Gene
KWMTBOMO01699
Pre Gene Modal
BGIBMGA006028
Annotation
PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_15_[Bombyx_mori]
Full name
Mediator of RNA polymerase II transcription subunit 15
Alternative Name
Mediator complex subunit 15
Location in the cell
Nuclear Reliability : 3.532
Sequence
CDS
ATGGCGTCAGACGACAATAACTGGAGAACACAGTCATTTCGGCAAAACGTTGTTTCTAAAATCGAGGAAGCAATACAGCGCTCCGGTATGCAGGTCGCTCGTAACAGCAGTGAGATGGAGACTCATGTGTTCTTAAAGGCCAAAAACAGAGATGAGTACATGAATATGGTAGCAAAACTCATTCTGCATGTAAGAGAAATGTCACAACCAAAGCAAAATCAAGGCCAACCAAATATGCAAGTGCAAAATCAGAACCAAAGTGGTCCTTCTACACAAGTACAACCCCAACAGGGACAAGCCCCTCAAGGTCCTAATAGCCAGACTGGCTTAGCCCCCGACCCTATAAATGCATTACAGACGCTCGCATCTCAAGGATCTCGAAACCAGATGATGAATATGGGACCTCAAGGCCAAATGCAACAACAAAACGTTATGCAGACACAAATGGGGGGCATGCAGTCTCAGTTGGGTCAAACGGGTCCCATAGTGTCTCAGGGACCTCAAGCCCAAACCGCTACTAACCTGCTTCAAACATTAAACCAAAGACCACAAATGAATATGCCCATGCAAAACAAACTTGCTGGTTCAATGGGCATGGTCGGAAATCAGGGTCAAATGGGCAACAATATGGGCATGGGAGGCATGGGAAATCCTATGGGCAGTCAGCTGCAGAATCAGCTTGCTGGACCCAGCATGCAGGGTCAGATGATGCAGAATATGTCCATGTCTAATAATATGGCAGTGCCTATGAGTGGTGCTAATACCATGGTGGGTCAGATGCCATGTAACCAAGTGGGTATGGGCGGTCAGATGCCACCCAACAATATGCAAGGGCAAATGTCTGGGCAAATGGTGGGAGGAATGGGAAATAATCAGATGGTGGGTATGAACATGGGCCACATGCAGGGCAGGGTGCAAGGCAAGCAGGAGGTGGGCATGCTGGGCGCGGGGTACTCGCGAGGCCCGCCGCCCGCACAGTTCCTGAGGCAGAGCCCCTCGCCCTCTGCACCCTCACCGGGCATGCCCGGACCCAGTCCCGTCTCCATGGGAGTGATGGCCAACACTATGCCATCCCCAATGTCGAGTCTGGGCGGGCTGGCGGCCTGCGGGGGAAGCCCCTCGCCCTCCGCCCCCACGCACCTCGCGCATCACGTCTCACAGCAACAGAGGAGCGTGGGTATGGGCATGGTGCAGTCTCCGTCCCCGTCCCTCAACACCCCGCAGGCGGCGCTGGGGGCGGGGTCCCCGGGCGGCGAGGAGGCCGCCTACAGGGAGAAGGTCCGCCAGCTCTCCAAGTACATCGAGCCATTACGGCGCATGGTGCACAGGATGGTCAGCGAGGGCGAGAATGTGGAGAAGTTGAAGAAGATGAAGAACCTACTGGACATCTTGTCGAATCCTAACAAAAGGATAACTTTGGAGACGCTCATCAAGTGTGAGGTCGTGCTCGAGAAGTTGGACTTCAAACGAAGCGAAGGGGTCGTGGTGGGACTGCCGGGGTCCGGGAAGGAGCAAATAGTGAACCCGTTGCTGGAGGTCGTCAACAACTGCCTGCAGTCGCCGCTGGCTAACCACACGCTCAAGAGAACCTTCGGGTCCACCCTGGACGCTCTAAATGGACCAGAGATAAAGAACGTGCCGCCGCCGTACAAGGCGCCGAAGATGGCGGAGCCCGAGATGGAGATACCCGACGTGCTGCAGGGGGAAATTGCCAGGCTGGACTCCAGGTTCAAGGTGTCGCTGGAGTCGCTGCAGCTGGGCGGCGGCGGGCTGTGGCTGGTGGCGCAGCTGGACGACGCGCGGCTGCCGTGCGCGTGCTCCGTGCACGTGTCCGTGCCGCGCGACTACCCCGCCGCGCCCCCCGCGCTGCTGCGCCGCCCCCCCCGCGCCCGCGCCGCGCACTCCGCCTTCCTGCACCGCGTCGAGCGCGCCATGGACGCCCGCTGCGCCAGGCTACCAAAAAGCTGTTCTGTGGGCCAACTCCTGGACGCGTGGGAGATGAGCGTGCGGCAGGCGTGCGCACCCAACCCGGTCGAGTACCTGCCGGTCCCCGCGCTCGGGCTCTAA
Protein
MASDDNNWRTQSFRQNVVSKIEEAIQRSGMQVARNSSEMETHVFLKAKNRDEYMNMVAKLILHVREMSQPKQNQGQPNMQVQNQNQSGPSTQVQPQQGQAPQGPNSQTGLAPDPINALQTLASQGSRNQMMNMGPQGQMQQQNVMQTQMGGMQSQLGQTGPIVSQGPQAQTATNLLQTLNQRPQMNMPMQNKLAGSMGMVGNQGQMGNNMGMGGMGNPMGSQLQNQLAGPSMQGQMMQNMSMSNNMAVPMSGANTMVGQMPCNQVGMGGQMPPNNMQGQMSGQMVGGMGNNQMVGMNMGHMQGRVQGKQEVGMLGAGYSRGPPPAQFLRQSPSPSAPSPGMPGPSPVSMGVMANTMPSPMSSLGGLAACGGSPSPSAPTHLAHHVSQQQRSVGMGMVQSPSPSLNTPQAALGAGSPGGEEAAYREKVRQLSKYIEPLRRMVHRMVSEGENVEKLKKMKNLLDILSNPNKRITLETLIKCEVVLEKLDFKRSEGVVVGLPGSGKEQIVNPLLEVVNNCLQSPLANHTLKRTFGSTLDALNGPEIKNVPPPYKAPKMAEPEMEIPDVLQGEIARLDSRFKVSLESLQLGGGGLWLVAQLDDARLPCACSVHVSVPRDYPAAPPALLRRPPRARAAHSAFLHRVERAMDARCARLPKSCSVGQLLDAWEMSVRQACAPNPVEYLPVPALGL
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subunit
Component of the Mediator complex.
Similarity
Belongs to the Mediator complex subunit 15 family.
Uniprot
EMBL
Proteomes
PRIDE
Pfam
PF09606 Med15
SUPFAM
SSF47040
SSF47040
ProteinModelPortal
PDB
2GUT
E-value=3.73944e-15,
Score=201
Ontologies
GO
Topology
Subcellular location
Nucleus
Length:
688
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.02222
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00212
outside
1 - 688
Population Genetic Test Statistics
Pi
165.654685
Theta
153.025388
Tajima's D
-0.4413
CLR
1.046519
CSRT
0.256437178141093
Interpretation
Uncertain
