Gene

KWMTBOMO01786

Pre Gene Modal

BGIBMGA006152

Annotation

PREDICTED:_tubulin_glycylase_3A-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr4(+):4643569-4647165      View in EpiBrowser

Full name

Tubulin glycylase 3A      

Location in the cell

Cytoplasmic   Reliability : 2.222 Nuclear   Reliability : 1.571

CDS

ATGGAATTAGAGGAAAGTGTATCAGACTCCAAGCTCCACAAAGAGAGTACGGCTAAAAAAGATTTAAGGCCTTCTAGCGCTATCTCGTTTTCTAAATCTGATCATGGCCCAGAAACAACTTCATCAACGGAACAACTTCGTCAGTATAAAAGTTGGGTCAGCAACGAAAGGTGGAATGAATTGAAAAAGATCGCGGAAACAGCGATGAAACAACGTAAGGTTTTCATGATTAAAGGCGGCGGTTTCCCAGCAATCCGTCGGGCCATGCTTGAACGAGGCTGGGTAGAAAAATATGAATCCCATAAGGTACGTCATCCTCCAACAAACGTAGATCCTAAAAAAGCGTCTGGCAAAGAGCTCTCCAAAGTAGAAAGAATGATACTCTACAAGTTCATGGAACATCACTCTGTTGATTTTCTATGGACGACCAAACGTGATAAATATGATTGGTTACTTAGTAACAAAGATGTCATGATAAGCAGATTTTGTAGATCCGTGTTCACGACGAAAGAGGGTTTAACTGCTTCGTTGACGCAAATGCATTGGCACACTGAGCCTGGGATTGCACTTACGAAGTTTCCACGATGCTACAATATACACAACTCTGATAGCCTCGAAGAATTCGTCGATGACTTTAGGATCACGGCCTGTATCAGCGTTCTTAAATGGCTTTGTAGTACTTTACAAATCAATGGAGAACAAAATCTAATTTCGAATCAGGGGAAAGTTCCTTTCAGCGCCATTGAATTTGCCACCAGTAGACTAAACGAATATGTTTTGTTCTTTACACATAAAGACATCGATGATACAGAGGAACAGGTCCATGTTTGGGAACACGAATGGGATCAATTCTTAACTCACCATTACCTTCTCGTGCACGAAAAAGCAAAGTTTAGCAATGATAACAATACAAGTATAAGGCAACTCGAAAGAAAAGCGTCTAAGGTTTTAACTACGATGAGCAAGTTCTGGCCTCAAATCGATATTGATGGTGTGCTCAATATTTGGATCGTAAAGCCTGGTAACAAATGCCGAGGTAGAGGTATTCAGCTCATGAATAATATAAAGGATATAATTGGCTTAATTAATATTCCTGTACAGAAAACAAGATATGTTGTGCAAAAGTACATTGAAAATCCATTAGTGATTTACGACACAAAATTCGACATAAGGCAGTGGTTTCTGATCACTAACTGTCAACCGTTAACAATATGGGTTTACAAGGACAGCTACCTACGATTTAGTTCACAGATATTCAGCCTCTCTAACTATCACGAATCGGTTCACCTAACCAACAATGCTGTTCAAACTAAATACAAGAATAATGAGGACAGAGACAAAGCTTTACCCGACGAGAACATGTGGGACTGTCACACGTTTAAGGCCTATCTAAAACAGATCGGTAAATATGAACTGTGGGACACTAAAATATATCCTGGAATGAAACAATGTTTGGTTGGAGCAATGTTGGCCTGCCAAGAAACAATGGATAAGAGACAGAACAGCTTTGAGCTTTACGGAGCTGATTTTATGCTTACTGAAGACTTTACACCTTGGCTCATTGAAATTAACTCCAGTCCAGATTTAGCACCTACTACTTCAGTTACGGCTAGGTTATGTCCTCAGTGTCTAGAAGATGTAATCAAAGTTGTTTTAGATCGCCGCTTAAATCCAGATGCTGACACAGGAACTTTTGAGTTAGCCTACAGGCAAACTATACCGAAAGCACCGGCATATCTTGGGTTGTCACTTTGTATCAACGGTAAAAGACTTTTTAAGAAGTCGAGAGAGAAAAAGCATGATACGAGAAGTATTACACCGGTAGCACCACGAGAACCAGCTGGCGATACCATTCCCGATGCAGACCTACCCGTTCCCCCCGAATATTCGGGACCTATTATCACGGATTTCCTCAGCTGGTTAAACCCTTATGATGCTCTGCCTTGTAATAAGGATGGTATTTTATTAGGTCCCAAAGATTCATTGACGGACACACCGAGGAAGAAAAGAAAAAACGGAATTTAA

Protein

MELEESVSDSKLHKESTAKKDLRPSSAISFSKSDHGPETTSSTEQLRQYKSWVSNERWNELKKIAETAMKQRKVFMIKGGGFPAIRRAMLERGWVEKYESHKVRHPPTNVDPKKASGKELSKVERMILYKFMEHHSVDFLWTTKRDKYDWLLSNKDVMISRFCRSVFTTKEGLTASLTQMHWHTEPGIALTKFPRCYNIHNSDSLEEFVDDFRITACISVLKWLCSTLQINGEQNLISNQGKVPFSAIEFATSRLNEYVLFFTHKDIDDTEEQVHVWEHEWDQFLTHHYLLVHEKAKFSNDNNTSIRQLERKASKVLTTMSKFWPQIDIDGVLNIWIVKPGNKCRGRGIQLMNNIKDIIGLINIPVQKTRYVVQKYIENPLVIYDTKFDIRQWFLITNCQPLTIWVYKDSYLRFSSQIFSLSNYHESVHLTNNAVQTKYKNNEDRDKALPDENMWDCHTFKAYLKQIGKYELWDTKIYPGMKQCLVGAMLACQETMDKRQNSFELYGADFMLTEDFTPWLIEINSSPDLAPTTSVTARLCPQCLEDVIKVVLDRRLNPDADTGTFELAYRQTIPKAPAYLGLSLCINGKRLFKKSREKKHDTRSITPVAPREPAGDTIPDADLPVPPEYSGPIITDFLSWLNPYDALPCNKDGILLGPKDSLTDTPRKKRKNGI

Description

Polylycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved both in the side-chain initiation and elongation steps of the polyglycylation reaction by adding a single glycine chain to generate monoglycine side chains and by elongating monoglycine side chains to polyglycine side chains.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Cytoskeleton   Ligase   Microtubule   Nucleotide-binding   Reference proteome  

Feature

chain  Tubulin glycylase 3A

Uniprot

H9J9F9   A0A2A4KA36   A0A212F7E8   A0A194R2Y8   B0WKD5   Q17NV1   + More
A0A1S4EWD3   A0A182H0X3   A0A182F296   A0A182IQI5   A0A1B0GQ96   W5JPW2   A0A182Y6C8   A0A084VK39   A0A182RWT9   A0A182W8U6   A0A182PIX4   A0A182LS70   A0A182NNW1   A0A182JSX6   A0A1B0GHY1   A0A182QWW9   A0A182V6D4   A0A182U9C5   A0A182HRC3   A0A1W4WKB8   Q7Q156   Q9VM91   A0A0J9QY02   B4P018   B3N5W4   B4LRK5   B4HXX2   B4JB87   A0A1W4UBD6   Q29P16   B4GJX5   A0A139WHK4   B4KL62   B4N1E9   A0A3B0KIW8   B3MKL8   A0A0M4E3Y7   A0A1Y1LLK0   A0A1A9ZFE1   A0A1Y1LE01   A0A1A9VF55   A0A1B0BN49   A0A1A9XQP7   A0A1B0FAA3   A0A1J1IE64   A0A1I8MX16   A0A1I8PR05   A0A0K8T169   A0A182WRE8   A0A0L0C2V8   A0A0K8T179   K7JAY6   E2B9Y4   A0A1A9W5H6   A0A1B6KRF3   U4UI03   A0A232FAY4   E9IIQ2   A0A1B6H008   A0A088AGQ7   A0A3L8DD51   A0A158P470   A0A2A3EDF0   A0A026WJT5   A0A0C9RKZ2   A0A1B6DSQ9   E1ZXT0   A0A195FQV5   A0A195CUA4   A0A0M9AAH7   T1HZX4   A0A0C9R444   A0A151JR50   A0A151WLP9   A0A154P7K7   A0A3Q0JF14   A0A195BNU9   F4WIQ5   E0VS30   N6UFF3   A0A0K2TGN2   A0A1D2NL41   A7RW52   A0A139WHL0   A0A2A4K994   A0A1B6FI59   A0A1B6EMD8   A0A088AGQ9   A0A194R3R9  

EC Number

6.3.2.-

Pubmed

19121390    22118469    26354079    17510324    26483478    20920257    + More
23761445    25244985    24438588    12364791    10731132    12537572    19524510    22936249    17994087    17550304    15632085    18362917    19820115    28004739    25315136    26108605    20075255    20798317    23537049    28648823    21282665    30249741    21347285    24508170    21719571    20566863    27289101    17615350   

EMBL

BABH01004775    NWSH01000013    PCG80846.1    AGBW02009882    OWR49656.1    KQ460855    + More
KPJ11884.1    DS231970    EDS29740.1    CH477196    EAT48373.1    JXUM01003334    JXUM01003335    JXUM01003336    JXUM01003337    JXUM01003338    JXUM01003339    JXUM01003340    JXUM01003341    KQ560156    KXJ84138.1    AJVK01006597    ADMH02000503    ETN66181.1    ATLV01014106    KE524943    KFB38333.1    AXCM01001818    AJWK01010432    AXCN02001993    APCN01001680    AAAB01008980    EAA13905.3    AE014134    CM002910    KMY88609.1    CM000157    EDW87845.1    CH954177    EDV59123.1    CH940649    EDW63600.1    CH480818    EDW51902.1    CH916368    EDW02892.1    CH379058    EAL34477.2    CH479184    EDW36941.1    KQ971343    KYB27443.1    CH933807    EDW11723.1    CH963920    EDW78060.1    OUUW01000010    SPP85706.1    CH902620    EDV31571.1    CP012523    ALC38434.1    GEZM01058136    JAV71877.1    GEZM01058134    JAV71879.1    JXJN01017195    CCAG010016184    CVRI01000047    CRK98567.1    GBRD01006539    JAG59282.1    JRES01000973    KNC26660.1    GBRD01006538    JAG59283.1    AAZX01007838    GL446618    EFN87487.1    GEBQ01025960    JAT14017.1    KB632364    ERL93609.1    NNAY01000494    OXU28004.1    GL763505    EFZ19550.1    GECZ01001763    JAS68006.1    QOIP01000010    RLU18082.1    ADTU01008677    KZ288283    PBC29514.1    KK107167    EZA56223.1    GBYB01007581    JAG77348.1    GEDC01008582    JAS28716.1    GL435087    EFN74052.1    KQ981382    KYN42289.1    KQ977279    KYN04107.1    KQ435700    KOX80565.1    ACPB03006613    GBYB01007582    JAG77349.1    KQ978615    KYN29843.1    KQ982959    KYQ48737.1    KQ434822    KZC07100.1    KQ976435    KYM87039.1    GL888177    EGI65851.1    DS235742    EEB16186.1    APGK01037623    APGK01037624    KB740948    ENN77387.1    HACA01007285    CDW24646.1    LJIJ01000012    ODN05957.1    DS469545    EDO44351.1    KYB27442.1    PCG80845.1    GECZ01019878    JAS49891.1    GECZ01030690    JAS39079.1    KPJ11885.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000002320    UP000008820    + More
UP000069940    UP000249989    UP000069272    UP000075880    UP000092462    UP000000673    UP000076408    UP000030765    UP000075900    UP000075920    UP000075885    UP000075883    UP000075884    UP000075881    UP000092461    UP000075886    UP000075903    UP000075902    UP000075840    UP000192223    UP000007062    UP000000803    UP000002282    UP000008711    UP000008792    UP000001292    UP000001070    UP000192221    UP000001819    UP000008744    UP000007266    UP000009192    UP000007798    UP000268350    UP000007801    UP000092553    UP000092445    UP000078200    UP000092460    UP000092443    UP000092444    UP000183832    UP000095301    UP000095300    UP000076407    UP000037069    UP000002358    UP000008237    UP000091820    UP000030742    UP000215335    UP000005203    UP000279307    UP000005205    UP000242457    UP000053097    UP000000311    UP000078541    UP000078542    UP000053105    UP000015103    UP000078492    UP000075809    UP000076502    UP000079169    UP000078540    UP000007755    UP000009046    UP000019118    UP000094527    UP000001593   

PRIDE

H9J9F9    Q9VM91   

Pfam

PF03133   TTL

Interpro

IPR004344   TTL/TTLL_fam        + More
IPR013815   ATP_grasp_subdomain_1       

Gene 3D

3.30.1490.20    

ProteinModelPortal

H9J9F9   A0A2A4KA36   A0A212F7E8   A0A194R2Y8   B0WKD5   Q17NV1   + More
A0A1S4EWD3   A0A182H0X3   A0A182F296   A0A182IQI5   A0A1B0GQ96   W5JPW2   A0A182Y6C8   A0A084VK39   A0A182RWT9   A0A182W8U6   A0A182PIX4   A0A182LS70   A0A182NNW1   A0A182JSX6   A0A1B0GHY1   A0A182QWW9   A0A182V6D4   A0A182U9C5   A0A182HRC3   A0A1W4WKB8   Q7Q156   Q9VM91   A0A0J9QY02   B4P018   B3N5W4   B4LRK5   B4HXX2   B4JB87   A0A1W4UBD6   Q29P16   B4GJX5   A0A139WHK4   B4KL62   B4N1E9   A0A3B0KIW8   B3MKL8   A0A0M4E3Y7   A0A1Y1LLK0   A0A1A9ZFE1   A0A1Y1LE01   A0A1A9VF55   A0A1B0BN49   A0A1A9XQP7   A0A1B0FAA3   A0A1J1IE64   A0A1I8MX16   A0A1I8PR05   A0A0K8T169   A0A182WRE8   A0A0L0C2V8   A0A0K8T179   K7JAY6   E2B9Y4   A0A1A9W5H6   A0A1B6KRF3   U4UI03   A0A232FAY4   E9IIQ2   A0A1B6H008   A0A088AGQ7   A0A3L8DD51   A0A158P470   A0A2A3EDF0   A0A026WJT5   A0A0C9RKZ2   A0A1B6DSQ9   E1ZXT0   A0A195FQV5   A0A195CUA4   A0A0M9AAH7   T1HZX4   A0A0C9R444   A0A151JR50   A0A151WLP9   A0A154P7K7   A0A3Q0JF14   A0A195BNU9   F4WIQ5   E0VS30   N6UFF3   A0A0K2TGN2   A0A1D2NL41   A7RW52   A0A139WHL0   A0A2A4K994   A0A1B6FI59   A0A1B6EMD8   A0A088AGQ9   A0A194R3R9  

PDB

5VLQ     E-value=6.65287e-101,     Score=940

KEGG

101741442    K16608 tubulin monoglycylase TTLL3/8 [EC:6.3.2.-] | (RefSeq) tubulin glycylase 3A-like

GO

GO:0006464   GO:0005524   GO:0018094   GO:0005737   GO:0015630   GO:0070737   GO:0070735   GO:0070736   GO:0005874   GO:0016874   GO:0006468   GO:0005515   GO:0003774   GO:0016459   GO:0006810   GO:0006397   GO:0004651   GO:0005634  

Subcellular location

  

Length:

674

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01566

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00021

outside

1  -  674

 

 

Pi

205.87713

Theta

189.62094

Tajima's D

0.392398

CLR

0

CSRT

0.487625618719064

Interpretation

Uncertain