Gene

KWMTBOMO01590

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr3(-):14695290-14699038      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.795

CDS

ATGATACTCGTGGCGTTAGAACCCACCCCGGAGGCCAAAAAGAAGATCGCATGTCTCACGACAATTTGCGGCCTATCCGGGATCTCAATCGAAGCCCCCCACAAGCGTGGCACTCCCGGGCAGTGCTACAGATGTCAGCTTTACGGCCACTCGGCTCGCAATTGCCACGCGCGCCCCCGCTGCGTAAAGTGCCTCGGCGACCACGCCACACTAGATTGCTCGCGTGTTAGGGAAACCGCGACCGAACCCCCAAGCTGTGTCCTATGCCTTAAGCAAGGGCACCCCGCGAACTACCGTGGATGTCCTAGGGCTCCGCGCAAGCGTTCAACCCTCCCAGCTCCGCGAACCGTCGGCCCAAAGACTTCGGCACCCTCAGTGCCGAAACCTGCCTTCGTGCCGGCTGCAGTTCCCACGGTTTCAGCGTGGAAAAAGCCGCTGCCGTATACGAAGGCGGGAACACAAACCGCACCCCCGCCCCCGCTCGCGACACGCCCCGCGCCTCAGCCCCTGCTCGCACCTCGCCCCGCGCCCGCGTTCCGTCCCCCGCAACCCTCTGCCGCCAACGACTTCGCGCTCGTGCGCGACTTCGTCACCGCGGTGAACTTCGACCGTCTGCGATCGTTCGCTGACGCTATCCGTAGGTCGACAACCCCCGAACAGCGGCTCGCGGCCGCGTTCGATCACATGGACGTTTACGAGTCCGTGTCGCCATTCTATAATGCTAACGGACTCGCGCGGCAACGCGATCAAATTTTTGAATTCCTCCGCGATAATCTTGTAGATATTCTATTAGTGCAGGAAACCTGTCTGAAGCCCTCGCGTCGCGACCCGAAAGTCGCGAACTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACTCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACAAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACCTTTGAAATAGTCGGCCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCTCACAACCCAGTCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGACGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCCATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCTAAAGAAGTCGATATGGAGGACAGCTTCCACCGCATCAGACTGTCCCCCGATCTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCAGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCTTAAGCGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCTTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACGGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGCACCAGGCTCCGACGGCATCCACAACCGCGCGCTAAAATTTTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTCCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGAGAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCTCGACGATAGGAAAAATTTACGAACGTCTCCTTAGAAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCAAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATTCTGATAGGGCTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATTAACCCCACGAAAAGCGCAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACCTCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATTCCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACTCTCGACAGAGGGATGACATTCCGTCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGCAAACTGTCCCTCCGCAATAAGGTAACTCTCTACAAAACTTGCATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCGCACCCACTTGAAATCCCTTCAGGTTATTCAATCACGATTCTGCAGGATAGCCGTCGGAGCGCCTTGGTTCCTTAGGAATGTGGATCTCCACGACGACCTGGAGCTCGACTCTCTTAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTTTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MILVALEPTPEAKKKIACLTTICGLSGISIEAPHKRGTPGQCYRCQLYGHSARNCHARPRCVKCLGDHATLDCSRVRETATEPPSCVLCLKQGHPANYRGCPRAPRKRSTLPAPRTVGPKTSAPSVPKPAFVPAAVPTVSAWKKPLPYTKAGTQTAPPPPLATRPAPQPLLAPRPAPAFRPPQPSAANDFALVRDFVTAVNFDRLRSFADAIRRSTTPEQRLAAAFDHMDVYESVSPFYNANGLARQRDQIFEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTVTRTMVDWNKLGTCLADAAPPILPYGPDSNPSPEDTVESINIITDHISSAIIRSSKEVDMEDSFHRIRLSPDLRNLLRVRNAAIRAYDRLPTHSNRIQMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLLRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIHNRALKFLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPRNETSSYRPISLLSTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTHLKSLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSLSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   Q07995   X1WLB2   A0A2S2Q383   A0A3N5Z7I3   A0A2J7QR37   A0A2M4CV42   J9LC21   A0A2J7QY69   A0A2M4CV52   A0A2J7PBY3   A0A2M4BD66   X1WNI2   A0A2M4BDA5   A0A2J7PU96   A0A2M4BD62   A0A087UGF5   A0A224X6Q4   J9LFC9   A0A2M4BD67   A0A2S2QEE0   A0A2M4BDV6   A0A2J7Q6J2   A0A2J7R7D0   X1WZH0   V9GZF1   X1WQI9   A0A224XB44   A0A2S2NGV8   A0A224X6T4   A0A2S2N814   A0A224X6S1   A0A069DZL8   A0A224X746   K7IN67   A0A224X6U5   A0A2H8TF37   A0A224XI99   Q8I7P8   A0A1Y1KFR3   A0A224X6R6   P21328   A0A2J7PDM0   A0A2S2R9D4   A0A0A9YJ00   A0A0A9YU04   A0A2M4CVF1   A0A2J7QB68   A0A2M4CVK2   A0A069DX78   P21329   A0A2S2P698   A0A2J7PVX3   A0A1B6EGD8   A0A0V0G5B6   A0A2A4IUM2   A0A224XHW8   A0A224XJI0   Q95SX7   A0A1W7R682   A0A2S2NPG3   Q8T9X4   A0A2S2PJG2   A0A224X6W2   J9KLB1   Q24335  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    1327974    26334808    20075255    2463954    3040362    1714378    25401762    1701254    7753626    12537569    2441397   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GBBI01004571    JAC14141.1    S59870    AAB26437.2    ABLF02042518    ABLF02057746    GGMS01002992    MBY72195.1    RPOV01000134    RPJ78669.1    NEVH01011985    PNF31054.1    GGFL01005012    MBW69190.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    NEVH01009134    PNF33528.1    GGFL01004957    MBW69135.1    NEVH01027074    PNF13841.1    GGFJ01001844    MBW50985.1    ABLF02008153    ABLF02008462    ABLF02008464    GGFJ01001842    MBW50983.1    NEVH01021205    PNF19912.1    GGFJ01001843    MBW50984.1    KK119692    KFM76444.1    GFTR01008279    JAW08147.1    ABLF02023911    GGFJ01001858    MBW50999.1    GGMS01006359    MBY75562.1    GGFJ01001857    MBW50998.1    NEVH01017470    PNF24199.1    NEVH01006736    PNF36716.1    ABLF02034467    M95171    AAA29354.1    ABLF02022418    GFTR01008262    JAW08164.1    GGMR01003407    MBY16026.1    GFTR01008261    JAW08165.1    GGMR01000676    MBY13295.1    GFTR01008271    JAW08155.1    GBGD01000415    JAC88474.1    GFTR01008151    JAW08275.1    GFTR01008251    JAW08175.1    GFXV01000908    MBW12713.1    GFTR01008256    JAW08170.1    AY180919    AAN87272.1    GEZM01084969    JAV60363.1    GFTR01008269    JAW08157.1    M22874    M38643    NEVH01026386    PNF14434.1    GGMS01017365    MBY86568.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GGFL01005122    MBW69300.1    NEVH01016302    PNF25823.1    GGFL01005121    MBW69299.1    GBGD01000389    JAC88500.1    M38437    GGMR01012305    MBY24924.1    NEVH01020940    PNF20481.1    GEDC01000337    JAS36961.1    GECL01003538    JAP02586.1    NWSH01007753    PCG62823.1    GFTR01008254    JAW08172.1    GFTR01008257    JAW08169.1    AY060438    AAL25477.1    GEHC01000968    JAV46677.1    GGMR01006408    MBY19027.1    AF456125    AAL57609.1    GGMR01016905    MBY29524.1    GFTR01008260    JAW08166.1    ABLF02040174    ABLF02040183    ABLF02055266    M17214    AAA28508.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000218220   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q8I7P8    P21328    P21329    + More
Q95SX7    Q8T9X4    Q24335   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   Q07995   X1WLB2   A0A2S2Q383   A0A3N5Z7I3   A0A2J7QR37   A0A2M4CV42   J9LC21   A0A2J7QY69   A0A2M4CV52   A0A2J7PBY3   A0A2M4BD66   X1WNI2   A0A2M4BDA5   A0A2J7PU96   A0A2M4BD62   A0A087UGF5   A0A224X6Q4   J9LFC9   A0A2M4BD67   A0A2S2QEE0   A0A2M4BDV6   A0A2J7Q6J2   A0A2J7R7D0   X1WZH0   V9GZF1   X1WQI9   A0A224XB44   A0A2S2NGV8   A0A224X6T4   A0A2S2N814   A0A224X6S1   A0A069DZL8   A0A224X746   K7IN67   A0A224X6U5   A0A2H8TF37   A0A224XI99   Q8I7P8   A0A1Y1KFR3   A0A224X6R6   P21328   A0A2J7PDM0   A0A2S2R9D4   A0A0A9YJ00   A0A0A9YU04   A0A2M4CVF1   A0A2J7QB68   A0A2M4CVK2   A0A069DX78   P21329   A0A2S2P698   A0A2J7PVX3   A0A1B6EGD8   A0A0V0G5B6   A0A2A4IUM2   A0A224XHW8   A0A224XJI0   Q95SX7   A0A1W7R682   A0A2S2NPG3   Q8T9X4   A0A2S2PJG2   A0A224X6W2   J9KLB1   Q24335  

PDB

6AR3     E-value=0.00105999,     Score=105

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676   GO:0043666   GO:0004190   GO:0006508   GO:0006811   GO:0016020   GO:0005515   GO:0003779   GO:0016021  

Length:

1182

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.558049999999999

Exp number, first 60 AAs:

0.00368

Total prob of N-in:

0.00022

outside

1  -  1182

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

186.166408

CSRT

0

Interpretation

Uncertain