SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01641
Pre Gene Modal
BGIBMGA006099
Annotation
Na?K-ATPase_beta-subunit_[Bombyx_mori]
Full name
Sodium/potassium-transporting ATPase subunit beta-2      
Alternative Name
Protein nervana 2
Sodium/potassium-dependent ATPase subunit beta-2
Location in the cell
Nuclear   Reliability : 2.842
 

Sequence

CDS
ATGACGGTTAAGAAACGAACATCCGACCTGACGAGCTTAGAGCGATTCAACATGTACTACAGGGAGAAGGAACCACCTCTAACCAGATCTCAAAAAGTGAAACGGTTCATCTGGAACCCGAAGACCAGGCAGTTCTGTGGAAGAACAGGATCTAGTTGGTCAAAAATAGCATTGTTCTATTTTATCTTCTACTCCGCACTCGCCATCCTAGTCGCTATCTGCATGTGGACGTTCCTCCAGCTTTTGGATGCTAGGCAACCGAAATGGCAGCTCGAGAGGAGCATCATTGGCACTAACCCAGGGCTGGGCTTCAGGCCAACGCCTCCGGAGGTCGCCAGCAGTGTCATCTGGTACAAGGGAAATGACCCGGGTAGCCAACAGTTCTGGGTTAAAAAGCTATCCACCTTCTTAGCTGCGTACAAGCGCGATGGCAAAAAAGCTGGTGCGGGCCAGAACATCCACAACTGTGACTTCAAGCTTCCTCCTCCGGCTGGGAAAGTCTGCGATGTAGACATCAGCGCGTGGGGACCTTGCGTGCAGGACAACTATTTCGGCTACCACAAATCGACACCCTGCATCTTCCTGAAGCTAAATAAGATCTACGGTTGGAGGCCCAAGTTCTACAACAGCTCTGACAATCTACCCAAAGACATGCCGGAAGACTTGAAGGAGCACATCAGGAACATGACGGCGTATGATAAGAACTACCTAAACATGGTTTGGGTTTCCTGCCAAGGCGAGAACCCAGCTGATCGCGAGAACATTGGTCCCATACAGTACCTACCTCACCGAGGCTTCCCGGGATACTACTTCCCCTACACCAACCAAGAAGGATACCTGAGCCCTCTTGTAGCTGTGCACTTGCAGAGACCTAAGACTGGCATGTTAATCAACATTGAATGTCGTGCCTGGGCGAACAACATCAAGTATGAGAGACTTGAAGCCATGGGCTCTGTACACATCGAGATGTTGATCGAGTAG
Protein
MTVKKRTSDLTSLERFNMYYREKEPPLTRSQKVKRFIWNPKTRQFCGRTGSSWSKIALFYFIFYSALAILVAICMWTFLQLLDARQPKWQLERSIIGTNPGLGFRPTPPEVASSVIWYKGNDPGSQQFWVKKLSTFLAAYKRDGKKAGAGQNIHNCDFKLPPPAGKVCDVDISAWGPCVQDNYFGYHKSTPCIFLKLNKIYGWRPKFYNSSDNLPKDMPEDLKEHIRNMTAYDKNYLNMVWVSCQGENPADRENIGPIQYLPHRGFPGYYFPYTNQEGYLSPLVAVHLQRPKTGMLINIECRAWANNIKYERLEAMGSVHIEMLIE

Summary

Description
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Subunit
The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.
Similarity
Belongs to the X(+)/potassium ATPases subunit beta family.
Keywords
Alternative splicing   Cell membrane   Complete proteome   Disulfide bond   Glycoprotein   Ion transport   Membrane   Potassium   Potassium transport   Reference proteome   Signal-anchor   Sodium   Sodium transport   Transmembrane   Transmembrane helix   Transport  
Feature
chain  Sodium/potassium-transporting ATPase subunit beta-2
splice variant  In isoform 2.1.
EMBL
LC029031    BAS22118.1    KQ459584    KPI98479.1    KZ150105    PZC73422.1    + More
NWSH01000323    PCG77484.1    ODYU01004281    SOQ43980.1    AGBW02010580    OWR48239.1    KQ460644    KPJ13274.1    BABH01004376    BABH01004377    QOIP01000009    RLU18375.1    KQ981701    KYN37501.1    GL767674    EFZ13198.1    KQ982612    KYQ53877.1    KQ976453    KYM85348.1    ADTU01008623    GL453340    EFN76208.1    GL888206    EGI65177.1    GL439967    EFN66488.1    KK107119    EZA58729.1    KQ977513    KYN02161.1    KQ978949    KYN27360.1    UFQT01000377    SSX23727.1    KPI98482.1    ODYU01000439    SOQ35210.1    JR049281    AEY60917.1    KQ766043    OAD53764.1    GAKP01015263    GAKP01015262    JAC43690.1    KQ434782    KZC04576.1    GAMC01019727    JAB86828.1    GBXI01005074    GBXI01003386    JAD09218.1    JAD10906.1    AAAB01008964    EAA12801.3    KQ414813    KOC60536.1    CH940649    EDW63592.1    CH477641    EAT37924.1    EAT37926.1    GALA01001003    JAA93849.1    GFDF01008939    JAV05145.1    GFDL01000429    JAV34616.1    CH916368    EDW02899.1    JRES01001704    KNC20746.1    CH933807    EDW11716.1    KA649142    AFP63771.1    NNAY01002286    OXU21622.1    PZC73425.1    GDHF01030989    GDHF01028963    GDHF01005372    JAI21325.1    JAI23351.1    JAI46942.1    CH963920    EDW78067.1    GAKP01015261    GAKP01015260    GAKP01015259    JAC43692.1    DS235744    EEB16200.1    KF813100    AHH35013.1    AXCN02002071    AXCN02002072    KRF81175.1    NWSH01001558    PCG70862.1    GANO01002628    JAB57243.1    OWR48236.1    SSX23728.1    CM000157    EDW87836.1    KRJ97426.1    KRJ97427.1    GBXI01006452    GBXI01004712    GBXI01002506    JAD07840.1    JAD09580.1    JAD11786.1    AE014134    AAX52659.1    AGB92700.1    U22439    U22440    AY060289    EJY57851.1    GAMC01019728    JAB86827.1    KRF98806.1    CM002910    KMY88625.1    CH480818    EDW51910.1    GAPW01002579    JAC11019.1    CH954177    EDV59132.1    CH902620    EDV31580.1    KPU73493.1    KPU73494.1    GGFL01003105    MBW67283.1    CCAG010002985    CCAG010002986    GGFM01001775    MBW22526.1    KRG02858.1    GGFL01003076    MBW67254.1    GFDF01009089    JAV04995.1    GAMD01000463    JAB01128.1    GGFK01006218    MBW39539.1    JXUM01034452    JXUM01034453    JXUM01034454    JXUM01034455    JXUM01034456    KQ561023    KXJ79990.1    BT025048    AAF52439.1    AAX52660.1    ABE73219.1    KMY88624.1    KMY88626.1    KMY88627.1    KMY88628.1    CH379058    EAL34483.1    CH479184    EDW36934.1    KRJ97425.1    KK852595    KDR20644.1    GGFJ01007372    MBW56513.1    GFDL01007628    JAV27417.1    KQS70647.1    KPU73492.1    OUUW01000010    SPP85694.1   
Pfam
PF00287   Na_K-ATPase
Interpro
IPR000402   Na/K_ATPase_sub_beta        + More
IPR038702   Na/K_ATPase_sub_beta_sf       
Gene 3D
PDB
4XE5     E-value=6.77949e-29,     Score=316

Ontologies

Topology

Subcellular location
Cell membrane  
Length:
326
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
22.88913
Exp number, first 60 AAs:
4.03857
Total prob of N-in:
0.99121
inside
1  -  56
TMhelix
57  -  79
outside
80  -  326
 
 

Population Genetic Test Statistics

Pi
201.236599
Theta
163.043747
Tajima's D
0.706672
CLR
0
CSRT
0.576421178941053
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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