGTGGACCAGCCCATGCTGGAGAACCTATTTCTGGCAAATAATAACATAAGCATAATACATCATGGAGCATTCCACAGAGTGCCGAAACTGAGGATAGTTGATTTAAATTACAATAAAATTAGACAAATCCATCCTGAATCATTCTTACAACATTCAGGCAGTGGCGTCGAAGAATTAACACTCATTGGTAATGAAATCAGACATATATCTGAATTTCGTGCGTTGCTCGACGCGTTACCGAGATTAAAATTTCTCGATTTAAGTGACAACCTTCTTCAGGAAATACCTAGGGGTGCACTAAGAGGTCACCCGAGTTTGGAAAGATTGCATTTAAACAAGAATAGCATCAAATTTATACAAACCGATTCATTCGTGGCGATGCCCTCTCTACGAGAATTACATTTGAGCAACAATACTTTATCCGATGTTAATGAAGGCCCATTTTGGGATTTACCTGCACTCAAAGGATTGGACTTGTCATATAATTATTTTCAACGTCTACAGCCAAAACTATTGTACAACTTACCTGCTTTGCGTCGCATAAACTTTAGCCATAATCAATTAAAAGTAGTCGACCCAATAACATTTCTAGAAATACCTCTACTTGAATACGTCAATATATCAGGAAACGCACTGGTATCTTTGCATCCTGCAACATTTAGGAATCTCGAAAATCTTTATGAATTAGATGCGAGTTTCAATAAGCTTATAGAATTTGTTCCGGGACTGCCAAGAGGGCTGGAACAGCTATACTTGCAGAGAAATCAAATCACTAGTTTGCCCGTTACACCTTCGCCTGATCTAGATTTACCGTCACTAAGATCCCTTGACATTTCGAATAACGGCATCCAAAAAATTCCTTTCGGTAGTTTGAAGACGCTTCATAATCTAAGAAGACTGTATATGGAAAGAAACGGTTTAAGGCAAATTGATACATCGACATTTAGTGACCTGGAAAGATTAGAGATATTGGATTTGAGTGAAAATCAAATTATGACTATTCATCCGAAAAGTTTTAGTAAGCTTATTTATCTAAAACAAGTGAACTTACATGGAAATACGGTTGAGAATTTTGATTTCATGACTGTTCAAGAAAATGAGAAGTTATCTTTATTAGACTTAAGCAAAAACAAATTGAATACTCTCAGTCCCAGTATAGTGAACAGAGCACTTGACATAGAGACTTTAAATATTTCGTCGAACAGTTTGAACGAATTACCATCTACCCTCAATCTACTGTCAAAACTGAAAATATTGGACGGTAGCAATAATCACATAAAAAAATTCGCTGGCAATACTATTAACAACTTACAAACACTAATTAATATTAGACTACCGAACAATAAAATTCATGAATTACGTTCTGCCAGTTTTAAAGGTCTAAGAGATTTAGAAATCATTGATTTAGACAATAACAATATTGAAGTCATGCATCAAAAAGCCATTAGCGACTTGCCTAAATTAGTATCGATATACCTTGGAAGAAACCATGTTATCGATTTGCCAGATTTAGTATTCTCCAACCTGCCGAAATTAAGAGTCATAGAATTACAAGGAAATCGTTTGCAACATATTTCTACCAGGGCCTTTGACAATGTTCCTTTGGTACAATACCTCAATTTAAGTAATAACCAAATAACGAAGATTGATGGTTCAGGATTGAAGCTGTTGACGTCATTGGAAGTACTTGATTTGAGTTTTAATAAATTGACAGGAATAACGAGGTCGTCGTTTCAATACATGGAATGGCTGGTTGAACTCAATTTAGATAACAACTTGATATGCCACATTAGCGACCAACCGTTCGATTTAATGCCTCGCCTAAAAGTACTTTCGTTACGCCACAATAAACTACGAGCCGTGTCTGAAACGCCTTTTGAGAAGCTAAGGAATAACATTGCTATTTTAGATTTCGATGGTAATCCCCTGATTTGCAACTGTGCAATCATTTGGCTCAAGTCCTGGCTTTTAGAATCGTCATCGGTGGGCCCGAAATGTGCTGATGGAACTTACGTAAAGGGAATGCCATTTACTCATAGTGATTGTTTTAATATTCATGTATCAGAAGACGATTCAAAATTATGTTTTACCCATGAAAATGAAGCATTGCTACCAAATCTGGCTACATCACAAGTATTTTCGTCTCTAGATAAAATCAAAGATTATGCAAGTGAGATAAAAAATGATTATCACCCTAATAAAGTTCATAGTAGACCATTGCCAGAAGAATCTGATTATTTTTACGATGATTATATTGATTATCCATATAATGATACTATATTGAGTGGTATTAATAATGCAATTACCGAGTTGAATGGAAATAGATCTAAGGAGAACCTTGGCATGACACCGACGCTTTATGCTGAAATGAAGAATACTTCAAGTACTAAGCCAAACCTGACCACAAATGAACCAAGCAGCAGTTTCACATTTTTCGGTATGCCTCTACCACCAATAGATATGAACAAATTACTGAATTCTGGACGTAAAATAGATTGGCCGCAAAAAAGGATCCCGTATCATGGCAACAACTACCAAACGTCAGAACCACCAAAATTTGAAACCGGCGGTTTCAGTCCCATGCTTCCTTCAACTGCTGGAGGCTTCATGCCCATTCCTGGTCCTACGGTTAATTTATCCCACACTATATCAAACACCCAAAGTAACGTAAAATATAACAAAAAGGCAGAAATAGAAAAATCTGTTATTGCAGTAGCGACGCGGCCGCCATTGACAATTTTGAAAAATAACACCGTTCATCAAAAAATGAAAAGTGAAATTCACGAACTCCAAGCCTATTTAGACGATCATAACAGAACTCAAATAGCTTATAATAGAATAAAAAACGTGGAAGAAGAGAAAACTGCACCAAACAATCTTAGTAAGTACAACTTAATGGAGTCTAATTTAACATTAACTCAAGTTACGGAGAAAGAAAGCTTGTTAATTACCACAGATACAAGCAATGATATGTCACTTCAAGCGTGGATGGAAAGCAGTACTATATCTTATTCATCTACACTAAAATCACCAATGCGAAAGCACATTGAAAAACAACCTACAGCATTATCAGCTGTTCTGATCCCAAATAATTTGGAACTGATGCGTAACCACAGTAAGAGGCCAGCAACTATTACTAAAGTTAATATGCCGCATTTAGAACAACATTCTACCTTATATAATTACTCCCCAATAACAAATCGGGAAGGGAAAACAAGGTTTTCAGAAATCACGAACACCGTTAATACAAAAAAGCAACAGATTGACGAGAATGATTGGTACTACCAAAATTACAATAAAACAGACGTAGACCCATATATAGCACCCGGCATACATGCATCAAAGTGTACTTTAGTAGAATTTAATAATTATTTAAAGATTGTAACTCTATTAGTTGTAGTAATAATTTAA

Protein

MRAFSLIPSLSELSLSNNMILDATMVGRATRDISTLSHLNLNHNIIDKLNEGAFVDQPMLENLFLANNNISIIHHGAFHRVPKLRIVDLNYNKIRQIHPESFLQHSGSGVEELTLIGNEIRHISEFRALLDALPRLKFLDLSDNLLQEIPRGALRGHPSLERLHLNKNSIKFIQTDSFVAMPSLRELHLSNNTLSDVNEGPFWDLPALKGLDLSYNYFQRLQPKLLYNLPALRRINFSHNQLKVVDPITFLEIPLLEYVNISGNALVSLHPATFRNLENLYELDASFNKLIEFVPGLPRGLEQLYLQRNQITSLPVTPSPDLDLPSLRSLDISNNGIQKIPFGSLKTLHNLRRLYMERNGLRQIDTSTFSDLERLEILDLSENQIMTIHPKSFSKLIYLKQVNLHGNTVENFDFMTVQENEKLSLLDLSKNKLNTLSPSIVNRALDIETLNISSNSLNELPSTLNLLSKLKILDGSNNHIKKFAGNTINNLQTLINIRLPNNKIHELRSASFKGLRDLEIIDLDNNNIEVMHQKAISDLPKLVSIYLGRNHVIDLPDLVFSNLPKLRVIELQGNRLQHISTRAFDNVPLVQYLNLSNNQITKIDGSGLKLLTSLEVLDLSFNKLTGITRSSFQYMEWLVELNLDNNLICHISDQPFDLMPRLKVLSLRHNKLRAVSETPFEKLRNNIAILDFDGNPLICNCAIIWLKSWLLESSSVGPKCADGTYVKGMPFTHSDCFNIHVSEDDSKLCFTHENEALLPNLATSQVFSSLDKIKDYASEIKNDYHPNKVHSRPLPEESDYFYDDYIDYPYNDTILSGINNAITELNGNRSKENLGMTPTLYAEMKNTSSTKPNLTTNEPSSSFTFFGMPLPPIDMNKLLNSGRKIDWPQKRIPYHGNNYQTSEPPKFETGGFSPMLPSTAGGFMPIPGPTVNLSHTISNTQSNVKYNKKAEIEKSVIAVATRPPLTILKNNTVHQKMKSEIHELQAYLDDHNRTQIAYNRIKNVEEEKTAPNNLSKYNLMESNLTLTQVTEKESLLITTDTSNDMSLQAWMESSTISYSSTLKSPMRKHIEKQPTALSAVLIPNNLELMRNHSKRPATITKVNMPHLEQHSTLYNYSPITNREGKTRFSEITNTVNTKKQQIDENDWYYQNYNKTDVDPYIAPGIHASKCTLVEFNNYLKIVTLLVVVII

Description

Required for normal morphology and function of ciliated sensory organs.

Keywords

Complete proteome   Cytoplasm   Extracellular matrix   Leucine-rich repeat   Reference proteome   Repeat   Secreted   Sensory transduction   Signal  

Feature

chain  Protein artichoke

Uniprot

H9J901   A0A2H1W6A9   A0A2A4K9F1   A0A0L7LRR8   A0A346RAD3   A0A139WH03   + More
A0A154P7B4   A0A1W4XVK0   A0A2P8ZIB7   A0A067RPZ2   A0A1Y1MR07   A0A195CVK3   A0A151WLH3   A0A088AGP8   F4WML6   A0A195FNT9   A0A1B0CYU3   A0A182RXU7   A0A182SNL2   A0A182WE25   A0A182PW33   A0A182Y9J6   B0WLP9   A0A336M1P0   A0A182HEI7   Q17FD9   A0A194PKM3   A0A194R7Q0   A0A2S2QQ53   A0A1J1I3F0   A0A2H8TYX5   A0A2H8TMU3   J9K2Z5   A0A1A9ZDP4   A0A0L0BNM7   E0VC27   A0A1A9W4E0   A0A1B0F9B8   B4H7M6   Q29DD0   B3M9A4   B4IAB4   A0A3B0J5P2   A0A0J9UQ44   Q9VPF0   B3NIM6   B4N6M2   B4LGC7   B4PEU0   A0A1A9UM10   B4KY43   B4QS00   A0A0A1XQJ5   A0A1B0B597   A0A1I8MPZ4   A0A1W4W7X9  

Pubmed

19121390    26227816    29910977    18362917    19820115    29403074    + More
24845553    28004739    21719571    25244985    26483478    17510324    26354079    26108605    20566863    17994087    15632085    23185243    22936249    10731132    12537572    24496014    17550304    25830018    25315136   

EMBL

BABH01004806    ODYU01006621    SOQ48629.1    NWSH01000013    PCG80851.1    JTDY01000232    + More
KOB78153.1    MH200923    AXS59133.1    KQ971343    KYB27278.1    KQ434822    KZC07088.1    PYGN01000048    PSN56249.1    KK852498    KDR22650.1    GEZM01026832    JAV86935.1    KQ977279    KYN04189.1    KQ982959    KYQ48657.1    GL888218    EGI64493.1    KQ981382    KYN42215.1    AJVK01009356    AJVK01009357    DS231989    EDS30614.1    UFQT01000099    SSX19878.1    JXUM01131693    JXUM01131694    CH477271    EAT45306.1    KQ459601    KPI93986.1    KQ460855    KPJ11896.1    GGMS01010655    MBY79858.1    CVRI01000040    CRK94821.1    GFXV01007176    MBW18981.1    GFXV01003678    MBW15483.1    ABLF02031481    JRES01001603    KNC21553.1    DS235045    EEB10933.1    CCAG010023097    CH479219    EDW34666.1    CH379070    EAL30484.2    KRT09001.1    CH902618    EDV40088.1    CH480826    EDW44227.1    OUUW01000002    SPP77147.1    CM002912    KMZ00801.1    AE014296    BT010264    BT125760    BT126058    AAQ23582.1    CH954178    EDV52522.1    CH964161    EDW80011.1    CH940647    EDW70456.1    CM000159    EDW95164.1    CH933809    EDW18745.1    CM000363    EDX11246.1    GBXI01001499    JAD12793.1    JXJN01008650   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007266    UP000076502    UP000192223    + More
UP000245037    UP000027135    UP000078542    UP000075809    UP000005203    UP000007755    UP000078541    UP000092462    UP000075900    UP000075901    UP000075920    UP000075885    UP000076408    UP000002320    UP000069940    UP000008820    UP000053268    UP000053240    UP000183832    UP000007819    UP000092445    UP000037069    UP000009046    UP000091820    UP000092444    UP000008744    UP000001819    UP000007801    UP000001292    UP000268350    UP000000803    UP000008711    UP000007798    UP000008792    UP000002282    UP000078200    UP000009192    UP000000304    UP000092460    UP000095301    UP000192221   

PRIDE

H9J901    Q9VPF0   

Pfam

PF00560   LRR_1        + More
PF13855   LRR_8
PF12799   LRR_4
PF00828   Ribosomal_L27A
PF14770   TMEM18
PF13516   LRR_6
PF13306   LRR_5

Interpro

IPR032675   LRR_dom_sf        + More
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001611   Leu-rich_rpt       
IPR025875   Leu-rich_rpt_4       
IPR013783   Ig-like_fold       
IPR033305   Hydin-like       
IPR000483   Cys-rich_flank_reg_C       
IPR000488   Death_domain       
IPR021131   Ribosomal_L18e/L15P       
IPR036227   L18e/L15P_sf       
IPR026721   TMEM18       
IPR026906   LRR_5       

SUPFAM

SSF52080   SSF52080       

Gene 3D

3.80.10.10     2.60.40.10    

ProteinModelPortal

H9J901   A0A2H1W6A9   A0A2A4K9F1   A0A0L7LRR8   A0A346RAD3   A0A139WH03   + More
A0A154P7B4   A0A1W4XVK0   A0A2P8ZIB7   A0A067RPZ2   A0A1Y1MR07   A0A195CVK3   A0A151WLH3   A0A088AGP8   F4WML6   A0A195FNT9   A0A1B0CYU3   A0A182RXU7   A0A182SNL2   A0A182WE25   A0A182PW33   A0A182Y9J6   B0WLP9   A0A336M1P0   A0A182HEI7   Q17FD9   A0A194PKM3   A0A194R7Q0   A0A2S2QQ53   A0A1J1I3F0   A0A2H8TYX5   A0A2H8TMU3   J9K2Z5   A0A1A9ZDP4   A0A0L0BNM7   E0VC27   A0A1A9W4E0   A0A1B0F9B8   B4H7M6   Q29DD0   B3M9A4   B4IAB4   A0A3B0J5P2   A0A0J9UQ44   Q9VPF0   B3NIM6   B4N6M2   B4LGC7   B4PEU0   A0A1A9UM10   B4KY43   B4QS00   A0A0A1XQJ5   A0A1B0B597   A0A1I8MPZ4   A0A1W4W7X9  

PDB

4QXE     E-value=1.43007e-32,     Score=354

KEGG

101742844    no KO assigned | (RefSeq) toll-like receptor 8

GO

GO:0007165   GO:0016021   GO:0004721   GO:0007423   GO:0040011   GO:0060271   GO:0031012   GO:0005737   GO:0050896   GO:0005515   GO:0009143   GO:0047429   GO:0016459   GO:0006810   GO:0006397   GO:0004651   GO:0005634  

PANTHER

PTHR23053  

Subcellular location

Secreted  
Extracellular space  
Extracellular matrix  
Cytoplasm  

Length:

1190

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02648

Exp number, first 60 AAs:

0.00172

Total prob of N-in:

0.00010

outside

1  -  1190

 

 

Pi

164.726017

Theta

163.132285

Tajima's D

-0.591976

CLR

0.855461

CSRT

0.218689065546723

Interpretation

Uncertain