Gene

KWMTBOMO01525  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009063

Annotation

PREDICTED:_uncharacterized_protein_LOC106138821_[Amyelois_transitella]

Location

Bomo_Chr3(+):12856689-12864256      View in EpiBrowser

Full name

Protein quiver      

Alternative Name

Protein sleepless

Location in the cell

Extracellular   Reliability : 4.068

CDS

ATGGCGTACTTTTTCGTTTTCGCGGCTTTGTGCGGTTTTGTGGAGCAAGGCCAAGCAATCGTCTGCTACCAATGCAACAGTCACAACGACTCCCGATGCATCATGGAGGACCTGCCGGACACGCTGCGGCAGCCGTGCAAGTCCACTGACACAATGTGCAGGAAGATCAGCCAGGTCGTGGAGTTCGAGATGAACGGCATGCCCCCGGATAACAGAGTCATCAGAGGGTGCGGGTGGGATGAAAGCAACTACAAGGGCCGTTGCTACCAGCGATCAGGGTTCGGCGGAAGACAAGAGGTCTGCTCGTGCCTGACCGACGGCTGCAACTCAGCGTCGTTACCAGTTATGGGAACAACAGTGATGCTCCTCACGCTAGCACTCCTGAAGTTCTAG

Protein

MAYFFVFAALCGFVEQGQAIVCYQCNSHNDSRCIMEDLPDTLRQPCKSTDTMCRKISQVVEFEMNGMPPDNRVIRGCGWDESNYKGRCYQRSGFGGRQEVCSCLTDGCNSASLPVMGTTVMLLTLALLKF

Description

Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability.

Similarity

Belongs to the quiver family.

Feature

chain  Protein quiver

Uniprot

H9JHR5   A0A2H1VWB3   A0A212EI76   I4DJK2   A0A2A4JEE0   A0A194Q8N6   + More
A0A0N0BEW8   A0A088AI17   A0A1B6G5C7   A0A2A3E728   V9IDV2   A0A1B6M922   U5ES22   A0A1B6IRY3   A0A1B6DU84   E2C3U5   A0A1D1XPR8   A0A195C7K5   A0A067RDT4   A0A195BB15   A0A182QXG4   A0A2M4ASH1   A0A2M4ASN4   A0A158NMU8   F4WTA5   A0A2M4C2S5   A0A2M4C344   Q7Q3Z5   A0A026VTG0   A0A182V1F2   A0A182UGL4   A0A182WU35   A0A1S4GXB8   A0A182HUP7   A0A3L8E3L0   A0A2M4CY83   A0A0K8T9R8   A0A151WUW7   T1DH23   A0A2M3YWC0   A0A0A9WZJ0   A0A1J1ILI9   W5J654   E1ZWA1   A0A2H1VX61   A0A182M2T4   A0A182Y078   A0A2A4JEV1   R4V516   A0A195EXV5   A0A151JBH7   A0A182JQW8   A0A161MMT1   A0A1W4WLC3   A0A182T4F6   A0A182W741   A0A1L8D9Q1   A0A224XNG4   A0A194QQM9   A0A182J2F7   A0A1L8D9R4   A0A1L8D8R4   A0A023EGD7   A0A1L8DA63   A0A0V0GCY8   A0A1L8D9T5   A0A0P4VLU1   U4UHA1   A0A182PMQ3   Q16TE5   A0A084W8B1   A0A2R7W7U9   N6TPH1   A0A023EGA3   B0XBL2   A0A2S2Q2K9   A0A182GLC7   C4WUJ6   A0A0C9Q2S4   A0A1Q3FR88   A0A1L8D7A5   B4JBW6   A0A084W8B0   A0A1W7R5V1   B3MPG0   B4KJN3   B4N155   T1D5A2   T1D356   A0A1Y1JY95   E0VVZ2   A0A1I8PJR3   A0A1Y0F446   A0A0L0CDU8   A0A1B0GFG3   B4LSI1  

Pubmed

19121390    22118469    22651552    26354079    20798317    24845553    + More
21347285    21719571    12364791    24508170    30249741    26823975    25401762    20920257    23761445    25244985    24945155    27129103    23537049    17510324    24438588    26483478    17994087    24330624    28004739    20566863    26108605   

EMBL

BABH01029550    ODYU01004819    SOQ45093.1    AGBW02014682    OWR41192.1    AK401470    + More
BAM18092.1    NWSH01001836    PCG69954.1    KQ459562    KPI99770.1    KQ435819    KOX72511.1    GECZ01012130    JAS57639.1    KZ288365    PBC26841.1    JR040721    JR040722    AEY59260.1    AEY59261.1    GEBQ01007544    JAT32433.1    GANO01005006    JAB54865.1    GECU01018063    JAS89643.1    GEDC01008093    JAS29205.1    GL452364    EFN77331.1    GDJX01023554    JAT44382.1    KQ978231    KYM96146.1    KK852699    KDR18175.1    KQ976529    KYM81741.1    AXCN02000765    GGFK01010398    MBW43719.1    GGFK01010421    MBW43742.1    ADTU01020810    GL888334    EGI62568.1    GGFJ01010418    MBW59559.1    GGFJ01010440    MBW59581.1    AAAB01008964    EAA12565.4    KK108051    EZA46965.1    APCN01002471    QOIP01000001    RLU26985.1    GGFL01006051    MBW70229.1    GBRD01003542    GDHC01001065    JAG62279.1    JAQ17564.1    KQ982721    KYQ51644.1    GAMD01002536    JAA99054.1    GGFF01000093    MBW20560.1    GBHO01029707    JAG13897.1    CVRI01000055    CRL01109.1    ADMH02002111    ETN58883.1    GL434781    EFN74541.1    SOQ45092.1    AXCM01002772    PCG69953.1    KC741139    AGM32963.1    KQ981940    KYN32727.1    KQ979147    KYN22440.1    GEMB01004104    JAR99158.1    GFDF01010881    JAV03203.1    GFTR01002390    JAW14036.1    KQ461175    KPJ07813.1    GFDF01010883    JAV03201.1    GFDF01011225    JAV02859.1    GAPW01005708    JAC07890.1    GFDF01010880    JAV03204.1    GECL01000139    JAP05985.1    GFDF01010882    JAV03202.1    GDKW01003192    JAI53403.1    KB632196    ERL89976.1    CH477651    EAT37771.1    ATLV01021400    KE525317    KFB46455.1    KK854375    PTY15211.1    APGK01056778    KB741277    ENN71115.1    GAPW01005707    JAC07891.1    DS232641    EDS44324.1    GGMS01002707    MBY71910.1    JXUM01071693    JXUM01071694    KQ562679    KXJ75336.1    ABLF02036162    ABLF02036172    AK341094    BAH71566.1    GBYB01008298    JAG78065.1    GFDL01005000    JAV30045.1    GFDF01011731    JAV02353.1    CH916368    EDW04069.1    ATLV01021399    KFB46454.1    GEHC01001089    JAV46556.1    CH902620    EDV31256.1    CH933807    EDW11478.1    CH963920    EDW78036.1    GALA01000623    JAA94229.1    GALA01001383    JAA93469.1    GEZM01097287    JAV54294.1    DS235816    EEB17548.1    KX950846    ARU12056.1    JRES01000536    KNC30367.1    CCAG010006162    CH940649    EDW64803.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000053105    UP000005203    + More
UP000242457    UP000008237    UP000078542    UP000027135    UP000078540    UP000075886    UP000005205    UP000007755    UP000007062    UP000053097    UP000075903    UP000075902    UP000076407    UP000075840    UP000279307    UP000075809    UP000183832    UP000000673    UP000000311    UP000075883    UP000076408    UP000078541    UP000078492    UP000075881    UP000192223    UP000075901    UP000075920    UP000053240    UP000075880    UP000030742    UP000075885    UP000008820    UP000030765    UP000019118    UP000002320    UP000069940    UP000249989    UP000007819    UP000001070    UP000007801    UP000009192    UP000007798    UP000009046    UP000095300    UP000037069    UP000092444    UP000008792   

PRIDE

H9JHR5   

Pfam

PF00439   Bromodomain        + More
PF17064   QVR

Interpro

IPR001487   Bromodomain        + More
IPR036427   Bromodomain-like_sf       
IPR031424   QVR       

SUPFAM

SSF47370   SSF47370       

Gene 3D

1.20.920.10    

ProteinModelPortal

H9JHR5   A0A2H1VWB3   A0A212EI76   I4DJK2   A0A2A4JEE0   A0A194Q8N6   + More
A0A0N0BEW8   A0A088AI17   A0A1B6G5C7   A0A2A3E728   V9IDV2   A0A1B6M922   U5ES22   A0A1B6IRY3   A0A1B6DU84   E2C3U5   A0A1D1XPR8   A0A195C7K5   A0A067RDT4   A0A195BB15   A0A182QXG4   A0A2M4ASH1   A0A2M4ASN4   A0A158NMU8   F4WTA5   A0A2M4C2S5   A0A2M4C344   Q7Q3Z5   A0A026VTG0   A0A182V1F2   A0A182UGL4   A0A182WU35   A0A1S4GXB8   A0A182HUP7   A0A3L8E3L0   A0A2M4CY83   A0A0K8T9R8   A0A151WUW7   T1DH23   A0A2M3YWC0   A0A0A9WZJ0   A0A1J1ILI9   W5J654   E1ZWA1   A0A2H1VX61   A0A182M2T4   A0A182Y078   A0A2A4JEV1   R4V516   A0A195EXV5   A0A151JBH7   A0A182JQW8   A0A161MMT1   A0A1W4WLC3   A0A182T4F6   A0A182W741   A0A1L8D9Q1   A0A224XNG4   A0A194QQM9   A0A182J2F7   A0A1L8D9R4   A0A1L8D8R4   A0A023EGD7   A0A1L8DA63   A0A0V0GCY8   A0A1L8D9T5   A0A0P4VLU1   U4UHA1   A0A182PMQ3   Q16TE5   A0A084W8B1   A0A2R7W7U9   N6TPH1   A0A023EGA3   B0XBL2   A0A2S2Q2K9   A0A182GLC7   C4WUJ6   A0A0C9Q2S4   A0A1Q3FR88   A0A1L8D7A5   B4JBW6   A0A084W8B0   A0A1W7R5V1   B3MPG0   B4KJN3   B4N155   T1D5A2   T1D356   A0A1Y1JY95   E0VVZ2   A0A1I8PJR3   A0A1Y0F446   A0A0L0CDU8   A0A1B0GFG3   B4LSI1  

KEGG

101739676    no KO assigned | (RefSeq) uncharacterized LOC101739676

GO

GO:0016021   GO:0045187   GO:0034235   GO:0048511   GO:0005886   GO:1903818   GO:0030431   GO:0031225   GO:0032222  

Subcellular location

Cell membrane  

SignalP

Position:   1 - 19,         Likelihood:  0.997040

 

 

Length:

130

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.46758

Exp number, first 60 AAs:

0.38646

Total prob of N-in:

0.05552

outside

1  -  130

 

 

Pi

215.81586

Theta

168.933244

Tajima's D

0.621828

CLR

0.031991

CSRT

0.554322283885806

Interpretation

Possibly Positive selection