Gene

KWMTBOMO01510

Pre Gene Modal

BGIBMGA009059

Annotation

PREDICTED:_slowpoke-binding_protein_[Plutella_xylostella]

Location

Bomo_Chr3(+):12598060-12603430      View in EpiBrowser

Full name

Slowpoke-binding protein      

Location in the cell

Cytoplasmic   Reliability : 1.101 Extracellular   Reliability : 1.21 Mitochondrial   Reliability : 1.137

CDS

ATGGAACAAGAGAATTCTGAGCGTGCACCTCTCGTGGCACAGAAGATAGACTCCCTGGCGAAATTGCTGTTCAACAAATCCCTTATTGGCACGGGCTCTGGTAAATCATCTCCATCAGAACCGACAGCTTCGCCAAGAGCTGGCGATCGTTCTATGGAAAATTCGGCTGCTCTAGCAATATGTACAGAATATTTGTCACAATCTTCAAGATATGCTTTAATTTCTCAGCTCGGAGCGATTGGGTCACGACCGAATAAACATTGGTTTGCTATCCACGACAATTCCATTAAAACTGACAGACTGCTAACCCTGATGCCTCTAACAAATAAATGCCCGATAGAACAGGGCGACCGTTCTAAAGCCCTGATAATGGAATTATTTCGGGCCCTCCACCATCCATATATATATCCAGTACTTGACCTGGAAATGTGTAATGGACACGCACTGACCGTCTTACCATTTAATGCCAGGGGGAGTCTGAAAGATCTTATTTATAAGAGTACTTGGAATGACGAGTACGCCCGCAAGTGCGGCTCGTTGGGCACGGGGCTCCCGGCGTGGCAGGTGGCGAGGTTTGGGCGACAGATGCTGGAAGGCCTCCTCTTTCTAAAGGAGAAGGGTTTTCCGCCCTTCCGACATCTACACTCGGGCAACGTTGTCGTGCAGAACGGGGTTGCACGTATATGTGGATTGGAGAACACGTTGATCGGGGCCCTCCCGCGGTGTCCCATAGCGTTGGCCGCCCAGCTGGAGGTCGTGGAGGCTCTGTCCCTCGGACACGTGCTGTTTGAGATGTGTGCCGGCACTGAGATCGACCTCGCTCTGTTGCCCGATCTCACGCCGACGTATCCGAACGTCGTCGAGATCATCGAACAGATCTTCGGTCCGCGGACCCCGACGCTGCACGAGCTGCTCCTCTGTGAGCTGTTCCGGAAGATCGACCTTCGCGAGATGAAGGGATCTTGCTTACCGGTAACGTCATTAAGAAACAACTTTATGTAA

Protein

MEQENSERAPLVAQKIDSLAKLLFNKSLIGTGSGKSSPSEPTASPRAGDRSMENSAALAICTEYLSQSSRYALISQLGAIGSRPNKHWFAIHDNSIKTDRLLTLMPLTNKCPIEQGDRSKALIMELFRALHHPYIYPVLDLEMCNGHALTVLPFNARGSLKDLIYKSTWNDEYARKCGSLGTGLPAWQVARFGRQMLEGLLFLKEKGFPPFRHLHSGNVVVQNGVARICGLENTLIGALPRCPIALAAQLEVVEALSLGHVLFEMCAGTEIDLALLPDLTPTYPNVVEIIEQIFGPRTPTLHELLLCELFRKIDLREMKGSCLPVTSLRNNFM

Description

Regulator of calcium-activated channel Slo. Increases or decreases the voltage sensitivity of Slo, depending on the absence or presence of 14-3-3-zeta in the complex, respectively.

Subunit

Interacts specifically with Slo; which activates Slo activity. Interacts with 14-3-3-zeta when phosphorylated. Forms a heterotetrameric complex containing phosphorylated Slob, Slo and 14-3-3-zeta, which represses Slo activity due to the indirect interaction between Slo and 14-3-3-zeta.

Similarity

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Alternative splicing   Complete proteome   Cytoplasm   Phosphoprotein   Reference proteome  

Feature

chain  Slowpoke-binding protein
splice variant  In isoform 2.

Uniprot

H9JHR1   A0A2A4K9A7   A0A2H1X060   A0A0N0PBF6   A0A212FEP6   A0A194Q2J6   + More
A0A0L7LD07   A0A2J7QG36   Q16N23   A0A0A9X116   A0A0A9WTP4   A0A0A9WSM4   A0A1S4G7X8   A0A0A9YA77   A0A224XQB9   A0A084VM44   A0A0H2UI67   A0A0H2UI68   A0A1B6EGS4   Q7QGF6   A0A182TKB3   A0A182V240   A0A1B6DUY8   A0A1B6CHF9   A0A023F453   E0VDX1   A0A182IZA6   A0A182H9F0   A0A1J1I0G5   A0A182Q6N5   A0A139WDB5   A0A2P8YU62   A0A182M5U8   T1PCB0   A0A1I8M9D9   B4MDD7   B4HY81   A4V0D4   Q8IPH9   D1Z388   A0A0Q5WBC2   A0A310SK14   B4Q5R3   B4KFQ8   Q8IPH9-2   M9MRD7   A0A0J9TI07   A0A0R1DJ98   A0A1W4XS40   A0A0T6BB48   A0A0Q9XCU7   B3N6L8   E2BIW1   A0A195F1T8   A0A1I8PFQ2   A0A1I8M9D8   A0A1I8M9E1   A0A0Q9WX09   A0A3B0K824   A0A0J9TI14   B4NZI8   A0A182X0N0   A0A182HGB6   A0A182P9I6   A0A026VTA3   A0A195E855   A0A1W4XS85   A0A3B0JC89   J9K366   A0A0P5BX39   A0A3L8DLA3   A0A0P5LC00   A0A0N8B404   A0A0P5V699   F4WTP6   A0A0P6A3X5   A0A0Q5WBV0   A0A0P6ENF6   A0A158NG48   A0A0Q9XC71   A0A151I1H1   A0A1B0F942   W5JDG2   A0A0P5MFQ3   A0A0Q9X3X6   A0A0C9RBI7   A0A154P8Z0   M9PF34   A0A0P6EUR2   A0A0Q9X246   A0A0P5XQJ9   A0A0P5XK81   T1PL86   A0A1I8PFG4   E2AQH7   A0A1Y1MP42   A0A034V1S8   A0A0Q5WMW6   A0A0P5RRY7   A0A0P6EIX9  

Pubmed

19121390    26354079    22118469    26227816    17510324    25401762    + More
24438588    12364791    14747013    17210077    25474469    20566863    26483478    18362917    19820115    29403074    25315136    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    9539129    12537569    10230800    11719206    14529710    18057021    22936249    17550304    20798317    24508170    30249741    21719571    21347285    20920257    23761445    28004739    25348373   

EMBL

BABH01029573    BABH01029574    BABH01029575    BABH01029576    NWSH01000043    PCG80320.1    + More
ODYU01012377    SOQ58657.1    KQ460941    KPJ10584.1    AGBW02008911    OWR52212.1    KQ459562    KPI99787.1    JTDY01001616    KOB73352.1    NEVH01014836    PNF27549.1    CH477842    EAT35730.1    GBHO01032811    GBHO01032809    GBHO01021871    JAG10793.1    JAG10795.1    JAG21733.1    GBHO01032813    JAG10791.1    GBHO01032810    JAG10794.1    GBHO01014540    JAG29064.1    GFTR01006083    JAW10343.1    ATLV01014577    KE524975    KFB39038.1    ACPB03012487    ACPB03012488    ACPB03012489    ACPB03012490    ACPB03012491    GEDC01000173    JAS37125.1    AAAB01008835    EAA05750.4    GEDC01007808    JAS29490.1    GEDC01024495    JAS12803.1    GBBI01002938    JAC15774.1    DS235088    EEB11577.1    JXUM01120555    JXUM01120556    KQ566405    KXJ70156.1    CVRI01000038    CRK93839.1    AXCN02000844    KQ971361    KYB25940.1    PYGN01000357    PSN47784.1    AXCM01000140    KA646324    AFP60953.1    CH940661    EDW71198.1    CH480818    EDW52011.1    AE014134    AAF52535.1    AF051162    BT021228    AY060721    BT120024    ACZ98476.1    CH954177    KQS70710.1    KQS70712.1    KQ761783    OAD57026.1    CM000361    EDX04109.1    CH933807    EDW11023.2    ADV36960.1    CM002910    KMY88805.1    KMY88808.1    CM000157    KRJ97350.1    KRJ97355.1    LJIG01002805    KRT84135.1    KRG02498.1    EDV59234.2    GL448535    EFN84393.1    KQ981864    KYN34137.1    KRF85534.1    OUUW01000004    SPP79678.1    KMY88810.1    EDW87737.2    APCN01004212    KK108395    EZA46716.1    KQ979568    KYN21007.1    SPP79675.1    ABLF02019043    GDIP01194071    JAJ29331.1    QOIP01000006    RLU21161.1    GDIQ01176390    JAK75335.1    GDIQ01215027    JAK36698.1    GDIP01119725    JAL83989.1    GL888341    EGI62467.1    GDIQ01153708    GDIP01036689    GDIP01035197    JAK98017.1    JAM68518.1    KQS70708.1    GDIQ01060138    JAN34599.1    ADTU01014963    KRG02500.1    KQ976580    KYM79960.1    ADMH02001847    ETN60910.1    GDIQ01156301    JAK95424.1    KRG02501.1    GBYB01010497    JAG80264.1    KQ434831    KZC07844.1    AGB92747.1    GDIQ01057735    JAN37002.1    CH963852    KRF98284.1    GDIP01070876    JAM32839.1    GDIP01070877    JAM32838.1    KA649496    AFP64125.1    GL441764    EFN64325.1    GEZM01030208    GEZM01030205    GEZM01030202    GEZM01030201    GEZM01030200    GEZM01030199    GEZM01030198    GEZM01030197    GEZM01030195    GEZM01030191    GEZM01030186    GEZM01030185    GEZM01030182    GEZM01030181    JAV85716.1    GAKP01023246    JAC35710.1    KQS70706.1    GDIQ01115417    JAL36309.1    GDIQ01062131    JAN32606.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000037510    + More
UP000235965    UP000008820    UP000030765    UP000015103    UP000007062    UP000075902    UP000075903    UP000009046    UP000075880    UP000069940    UP000249989    UP000183832    UP000075886    UP000007266    UP000245037    UP000075883    UP000095301    UP000008792    UP000001292    UP000000803    UP000008711    UP000000304    UP000009192    UP000002282    UP000192223    UP000008237    UP000078541    UP000095300    UP000268350    UP000076407    UP000075840    UP000075885    UP000053097    UP000078492    UP000007819    UP000279307    UP000007755    UP000005205    UP000078540    UP000092443    UP000000673    UP000076502    UP000007798    UP000000311   

PRIDE

H9JHR1    Q8IPH9    D1Z388   

Pfam

PF00153   Mito_carr

Interpro

IPR018108   Mitochondrial_sb/sol_carrier        + More
IPR023395   Mt_carrier_dom_sf       
IPR011009   Kinase-like_dom_sf       
IPR000719   Prot_kinase_dom       

SUPFAM

SSF103506   SSF103506        + More
SSF56112   SSF56112       

Gene 3D

1.50.40.10    

ProteinModelPortal

H9JHR1   A0A2A4K9A7   A0A2H1X060   A0A0N0PBF6   A0A212FEP6   A0A194Q2J6   + More
A0A0L7LD07   A0A2J7QG36   Q16N23   A0A0A9X116   A0A0A9WTP4   A0A0A9WSM4   A0A1S4G7X8   A0A0A9YA77   A0A224XQB9   A0A084VM44   A0A0H2UI67   A0A0H2UI68   A0A1B6EGS4   Q7QGF6   A0A182TKB3   A0A182V240   A0A1B6DUY8   A0A1B6CHF9   A0A023F453   E0VDX1   A0A182IZA6   A0A182H9F0   A0A1J1I0G5   A0A182Q6N5   A0A139WDB5   A0A2P8YU62   A0A182M5U8   T1PCB0   A0A1I8M9D9   B4MDD7   B4HY81   A4V0D4   Q8IPH9   D1Z388   A0A0Q5WBC2   A0A310SK14   B4Q5R3   B4KFQ8   Q8IPH9-2   M9MRD7   A0A0J9TI07   A0A0R1DJ98   A0A1W4XS40   A0A0T6BB48   A0A0Q9XCU7   B3N6L8   E2BIW1   A0A195F1T8   A0A1I8PFQ2   A0A1I8M9D8   A0A1I8M9E1   A0A0Q9WX09   A0A3B0K824   A0A0J9TI14   B4NZI8   A0A182X0N0   A0A182HGB6   A0A182P9I6   A0A026VTA3   A0A195E855   A0A1W4XS85   A0A3B0JC89   J9K366   A0A0P5BX39   A0A3L8DLA3   A0A0P5LC00   A0A0N8B404   A0A0P5V699   F4WTP6   A0A0P6A3X5   A0A0Q5WBV0   A0A0P6ENF6   A0A158NG48   A0A0Q9XC71   A0A151I1H1   A0A1B0F942   W5JDG2   A0A0P5MFQ3   A0A0Q9X3X6   A0A0C9RBI7   A0A154P8Z0   M9PF34   A0A0P6EUR2   A0A0Q9X246   A0A0P5XQJ9   A0A0P5XK81   T1PL86   A0A1I8PFG4   E2AQH7   A0A1Y1MP42   A0A034V1S8   A0A0Q5WMW6   A0A0P5RRY7   A0A0P6EIX9  

KEGG

101746797    K17543 PX domain-containing protein kinase-like protein | (RefSeq) slowpoke-binding protein

GO

GO:0016021   GO:0005524   GO:0004672   GO:0005886   GO:0032780   GO:0042391   GO:0005737   GO:0043271   GO:0016301   GO:0016740   GO:0050804   GO:0042594   GO:0007274  

Subcellular location

Cytoplasm  

Length:

333

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0117

Exp number, first 60 AAs:

0.00022

Total prob of N-in:

0.03112

outside

1  -  333

 

 

Pi

247.299531

Theta

183.878166

Tajima's D

1.140859

CLR

0

CSRT

0.697215139243038

Interpretation

Uncertain