Gene

KWMTBOMO01787

Pre Gene Modal

BGIBMGA006153

Annotation

hypothetical_protein_OBRU01_16796?_partial_[Operophtera_brumata]

Location

Bomo_Chr4(+):4651469-4652114      View in EpiBrowser

Full name

Tubulin glycylase 3A      

Location in the cell

Nuclear   Reliability : 2.617

CDS

ATGTTAATACACGAAACAAAATTTGATATAAGGCAATATTATTTGATTACCAGTACATATCCTTTGATTATTTGGATATATAAAGACTGTTATTTGAAGTTCAGCTCTCAGAAATATAACCTTGGAAACTACCATGAATCTATACATTTAACTAACAACGCCGTACAAAGGAGATATATGAACTGTGAAGAGCGCCATCCTGATCTACCCAATAACAATATGTGGGATTTGGATACCTATAAAGATTATTTAAAGGCAATCGGCAAACCCTCGGTGTGGGATGATTTAATATATCCCGGTATGAAAAAGACAATCACAGGTGTGATGCTTAGTAGCCAAGAAACAATGCCGGCTTGCAAGAATCGCTTTGAACTGTACGGTTGCGATTTCCTACTGGACAAAGATTACAAGCCTTGGTTAATCGAAATCAATGCATGCCCTGATCTCAACAGTACCACACGAGTCACCGCGAAAATTTGTCCGGCCGTTTTAGCTGATGTCATTAAAGGTTTGATATAA

Protein

MLIHETKFDIRQYYLITSTYPLIIWIYKDCYLKFSSQKYNLGNYHESIHLTNNAVQRRYMNCEERHPDLPNNNMWDLDTYKDYLKAIGKPSVWDDLIYPGMKKTITGVMLSSQETMPACKNRFELYGCDFLLDKDYKPWLIEINACPDLNSTTRVTAKICPAVLADVIKGLI

Description

Polylycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved both in the side-chain initiation and elongation steps of the polyglycylation reaction by adding a single glycine chain to generate monoglycine side chains and by elongating monoglycine side chains to polyglycine side chains.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Cytoskeleton   Ligase   Microtubule   Nucleotide-binding   Reference proteome  

Feature

chain  Tubulin glycylase 3A

Uniprot

H9J9G0   A0A0L7KY04   A0A2H1WWR1   A0A212F7D8   A0A194R3R9   A0A194PMN9   + More
A0A2A4K994   H9J9F9   A0A1Y1LE01   A0A1Y1LLK0   A0A2A4KA36   A0A194R2Y8   A0A212F7E8   A0A1B6L156   A0A1B0GHY1   A0A1B0GQ96   A0A0L0C2V8   A0A1B6IUI5   A0A1Y1LIV3   A0A1B6JCV0   A0A1B6LW88   A0A1I8MX16   A0A088AGQ7   A0A1I8PR05   A0A2A3EDF0   A0A1W4WKB8   A0A1B6J6Z4   A0A1J1IE64   A0A1A9ZFE1   A0A1A9VF55   A0A1B6MFR9   A0A1B6DSQ9   A0A1B0FAA3   A0A3L8DD51   B4LRK5   A0A1Y1LG93   A0A1A9W5H6   A0A1B6G8A6   A0A1B6FPT8   B4KL62   A0A0J9QY02   A0A0M9AAH7   A0A084VK39   Q9VM91   B4HXX2   B3N5W4   B4P018   B3MKL8   A0A1W4UBD6   A0A154P7K7   B4JB87   B0WKD5   A0A0M4E3Y7   A0A1B6H008   A0A1B6L0Z4   Q29P16   E1ZXT0   A0A139WHK4   B4GJX5   A0A0J7L6G8   A0A1B6IKE7   A0A1A9XQP7   A0A0K8T179   A0A026WJT5   E2B9Y4   A0A0K8T169   A0A3B0KIW8   Q7Q156   A0A1B0BN49   Q17NV1   A0A1S4EWD3   A0A182WRE8   A0A158P470   A0A1B6KRF3   B4N1E9   A0A232FAY4   A0A1I8IQ12   A0A267H1G7   A0A1I8HUU7   K7JAY6   A0A1W4W909   A0A267E3V8   F4WIQ5   A0A182LS70   W5JPW2   A0A182QWW9   A0A182U9C5   A0A182H0X3   A0A1I8GTN0   A0A182V6D4   A0A1B6FI59   A0A1B6EMD8   A0A267H6M3   A0A182JSX6   A0A182F296   A0A195BNU9   A0A182W8U6   A0A182HRC3   A0A182PIX4   A0A182RWT9  

EC Number

6.3.2.-

Pubmed

19121390    26227816    22118469    26354079    28004739    26108605    + More
25315136    30249741    17994087    22936249    24438588    10731132    12537572    19524510    17550304    15632085    20798317    18362917    19820115    24508170    12364791    17510324    21347285    28648823    26392545    20075255    21719571    20920257    23761445    26483478   

EMBL

BABH01004776    JTDY01004642    KOB67919.1    ODYU01011578    SOQ57406.1    AGBW02009882    + More
OWR49655.1    KQ460855    KPJ11885.1    KQ459601    KPI93999.1    NWSH01000013    PCG80845.1    BABH01004775    GEZM01058134    JAV71879.1    GEZM01058136    JAV71877.1    PCG80846.1    KPJ11884.1    OWR49656.1    GEBQ01022535    JAT17442.1    AJWK01010432    AJVK01006597    JRES01000973    KNC26660.1    GECU01017186    JAS90520.1    GEZM01058137    JAV71875.1    GECU01010640    JAS97066.1    GEBQ01012035    JAT27942.1    KZ288283    PBC29514.1    GECU01012772    JAS94934.1    CVRI01000047    CRK98567.1    GEBQ01005238    JAT34739.1    GEDC01008582    JAS28716.1    CCAG010016184    QOIP01000010    RLU18082.1    CH940649    EDW63600.1    GEZM01058135    JAV71878.1    GECZ01011081    GECZ01005312    JAS58688.1    JAS64457.1    GECZ01017579    GECZ01004738    JAS52190.1    JAS65031.1    CH933807    EDW11723.1    CM002910    KMY88609.1    KQ435700    KOX80565.1    ATLV01014106    KE524943    KFB38333.1    AE014134    CH480818    EDW51902.1    CH954177    EDV59123.1    CM000157    EDW87845.1    CH902620    EDV31571.1    KQ434822    KZC07100.1    CH916368    EDW02892.1    DS231970    EDS29740.1    CP012523    ALC38434.1    GECZ01001763    JAS68006.1    GEBQ01022614    JAT17363.1    CH379058    EAL34477.2    GL435087    EFN74052.1    KQ971343    KYB27443.1    CH479184    EDW36941.1    LBMM01000547    KMQ98084.1    GECU01020318    JAS87388.1    GBRD01006538    JAG59283.1    KK107167    EZA56223.1    GL446618    EFN87487.1    GBRD01006539    JAG59282.1    OUUW01000010    SPP85706.1    AAAB01008980    EAA13905.3    JXJN01017195    CH477196    EAT48373.1    ADTU01008677    GEBQ01025960    JAT14017.1    CH963920    EDW78060.1    NNAY01000494    OXU28004.1    NIVC01000089    PAA91402.1    AAZX01007838    NIVC01002647    PAA56255.1    GL888177    EGI65851.1    AXCM01001818    ADMH02000503    ETN66181.1    AXCN02001993    JXUM01003334    JXUM01003335    JXUM01003336    JXUM01003337    JXUM01003338    JXUM01003339    JXUM01003340    JXUM01003341    KQ560156    KXJ84138.1    GECZ01019878    JAS49891.1    GECZ01030690    JAS39079.1    NIVC01000019    PAA93940.1    KQ976435    KYM87039.1    APCN01001680   

Proteomes

UP000005204    UP000037510    UP000007151    UP000053240    UP000053268    UP000218220    + More
UP000092461    UP000092462    UP000037069    UP000095301    UP000005203    UP000095300    UP000242457    UP000192223    UP000183832    UP000092445    UP000078200    UP000092444    UP000279307    UP000008792    UP000091820    UP000009192    UP000053105    UP000030765    UP000000803    UP000001292    UP000008711    UP000002282    UP000007801    UP000192221    UP000076502    UP000001070    UP000002320    UP000092553    UP000001819    UP000000311    UP000007266    UP000008744    UP000036403    UP000092443    UP000053097    UP000008237    UP000268350    UP000007062    UP000092460    UP000008820    UP000076407    UP000005205    UP000007798    UP000215335    UP000095280    UP000215902    UP000002358    UP000007755    UP000075883    UP000000673    UP000075886    UP000075902    UP000069940    UP000249989    UP000075903    UP000075881    UP000069272    UP000078540    UP000075920    UP000075840    UP000075885    UP000075900   

PRIDE

H9J9G0    H9J9F9    Q9VM91   

Pfam

PF03133   TTL        + More
PF15346   ARGLU
PF04193   PQ-loop
PF13499   EF-hand_7

Interpro

IPR033371   ARGLU1        + More
IPR004344   TTL/TTLL_fam       
IPR006603   PQ-loop_rpt       
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR018247   EF_Hand_1_Ca_BS       
IPR013815   ATP_grasp_subdomain_1       

SUPFAM

SSF47473   SSF47473       

Gene 3D

3.30.1490.20    

CDD

cd00051  EFh

ProteinModelPortal

H9J9G0   A0A0L7KY04   A0A2H1WWR1   A0A212F7D8   A0A194R3R9   A0A194PMN9   + More
A0A2A4K994   H9J9F9   A0A1Y1LE01   A0A1Y1LLK0   A0A2A4KA36   A0A194R2Y8   A0A212F7E8   A0A1B6L156   A0A1B0GHY1   A0A1B0GQ96   A0A0L0C2V8   A0A1B6IUI5   A0A1Y1LIV3   A0A1B6JCV0   A0A1B6LW88   A0A1I8MX16   A0A088AGQ7   A0A1I8PR05   A0A2A3EDF0   A0A1W4WKB8   A0A1B6J6Z4   A0A1J1IE64   A0A1A9ZFE1   A0A1A9VF55   A0A1B6MFR9   A0A1B6DSQ9   A0A1B0FAA3   A0A3L8DD51   B4LRK5   A0A1Y1LG93   A0A1A9W5H6   A0A1B6G8A6   A0A1B6FPT8   B4KL62   A0A0J9QY02   A0A0M9AAH7   A0A084VK39   Q9VM91   B4HXX2   B3N5W4   B4P018   B3MKL8   A0A1W4UBD6   A0A154P7K7   B4JB87   B0WKD5   A0A0M4E3Y7   A0A1B6H008   A0A1B6L0Z4   Q29P16   E1ZXT0   A0A139WHK4   B4GJX5   A0A0J7L6G8   A0A1B6IKE7   A0A1A9XQP7   A0A0K8T179   A0A026WJT5   E2B9Y4   A0A0K8T169   A0A3B0KIW8   Q7Q156   A0A1B0BN49   Q17NV1   A0A1S4EWD3   A0A182WRE8   A0A158P470   A0A1B6KRF3   B4N1E9   A0A232FAY4   A0A1I8IQ12   A0A267H1G7   A0A1I8HUU7   K7JAY6   A0A1W4W909   A0A267E3V8   F4WIQ5   A0A182LS70   W5JPW2   A0A182QWW9   A0A182U9C5   A0A182H0X3   A0A1I8GTN0   A0A182V6D4   A0A1B6FI59   A0A1B6EMD8   A0A267H6M3   A0A182JSX6   A0A182F296   A0A195BNU9   A0A182W8U6   A0A182HRC3   A0A182PIX4   A0A182RWT9  

PDB

5VLQ     E-value=1.742e-44,     Score=447

KEGG

101741583    K16608 tubulin monoglycylase TTLL3/8 [EC:6.3.2.-] | (RefSeq) tubulin glycylase 3A-like

GO

GO:0006464   GO:0016021   GO:0018094   GO:0070735   GO:0070736   GO:0015630   GO:0070737   GO:0005737   GO:0005524   GO:0005874   GO:0016874   GO:0005509   GO:0006468   GO:0005515   GO:0003774   GO:0016459   GO:0006810   GO:0006397   GO:0004651   GO:0005634  

Subcellular location

  

Length:

172

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

6.49663999999999

Exp number, first 60 AAs:

6.49584

Total prob of N-in:

0.14355

outside

1  -  172

 

 

Pi

310.206653

Theta

212.03484

Tajima's D

1.45769

CLR

0

CSRT

0.781110944452777

Interpretation

Uncertain