Gene

KWMTBOMO01757  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006141

Annotation

eukaryotic_translation_initiation_factor_3_subunit_H_[Bombyx_mori]

Location

Bomo_Chr4(+):3748514-3752189      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit H      

Location in the cell

PlasmaMembrane   Reliability : 3.789

CDS

ATGGCGAGCCGTGCTGGTTCAGCTAGACGCGCTCCTGAAAATGAAGCGACGATCCAATATGTTCAGTGCGATGGACTGGCAGTGATGAAAATAGTGAAACACTGTCATGAAGAATCATGCAGCAACATGGAGGTGGCTCAGGGAGCTCTCCTTGGTTTGGTCGTTGAGAACCGTCTGGAGATTACCAACTGCTTCCCATTTCCAAAGCATGACGACACCATGGATGAGGAGGAATACCAGTTGGACATGATGAGGAGGCTTCGAAGAGTCAATGTTGATCATTTTCATGTTGGATGGTACCAGAGTGCAGATGTAGGCAATTTTCTAAGCCTTTCGTTATTAGAGTCACAATATCACTATCAGACCTCTATTGAGGAGAGTGTTGTTGTGATTTACGATACAAAGAAATCAGCCAGAGGATTCTTGACTTTGAAGGCCTATCGTTTGACACCTCAGGCTATTGCTATGTACAAGGAAGGCGATTACACTCCGGAAGCACTACGTAACCTGAAGATTGGCTATGAAAATCTATTCATTGAAGTGCCAATTGTTATCCGGAACTCTCCATTAACTAACATAATGATCTCTGAGCTCACCGAGATGATACCTGAAGAGGAAGGATCCAAGTTTTTGGATCTGGGTACTGCATCTGTTCTCGAAGGACAACTTCGCAGTCTCATGGAACGTGTTGATGAACTGAATCAAGAAGCGATCAAGTTCAATAGGTACCAACAGCTGGTGGTCAGGCAGCAACAAGACAAGCATCGTTGGATGGTGAAGAGGGCACAGGAAAATGCTGCTAGGGCTGCTAAAGATGAGACCCCGTTGCCAGAAGAAGACGTGAACAAACTCTTTAAACCTCATCCAGTCCCGCCAAGGTTGAATCCTATGATCGTAGCCGGACAAATAGACACATACAGCCAACATATAAGCCAGTTCTGTAGTCAGAGTCTAGCGAAATTGTATTTGACTCAGGCTCTTCAGAACGCGAAAGAAGCGAAACAAAACAACTAG

Protein

MASRAGSARRAPENEATIQYVQCDGLAVMKIVKHCHEESCSNMEVAQGALLGLVVENRLEITNCFPFPKHDDTMDEEEYQLDMMRRLRRVNVDHFHVGWYQSADVGNFLSLSLLESQYHYQTSIEESVVVIYDTKKSARGFLTLKAYRLTPQAIAMYKEGDYTPEALRNLKIGYENLFIEVPIVIRNSPLTNIMISELTEMIPEEEGSKFLDLGTASVLEGQLRSLMERVDELNQEAIKFNRYQQLVVRQQQDKHRWMVKRAQENAARAAKDETPLPEEDVNKLFKPHPVPPRLNPMIVAGQIDTYSQHISQFCSQSLAKLYLTQALQNAKEAKQNN

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit H family.

Keywords

Complete proteome   Cytoplasm   Initiation factor   Protein biosynthesis   Reference proteome  

Feature

chain  Eukaryotic translation initiation factor 3 subunit H

Uniprot

Q9GV27   A0A1E1WPX3   A0A3G1T1C4   A0A194R3P4   A0A2H1UZY3   A0A2A4IYS8   + More
I4DRN5   A0A212EVU9   I4DIL7   G9D575   D6WLC1   A0A1Y1LX35   N6TEL1   J3JU24   A0A1W4WHS2   A0A0T6AXV8   A0A0C9R6Q5   A0A026WCF4   E9J588   A0A0J7NEK3   E2ADS1   A0A151WMF0   A0A151I6U1   A0A195E6E4   F4WPE6   A0A195B164   A0A0M8ZU04   A0A195EVE5   A0A158NQZ5   E2BN26   A0A2J7RPF4   A0A182PU48   A0A182NF67   U5EX90   A0A023EQ18   A0A067QXC0   A0A182R6G8   A0A182V024   A0A182KUC6   A0A182UAP1   A0A182XKV5   A0A182I590   Q7PVR3   A0A182Y9U5   A0A182T3S3   A0A182KEY5   A0A084WQN8   A0A2M4BTK9   A0A182Q3J2   A0A182WH90   A0A2M4A5E4   W5JBH2   A0A182F4P1   B0WDA9   A0A2M4A5V8   Q170C2   A0A182M7S8   A0A2A3ECM7   A0A1Q3F7R7   A0A2M3YZZ6   A0A0L7R307   T1E9I6   T1EA44   A0A1L8DSD1   A0A0K8TRM7   A0A1B0D1A8   E0VY38   A0A336K718   A0A1B6GUQ5   W8B7X1   A0A1B6HFG6   A0A034W9W1   A0A2J7RPF6   A0A0C9R0L0   A0A0K8UGH3   T1PFF4   A0A1I8P3J4   A0A1J1IL44   A0A0A1WX06   A0A1L8EH75   A0A0L0CD09   A0A1L8EHF3   A0A069DSN6   A0A232EW51   K7IS46   A0A023F9R7   A0A0P4VS10   R4G3Y8   A0A023EP86   A0A0A9W0E1   A0A1A9WJN7   A0A224XFU4   A0A1A9ZNK1   A0A1B6GLR4   A0A1A9XJ65   A0A1B0BKR1   A0A182JF81   D3TS37   A0A1A9USH8   A0A1B0FMX2  

Pubmed

11222941    26354079    22651552    22118469    21967427    18362917    + More
19820115    28004739    23537049    22516182    24508170    30249741    21282665    20798317    21719571    21347285    24945155    24845553    20966253    12364791    25244985    24438588    20920257    23761445    17510324    17204158    26369729    20566863    24495485    25348373    25315136    25830018    26108605    26334808    28648823    20075255    25474469    27129103    25401762    26823975    20353571   

EMBL

AB041635    GDQN01002026    JAT89028.1    MG846927    AXY94779.1    KQ460855    + More
KPJ11860.1    ODYU01000050    SOQ34163.1    NWSH01004947    PCG64568.1    AK405201    BAM20575.1    AGBW02012119    OWR45613.1    AK401135    BAM17757.1    JF777478    AEU11823.1    KQ971343    EFA04093.1    GEZM01048083    GEZM01048082    JAV76635.1    APGK01040590    KB740984    KB632357    ENN76178.1    ERL93454.1    BT126736    AEE61698.1    LJIG01022563    KRT79906.1    GBYB01003650    JAG73417.1    KK107273    QOIP01000003    EZA53755.1    RLU24598.1    GL768124    EFZ12016.1    LBMM01006083    KMQ90950.1    GL438820    EFN68433.1    KQ982944    KYQ48987.1    KQ978459    KYM93811.1    KQ979608    KYN20447.1    GL888243    EGI64041.1    KQ976691    KYM77944.1    KQ435885    KOX69593.1    KQ981965    KYN31867.1    ADTU01023713    GL449382    EFN82930.1    NEVH01001361    PNF42709.1    GANO01001055    JAB58816.1    GAPW01002463    JAC11135.1    KK853138    KDR10780.1    APCN01003837    AAAB01008984    ATLV01025642    KE525396    KFB52532.1    GGFJ01007202    MBW56343.1    AXCN02000825    GGFK01002611    MBW35932.1    ADMH02001962    ETN60195.1    DS231895    GGFK01002873    MBW36194.1    CH477476    DQ440248    AXCM01005426    KZ288295    PBC28959.1    GFDL01011517    JAV23528.1    GGFM01001089    MBW21840.1    KQ414663    KOC65265.1    GAMD01001312    JAB00279.1    GAMD01001333    JAB00258.1    GFDF01004800    JAV09284.1    GDAI01000584    JAI17019.1    AJVK01002521    DS235843    EEB18294.1    UFQS01000134    UFQT01000134    SSX00257.1    SSX20637.1    GECZ01003654    JAS66115.1    GAMC01013417    JAB93138.1    GECU01034331    JAS73375.1    GAKP01008389    JAC50563.1    PNF42708.1    GBYB01006462    JAG76229.1    GDHF01026557    JAI25757.1    KA647512    AFP62141.1    CVRI01000054    CRL00482.1    GBXI01017268    GBXI01011344    JAC97023.1    JAD02948.1    GFDG01000771    JAV18028.1    JRES01000536    KNC30318.1    GFDG01000770    JAV18029.1    GBGD01002143    JAC86746.1    NNAY01001922    OXU22563.1    GBBI01000577    JAC18135.1    GDKW01001900    JAI54695.1    ACPB03003016    GAHY01001805    JAA75705.1    GAPW01002803    JAC10795.1    GBHO01042305    GBRD01006780    GDHC01020811    JAG01299.1    JAG59041.1    JAP97817.1    GFTR01005080    JAW11346.1    GECZ01006377    JAS63392.1    JXJN01015994    EZ424239    ADD20515.1    CCAG010018035   

Proteomes

UP000005204    UP000053240    UP000218220    UP000007151    UP000007266    UP000019118    + More
UP000030742    UP000192223    UP000053097    UP000279307    UP000036403    UP000000311    UP000075809    UP000078542    UP000078492    UP000007755    UP000078540    UP000053105    UP000078541    UP000005205    UP000008237    UP000235965    UP000075885    UP000075884    UP000027135    UP000075900    UP000075903    UP000075882    UP000075902    UP000076407    UP000075840    UP000007062    UP000076408    UP000075901    UP000075881    UP000030765    UP000075886    UP000075920    UP000000673    UP000069272    UP000002320    UP000008820    UP000075883    UP000242457    UP000053825    UP000092462    UP000009046    UP000095301    UP000095300    UP000183832    UP000037069    UP000215335    UP000002358    UP000015103    UP000091820    UP000092445    UP000092443    UP000092460    UP000075880    UP000078200    UP000092444   

PRIDE

Q9GV27    Q7PVR3    B0WDA9    Q170C2   

Pfam

PF01398   JAB        + More
PF00271   Helicase_C
PF00270   DEAD
PF15990   UPF0767

Interpro

IPR027524   eIF3h        + More
IPR037518   MPN       
IPR000555   JAMM/MPN+_dom       
IPR014001   Helicase_ATP-bd       
IPR000629   RNA-helicase_DEAD-box_CS       
IPR001650   Helicase_C       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR027417   P-loop_NTPase       
IPR031933   UPF0767       

SUPFAM

SSF52540   SSF52540       

CDD

cd08065  MPN_eIF3h
cd00079  HELICc

ProteinModelPortal

Q9GV27   A0A1E1WPX3   A0A3G1T1C4   A0A194R3P4   A0A2H1UZY3   A0A2A4IYS8   + More
I4DRN5   A0A212EVU9   I4DIL7   G9D575   D6WLC1   A0A1Y1LX35   N6TEL1   J3JU24   A0A1W4WHS2   A0A0T6AXV8   A0A0C9R6Q5   A0A026WCF4   E9J588   A0A0J7NEK3   E2ADS1   A0A151WMF0   A0A151I6U1   A0A195E6E4   F4WPE6   A0A195B164   A0A0M8ZU04   A0A195EVE5   A0A158NQZ5   E2BN26   A0A2J7RPF4   A0A182PU48   A0A182NF67   U5EX90   A0A023EQ18   A0A067QXC0   A0A182R6G8   A0A182V024   A0A182KUC6   A0A182UAP1   A0A182XKV5   A0A182I590   Q7PVR3   A0A182Y9U5   A0A182T3S3   A0A182KEY5   A0A084WQN8   A0A2M4BTK9   A0A182Q3J2   A0A182WH90   A0A2M4A5E4   W5JBH2   A0A182F4P1   B0WDA9   A0A2M4A5V8   Q170C2   A0A182M7S8   A0A2A3ECM7   A0A1Q3F7R7   A0A2M3YZZ6   A0A0L7R307   T1E9I6   T1EA44   A0A1L8DSD1   A0A0K8TRM7   A0A1B0D1A8   E0VY38   A0A336K718   A0A1B6GUQ5   W8B7X1   A0A1B6HFG6   A0A034W9W1   A0A2J7RPF6   A0A0C9R0L0   A0A0K8UGH3   T1PFF4   A0A1I8P3J4   A0A1J1IL44   A0A0A1WX06   A0A1L8EH75   A0A0L0CD09   A0A1L8EHF3   A0A069DSN6   A0A232EW51   K7IS46   A0A023F9R7   A0A0P4VS10   R4G3Y8   A0A023EP86   A0A0A9W0E1   A0A1A9WJN7   A0A224XFU4   A0A1A9ZNK1   A0A1B6GLR4   A0A1A9XJ65   A0A1B0BKR1   A0A182JF81   D3TS37   A0A1A9USH8   A0A1B0FMX2  

PDB

6FEC     E-value=2.49341e-81,     Score=768

KEGG

692388    K03247 translation initiation factor 3 subunit H | (RefSeq) eIF3h, En10; eukaryotic translation init

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0016282   GO:0005852   GO:0003743   GO:0001732   GO:0033290   GO:0042788   GO:0005829   GO:0008237   GO:0005524   GO:0008233   GO:0005737   GO:0005515   GO:0006470   GO:0008138   GO:0006370   GO:0006397   GO:0004651   GO:0005634  

PANTHER

PTHR10410:SF3  

Subcellular location

Cytoplasm  

Length:

337

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01378

Exp number, first 60 AAs:

0.00037

Total prob of N-in:

0.07352

outside

1  -  337

 

 

Pi

215.616028

Theta

164.247884

Tajima's D

0.208205

CLR

0.138204

CSRT

0.429228538573071

Interpretation

Uncertain