Gene

KWMTBOMO01573

Annotation

PREDICTED:_protein_aveugle_[Amyelois_transitella]

Location

Bomo_Chr3(-):14175174-14176539      View in EpiBrowser

Full name

Protein aveugle      

Location in the cell

Mitochondrial   Reliability : 1.333 Nuclear   Reliability : 1.884

CDS

ATGGTGGAAGAACCGAATCTTAATTCAAGTAAACCCAAAGCGAAAACGACCCGTCCCAAAGCTATATATTTATGGACAGAAGCCGACGTCCAAAAGTGGCTTCGACGCCACTGTAGTGATTATTATCATATGTACTGGGAGAGTTTTCACGAGCATGACATAACAGGTAGAGCTCTAGTCCGTATCAATGACAACACATTACTTCGAATGGGTATCAACAACAAAGATCACAGGGAAGCCATATGGAGGGAAATCTTAAAACTTAGACTGAAAGCTGACATAGTCGAGATCCGTGATTTAGAACGTAGGCATAACTATTTTAATTATGACTTGTGA

Protein

MVEEPNLNSSKPKAKTTRPKAIYLWTEADVQKWLRRHCSDYYHMYWESFHEHDITGRALVRINDNTLLRMGINNKDHREAIWREILKLRLKADIVEIRDLERRHNYFNYDL

Description

Required for normal photoreceptor differentiation between Ras and Raf for EGFR signaling in the eye and for mitogen-activated protein kinase phosphorylation. Probably acts together with Cnk to promote Raf activation, perhaps by recruiting an activating kinase.

Subunit

Interacts with the SAM domain of cnk.

Miscellaneous

'Aveugle' means 'blind' in French.

Keywords

3D-structure   Complete proteome   Cytoplasm   Membrane   Reference proteome   Sensory transduction   Vision  

Feature

chain  Protein aveugle

Uniprot

A0A2W1BQX2   A0A2H1W6H4   A0A2A4J2T1   A0A1E1WID3   S4PTB1   A0A0N0PAU7   + More
A0A194Q2G8   A0A2P8ZI11   A0A2J7RQR4   A0A067RD26   A0A0N7Z8Y7   R4G818   A0A0V0G7D0   A0A069DVI1   A0A1B6EFB1   A0A0M8ZVF2   U4UGC3   J3JVP6   A0A1W4WTV8   E2BTE0   R4WQ63   A0A154PEP3   D6WUY3   A0A310SR28   E2ARH1   A0A2A3E0G5   V9IE46   A0A088AK94   A0A0A9Z9B1   A0A1Y1LS78   A0A158NQB1   A0A026WQC8   A0A1B6HSZ2   A0A310SGQ1   A0A151K350   A0A1B6FQ93   K7IQ21   A0A232F8U4   A0A1B6MMI4   E9GS85   A0A195B547   A0A151WGI0   A0A0P5IYV3   A0A0P5PC63   A0A0P4XK11   A0A2R7W450   H9JN51   A0A0T6AX06   A0A0P5FD74   A0A2H8TQD2   A0A2S2PQD1   B4HRN8   A0A0P4WI92   J9JZT8   A0A2S2Q3U3   A0A3Q0JNX5   W8BMX1   A0A1B2AIY1   B3NQT3   B4QFY1   Q8ML92   B4P7N5   B4KNN3   Q16IB6   B4J6L1   A0A0M5JA71   A0A0L0CT42   A0A1W4UJC2   A0A0K8UN29   Q1HRF9   B4LM77   A0A1A9WHW5   Q291B9   B4GAY0   B3ME31   A0A3B0JW41   B4MNS4   A0A182GBC0   B0W577   A0A1Q3FHN9   A0A023EFV0   A0A0L7QQE1   A0A1A9V2M3   A0A1B0C5F3   E0VKS9   A0A084WUK4   A0A182IU65   A0A087TCD1   A0A336MVQ8   T1J8M7   A0A1V9X1Y4   A0A182LT37   A0A1I8Q9C0   A0A182PGD0   A0A1I8M9E0   A0A182YQ94   A0A182RAJ8   A0A182W284   T1DKT4  

Pubmed

28756777    23622113    26354079    29403074    24845553    27129103    + More
26334808    23537049    22516182    20798317    23691247    18362917    19820115    25401762    28004739    21347285    24508170    20075255    28648823    21292972    19121390    17994087    24495485    22936249    10731132    12537572    12537569    16600911    17550304    17510324    26108605    17204158    15632085    26483478    24945155    20566863    24438588    28327890    25315136    25244985   

EMBL

KZ149928    PZC77489.1    ODYU01006654    SOQ48691.1    NWSH01003518    PCG66179.1    + More
GDQN01004300    JAT86754.1    GAIX01012348    JAA80212.1    KQ461158    KPJ08069.1    KQ459562    KPI99741.1    PYGN01000051    PSN56121.1    NEVH01000618    PNF43180.1    KK852544    KDR21627.1    GDKW01002035    JAI54560.1    ACPB03006195    GAHY01001747    JAA75763.1    GECL01002182    JAP03942.1    GBGD01003570    JAC85319.1    GEDC01000693    JAS36605.1    KQ435827    KOX71930.1    KB632343    ERL93024.1    APGK01058607    BT127314    KB741291    AEE62276.1    ENN70526.1    GL450389    EFN81061.1    AK417831    BAN21046.1    KQ434889    KZC10313.1    KQ971357    EFA08348.1    KQ761453    OAD57543.1    GL442063    EFN63980.1    KZ288487    PBC25230.1    JR039510    AEY58736.1    GBHO01001748    GBHO01001747    GBRD01017225    JAG41856.1    JAG41857.1    JAG48602.1    GEZM01048497    JAV76544.1    ADTU01023014    KK107128    EZA58252.1    GECU01029914    JAS77792.1    KQ761493    OAD57489.1    LKEY01022044    KYN50545.1    GECZ01017402    GECZ01013953    JAS52367.1    JAS55816.1    NNAY01000707    OXU26863.1    GEBQ01002827    JAT37150.1    GL732561    EFX77669.1    KQ976595    KYM79616.1    KQ983176    KYQ46918.1    GDIQ01208621    LRGB01000389    JAK43104.1    KZS19324.1    GDIQ01134898    JAL16828.1    GDIP01243136    JAI80265.1    KK854311    PTY14497.1    BABH01042800    LJIG01022602    KRT79695.1    GDIQ01259872    JAJ91852.1    GFXV01004404    MBW16209.1    GGMR01018986    MBY31605.1    CH480816    EDW47902.1    GDRN01057554    GDRN01057553    JAI65682.1    ABLF02037162    GGMS01003184    MBY72387.1    GAMC01006421    GAMC01006420    GAMC01006418    JAC00138.1    KX531281    ANY27091.1    CH954179    EDV55993.1    CM000362    CM002911    EDX07126.1    KMY93828.1    AE013599    BT001710    CM000158    EDW91061.1    CH933808    EDW10018.1    CH478089    EAT34009.1    CH916367    EDW00914.1    CP012524    ALC41794.1    JRES01000049    KNC34589.1    GDHF01024318    JAI27996.1    DQ440135    ABF18168.1    CH940648    EDW60955.1    CM000071    EAL25193.2    CH479181    EDW32082.1    CH902619    EDV37576.2    OUUW01000001    SPP75288.1    CH963848    EDW73763.1    JXUM01052849    KQ561752    KXJ77634.1    DS231841    EDS34824.1    GFDL01007996    JAV27049.1    GAPW01006124    JAC07474.1    KQ414792    KOC60736.1    JXJN01025955    JXJN01025956    JXJN01025957    DS235250    EEB13985.1    ATLV01027095    KE525423    KFB53898.1    KK114570    KFM62770.1    UFQT01001990    SSX32327.1    JH431957    MNPL01027871    OQR67660.1    AXCM01000968    GAMD01000791    JAB00800.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000245037    UP000235965    UP000027135    + More
UP000015103    UP000053105    UP000030742    UP000019118    UP000192223    UP000008237    UP000076502    UP000007266    UP000000311    UP000242457    UP000005203    UP000005205    UP000053097    UP000078492    UP000002358    UP000215335    UP000000305    UP000078540    UP000075809    UP000076858    UP000005204    UP000001292    UP000007819    UP000079169    UP000008711    UP000000304    UP000000803    UP000002282    UP000009192    UP000008820    UP000001070    UP000092553    UP000037069    UP000192221    UP000008792    UP000091820    UP000001819    UP000008744    UP000007801    UP000268350    UP000007798    UP000069940    UP000249989    UP000002320    UP000053825    UP000078200    UP000092460    UP000009046    UP000030765    UP000075880    UP000054359    UP000192247    UP000075883    UP000095300    UP000075885    UP000095301    UP000076408    UP000075900    UP000075920   

PRIDE

H9JN51   

Pfam

PF07647   SAM_2        + More
PF00536   SAM_1
PF12796   Ank_2

Interpro

IPR001660   SAM        + More
IPR039144   Aveugle-like_SAM_dom       
IPR013761   SAM/pointed_sf       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF47769   SSF47769        + More
SSF48403   SSF48403       

Gene 3D

1.10.150.50     1.25.40.20    

CDD

cd09510  SAM_aveugle-like
cd00204  ANK

ProteinModelPortal

A0A2W1BQX2   A0A2H1W6H4   A0A2A4J2T1   A0A1E1WID3   S4PTB1   A0A0N0PAU7   + More
A0A194Q2G8   A0A2P8ZI11   A0A2J7RQR4   A0A067RD26   A0A0N7Z8Y7   R4G818   A0A0V0G7D0   A0A069DVI1   A0A1B6EFB1   A0A0M8ZVF2   U4UGC3   J3JVP6   A0A1W4WTV8   E2BTE0   R4WQ63   A0A154PEP3   D6WUY3   A0A310SR28   E2ARH1   A0A2A3E0G5   V9IE46   A0A088AK94   A0A0A9Z9B1   A0A1Y1LS78   A0A158NQB1   A0A026WQC8   A0A1B6HSZ2   A0A310SGQ1   A0A151K350   A0A1B6FQ93   K7IQ21   A0A232F8U4   A0A1B6MMI4   E9GS85   A0A195B547   A0A151WGI0   A0A0P5IYV3   A0A0P5PC63   A0A0P4XK11   A0A2R7W450   H9JN51   A0A0T6AX06   A0A0P5FD74   A0A2H8TQD2   A0A2S2PQD1   B4HRN8   A0A0P4WI92   J9JZT8   A0A2S2Q3U3   A0A3Q0JNX5   W8BMX1   A0A1B2AIY1   B3NQT3   B4QFY1   Q8ML92   B4P7N5   B4KNN3   Q16IB6   B4J6L1   A0A0M5JA71   A0A0L0CT42   A0A1W4UJC2   A0A0K8UN29   Q1HRF9   B4LM77   A0A1A9WHW5   Q291B9   B4GAY0   B3ME31   A0A3B0JW41   B4MNS4   A0A182GBC0   B0W577   A0A1Q3FHN9   A0A023EFV0   A0A0L7QQE1   A0A1A9V2M3   A0A1B0C5F3   E0VKS9   A0A084WUK4   A0A182IU65   A0A087TCD1   A0A336MVQ8   T1J8M7   A0A1V9X1Y4   A0A182LT37   A0A1I8Q9C0   A0A182PGD0   A0A1I8M9E0   A0A182YQ94   A0A182RAJ8   A0A182W284   T1DKT4  

PDB

3BS5     E-value=6.20785e-26,     Score=285

KEGG

101740477    no KO assigned | (RefSeq) protein aveugle

GO

GO:0042675   GO:0001751   GO:0009898   GO:0005829   GO:0007173   GO:0001754   GO:0046579   GO:0007601   GO:0007623   GO:0005737   GO:0007165   GO:0005515   GO:0006468   GO:0004190   GO:0006508   GO:0006811   GO:0016020   GO:0003779   GO:0016021  

Subcellular location

Cytoplasm  
Membrane  

Length:

111

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00019

Exp number, first 60 AAs:

7e-05

Total prob of N-in:

0.11858

outside

1  -  111

 

 

Pi

284.429096

Theta

229.277395

Tajima's D

0.764246

CLR

0.323666

CSRT

0.589970501474926

Interpretation

Uncertain