Gene

KWMTBOMO01478  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009043

Annotation

Glyoxylate_reductase/hydroxypyruvate_reductase_[Operophtera_brumata]

Location

Bomo_Chr3(+):12095010-12099366      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.768

CDS

ATGTTTTTTTTATACTCTTCTAGGGGAGAATGGGAGATCGGCTTCGACAAGGTCCTAGGGCAAGACCTCCGCGACAGCACCGTAGGGATCATCGGCTTGGGTGGTATTGGACAGGCTGTCGTCAAACGTCTTAGTGGTTTTGATGTCGCCAGGTTTATTTACTCCGGACACAGAGAAAAACCCGAAGCTAAAGCCCTTAGAGCAGAGTTCGTAAGTCAGGACACGTTGCTGGAGCAAAGTGACTTCATCGTCGCGGCCGTGCCTCTGACTAATGAGACCAAGTTGATGATCAACAAAGAGACGCTGGGGAAAATGAAACCGAACGCTGTGTTCGTTAATGTAGGACGCGGAGACCTCGTTGACCAAGACGCTTTGTATGACGCATTGAAGAACAAACAGATCTACGCGGCTGGACTGGACGTGACTACGCCCGAACCGCTGCCCAAGGACCACAAGCTCTTAACGCTGCCGAACTTATTTGTACTCCCGCATATCGGTAGCGCGACGGTGCGGACCCGCCGAGAGATGGCAGAGTTGGCAGCCAATAATATTGTCAACGGCCTCACTGGCAAACCTTTGCTGTCACCTGTCAAACTATAA

Protein

MFFLYSSRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKALRAEFVSQDTLLEQSDFIVAAVPLTNETKLMINKETLGKMKPNAVFVNVGRGDLVDQDALYDALKNKQIYAAGLDVTTPEPLPKDHKLLTLPNLFVLPHIGSATVRTRREMAELAANNIVNGLTGKPLLSPVKL

Similarity

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Uniprot

H9JHP5   A0A2H1WT70   A0A0L7KWI0   S4PFM5   A0A212FBI2   A0A0K8SB31   + More
A0A2A4K050   A0A194Q2P9   A0A194RRF7   A0A154PEX2   A0A240PNC1   A0A0K8TTH6   A0A0L7R9W9   A0A0J7KVE5   A0A194RM74   S4NNY5   A0A088ACZ2   A0A310S8D9   A0A2A3ECR6   A0A0N0BF68   A0A1L8E2R3   E2BAZ5   A0A2H1WSZ4   A0A195EZN3   A0A1Y1KXC6   A0A026WDB2   A0A194Q2N4   A0A195DFG0   E2AAM6   A0A158P2R5   A0A1Q3FF49   A0A2A4JZ34   Q7PLZ4   A0A182L600   E2AAM7   A0A084VNK2   A0A182MG47   A0A1J1IR82   A0A182JHA7   A0A182TZI0   A0A182Y8E9   N6TMT1   J3JWS9   A0A1W4W4J5   A0A182VTS2   B0X7N8   A0A1B6CDU5   W5JFL6   K7IRU7   A0A182QDU9   A0A1L8E316   F6YQH0   B4G728   A0A0P6JG77   A0A2K6EUM0   U4U406   A0A1S3JEW2   D6WXF3   A0A1S3ID78   A0A182XCG6   A0A2K5D7T9   A0A182ICN6   A0A0R3NT36   A0A1B6DFZ9   A0A3B0K3J3   A0A0R3NT84   Q29LX7   A0A2M4BUL7   A0A3B0K0W2   A0A3B0JVU1   G3WTH0   A0A091V277   A0A2K5PZM3   A0A0Q9WXZ6   A0A232FHE6   A0A2K6TU49   H0VLZ2   A0A2C9JE82   U3D1B0   G1SS85   A0A2K5HMD3   A0A2Y9JA13   A0A2Y9T213   A0A2K5ZXA9   A0A2K5MK33   A0A2Y9J6D9   A0A2K5V7S5   A0A0A1XP69   A0A182NB20   B4MV55   I0FWH8   A0A0A1X9B8   H9G201   A0A2K5V7Q6   A0A0D9REF5   A0A023ENN7   A0A2K6DGY2   A0A096P151   A0A1B6EDW6   I3ME91  

Pubmed

19121390    26227816    23622113    22118469    26354079    26369729    + More
20798317    28004739    24508170    30249741    21347285    12364791    14747013    17210077    20966253    24438588    25244985    23537049    22516182    20920257    23761445    20075255    19892987    17994087    18362917    19820115    15632085    21709235    28648823    21993624    15562597    25243066    25830018    25319552    17431167    24945155    26483478   

EMBL

BABH01029615    ODYU01010836    SOQ56182.1    JTDY01005013    KOB67475.1    GAIX01003957    + More
JAA88603.1    AGBW02009318    OWR51095.1    GBRD01015348    JAG50478.1    NWSH01000342    PCG77274.1    KQ459562    KPI99821.1    KQ459989    KPJ18626.1    KQ434889    KZC10382.1    GDAI01000145    JAI17458.1    KQ414620    KOC67667.1    LBMM01002888    KMQ94234.1    KPJ18627.1    GAIX01012084    JAA80476.1    KQ764772    OAD54394.1    KZ288285    PBC29490.1    KQ435811    KOX72911.1    GFDF01001165    JAV12919.1    GL446901    EFN87086.1    SOQ56181.1    KQ981905    KYN33334.1    GEZM01075011    JAV64345.1    KK107260    QOIP01000001    EZA54065.1    RLU26898.1    KPI99822.1    KQ980903    KYN11596.1    GL438137    EFN69476.1    ADTU01007401    GFDL01008884    JAV26161.1    PCG77275.1    AAAB01008980    EAA14602.5    EFN69477.1    ATLV01014759    KE524984    KFB39546.1    AXCM01003646    CVRI01000055    CRL01017.1    APGK01058607    KB741291    KB632343    ENN70525.1    ERL93023.1    BT127697    AEE62659.1    DS232456    EDS42050.1    GEDC01025753    JAS11545.1    ADMH02001646    ETN61604.1    AXCN02000647    GFDF01001199    JAV12885.1    CH479180    EDW29227.1    GEBF01000924    JAO02709.1    KB631617    ERL84710.1    KQ971361    EFA08834.1    APCN01005735    CH379060    KRT04328.1    GEDC01012680    JAS24618.1    OUUW01000004    SPP79601.1    KRT04327.1    EAL33917.2    GGFJ01007500    MBW56641.1    SPP79599.1    SPP79600.1    AEFK01074518    AEFK01074519    KL410489    KFQ96824.1    CH963857    KRF98446.1    NNAY01000187    OXU30171.1    AAKN02030460    GAMT01008106    GAMS01010933    GAMR01004084    GAMQ01007050    GAMP01002453    JAB03755.1    JAB12203.1    JAB29848.1    JAB34801.1    JAB50302.1    AAGW02033558    AQIA01024138    GBXI01001959    JAD12333.1    EDW76400.2    JV048733    AFI38804.1    GBXI01006560    JAD07732.1    JSUE03014735    JU337157    JU477885    JV048732    AFE80910.1    AFH34689.1    AFI38803.1    AQIB01022110    JXUM01042370    GAPW01002561    KQ561321    JAC11037.1    KXJ78988.1    AHZZ02008496    GEDC01027514    GEDC01016543    GEDC01014322    GEDC01001170    JAS09784.1    JAS20755.1    JAS22976.1    JAS36128.1    AGTP01043657   

Proteomes

UP000005204    UP000037510    UP000007151    UP000218220    UP000053268    UP000053240    + More
UP000076502    UP000075885    UP000053825    UP000036403    UP000005203    UP000242457    UP000053105    UP000008237    UP000078541    UP000053097    UP000279307    UP000078492    UP000000311    UP000005205    UP000007062    UP000075882    UP000030765    UP000075883    UP000183832    UP000075880    UP000075902    UP000076408    UP000019118    UP000030742    UP000192223    UP000075920    UP000002320    UP000000673    UP000002358    UP000075886    UP000002281    UP000008744    UP000233160    UP000085678    UP000007266    UP000076407    UP000233020    UP000075840    UP000001819    UP000268350    UP000007648    UP000053283    UP000233040    UP000007798    UP000215335    UP000233220    UP000005447    UP000076420    UP000001811    UP000233080    UP000248482    UP000233140    UP000233060    UP000233100    UP000075884    UP000006718    UP000029965    UP000069940    UP000249989    UP000233120    UP000028761    UP000005215   

PRIDE

H9JHP5   

Pfam

PF00389   2-Hacid_dh        + More
PF02826   2-Hacid_dh_C
PF00856   SET
PF01753   zf-MYND
PF00651   BTB

Interpro

IPR029753   D-isomer_DH_CS        + More
IPR006140   D-isomer_DH_NAD-bd       
IPR006139   D-isomer_2_OHA_DH_cat_dom       
IPR036291   NAD(P)-bd_dom_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR002893   Znf_MYND       
IPR001214   SET_dom       
IPR011333   SKP1/BTB/POZ_sf       
IPR000210   BTB/POZ_dom       

SUPFAM

SSF51735   SSF51735        + More
SSF48452   SSF48452       
SSF54695   SSF54695       

Gene 3D

1.25.40.10    

ProteinModelPortal

H9JHP5   A0A2H1WT70   A0A0L7KWI0   S4PFM5   A0A212FBI2   A0A0K8SB31   + More
A0A2A4K050   A0A194Q2P9   A0A194RRF7   A0A154PEX2   A0A240PNC1   A0A0K8TTH6   A0A0L7R9W9   A0A0J7KVE5   A0A194RM74   S4NNY5   A0A088ACZ2   A0A310S8D9   A0A2A3ECR6   A0A0N0BF68   A0A1L8E2R3   E2BAZ5   A0A2H1WSZ4   A0A195EZN3   A0A1Y1KXC6   A0A026WDB2   A0A194Q2N4   A0A195DFG0   E2AAM6   A0A158P2R5   A0A1Q3FF49   A0A2A4JZ34   Q7PLZ4   A0A182L600   E2AAM7   A0A084VNK2   A0A182MG47   A0A1J1IR82   A0A182JHA7   A0A182TZI0   A0A182Y8E9   N6TMT1   J3JWS9   A0A1W4W4J5   A0A182VTS2   B0X7N8   A0A1B6CDU5   W5JFL6   K7IRU7   A0A182QDU9   A0A1L8E316   F6YQH0   B4G728   A0A0P6JG77   A0A2K6EUM0   U4U406   A0A1S3JEW2   D6WXF3   A0A1S3ID78   A0A182XCG6   A0A2K5D7T9   A0A182ICN6   A0A0R3NT36   A0A1B6DFZ9   A0A3B0K3J3   A0A0R3NT84   Q29LX7   A0A2M4BUL7   A0A3B0K0W2   A0A3B0JVU1   G3WTH0   A0A091V277   A0A2K5PZM3   A0A0Q9WXZ6   A0A232FHE6   A0A2K6TU49   H0VLZ2   A0A2C9JE82   U3D1B0   G1SS85   A0A2K5HMD3   A0A2Y9JA13   A0A2Y9T213   A0A2K5ZXA9   A0A2K5MK33   A0A2Y9J6D9   A0A2K5V7S5   A0A0A1XP69   A0A182NB20   B4MV55   I0FWH8   A0A0A1X9B8   H9G201   A0A2K5V7Q6   A0A0D9REF5   A0A023ENN7   A0A2K6DGY2   A0A096P151   A0A1B6EDW6   I3ME91  

PDB

2WWR     E-value=3.13192e-51,     Score=506

KEGG

101744216    K00049 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] | (RefSeq) glyoxylate reductase/h

PATHWAY

00260    Glycine, serine and threonine metabolism - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0051287   GO:0016616   GO:0055114   GO:0030267   GO:0016618   GO:0008465   GO:0005829   GO:0005737   GO:0046487   GO:0051259   GO:0070402   GO:0007588   GO:0042803   GO:0004930   GO:0006420   GO:0004812   GO:0006418   GO:0006334   GO:0003779   GO:0016021  

Length:

199

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0841100000000001

Exp number, first 60 AAs:

0.07331

Total prob of N-in:

0.02160

outside

1  -  199

 

 

Pi

290.319489

Theta

158.713487

Tajima's D

2.404469

CLR

0.176328

CSRT

0.936653167341633

Interpretation

Uncertain