Gene

KWMTBOMO01523

Pre Gene Modal

BGIBMGA009100

Annotation

PREDICTED:_uncharacterized_protein_LOC101746379_[Bombyx_mori]

Location

Bomo_Chr3(-):12835336-12837528      View in EpiBrowser

Full name

Protein quiver      

Alternative Name

Protein sleepless

Location in the cell

Extracellular   Reliability : 3.543

CDS

ATGAAGCTGGTAACATCGATCCGTTGCTACGAATGCAGCAGCGCGAACAATACAATGTGCTTGGAGCCGGCCTTATACGACGCCGAGACGCTGGACAAGTACCTGCCGACCACCCACTGCGGAAGTGGAGTCGTATCTTCAGGACACCACGCCTTCTTCTGCAGGAAGATAATGCAGACCATATTCCACAAAGGCTACGAACCGGACGTTCGGGTGACCAGAACTTGTGGTTGGATACGTCATCACCGCGACTGTTACATGGCGGACAATGAAGACCATTTGGAGACCGTGTGCCAATGTTTCACAGATGACTGTAATAGGGCGCACGGCGTCCATCCTGTTCGAATGATGGGAAGCATCGCCCTCTTGTTGCTATTAATAAGTTTATCATAA

Protein

MKLVTSIRCYECSSANNTMCLEPALYDAETLDKYLPTTHCGSGVVSSGHHAFFCRKIMQTIFHKGYEPDVRVTRTCGWIRHHRDCYMADNEDHLETVCQCFTDDCNRAHGVHPVRMMGSIALLLLLISLS

Description

Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability.

Similarity

Belongs to the quiver family.

Feature

chain  Protein quiver

Uniprot

H9JHV2   A0A2H1VWH0   A0A2A4JDV0   A0A194QS56   I4DL76   A0A194Q2K0   + More
A0A212EI56   A0A2A4J3C9   A0A2H1X2E0   A0A2H1WLM6   A0A194PXY0   A0A194QQN6   A0A194RC22   A9NQN4   A0A2H1VW95   A0A2A4JCZ3   A0A0L7KP16   A0A182GLC5   A0A1W7R7F3   Q16TE3   A0A1B6I5Y0   A0A1S4FPR5   A0A182SJ17   A0A1B6HLW2   A0A1B6JCB4   A0A2R7W659   A0A1Y0F444   A0A1B6HRF6   A0A1B6ID59   A0A1B6M2H9   A0A1B6EN97   A0A1B6EPQ6   A0A1B6EW33   A0A1S3DKU4   A0A182QPV9   A0A0A9XZB9   A0A182RZU7   A0A182Y080   A0A1B6M3F7   A0A1B6EBK2   A0A1B6M7B4   A0A0K8ST25   A0A146L5R6   A0A0A9ZFY9   A0A0K8SE02   A0A182NUD1   A0A182W740   A0A146M3T3   A0A067RGE3   A0A0A9WYG5   A0A170XS60   A0A182PMQ4   A0A139WDC4   A0A1S6GLF2   A0A194Q8N6   B4KJN4   D6WX56   A0A224XNC3   A0A182MBQ4   A0A194QQM9   A0A1S4HDK6   A0A139WDI4   A0A0M4E4Q1   A0A2R7W7U9   A0A0Q9WPX7   B0XBK8   E2C3U5   A0A023EGD7   A0A2R7W6A1   B4JBW7   A0A182GLC7   A0A1W7R5V1   A0A0K8T9R8   A0A1B6DU84   E1ZWA1   A0A182L1I4   Q16TE5   A0A0A9WZJ0   A0A3L8E3L0   A0A023EGA3   A0A158NMU8   A0A026VTG0   A0A0V0GCY8   A0A182HUP6   A0A2R7W661   A0A131ZXE7   A0A1Q3FR88   A0A195BB15   B3MPF8   A0A195C7K5   A0A1J1IGR7  

Pubmed

19121390    26354079    22651552    22118469    18854048    26227816    + More
26483478    17510324    25401762    25244985    26823975    24845553    18362917    19820115    28043022    17994087    12364791    20798317    24945155    20966253    30249741    21347285    24508170    26555130   

EMBL

BABH01029552    ODYU01004819    SOQ45096.1    NWSH01001836    PCG69956.1    KQ461175    + More
KPJ07815.1    AK402044    BAM18666.1    KQ459562    KPI99771.1    AGBW02014682    OWR41193.1    NWSH01003318    PCG66565.1    ODYU01012968    SOQ59530.1    ODYU01009460    SOQ53917.1    KQ459585    KPI98187.1    KPJ07812.1    KQ460627    KPJ13456.1    EF083605    ABK22945.1    SOQ45095.1    PCG69955.1    JTDY01007995    KOB64811.1    JXUM01071690    KQ562679    KXJ75334.1    GEHC01000630    JAV47015.1    CH477651    EAT37773.1    GECU01025374    JAS82332.1    GECU01032052    JAS75654.1    GECU01010872    JAS96834.1    KK854375    PTY15214.1    KX950850    ARU12060.1    GECU01037545    GECU01031949    GECU01030473    GECU01028717    GECU01024976    GECU01020943    GECU01014029    GECU01006896    JAS70161.1    JAS75757.1    JAS77233.1    JAS78989.1    JAS82730.1    JAS86763.1    JAS93677.1    JAT00811.1    GECU01030423    GECU01030128    GECU01025081    GECU01022832    GECU01016958    GECU01016104    GECU01010534    GECU01009974    GECU01002747    JAS77283.1    JAS77578.1    JAS82625.1    JAS84874.1    JAS90748.1    JAS91602.1    JAS97172.1    JAS97732.1    JAT04960.1    GEBQ01009831    JAT30146.1    GECZ01030355    JAS39414.1    GECZ01029889    JAS39880.1    GECZ01027620    JAS42149.1    AXCN02000764    GBHO01019396    GBHO01019395    JAG24208.1    JAG24209.1    GEBQ01009512    JAT30465.1    GEDC01002044    JAS35254.1    GEBQ01008194    JAT31783.1    GBRD01009366    JAG56458.1    GDHC01014876    JAQ03753.1    GBHO01000140    GDHC01011193    JAG43464.1    JAQ07436.1    GBRD01014309    JAG51517.1    GDHC01004947    JAQ13682.1    KK852699    KDR18174.1    GBHO01031143    GBRD01007381    JAG12461.1    JAG58440.1    GEMB01004103    JAR99159.1    KQ971361    KYB25914.1    KY314245    AQS22679.1    KPI99770.1    CH933807    EDW11479.1    EFA08039.1    GFTR01002430    JAW13996.1    AXCM01002772    KPJ07813.1    AAAB01008964    KYB25915.1    CP012523    ALC38908.1    PTY15211.1    CH963852    KRF98260.1    DS232641    EDS44320.1    GL452364    EFN77331.1    GAPW01005708    JAC07890.1    PTY15212.1    CH916368    EDW04070.1    JXUM01071693    JXUM01071694    KXJ75336.1    GEHC01001089    JAV46556.1    GBRD01003542    GDHC01001065    JAG62279.1    JAQ17564.1    GEDC01008093    JAS29205.1    GL434781    EFN74541.1    EAT37771.1    GBHO01029707    JAG13897.1    QOIP01000001    RLU26985.1    GAPW01005707    JAC07891.1    ADTU01020810    KK108051    EZA46965.1    GECL01000139    JAP05985.1    APCN01002470    APCN01002471    PTY15213.1    JXLN01005383    KPM03528.1    GFDL01005000    JAV30045.1    KQ976529    KYM81741.1    CH902620    EDV31254.1    KQ978231    KYM96146.1    CVRI01000050    CRK99445.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000069940    UP000249989    UP000008820    UP000075901    UP000079169    UP000075886    UP000075900    UP000076408    UP000075884    UP000075920    UP000027135    UP000075885    UP000007266    UP000009192    UP000075883    UP000092553    UP000007798    UP000002320    UP000008237    UP000001070    UP000000311    UP000075882    UP000279307    UP000005205    UP000053097    UP000075840    UP000078540    UP000007801    UP000078542    UP000183832   

PRIDE

H9JHV2   

Pfam

PF17064   QVR        + More
PF00439   Bromodomain

Interpro

IPR031424   QVR        + More
IPR001487   Bromodomain       
IPR036427   Bromodomain-like_sf       

SUPFAM

SSF47370   SSF47370       

Gene 3D

1.20.920.10    

ProteinModelPortal

H9JHV2   A0A2H1VWH0   A0A2A4JDV0   A0A194QS56   I4DL76   A0A194Q2K0   + More
A0A212EI56   A0A2A4J3C9   A0A2H1X2E0   A0A2H1WLM6   A0A194PXY0   A0A194QQN6   A0A194RC22   A9NQN4   A0A2H1VW95   A0A2A4JCZ3   A0A0L7KP16   A0A182GLC5   A0A1W7R7F3   Q16TE3   A0A1B6I5Y0   A0A1S4FPR5   A0A182SJ17   A0A1B6HLW2   A0A1B6JCB4   A0A2R7W659   A0A1Y0F444   A0A1B6HRF6   A0A1B6ID59   A0A1B6M2H9   A0A1B6EN97   A0A1B6EPQ6   A0A1B6EW33   A0A1S3DKU4   A0A182QPV9   A0A0A9XZB9   A0A182RZU7   A0A182Y080   A0A1B6M3F7   A0A1B6EBK2   A0A1B6M7B4   A0A0K8ST25   A0A146L5R6   A0A0A9ZFY9   A0A0K8SE02   A0A182NUD1   A0A182W740   A0A146M3T3   A0A067RGE3   A0A0A9WYG5   A0A170XS60   A0A182PMQ4   A0A139WDC4   A0A1S6GLF2   A0A194Q8N6   B4KJN4   D6WX56   A0A224XNC3   A0A182MBQ4   A0A194QQM9   A0A1S4HDK6   A0A139WDI4   A0A0M4E4Q1   A0A2R7W7U9   A0A0Q9WPX7   B0XBK8   E2C3U5   A0A023EGD7   A0A2R7W6A1   B4JBW7   A0A182GLC7   A0A1W7R5V1   A0A0K8T9R8   A0A1B6DU84   E1ZWA1   A0A182L1I4   Q16TE5   A0A0A9WZJ0   A0A3L8E3L0   A0A023EGA3   A0A158NMU8   A0A026VTG0   A0A0V0GCY8   A0A182HUP6   A0A2R7W661   A0A131ZXE7   A0A1Q3FR88   A0A195BB15   B3MPF8   A0A195C7K5   A0A1J1IGR7  

KEGG

101746379    no KO assigned | (RefSeq) uncharacterized LOC101746379

GO

GO:0016021   GO:0016874   GO:0005886   GO:0048511   GO:0034235   GO:0045187   GO:0032222   GO:0031225   GO:1903818   GO:0030431  

Subcellular location

Cell membrane  

Length:

130

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.69136

Exp number, first 60 AAs:

0.04245

Total prob of N-in:

0.47672

outside

1  -  130

 

 

Pi

195.475431

Theta

147.964139

Tajima's D

1.144613

CLR

0.031991

CSRT

0.699965001749912

Interpretation

Possibly Positive selection