SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01538
Pre Gene Modal
BGIBMGA009072
Annotation
fungal_protease_inhibitor_[Bombyx_mori]
Full name
Fungal protease inhibitor F       + More
IgGFc-binding protein      
Alternative Name
Fcgamma-binding protein antigen
Location in the cell
Mitochondrial   Reliability : 1.256 Nuclear   Reliability : 1.052
 

Sequence

CDS
ATGGCCGCCAAACAATACTTTATCGTGTTCCTGATTGTCGCCCTGATGACTCTTGGTGCCAGCACTGCTGACGATGGGTGTCCCGAGAATGCTCATTGGACTGATGACCCCTGCGCGAAGACCTGCGACGACCCATACTTGACTAACACCGTTTGCATCGCCGCCCTCATTCCAACCTGCCACTGTAACAGCGGCTTAGTCTTCAACGCGGAGAGAAAATGTGTACCCATTTCGGATTGTTAA
Protein
MAAKQYFIVFLIVALMTLGASTADDGCPENAHWTDDPCAKTCDDPYLTNTVCIAALIPTCHCNSGLVFNAERKCVPISDC

Summary

Description
May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa.
Subunit
Interacts with the Fc portion of IgG and with MUC2.
Similarity
Belongs to the protease inhibitor I40 family.
Keywords
Complete proteome   Direct protein sequencing   Disulfide bond   Protease inhibitor   Reference proteome   Secreted   Serine protease inhibitor   Signal   Glycoprotein   Polymorphism   Repeat  
Feature
chain  Fungal protease inhibitor F
sequence variant  In dbSNP:rs34181317.
Pfam
PF01826   TIL        + More
PF00560   LRR_1
PF13855   LRR_8
PF02408   CUB_2
PF01359   Transposase_1
PF00094   VWD
PF12714   TILa
PF17517   IgGFc_binding
PF08742   C8
Interpro
IPR002919   TIL_dom        + More
IPR036084   Ser_inhib-like_sf       
IPR032675   LRR_dom_sf       
IPR016134   Dockerin_dom       
IPR036439   Dockerin_dom_sf       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001611   Leu-rich_rpt       
IPR003366   CUB-like_dom       
IPR001888   Transposase_1       
IPR036388   WH-like_DNA-bd_sf       
IPR014853   Unchr_dom_Cys-rich       
IPR001846   VWF_type-D       
IPR035234   IgGFc-bd_N       
IPR000742   EGF-like_dom       
IPR001007   VWF_dom       
IPR025615   TILa_dom       
IPR003645   Fol_N       
SUPFAM
SSF57567   SSF57567        + More
SSF63446   SSF63446       
Gene 3D

Ontologies

Topology

Subcellular location
Secreted  
SignalP
Position:   1 - 23,         Likelihood:  0.999289
 
 
Length:
80
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
26.80131
Exp number, first 60 AAs:
22.91252
Total prob of N-in:
0.86898
POSSIBLE N-term signal
sequence
inside
1  -  6
TMhelix
7  -  26
outside
27  -  45
TMhelix
46  -  68
inside
69  -  80
 
 

Population Genetic Test Statistics

Pi
146.139951
Theta
153.846756
Tajima's D
-0.157493
CLR
0.200013
CSRT
0.323533823308835
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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