Gene

KWMTBOMO01617

Pre Gene Modal

BGIBMGA006075

Annotation

PREDICTED:_kidney_mitochondrial_carrier_protein_1_[Plutella_xylostella]

Location

Bomo_Chr4(-):434082-439171      View in EpiBrowser

Full name

Mitochondrial uncoupling protein Bmcp      

Alternative Name

Brain mitochondrial carrier protein 1
Mitochondrial uncoupling protein 5

Location in the cell

PlasmaMembrane   Reliability : 4.233

CDS

ATGGGAGAACGTAATTGGCGACCGTTTATTTACGGTGGATTAGCGTCCATAGTTGCAGAATTCGGCACATTCCCTATCGATACAACCAAAACTCGTCTTCAAATCCAAGGACAGAAGATAGATCCTCGTCATGTTGAACTACGGTATACTGGGATGGTGGACTGCATCATCAAAACTTCCAAGCAAGAGGGTGTCAAGGCTTTATATTGTGGCATTTGGCCGGCGGTGCTGCGACAAGCGACGTATGGCACGATTAAGTTTGGTACCTACTATACGCTGAAGAACGCGCTCGCCAAGAGACGAGCGGACGGTGGAACGAAGGAGCACCTCCCTACGAACACTTTCTGTGCTGCCTTTGCGGGTGGACTGTCCAGTGCTATTGCCAACCCTACCGACGTACTAAAAGTGCGGATGCAGATGGGCGAGGAGAAGCGCAACCTGGTGCGTTGCTTCCTGGACATATACCGCACGGAGGGTCGCGGCGGGCTGTGGCGCGGCGTGGGGCCCACGTCGCAGCGCGCCGCCGTCATCGCGGCCGTGGAGCTGCCCGTGTACGACGCCGCCAAGCGCCGCCTGCTGGGCCCGCTCGGAGACTCGCCGCCCAACCACCTGCTGTCCAGCCTGCTCGCCTCGCTGGGCAGCGCCGTGGCCAGCACGCCGCTAGACGTCTTGCGGACGCGGCTAATGAACCAAAGAAAAATTTTAGATCACCAAATAAGGACAAACGAAATAATTTACAAAGGAACCGTCGACTGTCTCCTGCAGACGGTGCGCAGCGAGGGTGCGCGCGCGCTGTACAAGGGGTTCGTGCCGACGTGGCTGCGGATGGGGCCCTGGAACATCATATTCTTCATTACCTACGAGCAGCTCAAGCAGCTCTACTAG

Protein

MGERNWRPFIYGGLASIVAEFGTFPIDTTKTRLQIQGQKIDPRHVELRYTGMVDCIIKTSKQEGVKALYCGIWPAVLRQATYGTIKFGTYYTLKNALAKRRADGGTKEHLPTNTFCAAFAGGLSSAIANPTDVLKVRMQMGEEKRNLVRCFLDIYRTEGRGGLWRGVGPTSQRAAVIAAVELPVYDAAKRRLLGPLGDSPPNHLLSSLLASLGSAVASTPLDVLRTRLMNQRKILDHQIRTNEIIYKGTVDCLLQTVRSEGARALYKGFVPTWLRMGPWNIIFFITYEQLKQLY

Description

Regulates metabolic homeostasis in response to nutritional cues and may therefore be involved in adaptation to dietary variations. May not function in creating mitochondrial proton leaks across the inner mitochondrial membrane (i.e. mitochondrial uncoupling).

Similarity

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Complete proteome   Membrane   Mitochondrion   Mitochondrion inner membrane   Reference proteome   Repeat   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Mitochondrial uncoupling protein Bmcp

Uniprot

H9J983   A0A2H1WNQ6   A0A2A4K8W0   A0A194PYP1   A0A2W1BQ82   A0A194RBM3   + More
A0A212F7Z8   T1HPD8   A0A084WIT3   A0A023F4F1   A0A182N3X4   A0A1B6BW30   A0A182P501   A0A182Q8H5   A0A182KAJ9   A0A182W1Y7   A0A067QSF8   A0A182JF76   A0A182HHF1   A0A182XGT4   Q7PZC5   A0A182L4Y6   A0A182R8T5   A0A182VMN4   A0A182M2T9   A0A1Y1NAT7   A0A182FUZ1   A0A2M4BUB0   A0A2M4AM23   A0A2M3Z6N6   W5JWQ0   A0A182U642   A0A182Y9B9   A0A0K8TSW0   E2BDN4   A0A151JP35   A0A195CTK1   F4WBE5   K7IRK8   A0A151X9Q0   J3JY50   A0A232FHY7   A0A026W7T6   A0A3L8DAK1   A0A154P5N5   A0A1B6LQ15   A0A310SL14   W8BRQ8   A0A0L7R760   W8BLB1   A0A1B6G019   A0A336LJS6   A0A0K8UPQ1   A0A034WCH9   A0A0A1WEX5   A0A088A051   A0A1B6ICW2   A0A151HYL4   A0A1B0ET06   D6WMA1   A0A158NAY2   A0A0M3QX12   E9GDL6   A0A0P5HHE7   B4IZB5   A0A1I8PJH7   B4LCR7   B4N4L2   A0A0L0BVB8   A0A1I8NE32   U4UA65   A0A1W4W867   A0A1Y1N499   B4KUT2   B4HEY0   B4QQA4   A0A1B0B1A7   B4PFN4   B3M4B7   Q7K566   A0A3B0J563   B3NGZ8   Q29DX3   A0A1L8E155   A0A1B0A2J5   D3TPT4   A0A0N8CZF5   A0A087UAH3   A0A1B0GPH9   A0A1B0B1A5   A0A1B0FDB0   A0A1B0A2J4   T1IYK8   A0A1A9YEL2   A0A1S3HDE7   A0A1A9X0C5   A0A2L2Y4H2   H3A8J3   H9H7G9   A0A0B6Y7I0  

Pubmed

19121390    26354079    28756777    22118469    24438588    25474469    + More
24845553    12364791    14747013    17210077    20966253    28004739    20920257    23761445    25244985    26369729    20798317    21719571    20075255    22516182    23537049    28648823    24508170    30249741    24495485    25348373    25830018    18362917    19820115    21347285    21292972    17994087    26108605    25315136    22936249    17550304    10731132    12537572    12537569    15337852    16387864    18057021    15632085    20353571    26383154    26561354    9215903    17495919   

EMBL

BABH01004342    ODYU01009945    SOQ54699.1    NWSH01000047    PCG80233.1    KQ459584    + More
KPI98452.1    KZ149934    PZC77222.1    KQ460644    KPJ13301.1    AGBW02009824    OWR49839.1    ACPB03001473    ATLV01023946    KE525347    KFB50127.1    GBBI01002665    JAC16047.1    GEDC01031796    JAS05502.1    AXCN02001095    KK853078    KDR11711.1    APCN01002408    AAAB01008986    EAA00326.4    AXCM01004284    GEZM01013131    JAV92727.1    GGFJ01007516    MBW56657.1    GGFK01008509    MBW41830.1    GGFM01003414    MBW24165.1    ADMH02000001    ETN68143.1    GDAI01000156    JAI17447.1    GL447678    EFN86196.1    KQ978820    KYN28123.1    KQ977279    KYN04000.1    GL888062    EGI68501.1    KQ982365    KYQ57116.1    APGK01032728    BT128174    KB740848    AEE63135.1    ENN78700.1    NNAY01000176    OXU30292.1    KK107348    EZA52152.1    QOIP01000010    RLU17364.1    KQ434809    KZC06440.1    GEBQ01014230    GEBQ01011019    GEBQ01006813    JAT25747.1    JAT28958.1    JAT33164.1    KQ764717    OAD54427.1    GAMC01006992    JAB99563.1    KQ414643    KOC66674.1    GAMC01006993    JAB99562.1    GECZ01014003    JAS55766.1    UFQT01000028    UFQT01000132    SSX18186.1    SSX20628.1    GDHF01023753    GDHF01000188    JAI28561.1    JAI52126.1    GAKP01007454    JAC51498.1    GBXI01017061    JAC97230.1    GECU01022922    JAS84784.1    KQ976739    KYM75616.1    AJWK01005350    KQ971343    EFA03336.1    ADTU01010482    CP012525    ALC45059.1    GL732540    EFX82458.1    GDIQ01227917    JAK23808.1    CH916366    EDV96670.1    CH940647    EDW70959.1    CH964095    EDW79086.1    JRES01001286    KNC23928.1    KB631868    ERL86825.1    GEZM01013129    JAV92731.1    CH933809    EDW19338.1    CH480815    EDW41149.1    CM000363    CM002912    EDX10122.1    KMY99058.1    JXJN01007042    CM000159    EDW94183.1    CH902618    EDV39387.1    AE014296    AY051433    AAK92857.1    OUUW01000002    SPP76765.1    CH954178    EDV51455.1    KQS43813.1    CH379070    EAL30290.1    GFDF01001859    JAV12225.1    CCAG010006850    EZ423436    ADD19712.1    GDIP01083807    JAM19908.1    KK119005    KFM74362.1    AJVK01059705    AFFK01020311    IAAA01006706    LAA02200.1    AFYH01204786    AFYH01204787    AFYH01204788    AFYH01204789    AFYH01204790    HACG01005442    CEK52307.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000015103    + More
UP000030765    UP000075884    UP000075885    UP000075886    UP000075881    UP000075920    UP000027135    UP000075880    UP000075840    UP000076407    UP000007062    UP000075882    UP000075900    UP000075903    UP000075883    UP000069272    UP000000673    UP000075902    UP000076408    UP000008237    UP000078492    UP000078542    UP000007755    UP000002358    UP000075809    UP000019118    UP000215335    UP000053097    UP000279307    UP000076502    UP000053825    UP000005203    UP000078540    UP000092461    UP000007266    UP000005205    UP000092553    UP000000305    UP000001070    UP000095300    UP000008792    UP000007798    UP000037069    UP000095301    UP000030742    UP000192221    UP000009192    UP000001292    UP000000304    UP000092460    UP000002282    UP000007801    UP000000803    UP000268350    UP000008711    UP000001819    UP000092445    UP000092444    UP000054359    UP000092462    UP000092443    UP000085678    UP000091820    UP000008672    UP000002280   

PRIDE

H9J983    Q7K566   

Pfam

PF00153   Mito_carr        + More
PF03348   Serinc

Interpro

IPR023395   Mt_carrier_dom_sf        + More
IPR002067   Mit_carrier       
IPR018108   Mitochondrial_sb/sol_carrier       
IPR002113   Aden_trnslctor       
IPR032933   SLC25A14       
IPR002030   Mit_uncoupling_UCP-like       
IPR029554   SERINC2       
IPR005016   TDE1/TMS       

SUPFAM

SSF103506   SSF103506       

Gene 3D

1.50.40.10    

ProteinModelPortal

H9J983   A0A2H1WNQ6   A0A2A4K8W0   A0A194PYP1   A0A2W1BQ82   A0A194RBM3   + More
A0A212F7Z8   T1HPD8   A0A084WIT3   A0A023F4F1   A0A182N3X4   A0A1B6BW30   A0A182P501   A0A182Q8H5   A0A182KAJ9   A0A182W1Y7   A0A067QSF8   A0A182JF76   A0A182HHF1   A0A182XGT4   Q7PZC5   A0A182L4Y6   A0A182R8T5   A0A182VMN4   A0A182M2T9   A0A1Y1NAT7   A0A182FUZ1   A0A2M4BUB0   A0A2M4AM23   A0A2M3Z6N6   W5JWQ0   A0A182U642   A0A182Y9B9   A0A0K8TSW0   E2BDN4   A0A151JP35   A0A195CTK1   F4WBE5   K7IRK8   A0A151X9Q0   J3JY50   A0A232FHY7   A0A026W7T6   A0A3L8DAK1   A0A154P5N5   A0A1B6LQ15   A0A310SL14   W8BRQ8   A0A0L7R760   W8BLB1   A0A1B6G019   A0A336LJS6   A0A0K8UPQ1   A0A034WCH9   A0A0A1WEX5   A0A088A051   A0A1B6ICW2   A0A151HYL4   A0A1B0ET06   D6WMA1   A0A158NAY2   A0A0M3QX12   E9GDL6   A0A0P5HHE7   B4IZB5   A0A1I8PJH7   B4LCR7   B4N4L2   A0A0L0BVB8   A0A1I8NE32   U4UA65   A0A1W4W867   A0A1Y1N499   B4KUT2   B4HEY0   B4QQA4   A0A1B0B1A7   B4PFN4   B3M4B7   Q7K566   A0A3B0J563   B3NGZ8   Q29DX3   A0A1L8E155   A0A1B0A2J5   D3TPT4   A0A0N8CZF5   A0A087UAH3   A0A1B0GPH9   A0A1B0B1A5   A0A1B0FDB0   A0A1B0A2J4   T1IYK8   A0A1A9YEL2   A0A1S3HDE7   A0A1A9X0C5   A0A2L2Y4H2   H3A8J3   H9H7G9   A0A0B6Y7I0  

PDB

2LCK     E-value=3.79385e-41,     Score=421

KEGG

101743508    K15106 solute carrier family 25 (mitochondrial carrier), member 14/30 | (RefSeq) kidney mitochondria

GO

GO:0022857   GO:0016021   GO:0005743   GO:0006839   GO:0031966   GO:0015116   GO:0035435   GO:0015117   GO:0015709   GO:0071423   GO:0015297   GO:0015141   GO:0008272   GO:0015729   GO:0015140   GO:0071422   GO:0015131   GO:0019222   GO:0007605   GO:0055085  

PANTHER

PTHR45618:SF20   PTHR10383:SF22   PTHR10383  

Subcellular location

Mitochondrion inner membrane  

Length:

294

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.94886

Exp number, first 60 AAs:

2.02401

Total prob of N-in:

0.13808

outside

1  -  294

 

 

Pi

230.139694

Theta

174.216758

Tajima's D

1.3914

CLR

0

CSRT

0.76151192440378

Interpretation

Uncertain