Gene

KWMTBOMO01696

Pre Gene Modal

BGIBMGA006029

Annotation

PREDICTED:_heparin_sulfate_O-sulfotransferase_[Amyelois_transitella]

Location

Bomo_Chr4(-):1737431-1740888      View in EpiBrowser

Full name

Heparin sulfate O-sulfotransferase      

Location in the cell

Nuclear   Reliability : 2.128

CDS

ATGGAAGAGAATTATCGTAAATTAGAAATAAGATTAGCCCACCCAGGAATCGGATTAACGGAGTCTCGCCAGTTTCCTCTAAATAATGCGGACCAGACTGTCATTATATACAATAGGGTCCCGAAGACGGGGTCCACGAGCTTCGTGGGAATCGCGTACGATTTATGCAAGAGGAACAATTTTAAAGTGCTACATATCAACATTACCGCCAACAGACATATCATGTCGTTGAATAACCAATATAAATTTGCTCAGAATGTAACCACTTGGCATGATGTCAAACCTGCCCTATATCATGGGCATATGGCCTTCCTAAATTTTGAGAGATTAGGTACATCATCAAAACCCCTATTCATAAATTTAATAAGGAAACCATTGGACAGACTAGTTTCATATTATTACTTCCTACGCTACGGTGACAATTTCCGACCCCATTTGGTACGAAAGAAACATGGTGACAAAATGACATTTGATGAATGTGTTGAGAAGAGCCAGCCGGATTGTGACCCAAACAATATGTGGTTACAAGTGCCTTTTTTCTGTGGTCACGCTGCAGAGTGCTGGAAACCAGGCAACCATTGGGCTTTAGAACAAGCAAAGCACAACTTAGTCAACCACTACCTTTTGGTAGGAGTCACCGAGGAAATGCAGGACTTCATCACAGTACTCGAAGCCACTTTACCGCGCTTCTTCAAAGGGGCCACCGAGTATTACCTAAGCAGTAATAAGTCCCACCTACGGCAGACGAGCTCGAAAGTGGACCCGAGCCTGAAGACGGTCGAGAGGATTCAACAGTCGACCGTTTGGAAAATGGAAAATGAGCTTTATGAGTTTGCATTAGAACATTTTAAATTTGTGAAAAGGAAACTTTTAGTGAAGGAAGCAAACAATGTGGCTCAGATATATTTTTATGAGAAAATAAGACCTAAATGA

Protein

MEENYRKLEIRLAHPGIGLTESRQFPLNNADQTVIIYNRVPKTGSTSFVGIAYDLCKRNNFKVLHINITANRHIMSLNNQYKFAQNVTTWHDVKPALYHGHMAFLNFERLGTSSKPLFINLIRKPLDRLVSYYYFLRYGDNFRPHLVRKKHGDKMTFDECVEKSQPDCDPNNMWLQVPFFCGHAAECWKPGNHWALEQAKHNLVNHYLLVGVTEEMQDFITVLEATLPRFFKGATEYYLSSNKSHLRQTSSKVDPSLKTVERIQQSTVWKMENELYEFALEHFKFVKRKLLVKEANNVAQIYFYEKIRPK

Subunit

Homotrimer.

Similarity

Belongs to the sulfotransferase 3 family.

Keywords

Alternative splicing   Complete proteome   Disulfide bond   Glycoprotein   Golgi apparatus   Membrane   Reference proteome   Signal-anchor   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Heparin sulfate O-sulfotransferase
splice variant  In isoform S4.

Uniprot

A0A2A4JFF5   A0A2H1W6L3   A0A194PZQ9   A0A194RBF4   H9J937   A0A212FCC2   + More
A0A2W1BL67   A0A0K8TP20   A0A1Y1NAR3   A0A1B0Y0B6   A0A1S4F4P8   Q17FQ7   B4M966   A0A2J7QVT7   A0A067RNP2   E2C5N2   D6WJV8   A0A1Q3FB70   A0A1L8E4P5   A0A1L8E593   W8BM09   A0A087U5T2   A0A182YSP0   B4KK65   E2AC79   A0A182MW43   A0A0C9RGG6   A0A182W6Y7   A0A034W043   A0A182SPW5   A0A1B6C0H2   A0A0A1WSK7   A0A0K8V7F9   E0VPR1   A0A182JKZ9   A0A182RCQ8   B0WGK2   A0A1A9V7H3   A0A182GWJ3   A0A182QL53   A0A182JQG3   A0A026WUY6   Q29K51   A0A0M4E6I6   A0A084W834   A0A195ESL4   A0A195AT85   A0A1A9Z5N9   F4W7L0   A0A182WTY2   A0A182VJF8   A0A182HUJ8   A0A336MAC3   A0A158NPN7   A0A182UJM4   B4MYQ3   A0A0L0BU72   B4JP82   A0A182PPM9   A0A151WJ66   A0A232FCG7   Q7Q428   A0A2M4AUV4   A0A2M4AUP2   A0A182F2J1   K7ITS5   B3NM55   A0A1W4WYF9   A0A1B0BH17   A0A154PDL8   W5JK51   B3MK01   J3JYF7   A0A0N0BCJ5   A0A0L7R7E2   B4Q9Y1   A0A3B0JYH0   A0A1I8QBE3   B4PAY6   A0A088A780   P25722   P25722-2   B4I5V2   A0A1B6JKF4   A0A0A9VS21   A0A146LU86   A0A1S4EGM9   A0A3P9PHP7   A0A131XDT2   A0A195EM22   A0A1S3KC26   E9IY37   E9FUJ1   A0A3B5R5N7   A0A336N5V7   A0A3B3Y396   A0A3B3WFC0   A0A087X334   A0A3B3TXT1   A0A1A8QJ88  

EC Number

2.8.2.-

Pubmed

26354079    19121390    22118469    28756777    26369729    28004739    + More
17510324    17994087    24845553    20798317    18362917    19820115    24495485    25244985    25348373    25830018    20566863    26483478    24508170    30249741    15632085    24438588    21719571    21347285    26108605    28648823    12364791    14747013    17210077    20075255    20920257    23761445    22516182    22936249    17550304    1936954    10731132    12537572    12537569    25401762    26823975    28049606    21282665    21292972    23542700   

EMBL

NWSH01001783    PCG70153.1    ODYU01006354    SOQ48134.1    KQ459584    KPI98523.1    + More
KQ460644    KPJ13231.1    BABH01004468    AGBW02009207    OWR51381.1    KZ150052    PZC74384.1    GDAI01001690    JAI15913.1    GEZM01010621    JAV93970.1    KT000407    ANI86005.1    CH477269    EAT45367.1    CH940654    EDW57742.2    NEVH01009771    PNF32698.1    KK852514    KDR22215.1    GL452776    EFN76743.1    KQ971342    EFA04624.1    GFDL01010283    JAV24762.1    GFDF01000383    JAV13701.1    GFDF01000382    JAV13702.1    GAMC01006723    JAB99832.1    KK118321    KFM72721.1    CH933807    EDW11583.2    GL438428    EFN68973.1    AXCM01004769    GBYB01012205    GBYB01012207    JAG81972.1    JAG81974.1    GAKP01011447    JAC47505.1    GEDC01030300    JAS06998.1    GBXI01012889    JAD01403.1    GDHF01017626    JAI34688.1    DS235371    EEB15367.1    DS231927    EDS27031.1    JXUM01093395    JXUM01093396    KQ564054    KXJ72861.1    AXCN02000760    KK107105    QOIP01000011    EZA59476.1    RLU16804.1    CH379061    EAL33327.2    CP012523    ALC39971.1    ATLV01021355    KE525317    KFB46378.1    KQ981986    KYN31218.1    KQ976745    KYM75406.1    GL887844    EGI69883.1    APCN01002465    UFQT01000300    SSX22988.1    ADTU01022666    CH963913    EDW77242.1    JRES01001455    KNC22764.1    CH916372    EDV98712.1    KQ983049    KYQ47871.1    NNAY01000473    OXU28138.1    AAAB01008964    EAA12392.4    GGFK01011171    MBW44492.1    GGFK01011170    MBW44491.1    CH954179    EDV54655.1    JXJN01014109    JXJN01014110    KQ434869    KZC09348.1    ADMH02000888    ETN64752.1    CH902620    EDV32456.1    BT128283    AEE63243.1    KQ435916    KOX68798.1    KQ414642    KOC66753.1    CM000361    CM002910    EDX05511.1    KMY91014.1    OUUW01000010    SPP85482.1    CM000158    EDW90415.1    X60218    AE014134    AY058422    CH480822    EDW55758.1    GECU01008036    JAS99670.1    GBHO01045528    JAF98075.1    GDHC01008679    JAQ09950.1    GEFH01004256    JAP64325.1    KQ978730    KYN28972.1    GL766903    EFZ14513.1    GL732525    EFX88915.1    UFQT01002680    SSX33928.1    AYCK01017732    HAEG01012904    SBR93546.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000005204    UP000007151    UP000008820    + More
UP000008792    UP000235965    UP000027135    UP000008237    UP000007266    UP000054359    UP000076408    UP000009192    UP000000311    UP000075883    UP000075920    UP000075901    UP000009046    UP000075880    UP000075900    UP000002320    UP000078200    UP000069940    UP000249989    UP000075886    UP000075881    UP000053097    UP000279307    UP000001819    UP000092553    UP000030765    UP000078541    UP000078540    UP000092445    UP000007755    UP000076407    UP000075903    UP000075840    UP000005205    UP000075902    UP000007798    UP000037069    UP000001070    UP000075885    UP000075809    UP000215335    UP000007062    UP000069272    UP000002358    UP000008711    UP000192223    UP000092460    UP000076502    UP000000673    UP000007801    UP000053105    UP000053825    UP000000304    UP000268350    UP000095300    UP000002282    UP000005203    UP000000803    UP000001292    UP000079169    UP000242638    UP000078492    UP000085678    UP000000305    UP000002852    UP000261480    UP000028760    UP000261500   

PRIDE

H9J937    P25722   

Pfam

PF03567   Sulfotransfer_2        + More
PF01217   Clat_adaptor_s
PF04042   DNA_pol_E_B

Interpro

IPR005331   Sulfotransferase        + More
IPR007734   Heparan_SO4_2-O-STrfase       
IPR027417   P-loop_NTPase       
IPR022775   AP_mu_sigma_su       
IPR011012   Longin-like_dom_sf       
IPR007185   DNA_pol_a/d/e_bsu       

SUPFAM

SSF52540   SSF52540        + More
SSF64356   SSF64356       

ProteinModelPortal

A0A2A4JFF5   A0A2H1W6L3   A0A194PZQ9   A0A194RBF4   H9J937   A0A212FCC2   + More
A0A2W1BL67   A0A0K8TP20   A0A1Y1NAR3   A0A1B0Y0B6   A0A1S4F4P8   Q17FQ7   B4M966   A0A2J7QVT7   A0A067RNP2   E2C5N2   D6WJV8   A0A1Q3FB70   A0A1L8E4P5   A0A1L8E593   W8BM09   A0A087U5T2   A0A182YSP0   B4KK65   E2AC79   A0A182MW43   A0A0C9RGG6   A0A182W6Y7   A0A034W043   A0A182SPW5   A0A1B6C0H2   A0A0A1WSK7   A0A0K8V7F9   E0VPR1   A0A182JKZ9   A0A182RCQ8   B0WGK2   A0A1A9V7H3   A0A182GWJ3   A0A182QL53   A0A182JQG3   A0A026WUY6   Q29K51   A0A0M4E6I6   A0A084W834   A0A195ESL4   A0A195AT85   A0A1A9Z5N9   F4W7L0   A0A182WTY2   A0A182VJF8   A0A182HUJ8   A0A336MAC3   A0A158NPN7   A0A182UJM4   B4MYQ3   A0A0L0BU72   B4JP82   A0A182PPM9   A0A151WJ66   A0A232FCG7   Q7Q428   A0A2M4AUV4   A0A2M4AUP2   A0A182F2J1   K7ITS5   B3NM55   A0A1W4WYF9   A0A1B0BH17   A0A154PDL8   W5JK51   B3MK01   J3JYF7   A0A0N0BCJ5   A0A0L7R7E2   B4Q9Y1   A0A3B0JYH0   A0A1I8QBE3   B4PAY6   A0A088A780   P25722   P25722-2   B4I5V2   A0A1B6JKF4   A0A0A9VS21   A0A146LU86   A0A1S4EGM9   A0A3P9PHP7   A0A131XDT2   A0A195EM22   A0A1S3KC26   E9IY37   E9FUJ1   A0A3B5R5N7   A0A336N5V7   A0A3B3Y396   A0A3B3WFC0   A0A087X334   A0A3B3TXT1   A0A1A8QJ88  

PDB

3F5F     E-value=5.25974e-106,     Score=981

KEGG

101736578    K02513 heparan sulfate 2-O-sulfotransferase HS2ST1 [EC:2.8.2.-] | (RefSeq) heparin sulfate O-sulfotr

PATHWAY

00534    Glycosaminoglycan biosynthesis - heparan sulfate / heparin - Bombyx mori (domestic silkworm)

GO

GO:0008146   GO:0016021   GO:0004394   GO:0015015   GO:0015014   GO:0015012   GO:0007424   GO:0015031   GO:0000139   GO:0007165   GO:0003677   GO:0006260   GO:0003887   GO:0019205   GO:0006355   GO:0006508   GO:0006811   GO:0016020   GO:0005515   GO:0003779  

PANTHER

PTHR12129  

Subcellular location

Golgi apparatus membrane  

Length:

310

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00807999999999996

Exp number, first 60 AAs:

0.00567

Total prob of N-in:

0.05432

outside

1  -  310

 

 

Pi

193.06916

Theta

204.07914

Tajima's D

-0.165932

CLR

172.583034

CSRT

0.330083495825209

Interpretation

Uncertain