Gene

KWMTBOMO01475

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr3(+):11960077-11963116      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.69

CDS

ATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCTCTGCACGTTGTTCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTCCTGAGCAGTGACATCGAGTCACTGTTTGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACGAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACTTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTACGTTCCATCGAAGCACTGTCAGAGCTCGACTCAGACCACCGACCTGTCCTTATGCAGCTCGGTCGCCCTCACAACCCAGCCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGAAGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCTATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCAAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCTCCGAACTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCGGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCCTAAGTGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCGTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGCACCCGGCTCCGACGGCATCCGCAACCGCGCGCTAAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCCCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCTAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCATCCCACTCCCTAATAGGCGCGCAAACACCTCCGCCGTTAGCCCCGTCACTCTCTTTGGCCAGCCCATACCGTGGGCCTCGCAGGTCAAATACCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATTAAAACGGTACGCGACCGTGCCGCCTTCATATTAGGACGTCTCTACCCTATGCTTTGCAAGCGAAGCAAACTGTCCCTCCGTAATAAGGTAACTCTCTACAAAACTTGCATACGCCCCGTTATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCGCACCAACTTGAAGCCCCTTCAGGTTATTCAATCCCGATTCTGCAGGATAGCCGTCGGAGCACCATGGTTCCTGAGGAACGTGGATCTCCACGATGACCTGGAGCTTGACTCTGTCAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTCTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MVRNDRLTASKGGTAIYYRRALHVVPLDTPSLLHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEALSELDSDHRPVLMQLGRPHNPATVTRTMVDWNKLGTCLAEAAPPILPYGPDSNLSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSSELRNLLRVRNAAIRAYDRLPTHSNRIRMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIRNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLPTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTSSIPLPNRRANTSAVSPVTLFGQPIPWASQVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCKRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTNLKPLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSVSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNF3   V5GNJ2   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   X1WLB2   A0A2S2Q383   A0A224XF24   Q07995   A0A3N5Z7I3   A0A224X6Q4   J9LC21   D7EM17   J9M522   A0A2S2QEE0   A0A2J7R7D0   A0A2S2NGV8   X1WNI2   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UGF5   A0A2J7PDM0   A0A1Y1LKN6   J9KKL3   X1WZH0   A0A224XB44   A0A2M4CV42   A0A2J7QR37   A0A2M4CV52   A0A224X6T4   A0A2J7PBY3   A0A2J7QY69   A0A224X6S1   A0A2S2N814   A0A2J7PU96   A0A2M4BEF4   A0A2M4BEZ9   K7IN67   A0A2H8TF37   A0A069DZL8   A0A0A9YJ00   A0A2M4BD67   A0A2J7PVX3   X1WQI9   A0A0A9YU04   A0A2M4BDV6   A0A2S2R9D4   A0A224XI99   A0A224X6U5   A0A0A9YSX4   A0A2J7PQB5   A0A2J7Q6J2   A0A2J7QB68   A0A2S2P698   A0A224X6R6   P21328   A0A1B6EGD8   A0A1Y1KFR3   P21329   J9LFC9   A0A0L0CBP5   A0A2S2PJG2   A0A224XJI0   A0A224X746   A0A2A4IUM2   A0A2S2NPG3   A0A0J7MYU2   J9JS95   A0A142LX26   A0A069DX78   D7GYA5   A0A087UCW3   A0A352X8G4   A0A2S2PA10   A0A224XHW8   A0A2S2N6Q7   Q95SX7   A0A2S2NPJ7   A0A2J7R8R8   A0A2A4K918   A0A2H8TKI9   A0A2S2PX53   A0A2J7Q0S7   A0A224XIB0  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    20075255    26334808    25401762    2463954    3040362    1714378    1701254    26108605    25527032    30148503    7753626    12537569   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    GALX01005299    JAB63167.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GBBI01004571    JAC14141.1    ABLF02042518    ABLF02057746    GGMS01002992    MBY72195.1    GFTR01008038    JAW08388.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    GFTR01008279    JAW08147.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    KQ973412    EFA12510.2    ABLF02024246    GGMS01006359    MBY75562.1    NEVH01006736    PNF36716.1    GGMR01003407    MBY16026.1    ABLF02008153    ABLF02008462    ABLF02008464    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    KK119692    KFM76444.1    NEVH01026386    PNF14434.1    GEZM01053022    JAV74219.1    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02034467    GFTR01008262    JAW08164.1    GGFL01005012    MBW69190.1    NEVH01011985    PNF31054.1    GGFL01004957    MBW69135.1    GFTR01008261    JAW08165.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    GFTR01008271    JAW08155.1    GGMR01000676    MBY13295.1    NEVH01021205    PNF19912.1    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GFXV01000908    MBW12713.1    GBGD01000415    JAC88474.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGFJ01001858    MBW50999.1    NEVH01020940    PNF20481.1    ABLF02022418    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GGFJ01001857    MBW50998.1    GGMS01017365    MBY86568.1    GFTR01008256    JAW08170.1    GFTR01008251    JAW08175.1    GBHO01008295    JAG35309.1    NEVH01022639    PNF18527.1    NEVH01017470    PNF24199.1    NEVH01016302    PNF25823.1    GGMR01012305    MBY24924.1    GFTR01008269    JAW08157.1    M22874    M38643    GEDC01000337    JAS36961.1    GEZM01084969    JAV60363.1    M38437    ABLF02023911    JRES01000644    KNC29657.1    GGMR01016905    MBY29524.1    GFTR01008257    JAW08169.1    GFTR01008151    JAW08275.1    NWSH01007753    PCG62823.1    GGMR01006408    MBY19027.1    LBMM01013518    KMQ85605.1    ABLF02028535    ABLF02028545    KU543673    AMS38352.1    GBGD01000389    JAC88500.1    KQ973363    EFA13335.2    KK119261    KFM75202.1    DNOY01000259    HBE18313.1    GGMR01013409    MBY26028.1    GFTR01008254    JAW08172.1    GGMR01000226    MBY12845.1    AY060438    AAL25477.1    GGMR01006491    MBY19110.1    NEVH01006721    PNF37225.1    NWSH01000032    PCG80496.1    GFXV01002840    MBW14645.1    GGMS01000737    MBY69940.1    NEVH01019963    PNF22185.1    GFTR01008246    JAW08180.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000037069    UP000218220    UP000036403   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    P21328    P21329    Q95SX7    + More

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNF3   V5GNJ2   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   X1WLB2   A0A2S2Q383   A0A224XF24   Q07995   A0A3N5Z7I3   A0A224X6Q4   J9LC21   D7EM17   J9M522   A0A2S2QEE0   A0A2J7R7D0   A0A2S2NGV8   X1WNI2   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UGF5   A0A2J7PDM0   A0A1Y1LKN6   J9KKL3   X1WZH0   A0A224XB44   A0A2M4CV42   A0A2J7QR37   A0A2M4CV52   A0A224X6T4   A0A2J7PBY3   A0A2J7QY69   A0A224X6S1   A0A2S2N814   A0A2J7PU96   A0A2M4BEF4   A0A2M4BEZ9   K7IN67   A0A2H8TF37   A0A069DZL8   A0A0A9YJ00   A0A2M4BD67   A0A2J7PVX3   X1WQI9   A0A0A9YU04   A0A2M4BDV6   A0A2S2R9D4   A0A224XI99   A0A224X6U5   A0A0A9YSX4   A0A2J7PQB5   A0A2J7Q6J2   A0A2J7QB68   A0A2S2P698   A0A224X6R6   P21328   A0A1B6EGD8   A0A1Y1KFR3   P21329   J9LFC9   A0A0L0CBP5   A0A2S2PJG2   A0A224XJI0   A0A224X746   A0A2A4IUM2   A0A2S2NPG3   A0A0J7MYU2   J9JS95   A0A142LX26   A0A069DX78   D7GYA5   A0A087UCW3   A0A352X8G4   A0A2S2PA10   A0A224XHW8   A0A2S2N6Q7   Q95SX7   A0A2S2NPJ7   A0A2J7R8R8   A0A2A4K918   A0A2H8TKI9   A0A2S2PX53   A0A2J7Q0S7   A0A224XIB0  

PDB

6AR3     E-value=0.00140776,     Score=102

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

899

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.05225

Exp number, first 60 AAs:

0.02127

Total prob of N-in:

0.02040

outside

1  -  899

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

17.042811

CSRT

0

Interpretation

Uncertain