Gene

KWMTBOMO01502  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009107

Annotation

glutathione_S-transferase_sigma_2_[Bombyx_mori]

Location

Bomo_Chr3(-):12547927-12558419      View in EpiBrowser

Full name

Glutathione S-transferase 2       + More
Glutathione S-transferase      

Alternative Name

GST class-sigma

Location in the cell

Cytoplasmic   Reliability : 2.627

CDS

ATGCCGAACGTTAAGTTCTACTATTTCCCCGTCAAGGCCCTCGGCGAGAGCCAGAGGCTGCTGCTGGCTTACGGCGGCCAGGAGTTCGAAGACAATCGCATTTCATCTGAAAACTGGCCAGAATTCAAACCTAAGACTCCGTTCGGTCAGATGCCGGTGCTGGAAATCGACGGCAAGCAGTACGCTCAGAGCACCGCCATCTGCAGGTACCTCGGTCGCAAGTACGGGCTCGCCGGGGCCAATGACGAGGAGGCCTTCGAGATCGACCAGAACGTGGAGTTCCTGAACGACATTCGCGCCAGTGCCGCATCGGTCCACTACGAGAAAGACGAGGCCGTCAAAGCTAAGAAGAAGGCGGAACTGGAGGAGACTAAATACCCGTTCTTTTTCGAGAAACTCAATGAGATACTGACGAAGAACAACGGTCATATCGCGCTTGGCAAGTTGACCTGGGGCGACTTTGTGTACGCCGGCATGTACGACTACCTGAAGGCGATGCTCCAGAAGCCGGATCTGGAGCAGAAGTACCCGGCCTTCAGGAAGCCCATCGAGGCGGTCCTGGCCATCCCCAAGGTCAAGGCCTACGTCGACGCGGCACCGAGAACAGAACTTTAA

Protein

MPNVKFYYFPVKALGESQRLLLAYGGQEFEDNRISSENWPEFKPKTPFGQMPVLEIDGKQYAQSTAICRYLGRKYGLAGANDEEAFEIDQNVEFLNDIRASAASVHYEKDEAVKAKKKAELEETKYPFFFEKLNEILTKNNGHIALGKLTWGDFVYAGMYDYLKAMLQKPDLEQKYPAFRKPIEAVLAIPKVKAYVDAAPRTEL

Catalytic Activity

glutathione + RX = a halide anion + an S-substituted glutathione + H(+)

Subunit

Homodimer.

Similarity

Belongs to the GST superfamily.
Belongs to the GST superfamily. Sigma family.

Keywords

Transferase   Alternative splicing   Complete proteome   Reference proteome  

Feature

chain  Glutathione S-transferase 2
splice variant  In isoform B.

Uniprot

Q5CCJ4   Q4ACU7   D3JYQ6   S4PA35   A0A2L1CF21   A0A0A7KLG0   + More
A0A1P8L0T1   A0A165G1C4   A0A3G1ZLD3   D3YEX2   Q7Z1E3   C6ZJZ8   A0A075X8Y1   Q6F436   A0A1W6I4L5   A0A2R4N9Y3   H9JHV8   A0A0N1ICL7   S4NSB8   P46429   A0A0K8TV03   A0A194Q8Q4   I4DJV2   O76783   A0A2H1VZ98   A0A194Q450   A0A3G1ZLD1   A0A0N0PBF2   A0A2A4J6M7   F6KX43   F6KX42   A0A3G1ZLC8   A0A1P8L0T6   H9NAT8   I4DMZ0   I4DL77   A0A194Q2M0   A0A0K8T4L2   B2BNZ2   D7S006   A0A0K8TUE8   D7S007   A0A2H1WRZ9   A0A2H1WRQ5   A0A2A4J778   D7S004   A0A212FJP1   D7S008   A0A212FJP7   F6KX44   A0A2A4J0N1   A0A1P8L0V1   D7S005   A0A3G1ZLD0   I4DL78   A0A0K8TUF1   A0A212FJR7   A0A0K8TUG2   A0A2H1VVM4   A0A194Q461   A0A2P0XJ18   A0A077D6F7   A0A0N0PBF3   A0A194RRD8   A0A0D3M5T8   A0A1L8E4S0   A8CWB8   A8CAE7   A0A1W4XE39   F4MI28   A0A2J7R389   Q16P79   A0A2A4J5X4   A0A194Q378   A0A067RMR4   A0A2U9K4C4   A0A0C9QT46   A0A1W4XNC8   Q16P80   E2AX16   A0A023EME7   A0A182H3T8   A0A0K8TUE4   A0A0K8TUF3   A0A1J1I2E5   A0A1Q3FUT1   A0A195FTC9   A0A2H1W020   A0A0N1PH59   A0A1Q3FSB3   M9VAC6   A0A1Q3FRY5   P46428-2   A0A182VJ04   A0A182XAY9   A0A182HX63   B0WFX0   A0A2P8ZI29   A0A182RRD5   A0A182W3P5  

EC Number

2.5.1.18

Pubmed

17284839    19121390    23458683    23622113    30319435    22299369    + More
20364407    26354079    7742833    26017144    22651552    21605564    18651917    22118469    18194529    17760985    21569254    17510324    24845553    29234290    20798317    24945155    26483478    26369729    25480347    28767183    9087540    12364791    29403074   

EMBL

BABH01029577    KF743058    AB206971    AHC69716.1    BAD91107.1    AB223045    + More
BAE16754.1    GU338052    ADC32118.1    GAIX01003429    JAA89131.1    MF521977    AVC05621.1    KM433693    AIZ46905.1    KX229716    APW77577.1    KT984985    AMY26653.1    MH177606    AYM01178.1    GU453917    ADD14027.1    AY297161    DQ862466    AAP50848.1    ABI15775.1    EU912434    ACK75952.1    KF482967    AIH07591.1    AB180454    BAD26698.1    KX500037    ARM39007.1    MF503495    AVX32553.1    BABH01029576    KQ460941    KPJ10579.1    GAIX01014167    JAA78393.1    L32092    GCVX01000112    JAI18118.1    KQ459562    KPI99790.1    AK401570    BAM18192.1    AF082570    AAC34097.1    ODYU01005380    SOQ46161.1    KPI99789.1    MH177604    AYM01176.1    KPJ10581.1    NWSH01002798    PCG67519.1    HQ667937    AEG75843.1    HQ667936    AEG75842.1    MH177603    AYM01175.1    KX229717    APW77578.1    JQ236852    AFF27579.1    AK402658    BAM19280.1    AK402045    BAM18667.1    KPI99791.1    GBRD01005353    JAG60468.1    EF591059    ABU88426.1    HM209429    ADI32890.1    GCVX01000116    JAI18114.1    HM209430    ADI32891.1    ODYU01010552    SOQ55742.1    SOQ55741.1    PCG67518.1    HM209427    ADI32888.1    AGBW02008248    OWR53951.1    HM209431    ADI32892.1    OWR53952.1    HQ667938    AEG75844.1    NWSH01004458    PCG65084.1    KX229719    APW77580.1    HM209428    ADI32889.1    MH177605    AYM01177.1    AK402046    BAM18668.1    GCVX01000111    JAI18119.1    OWR53950.1    GCVX01000113    JAI18117.1    ODYU01004709    SOQ44879.1    KPI99799.1    KY661341    AVA17428.1    KM099188    AIL29318.1    KPJ10574.1    KQ459989    KPJ18606.1    KJ468619    AIB07720.1    GFDF01000357    JAV13727.1    AJWK01030929    AJWK01030930    EU124611    ABV60329.1    EU045339    ABV44736.1    EZ617709    ADH94602.1    NEVH01007822    PNF35302.1    CH477792    EAT36155.2    PCG67517.1    KPI99798.1    KK852417    KDR24333.1    MG387112    AWS20692.1    GBYB01003772    JAG73539.1    EAT36154.2    GL443495    EFN62036.1    GAPW01004109    JAC09489.1    JXUM01108106    JXUM01108107    KQ565202    KXJ71233.1    GDAI01000043    JAI17560.1    GCVX01000123    JAI18107.1    CVRI01000036    CRK93022.1    GFDL01003842    JAV31203.1    KQ981276    KYN43676.1    SOQ46162.1    KPJ10578.1    GFDL01004679    JAV30366.1    KC161213    KJ913696    MF036029    MF036052    AGJ76541.1    AIL33467.1    AST11608.1    AST11631.1    GFDL01004685    JAV30360.1    L07880    AAAB01008849    APCN01005145    DS231921    EDS26505.1    PYGN01000050    PSN56155.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    UP000092461    + More
UP000192223    UP000235965    UP000008820    UP000027135    UP000000311    UP000069940    UP000249989    UP000183832    UP000078541    UP000007062    UP000075903    UP000076407    UP000075840    UP000002320    UP000245037    UP000075900    UP000075920   

PRIDE

Q5CCJ4    Q7Z1E3    H9JHV8    P46429   

Pfam

PF02798   GST_N        + More
PF14497   GST_C_3
PF01454   MAGE
PF01239   PPTA

Interpro

IPR010987   Glutathione-S-Trfase_C-like        + More
IPR040079   Glutathione_S-Trfase       
IPR004045   Glutathione_S-Trfase_N       
IPR004046   GST_C       
IPR036249   Thioredoxin-like_sf       
IPR036282   Glutathione-S-Trfase_C_sf       
IPR041899   MAGE_WH2       
IPR002190   MHD_dom       
IPR041898   MAGE_WH1       
IPR003080   GST_alpha       
IPR002088   Prenyl_trans_a       

SUPFAM

SSF47616   SSF47616        + More
SSF52833   SSF52833       

Gene 3D

1.10.10.1200     1.10.10.1210    

ProteinModelPortal

Q5CCJ4   Q4ACU7   D3JYQ6   S4PA35   A0A2L1CF21   A0A0A7KLG0   + More
A0A1P8L0T1   A0A165G1C4   A0A3G1ZLD3   D3YEX2   Q7Z1E3   C6ZJZ8   A0A075X8Y1   Q6F436   A0A1W6I4L5   A0A2R4N9Y3   H9JHV8   A0A0N1ICL7   S4NSB8   P46429   A0A0K8TV03   A0A194Q8Q4   I4DJV2   O76783   A0A2H1VZ98   A0A194Q450   A0A3G1ZLD1   A0A0N0PBF2   A0A2A4J6M7   F6KX43   F6KX42   A0A3G1ZLC8   A0A1P8L0T6   H9NAT8   I4DMZ0   I4DL77   A0A194Q2M0   A0A0K8T4L2   B2BNZ2   D7S006   A0A0K8TUE8   D7S007   A0A2H1WRZ9   A0A2H1WRQ5   A0A2A4J778   D7S004   A0A212FJP1   D7S008   A0A212FJP7   F6KX44   A0A2A4J0N1   A0A1P8L0V1   D7S005   A0A3G1ZLD0   I4DL78   A0A0K8TUF1   A0A212FJR7   A0A0K8TUG2   A0A2H1VVM4   A0A194Q461   A0A2P0XJ18   A0A077D6F7   A0A0N0PBF3   A0A194RRD8   A0A0D3M5T8   A0A1L8E4S0   A8CWB8   A8CAE7   A0A1W4XE39   F4MI28   A0A2J7R389   Q16P79   A0A2A4J5X4   A0A194Q378   A0A067RMR4   A0A2U9K4C4   A0A0C9QT46   A0A1W4XNC8   Q16P80   E2AX16   A0A023EME7   A0A182H3T8   A0A0K8TUE4   A0A0K8TUF3   A0A1J1I2E5   A0A1Q3FUT1   A0A195FTC9   A0A2H1W020   A0A0N1PH59   A0A1Q3FSB3   M9VAC6   A0A1Q3FRY5   P46428-2   A0A182VJ04   A0A182XAY9   A0A182HX63   B0WFX0   A0A2P8ZI29   A0A182RRD5   A0A182W3P5  

PDB

3VUR     E-value=7.67232e-100,     Score=925

KEGG

692543    K04097 prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18] | (RefSeq) GSTs

PATHWAY

00480    Glutathione metabolism - Bombyx mori (domestic silkworm)
00590    Arachidonic acid metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016740   GO:0004364   GO:0016021   GO:0018342   GO:0008318   GO:0006749   GO:0005515   GO:0022857   GO:0006468   GO:0004930   GO:0006420   GO:0004812   GO:0006418   GO:0006334   GO:0003779  

Length:

204

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0194

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.03605

outside

1  -  204

 

 

Pi

16.075078

Theta

20.054097

Tajima's D

-1.297932

CLR

184.741085

CSRT

0.0840457977101145

Interpretation

Uncertain