Gene

KWMTBOMO01799  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005994

Annotation

proteasome_26S_non-ATPase_subunit_7_[Bombyx_mori]

Location

Bomo_Chr4(-):5136608-5138021      View in EpiBrowser

Full name

26S proteasome non-ATPase regulatory subunit 7      

Alternative Name

26S proteasome regulatory subunit RPN8
26S proteasome regulatory subunit S12
Proteasome subunit p39B
Proteasome subunit p40
Protein Mov34

Location in the cell

PlasmaMembrane   Reliability : 4.949

CDS

ATGCCTAGTCAAGAAGTAGCCACCACGAAAGTAACCACCAAAGTGGTGGTTCATCCGTTAGTGTTGCTCAGTGTCGTGGACCATTTTAACCGCATGAGTAAAATCGGGAATCAGAAACGAGTAGTCGGTGTTCTATTGGGTTGTTGGAGAGCCAAGGGTGTCTTAGACGTATCGAACAGCTTCGCAGTCCCGTTTGATGAAGACGACAAAGACAAATCTGTCTGGTTCCTTGACCATGATTACTTAGAGAACATGTATGGTATGTTCAAAAAGGTTAACGCCAGGGAAAAAGTTGTTGGCTGGTACCACACTGGACCTAAACTTCATCAGAATGACATAGCAATAAATGAGTTAATTAGGCGTTATTGCCCAAATTCAGTGCTTGTAATTATTGATGCTAAACCTAAAGATCTTGGTCTACCGACTGAAGCTTACCAAGCAGTAGAGGAAGTACACGATGATGGTACACCAACTTCGAGGACCTTTGAACATGTTCCAAGTGAAATTGGTGCAGAGGAGGCTGAAGAAGTGGGAGTAGAGCATTTGTTAAGAGATATCAAGGATACCACTGTGGGCAGTCTTTCACAGCGTATCACTAACCAGTTGCTCGGCTTAAAAGGTCTTCACTCACAATTGACAGAAATTAGAGATTACCTTGTTCAGGTTGGGCAGGGCTCCTTGCCAATGAACCACCAGATTATTTACCAGTTGCAAGACATCTTCAATTTGCTGCCAGATATTGCTAATGATAATTTCATTGATAATTTGTATGTCAAAACCAATGATCAATCACTTGTGGTATATTTAGCTGCTTTAGTGAGATCCATAATAGCATTACACAATTTGATCAACAATAAAATTACAAATAGAGATGCAGAGGAAGGAAAGAAAGATGAGAAAGATAAAAAAGAAAAAAAAGATGAAAAAGATGATAAAAAAACAGATGAAAAGGCAAAAGTAGAGAAGAAAGATAAAGAAGAGAAGAAAAAATAG

Protein

MPSQEVATTKVTTKVVVHPLVLLSVVDHFNRMSKIGNQKRVVGVLLGCWRAKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQNDIAINELIRRYCPNSVLVIIDAKPKDLGLPTEAYQAVEEVHDDGTPTSRTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQRITNQLLGLKGLHSQLTEIRDYLVQVGQGSLPMNHQIIYQLQDIFNLLPDIANDNFIDNLYVKTNDQSLVVYLAALVRSIIALHNLINNKITNRDAEEGKKDEKDKKEKKDEKDDKKTDEKAKVEKKDKEEKKK

Description

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Similarity

Belongs to the peptidase M67A family.

Keywords

Complete proteome   Direct protein sequencing   Proteasome   Reference proteome  

Feature

chain  26S proteasome non-ATPase regulatory subunit 7

Uniprot

Q1HPL3   A0A2H1W6H0   A0A2A4KAB4   A0A194PMM8   I4DMW2   A0A194R3S9   + More
A0A1E1WDV2   S4PYH4   A0A212EQB3   A0A151WLD7   A0A0M8ZTJ3   A0A2A3E878   A0A088AGS6   A0A026W338   A0A151JCL8   A0A195B4L1   A0A195FQL4   A0A0L7R6K1   E2A9P5   E2C966   A0A0J7NNR7   A0A154P589   F4WML7   A0A2J7QY40   A0A195CU61   A0A067RVM7   K7INV9   A0A232FMB6   A0A1W4XKI4   B0X6E7   A0A182K227   A0A182WD70   A0A1A9V769   Q7PZX6   A0A182ME05   A0A182R1X9   A0A1A9ZUR1   D3TM99   D6WM92   A0A1B0C6J9   J3JVW1   A0A084WM74   A0A182QRN1   A0A182X031   A0A182KT43   A0A182UGA7   A0A182HPP6   A0A182UR01   A0A182YC62   A0A182IK00   A0A1B6CBD7   A0A1A9X3I2   A0A336MEQ9   A0A0A9XNE7   A0A1L8DRU9   B3MFQ8   U5EUH5   Q17PP0   A0A2M4BTL4   A0A2M4BTR9   B4KMJ2   A0A2M4AEP8   A0A182FC07   A0A1Y1M756   A0A3B0JDR3   A0A161ML21   A0A1B0C9N6   T1DTI5   B4H684   B4MYF0   W8C4N0   W5JMV0   A0A1W4W0U9   B3NQI5   A0A0P4VQ04   R4G3V1   A0A0L0BP15   A0A224XU74   A0A069DSK6   A0A0B4KGE6   B4IHF4   B4QBY1   P26270   A0A1I8PG97   A0A1L8ECV9   A0A1I8MJK3   T1PFR0   A0A0K8TMD3   A0A0B4KFH4   B4PB88   B4J4U3   A0A182P1J0   A0A0M4EVI0   A0A034WPP9   A0A1B0EYU8   Q28WV0   A0A0A1X2H8   B4LK61   A0A182GXK1   A0A023ERN2  

Pubmed

19121390    26354079    22651552    23622113    22118469    24508170    + More
30249741    20798317    21719571    24845553    20075255    28648823    12364791    14747013    17210077    20353571    18362917    19820115    22516182    23537049    24438588    20966253    25244985    25401762    26823975    17994087    17510324    28004739    24495485    20920257    23761445    27129103    26108605    26334808    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    2209467    12537569    10893261    25315136    26369729    17550304    25348373    15632085    25830018    26483478    24945155   

EMBL

BABH01004805    DQ443389    ABF51478.1    ODYU01006621    SOQ48627.1    NWSH01000013    + More
PCG80854.1    KQ459601    KPI93989.1    AK402630    BAM19252.1    KQ460855    KPJ11895.1    GDQN01005872    JAT85182.1    GAIX01003283    JAA89277.1    AGBW02013271    OWR43683.1    KQ982959    KYQ48656.1    KQ435896    KOX69333.1    KZ288326    PBC27973.1    KK107455    QOIP01000010    EZA50487.1    RLU17390.1    KQ979054    KYN23196.1    KQ976618    KYM79202.1    KQ981382    KYN42214.1    KQ414646    KOC66505.1    GL437918    EFN69847.1    GL453780    EFN75539.1    LBMM01002954    KMQ94140.1    KQ434822    KZC07089.1    GL888218    EGI64494.1    NEVH01009368    PNF33496.1    KQ977279    KYN04190.1    KK852435    KDR23929.1    KDR23931.1    NNAY01000039    OXU31660.1    DS232412    EDS41430.1    AAAB01008986    EAA00201.4    AXCM01002803    CCAG010023606    EZ422551    ADD18827.1    KQ971343    EFA03341.1    JXJN01026718    APGK01040871    BT127379    KB740984    KB631899    AEE62341.1    ENN76315.1    ERL86960.1    ATLV01024391    KE525351    KFB51318.1    AXCN02001698    APCN01003267    GEDC01026535    JAS10763.1    UFQS01000794    UFQT01000794    SSX06949.1    SSX27293.1    GBHO01025009    GBRD01017224    GDHC01021800    JAG18595.1    JAG48603.1    JAP96828.1    GFDF01004878    JAV09206.1    CH902619    EDV37748.2    GANO01001468    JAB58403.1    CH477190    EAT48711.1    GGFJ01007201    MBW56342.1    GGFJ01007200    MBW56341.1    CH933808    EDW10839.1    GGFK01005922    MBW39243.1    GEZM01040489    JAV80838.1    OUUW01000001    SPP73380.1    GEMB01000053    JAS03056.1    AJWK01002519    GAMD01000944    JAB00647.1    CH479213    EDW33308.1    CH963894    EDW77139.1    GAMC01005394    JAC01162.1    ADMH02000597    ETN65707.1    CH954179    EDV56988.1    GDKW01001509    JAI55086.1    ACPB03002623    GAHY01001346    JAA76164.1    JRES01001578    KNC21825.1    GFTR01004907    JAW11519.1    GBGD01002232    JAC86657.1    AE013599    AGB93698.1    CH480838    EDW49178.1    CM000362    CM002911    EDX08536.1    KMY96322.1    M64643    AY089283    GFDG01002324    JAV16475.1    KA647591    AFP62220.1    GDAI01002518    JAI15085.1    AGB93697.1    CM000158    EDW92520.2    CH916367    EDW00639.1    CP012524    ALC41887.1    GAKP01002650    JAC56302.1    AJVK01035397    CM000071    EAL26566.2    GBXI01009444    JAD04848.1    CH940648    EDW60650.2    JXUM01020611    KQ560576    KXJ81840.1    GAPW01002254    JAC11344.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000075809    + More
UP000053105    UP000242457    UP000005203    UP000053097    UP000279307    UP000078492    UP000078540    UP000078541    UP000053825    UP000000311    UP000008237    UP000036403    UP000076502    UP000007755    UP000235965    UP000078542    UP000027135    UP000002358    UP000215335    UP000192223    UP000002320    UP000075881    UP000075920    UP000078200    UP000007062    UP000075883    UP000075900    UP000092445    UP000092444    UP000007266    UP000092460    UP000019118    UP000030742    UP000030765    UP000075886    UP000076407    UP000075882    UP000075902    UP000075840    UP000075903    UP000076408    UP000075880    UP000091820    UP000007801    UP000008820    UP000009192    UP000069272    UP000268350    UP000092461    UP000008744    UP000007798    UP000000673    UP000192221    UP000008711    UP000015103    UP000037069    UP000000803    UP000001292    UP000000304    UP000095300    UP000095301    UP000002282    UP000001070    UP000075885    UP000092553    UP000092462    UP000001819    UP000008792    UP000069940    UP000249989   

PRIDE

Q1HPL3    A0A088AGS6    P26270   

Pfam

PF13012   MitMem_reg        + More
PF01398   JAB

Interpro

IPR037518   MPN        + More
IPR000555   JAMM/MPN+_dom       
IPR024969   Rpn11/EIF3F_C       
IPR033858   MPN_RPN7_8       

CDD

cd08062  MPN_RPN7_8

ProteinModelPortal

Q1HPL3   A0A2H1W6H0   A0A2A4KAB4   A0A194PMM8   I4DMW2   A0A194R3S9   + More
A0A1E1WDV2   S4PYH4   A0A212EQB3   A0A151WLD7   A0A0M8ZTJ3   A0A2A3E878   A0A088AGS6   A0A026W338   A0A151JCL8   A0A195B4L1   A0A195FQL4   A0A0L7R6K1   E2A9P5   E2C966   A0A0J7NNR7   A0A154P589   F4WML7   A0A2J7QY40   A0A195CU61   A0A067RVM7   K7INV9   A0A232FMB6   A0A1W4XKI4   B0X6E7   A0A182K227   A0A182WD70   A0A1A9V769   Q7PZX6   A0A182ME05   A0A182R1X9   A0A1A9ZUR1   D3TM99   D6WM92   A0A1B0C6J9   J3JVW1   A0A084WM74   A0A182QRN1   A0A182X031   A0A182KT43   A0A182UGA7   A0A182HPP6   A0A182UR01   A0A182YC62   A0A182IK00   A0A1B6CBD7   A0A1A9X3I2   A0A336MEQ9   A0A0A9XNE7   A0A1L8DRU9   B3MFQ8   U5EUH5   Q17PP0   A0A2M4BTL4   A0A2M4BTR9   B4KMJ2   A0A2M4AEP8   A0A182FC07   A0A1Y1M756   A0A3B0JDR3   A0A161ML21   A0A1B0C9N6   T1DTI5   B4H684   B4MYF0   W8C4N0   W5JMV0   A0A1W4W0U9   B3NQI5   A0A0P4VQ04   R4G3V1   A0A0L0BP15   A0A224XU74   A0A069DSK6   A0A0B4KGE6   B4IHF4   B4QBY1   P26270   A0A1I8PG97   A0A1L8ECV9   A0A1I8MJK3   T1PFR0   A0A0K8TMD3   A0A0B4KFH4   B4PB88   B4J4U3   A0A182P1J0   A0A0M4EVI0   A0A034WPP9   A0A1B0EYU8   Q28WV0   A0A0A1X2H8   B4LK61   A0A182GXK1   A0A023ERN2  

PDB

5VHS     E-value=1.62988e-116,     Score=1072

KEGG

733131    K03038 26S proteasome regulatory subunit N8 | (RefSeq) proteasome 26S non-ATPase subunit 7

PATHWAY

03050    Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0005838   GO:0043161   GO:0000502   GO:0003743   GO:0016301   GO:0007623   GO:0005654   GO:0008063   GO:0005829   GO:0008541   GO:0030425   GO:0005515   GO:0005524   GO:0016459   GO:0006810   GO:0006397   GO:0004651   GO:0005634  

Length:

330

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.8007

Exp number, first 60 AAs:

0.17694

Total prob of N-in:

0.06945

outside

1  -  330

 

 

Pi

59.519279

Theta

71.511067

Tajima's D

-0.524142

CLR

256.92929

CSRT

0.234888255587221

Interpretation

Uncertain