Pre Gene Modal
BGIBMGA006109
Annotation
chromobox-like_protein_5_[Bombyx_mori]
Full name
Chromobox protein homolog 5
Alternative Name
Heterochromatin protein 1 homolog alpha
Antigen p25
Antigen p25
Location in the cell
Nuclear Reliability : 3.918
Sequence
CDS
ATGGGTAAAAAAGAGAAGAAAACGGAGACCAGTGAAGCATCGAGCGAGGAAGAATATGTCGTGGAGAAAGTTCTTAACAAACGTACAGTCAAAGGAAAGATCCAATATTTATTGAAATGGAAAGGCTATAAGGAGGAAGAGAGTACTTGGGAGCCTGTTGAAAACTTAGACTGTGAGGAACTGATTAAAACTTTTGAAGAAAATAGGAAAGAAAAAGAGAAATCTTCAAAAAAACCTGAGGACCGTGCTAAGAAGCGAGTCCGTGAATCAAGTGAGGAGACCAGTTCTGGTAGGAAAGGTCGGGGGGCAAGTGTTTCGTCGGCTGACGAACCAAAAGAGAGCAAAAGGGAAAGAAAGGAAGAAAAAAGCAAAACTGGCTTTGATAAAGGACTCAAAGCTGAGAAAATTATAGGCGCTTCAGATGCTACCGGTGAACTAATGTTTTTGATCAAATGGACAGACTCTGACGAGGCTGAACTAGTTCCAGCTAAAGTAGCTAATGTTAAATGCCCGCAGCAAGTAATAGCGTTTTATGAAGAAAGGCTAACTTGGCACACGCCATCCGAATCTGAATAA
Protein
MGKKEKKTETSEASSEEEYVVEKVLNKRTVKGKIQYLLKWKGYKEEESTWEPVENLDCEELIKTFEENRKEKEKSSKKPEDRAKKRVRESSEETSSGRKGRGASVSSADEPKESKRERKEEKSKTGFDKGLKAEKIIGASDATGELMFLIKWTDSDEAELVPAKVANVKCPQQVIAFYEERLTWHTPSESE
Summary
Description
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Subunit
Interacts directly with ATRX, CHAF1A, LBR, NIPBL, SP100 and STAM2 via the chromoshadow domain. Can interact directly with CBX3 via the chromoshadow domain. Interacts with histone H3 methylated at 'Lys-9'. Interacts with BAHD1, SETDB1, MIS12 and DSN1. Interacts with POGZ; POGZ and PXVXL motif-containing proteins such as INCENP and TRIM28 compete for interaction with CBX5. Interacts with INCENP. Interacts with CHAMP1 (By similarity). Interacts directly with TRIM28 via the chromoshadow domain (PubMed:8978696). Interacts with KMT5B and KMT5C (PubMed:15145825). Interacts with HP1BP3 and TRIM24 (PubMed:8978696). May form homodimers (PubMed:8978696). Interacts with PRR14 (via N-terminus) (By similarity). Interacts with RRP1B (By similarity). Interacts with HNRNPU (via C-terminus); this interaction is, at least in part, RNA-dependent (By similarity). Interacts with LRIF1 (via PxVxL motif) (By similarity).
Interacts with KMT5B and KMT5C (By similarity). Interacts with HP1BP3 (PubMed:20042602). Interacts directly with ATRX, CHAF1A, LBR, NIPBL, SP100, STAM2 and TRIM28 via the chromoshadow domain (PubMed:15882967, PubMed:9169472). Can interact directly with CBX3 via the chromoshadow domain (PubMed:9169472). Interacts with histone H3 methylated at 'Lys-9' (PubMed:11242053, PubMed:21047797). Interacts with BAHD1, MIS12 and DSN1 (PubMed:15502821, PubMed:19666599). Interacts with POGZ; POGZ and PXVXL motif-containing proteins such as INCENP and TRIM28 compete for interaction with CBX5 (PubMed:20562864, PubMed:20850016, PubMed:21346195). Interacts with INCENP and TRIM24 (PubMed:11313457). Interacts with CHAMP1 (PubMed:20850016). Interacts with PRR14 (via N-terminus) (PubMed:25906157). Interacts with RRP1B (PubMed:19710015). Interacts with HNRNPU (via C-terminus); this interaction is, at least in part, RNA-dependent (PubMed:19617346). Interacts with LRIF1 (via PxVxL motif) (PubMed:23542155).
(Microbial infection) Interacts with JC virus agnoprotein; this interaction induces the dissociation of CBX5 from LBR, resulting in destabilization of the nuclear envelope.
Interacts with KMT5B and KMT5C (By similarity). Interacts with HP1BP3 (PubMed:20042602). Interacts directly with ATRX, CHAF1A, LBR, NIPBL, SP100, STAM2 and TRIM28 via the chromoshadow domain (PubMed:15882967, PubMed:9169472). Can interact directly with CBX3 via the chromoshadow domain (PubMed:9169472). Interacts with histone H3 methylated at 'Lys-9' (PubMed:11242053, PubMed:21047797). Interacts with BAHD1, MIS12 and DSN1 (PubMed:15502821, PubMed:19666599). Interacts with POGZ; POGZ and PXVXL motif-containing proteins such as INCENP and TRIM28 compete for interaction with CBX5 (PubMed:20562864, PubMed:20850016, PubMed:21346195). Interacts with INCENP and TRIM24 (PubMed:11313457). Interacts with CHAMP1 (PubMed:20850016). Interacts with PRR14 (via N-terminus) (PubMed:25906157). Interacts with RRP1B (PubMed:19710015). Interacts with HNRNPU (via C-terminus); this interaction is, at least in part, RNA-dependent (PubMed:19617346). Interacts with LRIF1 (via PxVxL motif) (PubMed:23542155).
(Microbial infection) Interacts with JC virus agnoprotein; this interaction induces the dissociation of CBX5 from LBR, resulting in destabilization of the nuclear envelope.
Keywords
3D-structure
Acetylation
Centromere
Chromosome
Complete proteome
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation
Direct protein sequencing
Host-virus interaction
Feature
chain Chromobox protein homolog 5
Uniprot
H9J9B7
Q1HPP1
A0A2W1BHW0
R4IT63
A0A2A4J9V2
A0A1E1W5D8
+ More
A0A2H1X0H0 I4DNU2 A0A194R6F7 A0A212EWJ8 S4PWP7 A0A2J7RIV1 A0A194Q684 H3ARE6 B2RYU7 Q61686 Q6E6J6 A0A1U8BT65 A0A212FMI2 A0A194RSL3 A0A1J1J077 A0A2K5CRQ0 A0A2Y9FKU5 A0A341ARS8 A0A2U4CBG8 A0A340Y2E2 A0A383ZXC3 A0A2Y9N3J9 A0A2H1V4I1 A0A1U8BGU0 W5N7D5 S9Y6D8 Q7ZVR4 F1QM86 F0J9Z4 H2Q639 A0A2J8UIM0 E2AQB3 Q52T68 G1KFI8 A0A1A6HHC0 H0X953 C8BKD4 K9J4Y6 K7FA46 A0A1B0DE28 G5BID8 A0A250YBI4 A0A091CSL1 I3MNC5 A0A2K6ECP8 A0A2K5WBV7 G3QCU2 G1S7F7 L8I9B4 A0A0D9QZG1 A0A2R9A4K7 A0A2I3LLL9 A0A2K6QYW9 A0A2K5MPW2 F2Z4J7 L8Y296 A0A212DF96 A0A2K6G9A8 F2Z5T3 A0A2K5QBE6 F6UM66 A0A2K6THI9 K7AP88 F7C841 F7IG39 A0A1U7TLR6 V9HWG0 P45973 A0A286XDM7 G3W7D7 S4RV78 Q28HD9 I4DN34 A0A1A8DBS8 F6QIP4 A0A3P8XU08 F6T174 Q6GLP2 H3B1R7 A0A1A8CR17 A0A1A8IK97 A0A1A8B216 D2HM50 A0A1A8FL99 A0A224YLU2 A0A131YEL4 A0A2Y9L165 E2QYK6 A0A2Y9GXB4 M3Y376 A0A2U3WCN4 A0A2U3XBA2 A0A2I2U2I6 A0A384D763
A0A2H1X0H0 I4DNU2 A0A194R6F7 A0A212EWJ8 S4PWP7 A0A2J7RIV1 A0A194Q684 H3ARE6 B2RYU7 Q61686 Q6E6J6 A0A1U8BT65 A0A212FMI2 A0A194RSL3 A0A1J1J077 A0A2K5CRQ0 A0A2Y9FKU5 A0A341ARS8 A0A2U4CBG8 A0A340Y2E2 A0A383ZXC3 A0A2Y9N3J9 A0A2H1V4I1 A0A1U8BGU0 W5N7D5 S9Y6D8 Q7ZVR4 F1QM86 F0J9Z4 H2Q639 A0A2J8UIM0 E2AQB3 Q52T68 G1KFI8 A0A1A6HHC0 H0X953 C8BKD4 K9J4Y6 K7FA46 A0A1B0DE28 G5BID8 A0A250YBI4 A0A091CSL1 I3MNC5 A0A2K6ECP8 A0A2K5WBV7 G3QCU2 G1S7F7 L8I9B4 A0A0D9QZG1 A0A2R9A4K7 A0A2I3LLL9 A0A2K6QYW9 A0A2K5MPW2 F2Z4J7 L8Y296 A0A212DF96 A0A2K6G9A8 F2Z5T3 A0A2K5QBE6 F6UM66 A0A2K6THI9 K7AP88 F7C841 F7IG39 A0A1U7TLR6 V9HWG0 P45973 A0A286XDM7 G3W7D7 S4RV78 Q28HD9 I4DN34 A0A1A8DBS8 F6QIP4 A0A3P8XU08 F6T174 Q6GLP2 H3B1R7 A0A1A8CR17 A0A1A8IK97 A0A1A8B216 D2HM50 A0A1A8FL99 A0A224YLU2 A0A131YEL4 A0A2Y9L165 E2QYK6 A0A2Y9GXB4 M3Y376 A0A2U3WCN4 A0A2U3XBA2 A0A2I2U2I6 A0A384D763
Pubmed
19121390
28756777
22651552
26354079
22118469
23622113
+ More
9215903 15489334 15057822 15632090 22673903 8978696 11107181 16141072 10562550 15145825 16452087 19144319 21183079 15252244 21804562 23149746 23594743 21362191 16136131 20798317 17486619 20809919 17381049 21993625 28087693 22398555 22751099 22722832 25362486 19393038 23385571 29294181 30723633 19892987 17431167 22002653 25319552 25243066 11181995 8505380 14702039 8663349 9169472 10460410 11313457 11242053 15502821 15882967 15864296 15899859 17081983 18691976 18669648 19617346 19710015 19783980 19666599 19690332 20850016 19880879 25750265 20562864 20498703 20068231 21269460 21346195 21406692 22814378 23186163 23542155 24275569 25218447 25906157 25772364 25755297 28112733 21047797 20042602 21993624 21709235 20431018 25069045 18464734 20010809 28797301 26830274 16341006 17975172 24813606
9215903 15489334 15057822 15632090 22673903 8978696 11107181 16141072 10562550 15145825 16452087 19144319 21183079 15252244 21804562 23149746 23594743 21362191 16136131 20798317 17486619 20809919 17381049 21993625 28087693 22398555 22751099 22722832 25362486 19393038 23385571 29294181 30723633 19892987 17431167 22002653 25319552 25243066 11181995 8505380 14702039 8663349 9169472 10460410 11313457 11242053 15502821 15882967 15864296 15899859 17081983 18691976 18669648 19617346 19710015 19783980 19666599 19690332 20850016 19880879 25750265 20562864 20498703 20068231 21269460 21346195 21406692 22814378 23186163 23542155 24275569 25218447 25906157 25772364 25755297 28112733 21047797 20042602 21993624 21709235 20431018 25069045 18464734 20010809 28797301 26830274 16341006 17975172 24813606
EMBL
BABH01004434
DQ443361
ABF51450.1
KZ150155
PZC72797.1
JQ744279
+ More
AGC39045.1 NWSH01002366 PCG68458.1 GDQN01008895 GDQN01005081 JAT82159.1 JAT85973.1 ODYU01012492 SOQ58829.1 AK403140 KQ459584 BAM19582.1 KPI98508.1 KQ460644 KPJ13247.1 AGBW02011959 OWR45865.1 GAIX01006418 JAA86142.1 NEVH01003069 PNF40759.1 KQ459582 KPI98920.1 AFYH01023021 AFYH01023022 AABR07058936 BC166908 BC168739 CH474035 AAI66908.1 AAI68739.1 EDL86794.1 X99641 AF216290 AK008792 AK018349 AK030366 AK030442 AK032975 AK019198 BC004707 AY548740 AY550262 JH002588 AAT40865.1 AAT42188.1 EGW11777.1 AGBW02007651 OWR54955.1 KQ459700 KPJ20335.1 CVRI01000065 CRL05799.1 ODYU01000635 SOQ35748.1 AHAT01031041 AHAT01031042 KB016878 EPY82951.1 CR450718 BC045443 BC075782 BC165019 AAH45443.1 AAH75782.1 AAI65019.1 AL953901 BK007695 DAA34563.1 AACZ04012940 ABGA01242736 ABGA01242737 ABGA01242738 ABGA01242739 NDHI03003457 PNJ45073.1 PNJ45074.1 PNJ45075.1 PNJ45076.1 GL441721 EFN64371.1 AY962101 AAX94036.1 LZPO01030506 OBS77350.1 AAQR03076677 AAQR03076678 AAQR03076679 AAQR03076680 AAQR03076681 AMGL01080243 AMGL01080244 GQ221053 ACV04833.1 GABZ01002661 JAA50864.1 AGCU01131594 AGCU01131595 AGCU01131596 AGCU01131597 AJVK01032485 JH170425 EHB09049.1 GFFW01003797 JAV40991.1 KN124398 KFO21292.1 AGTP01037516 AGTP01037517 AGTP01037518 AQIA01011083 CABD030083745 CABD030083746 ADFV01002626 ADFV01002627 ADFV01002628 ADFV01002629 JH881897 ELR51787.1 AQIB01022967 AQIB01022968 AQIB01022969 AQIB01022970 AJFE02022267 AJFE02022268 AJFE02022269 AHZZ02002230 AHZZ02002231 KB367542 ELV10488.1 MKHE01000003 OWK16923.1 AEMK02000028 DQIR01153398 GACC01000491 HDB08875.1 JAA74093.1 JL616029 AEH58236.1 GABC01009742 GABC01009741 GABC01009740 GABC01009739 GABC01009738 GABF01007676 GABD01008954 GABD01008951 GABE01007265 GABE01007264 GABE01007263 NBAG03000092 JAA01600.1 JAA14469.1 JAA24146.1 JAA37474.1 PNI89882.1 PNI89883.1 PNI89884.1 PNI89885.1 JSUE03006878 JSUE03006879 JU319960 JU319961 JU332138 JU332139 JU474940 JV043983 CM001263 AFE63716.1 AFH31744.1 AFI34054.1 EHH20800.1 GAMT01010071 GAMS01007853 GAMS01007852 GAMS01007851 GAMR01000100 GAMR01000092 GAMQ01006380 GAMP01001777 GAMP01001776 JAB01790.1 JAB15283.1 JAB33832.1 JAB35471.1 JAB50978.1 EU794599 CH471054 ACJ13653.1 EAW96760.1 S62077 L07515 AK313506 BC006821 U26311 AAKN02014963 AEFK01204204 CR760924 CAJ82321.1 AK402702 BAM19324.1 HAEA01003265 SBQ31745.1 AAMC01075965 BC074418 AAH74418.1 AFYH01066990 AFYH01066991 HADZ01017552 SBP81493.1 HAED01011315 HAEE01015363 SBQ97613.1 HADY01023007 HAEJ01001635 SBP61492.1 ACTA01139502 GL193035 EFB17765.1 HAEB01013091 SBQ59618.1 GFPF01006769 MAA17915.1 GEDV01011625 JAP76932.1 AAEX03014967 AEYP01084409 AANG04001751
AGC39045.1 NWSH01002366 PCG68458.1 GDQN01008895 GDQN01005081 JAT82159.1 JAT85973.1 ODYU01012492 SOQ58829.1 AK403140 KQ459584 BAM19582.1 KPI98508.1 KQ460644 KPJ13247.1 AGBW02011959 OWR45865.1 GAIX01006418 JAA86142.1 NEVH01003069 PNF40759.1 KQ459582 KPI98920.1 AFYH01023021 AFYH01023022 AABR07058936 BC166908 BC168739 CH474035 AAI66908.1 AAI68739.1 EDL86794.1 X99641 AF216290 AK008792 AK018349 AK030366 AK030442 AK032975 AK019198 BC004707 AY548740 AY550262 JH002588 AAT40865.1 AAT42188.1 EGW11777.1 AGBW02007651 OWR54955.1 KQ459700 KPJ20335.1 CVRI01000065 CRL05799.1 ODYU01000635 SOQ35748.1 AHAT01031041 AHAT01031042 KB016878 EPY82951.1 CR450718 BC045443 BC075782 BC165019 AAH45443.1 AAH75782.1 AAI65019.1 AL953901 BK007695 DAA34563.1 AACZ04012940 ABGA01242736 ABGA01242737 ABGA01242738 ABGA01242739 NDHI03003457 PNJ45073.1 PNJ45074.1 PNJ45075.1 PNJ45076.1 GL441721 EFN64371.1 AY962101 AAX94036.1 LZPO01030506 OBS77350.1 AAQR03076677 AAQR03076678 AAQR03076679 AAQR03076680 AAQR03076681 AMGL01080243 AMGL01080244 GQ221053 ACV04833.1 GABZ01002661 JAA50864.1 AGCU01131594 AGCU01131595 AGCU01131596 AGCU01131597 AJVK01032485 JH170425 EHB09049.1 GFFW01003797 JAV40991.1 KN124398 KFO21292.1 AGTP01037516 AGTP01037517 AGTP01037518 AQIA01011083 CABD030083745 CABD030083746 ADFV01002626 ADFV01002627 ADFV01002628 ADFV01002629 JH881897 ELR51787.1 AQIB01022967 AQIB01022968 AQIB01022969 AQIB01022970 AJFE02022267 AJFE02022268 AJFE02022269 AHZZ02002230 AHZZ02002231 KB367542 ELV10488.1 MKHE01000003 OWK16923.1 AEMK02000028 DQIR01153398 GACC01000491 HDB08875.1 JAA74093.1 JL616029 AEH58236.1 GABC01009742 GABC01009741 GABC01009740 GABC01009739 GABC01009738 GABF01007676 GABD01008954 GABD01008951 GABE01007265 GABE01007264 GABE01007263 NBAG03000092 JAA01600.1 JAA14469.1 JAA24146.1 JAA37474.1 PNI89882.1 PNI89883.1 PNI89884.1 PNI89885.1 JSUE03006878 JSUE03006879 JU319960 JU319961 JU332138 JU332139 JU474940 JV043983 CM001263 AFE63716.1 AFH31744.1 AFI34054.1 EHH20800.1 GAMT01010071 GAMS01007853 GAMS01007852 GAMS01007851 GAMR01000100 GAMR01000092 GAMQ01006380 GAMP01001777 GAMP01001776 JAB01790.1 JAB15283.1 JAB33832.1 JAB35471.1 JAB50978.1 EU794599 CH471054 ACJ13653.1 EAW96760.1 S62077 L07515 AK313506 BC006821 U26311 AAKN02014963 AEFK01204204 CR760924 CAJ82321.1 AK402702 BAM19324.1 HAEA01003265 SBQ31745.1 AAMC01075965 BC074418 AAH74418.1 AFYH01066990 AFYH01066991 HADZ01017552 SBP81493.1 HAED01011315 HAEE01015363 SBQ97613.1 HADY01023007 HAEJ01001635 SBP61492.1 ACTA01139502 GL193035 EFB17765.1 HAEB01013091 SBQ59618.1 GFPF01006769 MAA17915.1 GEDV01011625 JAP76932.1 AAEX03014967 AEYP01084409 AANG04001751
Proteomes
UP000005204
UP000218220
UP000053268
UP000053240
UP000007151
UP000235965
+ More
UP000008672 UP000002494 UP000000589 UP000001075 UP000189706 UP000183832 UP000233020 UP000252040 UP000245320 UP000265300 UP000261681 UP000248483 UP000018468 UP000000437 UP000002277 UP000001595 UP000000311 UP000001646 UP000092124 UP000005225 UP000002356 UP000007267 UP000092462 UP000006813 UP000028990 UP000005215 UP000233120 UP000233100 UP000001519 UP000001073 UP000029965 UP000240080 UP000028761 UP000233200 UP000233060 UP000009136 UP000011518 UP000233160 UP000008227 UP000233040 UP000002281 UP000233220 UP000006718 UP000008225 UP000189704 UP000005640 UP000005447 UP000007648 UP000245300 UP000008143 UP000265140 UP000002279 UP000008912 UP000248482 UP000002254 UP000248481 UP000000715 UP000245340 UP000245341 UP000011712 UP000261680 UP000291021
UP000008672 UP000002494 UP000000589 UP000001075 UP000189706 UP000183832 UP000233020 UP000252040 UP000245320 UP000265300 UP000261681 UP000248483 UP000018468 UP000000437 UP000002277 UP000001595 UP000000311 UP000001646 UP000092124 UP000005225 UP000002356 UP000007267 UP000092462 UP000006813 UP000028990 UP000005215 UP000233120 UP000233100 UP000001519 UP000001073 UP000029965 UP000240080 UP000028761 UP000233200 UP000233060 UP000009136 UP000011518 UP000233160 UP000008227 UP000233040 UP000002281 UP000233220 UP000006718 UP000008225 UP000189704 UP000005640 UP000005447 UP000007648 UP000245300 UP000008143 UP000265140 UP000002279 UP000008912 UP000248482 UP000002254 UP000248481 UP000000715 UP000245340 UP000245341 UP000011712 UP000261680 UP000291021
Interpro
SUPFAM
SSF54160
SSF54160
CDD
ProteinModelPortal
H9J9B7
Q1HPP1
A0A2W1BHW0
R4IT63
A0A2A4J9V2
A0A1E1W5D8
+ More
A0A2H1X0H0 I4DNU2 A0A194R6F7 A0A212EWJ8 S4PWP7 A0A2J7RIV1 A0A194Q684 H3ARE6 B2RYU7 Q61686 Q6E6J6 A0A1U8BT65 A0A212FMI2 A0A194RSL3 A0A1J1J077 A0A2K5CRQ0 A0A2Y9FKU5 A0A341ARS8 A0A2U4CBG8 A0A340Y2E2 A0A383ZXC3 A0A2Y9N3J9 A0A2H1V4I1 A0A1U8BGU0 W5N7D5 S9Y6D8 Q7ZVR4 F1QM86 F0J9Z4 H2Q639 A0A2J8UIM0 E2AQB3 Q52T68 G1KFI8 A0A1A6HHC0 H0X953 C8BKD4 K9J4Y6 K7FA46 A0A1B0DE28 G5BID8 A0A250YBI4 A0A091CSL1 I3MNC5 A0A2K6ECP8 A0A2K5WBV7 G3QCU2 G1S7F7 L8I9B4 A0A0D9QZG1 A0A2R9A4K7 A0A2I3LLL9 A0A2K6QYW9 A0A2K5MPW2 F2Z4J7 L8Y296 A0A212DF96 A0A2K6G9A8 F2Z5T3 A0A2K5QBE6 F6UM66 A0A2K6THI9 K7AP88 F7C841 F7IG39 A0A1U7TLR6 V9HWG0 P45973 A0A286XDM7 G3W7D7 S4RV78 Q28HD9 I4DN34 A0A1A8DBS8 F6QIP4 A0A3P8XU08 F6T174 Q6GLP2 H3B1R7 A0A1A8CR17 A0A1A8IK97 A0A1A8B216 D2HM50 A0A1A8FL99 A0A224YLU2 A0A131YEL4 A0A2Y9L165 E2QYK6 A0A2Y9GXB4 M3Y376 A0A2U3WCN4 A0A2U3XBA2 A0A2I2U2I6 A0A384D763
A0A2H1X0H0 I4DNU2 A0A194R6F7 A0A212EWJ8 S4PWP7 A0A2J7RIV1 A0A194Q684 H3ARE6 B2RYU7 Q61686 Q6E6J6 A0A1U8BT65 A0A212FMI2 A0A194RSL3 A0A1J1J077 A0A2K5CRQ0 A0A2Y9FKU5 A0A341ARS8 A0A2U4CBG8 A0A340Y2E2 A0A383ZXC3 A0A2Y9N3J9 A0A2H1V4I1 A0A1U8BGU0 W5N7D5 S9Y6D8 Q7ZVR4 F1QM86 F0J9Z4 H2Q639 A0A2J8UIM0 E2AQB3 Q52T68 G1KFI8 A0A1A6HHC0 H0X953 C8BKD4 K9J4Y6 K7FA46 A0A1B0DE28 G5BID8 A0A250YBI4 A0A091CSL1 I3MNC5 A0A2K6ECP8 A0A2K5WBV7 G3QCU2 G1S7F7 L8I9B4 A0A0D9QZG1 A0A2R9A4K7 A0A2I3LLL9 A0A2K6QYW9 A0A2K5MPW2 F2Z4J7 L8Y296 A0A212DF96 A0A2K6G9A8 F2Z5T3 A0A2K5QBE6 F6UM66 A0A2K6THI9 K7AP88 F7C841 F7IG39 A0A1U7TLR6 V9HWG0 P45973 A0A286XDM7 G3W7D7 S4RV78 Q28HD9 I4DN34 A0A1A8DBS8 F6QIP4 A0A3P8XU08 F6T174 Q6GLP2 H3B1R7 A0A1A8CR17 A0A1A8IK97 A0A1A8B216 D2HM50 A0A1A8FL99 A0A224YLU2 A0A131YEL4 A0A2Y9L165 E2QYK6 A0A2Y9GXB4 M3Y376 A0A2U3WCN4 A0A2U3XBA2 A0A2I2U2I6 A0A384D763
PDB
5T1G
E-value=1.5005e-20,
Score=241
Ontologies
GO
GO:0005634
GO:0005719
GO:0045892
GO:0005721
GO:0042803
GO:0090734
GO:0000118
GO:0017053
GO:0000784
GO:1990904
GO:0035064
GO:0000122
GO:0000776
GO:0006974
GO:0003682
GO:0042826
GO:0030674
GO:0043021
GO:0010369
GO:0016605
GO:0035097
GO:0070491
GO:0005720
GO:0005730
GO:0044877
GO:0042802
GO:0000792
GO:0032991
GO:0005654
GO:1990226
GO:0001939
GO:0005819
GO:0001940
GO:0016740
GO:0016032
GO:0031618
GO:0005635
GO:0007596
GO:0070317
GO:0003677
GO:0003700
GO:0006355
GO:0006508
GO:0006811
GO:0016020
GO:0005515
GO:0003779
GO:0016021
PANTHER
Topology
Subcellular location
Nucleus
Chromosome Colocalizes with HNRNPU in the nucleus (By similarity). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. With evidence from 4 publications.
Centromere Colocalizes with HNRNPU in the nucleus (By similarity). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. With evidence from 4 publications.
Chromosome Colocalizes with HNRNPU in the nucleus (By similarity). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. With evidence from 4 publications.
Centromere Colocalizes with HNRNPU in the nucleus (By similarity). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. With evidence from 4 publications.
Length:
191
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00036
Exp number, first 60 AAs:
0
Total prob of N-in:
0.42394
outside
1 - 191
Population Genetic Test Statistics
Pi
41.042126
Theta
193.586011
Tajima's D
-2.133534
CLR
67.43453
CSRT
0.00764961751912404
Interpretation
Uncertain
