Gene

KWMTBOMO01490

Pre Gene Modal

BGIBMGA009050

Annotation

PREDICTED:_sarcoplasmic_calcium-binding_protein_1_[Bombyx_mori]

Location

Bomo_Chr3(+):12317410-12331974      View in EpiBrowser

Full name

Sarcoplasmic calcium-binding protein 1       + More
Sarcoplasmic calcium-binding protein      
Sarcoplasmic calcium-binding protein, alpha-B and -A chains      
Sarcoplasmic calcium-binding protein, beta chain      

Alternative Name

Sarcoplasmic calcium-binding protein I

Location in the cell

Cytoplasmic   Reliability : 2.57

CDS

ATGGCGTATTCGTGGGACAATCGTGTCGCTTTCGTTGTAAAATATCTTTACGATATAGACAACAATGGGTATCTAGATGCGCACGATTTCCATTGTCTGGCGCTCCGGACGTGCGTGCTTGAAGGGAAGGGCGACTGCAGCTCCGCCCGTCTCCAGAAGTACCAGCACGTGATGCTCAATCTGTGGGAGGAGATCGCACAGCTGGCGGACTTCGACAAGGTGCCGGACTATGACGGCATCGTAACGGTAGACGAGTTTAAGCAGGCTGTTATGAACAGCTGCGTGGGTAGGAGGTACGAAGACTTCCCCCAGTCGATGCGAGCGTTCATCGAGACTAACTTCAGAATGATCGACATTAACTGTGACGGTGTGCTCGCCCTCGAAGAGTATAGATACGACTGCGTGCAGAGGATGGTCGTGGAGGATATCAAGGTTGTCGACGAAGCCTACAGTACACTGTTAAATGATGACGACAGGCGGAGGGGCGGCCTGACGCTCTCCAGATATCAAGAACTCTTCGCTCAGTTCCTGGGCGACGTTAGCGATGACTGCGAAGCGAAACACTTGTTTGGACCATTAGAATTTTAG

Protein

MAYSWDNRVAFVVKYLYDIDNNGYLDAHDFHCLALRTCVLEGKGDCSSARLQKYQHVMLNLWEEIAQLADFDKVPDYDGIVTVDEFKQAVMNSCVGRRYEDFPQSMRAFIETNFRMIDINCDGVLALEEYRYDCVQRMVVEDIKVVDEAYSTLLNDDDRRRGGLTLSRYQELFAQFLGDVSDDCEAKHLFGPLEF

Description

Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.

Biophysicochemical Properties

Relatively stable at broad pH range (pH 1-11). Dimers are formed in strongly acidic (pH 2-5) and alkaline (pH 10-11) conditions.

Subunit

SCPs from crayfish, lobster, and shrimp are polymorphic dimers.
Monomer and dimer.
SCPs from crayfish, lobster, and shrimp are polymorphic dimers; three isotypes (alpha-alpha, alpha-beta, and beta-beta) have been identified.

Miscellaneous

The sarcoplasmic calcium-binding proteins are abundant in the muscle of arthropods, mollusks, annelids, and protochordates.
This protein has three functional calcium-binding sites; potential site 4 has lost affinity for calcium.

Keywords

Acetylation   Calcium   Direct protein sequencing   Metal-binding   Muscle protein   Repeat   Allergen  

Feature

chain  Sarcoplasmic calcium-binding protein 1

Uniprot

A0A2H1WEM3   A0A2A4J2S6   A0A194RLA4   H9JHQ2   A0A0L7LP94   A0A1E1WKC2   + More
A0A212ETI3   A0A194Q2L9   D2CFZ9   E9J1S4   A0A1W4X813   A0A1W4X9A6   A0A1Y1M1M1   A0A1Y1LXD3   A0A0A1WYS5   A0A026WWM5   A0A034W0J5   A0A195BL11   N6U896   W8C4J5   A0A087ZW81   A0A2A3ELA8   J3JXE7   B4ISL9   B3N4M8   B3MX55   B4JPM2   Q8MSI2   A0A0Q9WAI6   A0A0L0CM05   A0A1I8NHR0   K7J2V3   A0A1L8DCR8   A0A1L8DD11   A0A084WHB5   Q6XHW1   A0A182IQ66   O16157   A0A1I8QBG0   A0A2M4AYX4   T1DNU3   A0A1Q3FNT8   A0A182Q3T1   A0A2M4CSX0   T1E2F6   A0A1A9WHF8   A0A1Q3FNY8   T1D4Z1   A0A182UPK7   A0A182L201   Q7Q3N6   A0A1A9UD15   A0A1B0AH80   D3TN50   B0W2W0   E2C5L4   A0A1J1I2G3   A0A3B0JU06   A0A0M9A8C2   U5EL01   A0A023EJ67   A0A0M3QT56   E2AJ60   Q16XK7   A0A3L8DB46   A0A158NJ75   A0A151JVA5   A0A1B0CML7   H7CHW3   A0A336MI81   A0A151WE76   H7CHW2   C7A639   E7CGC4   C1BRV4   F6M209   F6M210   C1BUL8   D3PG38   F6M208   A0A0B5JJZ2   Q2XT28   A0A182XZU1   P05946   I2DDG2   C1BN93   A0A0B5JEF0   C1BQ76   A0A0B5JGW7   P02636   A0A2R5LJU2   A0A0K2U4J0   A0A1B0C3R5   A0A0L7QVK6   A0A154PRC1   D7F1P9   A0A0J7L5V5   P02635   A0A0Q9WHQ6   A0A151JNI0  

Pubmed

26354079    19121390    26227816    22118469    18362917    19820115    + More
21282665    28004739    25830018    24508170    25348373    23537049    24495485    22516182    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    26108605    25315136    20075255    24438588    14525923    9443378    24330624    20966253    12364791    14747013    17210077    20353571    20798317    24945155    17510324    30249741    21347285    23180551    19523674    21530674    16807031    25244985    2917647    28692255    30187588    6469940    6490607   

EMBL

ODYU01007827    SOQ50924.1    NWSH01003404    PCG66365.1    KQ459989    KPJ18613.1    + More
BABH01029593    JTDY01000425    KOB77245.1    GDQN01003697    JAT87357.1    AGBW02012571    OWR44803.1    KQ459562    KPI99807.1    DS497677    EFA11861.1    GL767674    EFZ13251.1    GEZM01044429    JAV78225.1    GEZM01044430    JAV78224.1    GBXI01010300    GBXI01009173    JAD03992.1    JAD05119.1    KK107078    EZA60462.1    GAKP01011105    GAKP01011104    JAC47847.1    KQ976453    KYM85400.1    APGK01035636    APGK01035637    KB740928    KB632064    ENN77890.1    ERL88464.1    GAMC01002272    JAC04284.1    KZ288215    PBC32490.1    BT127916    AEE62878.1    CH891577    EDW99374.1    CH954177    EDV59982.1    CH902628    EDV34911.2    CH916372    EDV98852.1    AY118788    AE013599    AAM50648.1    EAA46049.1    ELP57405.1    CH940649    KRF81720.1    KRF81721.1    KRF81722.1    JRES01000200    KNC33335.1    GFDF01009826    JAV04258.1    GFDF01009827    JAV04257.1    ATLV01023800    KE525346    KFB49609.1    AY232072    AAR10095.1    AF014951    AAB67804.1    GGFK01012649    MBW45970.1    GAMD01002575    JAA99015.1    GFDL01005851    JAV29194.1    AXCN02000699    GGFL01004268    MBW68446.1    GALA01000764    JAA94088.1    GFDL01005852    JAV29193.1    GALA01000763    JAA94089.1    AAAB01008964    EAA12855.3    CCAG010005466    EZ422852    ADD19128.1    DS231829    EDS30319.1    GL452770    EFN76827.1    CVRI01000038    CRK93954.1    OUUW01000010    SPP85597.1    KQ435713    KOX79310.1    GANO01001637    JAB58234.1    GAPW01004729    JAC08869.1    CP012523    ALC38299.1    GL439967    EFN66500.1    CH477537    EAT39351.1    QOIP01000011    RLU17138.1    ADTU01017549    KQ981703    KYN37447.1    AJWK01018890    AJWK01018891    AJWK01018892    AJWK01018893    AJWK01018894    AJWK01018895    AB703462    BAL72726.1    UFQS01001258    UFQT01001258    SSX10003.1    SSX29725.1    KQ983247    KYQ46169.1    AB703461    BAL72725.1    FJ184279    ACM89179.1    HM034315    ADV17343.1    BT077333    BT078404    ACO11757.1    JF692203    AEG79568.1    JF692204    AEG79569.1    BT078297    ACO12721.1    BT120594    ADD24234.1    JF692202    AEG79567.1    KM244728    AJG01361.1    DQ256199    ABB58783.1    JQ860424    AFJ80778.1    BT076072    ACO10496.1    KM244726    AJG01359.1    BT076755    ACO11179.1    KM244727    AJG01360.1    GGLE01005569    MBY09695.1    HACA01015579    CDW32940.1    JXJN01025090    KQ414727    KOC62541.1    KQ435078    KZC14442.1    FJ462737    ACR43475.1    LBMM01000596    KMQ97996.1    KRF81719.1    KQ978858    KYN27921.1   

Proteomes

UP000218220    UP000053240    UP000005204    UP000037510    UP000007151    UP000053268    + More
UP000007266    UP000192223    UP000053097    UP000078540    UP000019118    UP000030742    UP000005203    UP000242457    UP000002282    UP000008711    UP000007801    UP000001070    UP000000803    UP000008792    UP000037069    UP000095301    UP000002358    UP000030765    UP000075880    UP000095300    UP000075886    UP000091820    UP000075903    UP000075882    UP000007062    UP000078200    UP000092445    UP000092444    UP000002320    UP000008237    UP000183832    UP000268350    UP000053105    UP000092553    UP000000311    UP000008820    UP000279307    UP000005205    UP000078541    UP000092461    UP000075809    UP000076408    UP000092460    UP000053825    UP000076502    UP000036403    UP000078492   

PRIDE

H9JHQ2    Q8MSI2    O16157    P02636   

Pfam

PF13202   EF-hand_5        + More
PF13833   EF-hand_8
PF13499   EF-hand_7
PF00036   EF-hand_1
PF07525   SOCS_box
PF00622   SPRY

Interpro

IPR002048   EF_hand_dom        + More
IPR011992   EF-hand-dom_pair       
IPR018247   EF_Hand_1_Ca_BS       
IPR001496   SOCS_box       
IPR003877   SPRY_dom       
IPR013320   ConA-like_dom_sf       
IPR001870   B30.2/SPRY       

SUPFAM

SSF47473   SSF47473        + More
SSF49899   SSF49899       

CDD

cd00051  EFh

ProteinModelPortal

A0A2H1WEM3   A0A2A4J2S6   A0A194RLA4   H9JHQ2   A0A0L7LP94   A0A1E1WKC2   + More
A0A212ETI3   A0A194Q2L9   D2CFZ9   E9J1S4   A0A1W4X813   A0A1W4X9A6   A0A1Y1M1M1   A0A1Y1LXD3   A0A0A1WYS5   A0A026WWM5   A0A034W0J5   A0A195BL11   N6U896   W8C4J5   A0A087ZW81   A0A2A3ELA8   J3JXE7   B4ISL9   B3N4M8   B3MX55   B4JPM2   Q8MSI2   A0A0Q9WAI6   A0A0L0CM05   A0A1I8NHR0   K7J2V3   A0A1L8DCR8   A0A1L8DD11   A0A084WHB5   Q6XHW1   A0A182IQ66   O16157   A0A1I8QBG0   A0A2M4AYX4   T1DNU3   A0A1Q3FNT8   A0A182Q3T1   A0A2M4CSX0   T1E2F6   A0A1A9WHF8   A0A1Q3FNY8   T1D4Z1   A0A182UPK7   A0A182L201   Q7Q3N6   A0A1A9UD15   A0A1B0AH80   D3TN50   B0W2W0   E2C5L4   A0A1J1I2G3   A0A3B0JU06   A0A0M9A8C2   U5EL01   A0A023EJ67   A0A0M3QT56   E2AJ60   Q16XK7   A0A3L8DB46   A0A158NJ75   A0A151JVA5   A0A1B0CML7   H7CHW3   A0A336MI81   A0A151WE76   H7CHW2   C7A639   E7CGC4   C1BRV4   F6M209   F6M210   C1BUL8   D3PG38   F6M208   A0A0B5JJZ2   Q2XT28   A0A182XZU1   P05946   I2DDG2   C1BN93   A0A0B5JEF0   C1BQ76   A0A0B5JGW7   P02636   A0A2R5LJU2   A0A0K2U4J0   A0A1B0C3R5   A0A0L7QVK6   A0A154PRC1   D7F1P9   A0A0J7L5V5   P02635   A0A0Q9WHQ6   A0A151JNI0  

PDB

2SAS     E-value=0.000454129,     Score=99

KEGG

101747070    no KO assigned | (RefSeq) sarcoplasmic calcium-binding protein 1

GO

GO:0005509  

Length:

195

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00024

Exp number, first 60 AAs:

0.00024

Total prob of N-in:

0.24000

outside

1  -  195

 

 

Pi

191.058689

Theta

160.827402

Tajima's D

0.518039

CLR

0.399375

CSRT

0.51972401379931

Interpretation

Uncertain