Gene

KWMTBOMO01496

Pre Gene Modal

BGIBMGA009109

Annotation

PREDICTED:_cyclin-dependent_kinase-like_4_[Amyelois_transitella]

Location

Bomo_Chr3(-):12451991-12456609      View in EpiBrowser

Full name

Cyclin-dependent kinase-like 2      

Alternative Name

Serine/threonine-protein kinase KKIAMRE

Location in the cell

Cytoplasmic   Reliability : 3.162

CDS

ATGGATAAATACGAGCAGCTATCCGTGGTCGGCGAGGGTTCATACGGCGTGGTGCTGAAGTGCCGTCGCCGCGACACAGGTCAGCTGGTCGCCATCAAGAAGTTCCTTGAGACCGAAGACGATGCTGCGGTCAGGAAAATGGCATTACGAGAGATCCGCATGTTGAAAAAACTGCGTCACGATCATCTGGTGAATATGATTGAGGTGTTCCGCCGAAAGCGAAGGTTTTACCTGGTCTTCGAGTACTTGGATCACACGCTGCTGGACGAGCTTGAAGCTTCACAAGGAGGCCTCGGGGAGGACACAGCGAAGAAACACCTGTACCAATTGCTGAAGGGAATTGATTATTGCCATCAGAATTCCATAATACATCGCGACGTGAAACCGGAGAACGTACTAGTGTCAAACGCTGGTATCGTGAAGCTCTGTGACTTGGGATTCGCGAGAACTCTGGCCGCTCCCGGCGAGCCTTACACGGAGTACGTGGCGACGAGGTGGTACAGGGCTCCTGAATTATTGGTCGCAGAGCACAGATACGGTCCAGAGGTAGACGTTTGGGCACTGGGCTGTCTGTTCGCGGAGATGTTGACGGGAGACCCTCTGTTCCCTGGAGACTCCGACATAGATCAATTAGCCCTTATAATAAAGACTGTAGGTAAGAATGATAACGATTTTTGTCAAAACTATTCTTAG

Protein

MDKYEQLSVVGEGSYGVVLKCRRRDTGQLVAIKKFLETEDDAAVRKMALREIRMLKKLRHDHLVNMIEVFRRKRRFYLVFEYLDHTLLDELEASQGGLGEDTAKKHLYQLLKGIDYCHQNSIIHRDVKPENVLVSNAGIVKLCDLGFARTLAAPGEPYTEYVATRWYRAPELLVAEHRYGPEVDVWALGCLFAEMLTGDPLFPGDSDIDQLALIIKTVGKNDNDFCQNYS

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Similarity

Belongs to the protein kinase superfamily.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Kinase   Nucleotide-binding   Nucleus   Reference proteome   Transferase  

Feature

chain  Cyclin-dependent kinase-like 2

Uniprot

H9JHW1   A0A2A4JFS8   A0A2H1WI05   A0A194Q382   A0A194RMF6   A0A0L7K3J6   + More
E0VX43   A0A2J7QHD6   A0A0T6B6P3   A0A1B6F466   A0A2T7PZA6   A0A0C9QXV1   V3Z119   C3YL96   D6WUR9   A0A210QG94   A0A1B6CUL1   A0A1B0CGA5   A0A087ZS99   A0A154PJ02   N6TIQ5   A0A1W4WIU7   A0A1W4WIT0   R7V9J2   H2Y3W0   A0A1S3KAD9   A0A1S3K9U9   H2Y3V9   F6QWY8   H2Y3V8   A0A1S3K9U4   A0A1S3KAD1   K7IPP7   A0A1S3KA73   A0A2C9JQL2   A0A3M6TSX6   A0A2C9JQK3   A0A2C9JQL7   A0A067RD32   A0A183R9U1   A0A3Q0JZT4   A0A226ESS1   F2UEJ9   A0A183NDR2   W5N7J7   A0A336MND0   A0A1X7VQD3   A0A1Y1MW82   T1J364   A0A232EWX5   A0A1Y1MV14   E2AP61   W4XB17   A0A093Q324   A0A026WVE3   F4W3V9   A7SLJ0   A0A0M9A861   G4LZG2   A0A3M0L2P0   A0A1I8HR15   A0A1U7RIQ7   A0A091EVQ6   A0A3Q0KRY8   A0A2A3ENW8   V3ZQ35   A0A341C6C8   A0A0L8H3E8   K1R502   E1C431   K7FM36   A0A1D5P2Z1   A0A1S3N9Z4   A0A2U4B507   A0A087VB17   A0A1S3NAI7   H2ZSK2   V8NMC2   A0A3P8UCX8   A0A151WZF7   A0A2Y9F252   A0A218UPD9   A9UR26   G1KI16   A0A158P355   A0A091CS16   G1U2W5   Q9TTK0   G1SJC0   A0A091K6Z5   A0A091KMJ9   A0A3L8S4K2   A0A093I150   A0A2U4B4Z3   V9KJA9   A0A2K6MTD1   G3Q3W8   A0A087R8F5   A0A091CUR7   A0A091SWC4  

EC Number

2.7.11.22

Pubmed

19121390    26354079    26227816    20566863    23254933    18563158    + More
18362917    19820115    28812685    23537049    12481130    15114417    20075255    15562597    30382153    24845553    28004739    28648823    20798317    24508170    30249741    21719571    17615350    22253936    26392545    22992520    15592404    17381049    9215903    24297900    18273011    21347285    21993624    10531455    30282656    24402279   

EMBL

BABH01029583    NWSH01001616    PCG70679.1    ODYU01008793    SOQ52703.1    KQ459562    + More
KPI99803.1    KQ459989    KPJ18609.1    JTDY01011776    KOB52976.1    DS235829    EEB17949.1    NEVH01013976    PNF28008.1    LJIG01009466    KRT83023.1    GECZ01024717    JAS45052.1    PZQS01000001    PVD38752.1    GBYB01000525    JAG70292.1    KB203566    ESO84233.1    GG666526    EEN58966.1    KQ971363    EFA07808.2    NEDP02003775    OWF47770.1    GEDC01020122    JAS17176.1    AJWK01010914    KQ434931    KZC11783.1    APGK01036310    KB740939    KB631813    ENN77713.1    ERL86380.1    AMQN01004609    KB293927    ELU15229.1    EAAA01000896    RCHS01002978    RMX44495.1    KK852544    KDR21637.1    LNIX01000002    OXA60549.1    GL832971    EGD75049.1    UZAL01000191    VDO68829.1    AHAT01002063    UFQS01001832    UFQT01001832    SSX12479.1    SSX31922.1    GEZM01020121    JAV89388.1    JH431820    NNAY01001812    OXU22847.1    GEZM01020120    JAV89389.1    GL441452    EFN64797.1    AAGJ04019522    AAGJ04019523    AAGJ04019524    KL671645    KFW83036.1    KK107087    QOIP01000001    EZA59948.1    RLU27585.1    GL887486    EGI71113.1    EGI71114.1    DS469699    EDO35402.1    KQ435714    KOX79215.1    CABG01000060    CCD60280.1    QRBI01000105    RMC13577.1    KK719193    KFO61973.1    KZ288204    PBC33204.1    KB201891    ESO93498.1    KQ419417    KOF83599.1    JH817665    EKC38559.1    AADN05000017    AGCU01102015    AGCU01102016    KL486580    KFO09809.1    AFYH01213687    AFYH01213688    AZIM01002858    ETE63210.1    KQ982649    KYQ53081.1    MUZQ01000210    OWK55280.1    CH991544    EDQ92174.1    ADTU01007751    ADTU01007752    ADTU01007753    KN124661    KFO20633.1    AAGW02005992    AAGW02005993    AB029045    AAGW02022958    AAGW02022959    AAGW02022960    KK545048    KFP32086.1    KK746750    KFP40485.1    QUSF01000069    RLV96722.1    KL206972    KFV87651.1    JW865675    AFO98192.1    KL226208    KFM09759.1    KN123782    KFO23304.1    KK489141    KFQ62944.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000037510    UP000009046    + More
UP000235965    UP000245119    UP000030746    UP000001554    UP000007266    UP000242188    UP000092461    UP000005203    UP000076502    UP000019118    UP000030742    UP000192223    UP000014760    UP000007875    UP000085678    UP000008144    UP000002358    UP000076420    UP000275408    UP000027135    UP000050792    UP000198287    UP000007799    UP000050791    UP000018468    UP000007879    UP000215335    UP000000311    UP000007110    UP000053258    UP000053097    UP000279307    UP000007755    UP000001593    UP000053105    UP000008854    UP000269221    UP000095280    UP000189705    UP000052976    UP000242457    UP000252040    UP000053454    UP000005408    UP000000539    UP000007267    UP000087266    UP000245320    UP000008672    UP000265080    UP000075809    UP000248484    UP000197619    UP000001357    UP000001646    UP000005205    UP000028990    UP000001811    UP000276834    UP000053584    UP000233180    UP000007635    UP000053286   

PRIDE

H9JHW1   

Pfam

PF00069   Pkinase        + More
PF00215   OMPdecase
PF00156   Pribosyltran

Interpro

IPR017441   Protein_kinase_ATP_BS        + More
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR029057   PRTase-like       
IPR001754   OMPdeCOase_dom       
IPR000836   PRibTrfase_dom       
IPR011060   RibuloseP-bd_barrel       
IPR023031   OPRT       
IPR014732   OMPdecase       
IPR004467   Or_phspho_trans_dom       
IPR013785   Aldolase_TIM       

SUPFAM

SSF56112   SSF56112        + More
SSF53271   SSF53271       
SSF51366   SSF51366       

Gene 3D

3.20.20.70    

CDD

cd06223  PRTases_typeI

ProteinModelPortal

H9JHW1   A0A2A4JFS8   A0A2H1WI05   A0A194Q382   A0A194RMF6   A0A0L7K3J6   + More
E0VX43   A0A2J7QHD6   A0A0T6B6P3   A0A1B6F466   A0A2T7PZA6   A0A0C9QXV1   V3Z119   C3YL96   D6WUR9   A0A210QG94   A0A1B6CUL1   A0A1B0CGA5   A0A087ZS99   A0A154PJ02   N6TIQ5   A0A1W4WIU7   A0A1W4WIT0   R7V9J2   H2Y3W0   A0A1S3KAD9   A0A1S3K9U9   H2Y3V9   F6QWY8   H2Y3V8   A0A1S3K9U4   A0A1S3KAD1   K7IPP7   A0A1S3KA73   A0A2C9JQL2   A0A3M6TSX6   A0A2C9JQK3   A0A2C9JQL7   A0A067RD32   A0A183R9U1   A0A3Q0JZT4   A0A226ESS1   F2UEJ9   A0A183NDR2   W5N7J7   A0A336MND0   A0A1X7VQD3   A0A1Y1MW82   T1J364   A0A232EWX5   A0A1Y1MV14   E2AP61   W4XB17   A0A093Q324   A0A026WVE3   F4W3V9   A7SLJ0   A0A0M9A861   G4LZG2   A0A3M0L2P0   A0A1I8HR15   A0A1U7RIQ7   A0A091EVQ6   A0A3Q0KRY8   A0A2A3ENW8   V3ZQ35   A0A341C6C8   A0A0L8H3E8   K1R502   E1C431   K7FM36   A0A1D5P2Z1   A0A1S3N9Z4   A0A2U4B507   A0A087VB17   A0A1S3NAI7   H2ZSK2   V8NMC2   A0A3P8UCX8   A0A151WZF7   A0A2Y9F252   A0A218UPD9   A9UR26   G1KI16   A0A158P355   A0A091CS16   G1U2W5   Q9TTK0   G1SJC0   A0A091K6Z5   A0A091KMJ9   A0A3L8S4K2   A0A093I150   A0A2U4B4Z3   V9KJA9   A0A2K6MTD1   G3Q3W8   A0A087R8F5   A0A091CUR7   A0A091SWC4  

PDB

4BBM     E-value=1.61823e-84,     Score=794

KEGG

101741709    K08824 cyclin-dependent kinase-like [EC:2.7.11.22] | (RefSeq) cyclin-dependent kinase-like 4

GO

GO:0005524   GO:0004674   GO:0004672   GO:0004693   GO:0006468   GO:0005634   GO:0016301   GO:0004590   GO:0009116   GO:0006207   GO:0004588   GO:0044205   GO:0005813   GO:0005737   GO:0004930   GO:0006420   GO:0004812   GO:0006418   GO:0006334   GO:0003779   GO:0016021  

Subcellular location

Cytoplasm  
Nucleus  

Length:

230

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00814

Exp number, first 60 AAs:

0.00068

Total prob of N-in:

0.07869

outside

1  -  230

 

 

Pi

233.850909

Theta

193.375779

Tajima's D

0.696672

CLR

0.001827

CSRT

0.572571371431428

Interpretation

Uncertain