SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01488  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA009049
Annotation
PREDICTED:_Niemann-Pick_C1_protein_[Bombyx_mori]
Location in the cell
PlasmaMembrane   Reliability : 4.343
 

Sequence

CDS
ATGGCCTGCGCCGTCGATCAGAGCAAATACTTGAAGCCAGTTCAAACAGAACAGTTCAACGGTACACATCGCAGGATATCTGAGATCGATTACTACCTGAGTAAAACTTTCATGGATGGCATCTACAACTCATGCTCTGAGGTTAAGCTTACGTCAACAAACGAGCGATCCATAAAGGTGATGTGCGGTCAGTGGGGAGACGCGTGCTCGGCGCAACGTTGGTTCGATAACATGGGGGACGCTTCCAACTATCAAGTGCCCTTCCAGATTAACTATAAGGCCACTGACGTGCCCGTCGATGGGTACACGCCCTACGCTCCGATAGCCGAGCCCTGCAATGTCGGAACGAAGGGCATGCCGGGCTGCTCGTGCCTGGACTGCGAGGCGTCGTGCCCCGCGCCCCCGCCGCGCCCCCCGCCCCCGCAGCCGTTCTCCATCGCGGGCTTCGACGGCTACGCAATCGTCATGACCATCGTATTCTGTATCTTCTCGACGCTGTTCCTCACGGGCGTCTTCTGTTGCAATCAAACCGAAAACCTCGTTGAGTGCGGCCCCGAGACGAGCCCGCTGCACGAGCGCCGCGCCAGTACGTACCCGCCCCTACTGCATACGCACGGTGTGTCTTCAGACAACAATCAAGAGATGGGAACAAACGCGTCGGGCACGCGCTGGACCATGGAGGCCACCGATGGCGACGAGACAGACGCGACGTTCCTCGAGAAGCTCGGTGCTGCGACGGAATCCAAAATTGAAGACTTCTTCCAGTGGTGGGGCTGCGTCATGGCCTCCTCGCCTTGGCTGGTCCTCTTCTCTGGTTTGTGCGTTGTGGTGATCCTCGGCTCCGGCATCACGTACATGCAGGTGACCACCGACCCCGTGGAGCTGTGGGCCTCGCCCACCTCGCGCTCCAGGGTCGAGAGGCAGCGGTTCGATTCCTACTTCGAACCTTTCTACAGGACAGAAATGTTAATAATCAGCTCGAAAGGTCTGCCCGAGATCGAACACGCGAACCTGACTTTCGGGCCTGTGTTCAACGCCACCTTCATGCTGGACGTGTTCGACCTGCAGTCCAAGATCTTAGAGCTCGGCAACGAGTCCGGGATCCAGAACATTTGCTACGCGCCGCTGTCGTCGCCCTTCCGCGGCCCCGTCACCAGCAAGGACTGCGTGCTGCAGAGCGTGTGGGGCTGGTGGCAGAACGACAAGTCCGAGTTCTCCTACGAGGACAACGAACACCTGGACAAGATCCTGCAGTGCTCCAGCAACCCGATCTCGGTGGACTGCCTGTCGTCGTACGGCGGGCCCGTCCTGCCCGGCGTGGCGCTGGGCGGCTTCCTGCCGCGCGGCGACCAGCTCTCTGCCCACGCGCCCTACCACCGCGCGCAGGCACTCATCCTCACCTTTCTCGTCAACAACAAGCAGGACAAGTCCCAGCTGAAACAAGCACTGGAGTGGGAGAAGACGTTCATTGCGTTCATGAAGAACTACACGGAGAAGGCGATGCCGGGCTACATGGACATCGCGTACACGTCGGAGCGCTCCATCGAGGACGAGCTGGACCGCGAGTCCAAGTCGGACGTGTACACCATCCTCGTGTCCTACTTCATCATGTTCGCGTACATCGCCATCGCGCTCGGCCGCTTCACCACCTTCTCGCGGCTGCTCATCGACAGCAAGATCACGCTCGGGCTCGGCGGTGTGGTTATCGTGTTGGCGTCTGTGGTGTGCTCCATGGGCATCTTCGGGTTCTATGGAGTGGCGGCCACGCTTATCATCGTGGAGGTCATCCCGTTCCTGGTGCTGGCCGTCGGCGTCGACAACATCTTCATCCTGGTGCAGACCCACCAGCGCGAGCCGCGCCGCCCCGACGAGACCGTCGAGCAACACATCGGTAGAATGCTCGGCAAGGTGGGCCCGTCGATGTTCGTGACGTCGGTGTCGGAGTCGGTGTGCTTCTTCCTGGGGGCGCTGAGCGACATGCCGGCCGTGCGCGCCTTCGCGCTGTACGCCGCCGTGGCGCTGCTCGTGGACTTCCTGCTGCAGGTCACCTGCTTCGTGGCGCTGCTGGCGCTGGACACGCGCCGACAACTCGACAACAGGTGA
Protein
MACAVDQSKYLKPVQTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFQINYKATDVPVDGYTPYAPIAEPCNVGTKGMPGCSCLDCEASCPAPPPRPPPPQPFSIAGFDGYAIVMTIVFCIFSTLFLTGVFCCNQTENLVECGPETSPLHERRASTYPPLLHTHGVSSDNNQEMGTNASGTRWTMEATDGDETDATFLEKLGAATESKIEDFFQWWGCVMASSPWLVLFSGLCVVVILGSGITYMQVTTDPVELWASPTSRSRVERQRFDSYFEPFYRTEMLIISSKGLPEIEHANLTFGPVFNATFMLDVFDLQSKILELGNESGIQNICYAPLSSPFRGPVTSKDCVLQSVWGWWQNDKSEFSYEDNEHLDKILQCSSNPISVDCLSSYGGPVLPGVALGGFLPRGDQLSAHAPYHRAQALILTFLVNNKQDKSQLKQALEWEKTFIAFMKNYTEKAMPGYMDIAYTSERSIEDELDRESKSDVYTILVSYFIMFAYIAIALGRFTTFSRLLIDSKITLGLGGVVIVLASVVCSMGIFGFYGVAATLIIVEVIPFLVLAVGVDNIFILVQTHQREPRRPDETVEQHIGRMLGKVGPSMFVTSVSESVCFFLGALSDMPAVRAFALYAAVALLVDFLLQVTCFVALLALDTRRQLDNR

Summary

EMBL
BABH01029600    BABH01029601    BABH01029602    GDQN01005456    JAT85598.1    GDQN01010904    + More
GDQN01009686    JAT80150.1    JAT81368.1    NWSH01001793    PCG70124.1    AGBW02012571    OWR44805.1    PCG70125.1    KQ459562    KPI99808.1    ODYU01007827    SOQ50927.1    KQ435078    KZC14443.1    GAIX01013884    JAA78676.1    KQ414727    KOC62540.1    KK852428    KDR24042.1    KQ971357    KYB26045.1    EFA11848.2    KQ978411    KYM94111.1    GFDF01002747    JAV11337.1    NNAY01000911    OXU25955.1    GFDF01007339    JAV06745.1    GFDF01007330    JAV06754.1    GFDF01007331    JAV06753.1    GL452770    EFN76828.1    KQ981703    KYN37448.1    KK107078    QOIP01000011    EZA60461.1    RLU17131.1    ADTU01017546    ADTU01017547    ADTU01017548    ADTU01017549    KQ976453    KYM85401.1    GEZM01102125    JAV51949.1    GANO01000231    JAB59640.1    GEZM01102127    JAV51947.1    AJWK01018887    AJWK01018888    AJWK01018889    AJWK01018890    KQ983247    KYQ46170.1    KQ435713    KOX79311.1    JR037261    AEY57665.1    GEZM01102128    JAV51946.1    KZ288215    PBC32491.1    JR037260    AEY57664.1    KQ978858    KYN27920.1    GEZM01102126    JAV51948.1    GL439967    EFN66499.1    JXUM01017416    JXUM01017417    JXUM01017418    KQ560483    KXJ82189.1    KB632196    ERL89983.1    CVRI01000055    CRL00931.1    GAMC01019805    GAMC01019804    GAMC01019803    JAB86751.1    GFDL01009411    JAV25634.1    GFDL01009355    JAV25690.1    GFDL01009318    JAV25727.1    GFDL01009138    JAV25907.1    GAMC01019808    GAMC01019807    GAMC01019806    JAB86748.1    GBYB01002583    JAG72350.1    DS231890    EDS43825.1    KK854561    PTY16899.1    GL888206    EGI65127.1    GFDL01010521    JAV24524.1    GFDL01010528    JAV24517.1    GGFK01000622    MBW33943.1    GBXI01016090    GBXI01000437    JAC98201.1    JAD13855.1    CCAG010014196    GBGD01000124    JAC88765.1    GFTR01008772    JAW07654.1    GBXI01015530    JAC98761.1    ACPB03008313    ACPB03008314    GGFK01001580    MBW34901.1    GAKP01020483    GAKP01020482    JAC38469.1    GGFJ01000541    MBW49682.1    GGFJ01000573    MBW49714.1    CH916372    EDV98847.1    CH902620    EDV32276.1    KPU73872.1    KPU73873.1    KPU73874.1    KPU73875.1    ADMH02002111    ETN58868.1    AXCM01006422    GGFM01000497    MBW21248.1    GAKP01020485    GAKP01020484    JAC38467.1    KPU73871.1    GDHF01020819    GDHF01017640    JAI31495.1    JAI34674.1    GDHF01012848    GDHF01001051    JAI39466.1    JAI51263.1    CH480818    EDW52369.1    AE014134    AAF52874.2    ADV37019.1    ADV37020.1    ADV37021.1    OUUW01000006    SPP81585.1    APCN01002466    CH933807    EDW13556.2    GEDC01025665    JAS11633.1    AJ249606    CAB56505.1   
Pfam
PF12349   Sterol-sensing        + More
PF16414   NPC1_N
PF02460   Patched
PF03129   HGTP_anticodon
PF00076   RRM_1
PF00160   Pro_isomerase
Interpro
IPR000731   SSD        + More
IPR003392   Ptc/Disp       
IPR032190   NPC1_N       
IPR004765   NPC1-like       
IPR036621   Anticodon-bd_dom_sf       
IPR004154   Anticodon-bd       
IPR020846   MFS_dom       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR029000   Cyclophilin-like_dom_sf       
IPR035538   Cyclophilin_PPIL4       
IPR035979   RBD_domain_sf       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
SUPFAM
SSF50891   SSF50891        + More
SSF54928   SSF54928       
Gene 3D
PDB
5JNX     E-value=2.76541e-120,     Score=1108

Ontologies

Topology

Length:
700
Number of predicted TMHs:
7
Exp number of AAs in TMHs:
154.41814
Exp number, first 60 AAs:
0.00044
Total prob of N-in:
0.06461
outside
1  -  151
TMhelix
152  -  174
inside
175  -  265
TMhelix
266  -  288
outside
289  -  526
TMhelix
527  -  549
inside
550  -  561
TMhelix
562  -  584
outside
585  -  588
TMhelix
589  -  611
inside
612  -  637
TMhelix
638  -  657
outside
658  -  666
TMhelix
667  -  689
inside
690  -  700
 
 

Population Genetic Test Statistics

Pi
259.30678
Theta
18.779667
Tajima's D
1.274065
CLR
0.268194
CSRT
0.741162941852907
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
28467696 ATDQTFVEK 100.00 1e-11
28467696 WFAEDGQITK 100.00 2e-09
26822097 GGYSCCNYEQINQIK 100.00 1e-04
26280517 VKTIHPAVHAGIIAR 100.00 1e-04
28467696 VMAPFTPFITEFMYK 100.00 1e-04
26822097 FDIFCCIR 100.00 0.001
28467696 AMNSNWHPACFR 100.00 0.001
26280517 QQYWPIQNSNIQK 100.00 0.045
28467696 QRDGVTTITYR 100.00 0.045
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