Gene

KWMTBOMO01470

Pre Gene Modal

BGIBMGA009039

Annotation

PREDICTED:_neuromedin-B_receptor_[Amyelois_transitella]

Location

Bomo_Chr3(+):11894467-11922930      View in EpiBrowser

Full name

Neuropeptide CCHamide-1 receptor      

Location in the cell

PlasmaMembrane   Reliability : 4.985

CDS

ATGCAAGAAACGAACGAAACATATGATAACAGCACGGAGATCTACCAGCCCTACTACGAGAGGCCGGAGACCTACATCGTGCCAATACTTTTCGCTCTCATCTTCGTGATCGGTGTTGTAGGAAATGGTACCCTAGTAGCGGTCTTCGTTAGGCACAAGGCCATGAGAAACGTTCCAAATACTTACATTCTATCACTGGCCTTGGCTGATCTGCTAGTCATCATCACCTGCGTCCCCTTTACTTCGATCGTGTACACCGTGGAATCCTGGCCTTGGGGTAGGACTGTGTGCCAAGTGTCGGAAGCCGCCAAAGACGTCAGCATCGGAGTGTCAGTTTTCACCCTGACAGCGCTGTCAGCGGACAGATACTTCGCCATCGTAGATCCGCTGAGGAAACTACATGCAACAGGGAGCAGCAAGAGAGCCACACGCTTAACAATAGCTACAGCAATCGGGATATGGATATTGGCAGGTCTGCTGGCAACGCCCGCCTTCATCGGCTCCTACTTACGACCATTCGTTGTCAATCCAACTACACAGTTTCTCGTCTGCTACCCATACCCCCAAGAGTGGGGAGAACACTATGCCCAAATCGTGGTCATGGTGCGTTTTCTTCTCTACTACTCGTTGCCACTAGCTGTGATTGCGTTATTCTATGTACTCATGGCCTGGCATTTAGTGCTCAGTACTCAGAACATGCCTGGTGAAATGCAAGGGACTCAGCGACAGATGCGGGCGCGCAGGAAAGTCGCAGTAACTGTGCTGGCTTTCGTTCTGGTCTTTGCTGCCTGTTTCCTACCCTCACACGTCTTCATGATGTGGTTTTATTTTTGTCCAACGGCCGAAAATGATTATAACGGATGGTGGCACGGGCTCCGGATCGTCGGCTTCTGTCTTTCGTTCCTCAACAGCTGCGTCAATCCAATAGCTTTGTACTGCACCAGCGGAATCTTCAGGAAGCACTTTAACAGATATCTCCTTTGTCGAGGCAGCTCCACCCGCGGTGCTAGAGGATCCATGTCCCTCTCCACCTCGAGACGCTTGCATTCGAGTCGGAAGACCAACGTCAGCATGGTGCCCAGAACCACTAGCATGGGTCGTGACAGCAGCATTCGTCTGCTGAACAACGGCTCCTCGAAGCTCTGA

Protein

MQETNETYDNSTEIYQPYYERPETYIVPILFALIFVIGVVGNGTLVAVFVRHKAMRNVPNTYILSLALADLLVIITCVPFTSIVYTVESWPWGRTVCQVSEAAKDVSIGVSVFTLTALSADRYFAIVDPLRKLHATGSSKRATRLTIATAIGIWILAGLLATPAFIGSYLRPFVVNPTTQFLVCYPYPQEWGEHYAQIVVMVRFLLYYSLPLAVIALFYVLMAWHLVLSTQNMPGEMQGTQRQMRARRKVAVTVLAFVLVFAACFLPSHVFMMWFYFCPTAENDYNGWWHGLRIVGFCLSFLNSCVNPIALYCTSGIFRKHFNRYLLCRGSSTRGARGSMSLSTSRRLHSSRKTNVSMVPRTTSMGRDSSIRLLNNGSSKL

Description

Receptor for the neuropeptide CCHamide-1 (PubMed:21110953, PubMed:23293632). Plays a role in the modulation of starvation-induced olfactory behavior where starved flies show increased responsiveness to food odorants, repellants and pheromones (PubMed:24067446).

Similarity

Belongs to the G-protein coupled receptor 1 family.

Keywords

Cell membrane   Complete proteome   Disulfide bond   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Neuropeptide CCHamide-1 receptor

Uniprot

A0A2A4JRS4   B3XXM8   A0A0S1YD78   A0A194Q2N9   A0A2J7Q987   A0A139WD04   + More
A0A2P8YVS0   A0A0M5J7D6   A0A1I8PFK0   A0A1I8PFU4   A0A1I8NBY3   B3MIF2   B4J790   A0A182J0B4   A0A084WBF2   A0A1A9ZYI9   B4KN01   A0A1A9XP38   A0A1B0G0X0   A0A1A9W0W8   A0A1B0BUC5   B4MIS7   A0A1A9V9R2   A0A0Q9XL11   B4LNA0   A0A182MXX0   A0A1J1IU74   A0A182VM06   U3U959   A0A0L0CIV7   A1ZAX0   A0A0J9RF12   B4HMY2   A0A336KUH4   B4QBB3   A0A1W4VD97   A0A182H4I9   T1HUP6   B3NMK9   A0A182M7G7   B4P563   A0A182QV95   B4GIB2   A0A1B6ICU8   Q28Z40   A0A182LPJ0   A0A232FIS4   A0A2U9PG18   A0A1S3DS75   A0A3B0JQV9   A0A182FTD1   W8AWT5   K7ISZ8   A0A0R3NNC4   A0A067R841   A0A182U973   A0A182XCA9   A0A2J7Q927   A0A0R3NNK9   A0A3L8DXR0   A0A182WF52   U3U7M5   A0A0L7R6N8   A0A2S2PUK5   A0A026WMQ4   A0A023F665   A0A087ZN71   J9JWL6   A0A2R7W5T6   A0A195FTE2   E2AQW6   E0W1V3   A0A195B1K8   A0A158NZA0   A0A2U9PG12   T1H9A6   A0A2S2QMN0   F4WSD8   A0A2S2Q9P8   A0A2A3EAS0   A0A087ZMW0   A0A1S3D5Z2   J9JWZ2   A0A195CWL5   A0A2S2QN14   A0A1W4XJZ6   J9K4C0   D6WV75   A0A0L7R6T4   A0A194QHC7   V9I0H3   A0A1B0DR34   A0A154PF30   A0A3L8DX22   K7ISZ6   A0A026WQH4   A0A0N0PD66   E2AWG8   A0A2A3ECB8  

Pubmed

18725956    26354079    18362917    19820115    29403074    25315136    + More
17994087    24438588    18057021    23932938    26108605    21110953    10731132    12537572    23293632    24098432    24067446    22936249    26483478    17550304    15632085    23185243    20966253    28648823    24495485    20075255    24845553    30249741    24508170    25474469    20798317    20566863    21347285    21719571   

EMBL

NWSH01000696    PCG74737.1    AB330436    BAG68414.1    KT031013    ALM88311.1    + More
KQ459562    KPI99827.1    NEVH01016943    PNF25139.1    KQ971363    KYB25711.1    PYGN01000333    PSN48337.1    CP012524    ALC41974.1    CH902619    EDV37000.1    CH916367    EDW02108.1    ATLV01022348    ATLV01022349    ATLV01022350    KE525331    KFB47546.1    CH933808    EDW09923.1    KRG04984.1    CCAG010020384    JXJN01020601    CH963719    EDW72016.1    KRG04983.1    CH940648    EDW61052.1    CVRI01000059    CRL03743.1    AB817297    BAO01064.1    JRES01000335    KNC32186.1    AY842252    AE013599    AAX58700.1    CM002911    KMY94643.1    CH480816    EDW48332.1    UFQS01000834    UFQT01000834    SSX07155.1    SSX27498.1    CM000362    EDX07537.1    JXUM01109685    JXUM01109686    JXUM01109687    KQ565344    KXJ71074.1    ACPB03005213    CH954179    EDV54948.1    AXCM01002479    CM000158    EDW91764.1    AXCN02002114    CH479183    EDW36232.1    GECU01022948    JAS84758.1    CM000071    EAL25775.3    KRT02538.1    NNAY01000166    OXU30369.1    MG550203    AWT50637.1    OUUW01000001    SPP75051.1    GAMC01017302    JAB89253.1    AAZX01003325    KRT02536.1    KK852871    KDR14578.1    PNF25073.1    KRT02537.1    QOIP01000003    RLU25023.1    AB817298    BAO01065.1    KQ414646    KOC66557.1    GGMR01020385    MBY33004.1    KK107151    EZA57357.1    GBBI01002008    JAC16704.1    ABLF02022539    ABLF02022541    ABLF02022542    ABLF02022543    ABLF02034748    ABLF02053397    KK854364    PTY15097.1    KQ981276    KYN43723.1    GL441846    EFN64112.1    DS235873    EEB19547.1    KQ976681    KYM78170.1    ADTU01004183    ADTU01004184    MG550204    AWT50638.1    ACPB03005200    GGMS01009597    MBY78800.1    GL888321    EGI62855.1    GGMS01004729    MBY73932.1    KZ288302    PBC28827.1    ABLF02026605    ABLF02026606    KQ977220    KYN04927.1    GGMS01009895    MBY79098.1    ABLF02025044    EFA09272.1    KOC66558.1    KQ458860    KPJ04824.1    HQ703464    ADZ15314.1    AJVK01019613    AJVK01019614    AJVK01019615    KQ434890    KZC10422.1    RLU25020.1    AAZX01009174    EZA57359.1    KQ460366    KPJ15631.1    GL443287    EFN62213.1    PBC28826.1   

Proteomes

UP000218220    UP000053268    UP000235965    UP000007266    UP000245037    UP000092553    + More
UP000095300    UP000095301    UP000007801    UP000001070    UP000075880    UP000030765    UP000092445    UP000009192    UP000092443    UP000092444    UP000091820    UP000092460    UP000007798    UP000078200    UP000008792    UP000075884    UP000183832    UP000075903    UP000037069    UP000000803    UP000001292    UP000000304    UP000192221    UP000069940    UP000249989    UP000015103    UP000008711    UP000075883    UP000002282    UP000075886    UP000008744    UP000001819    UP000075882    UP000215335    UP000079169    UP000268350    UP000069272    UP000002358    UP000027135    UP000075902    UP000076407    UP000279307    UP000075920    UP000053825    UP000053097    UP000005203    UP000007819    UP000078541    UP000000311    UP000009046    UP000078540    UP000005205    UP000007755    UP000242457    UP000078542    UP000192223    UP000092462    UP000076502    UP000053240   

PRIDE

B3XXM8    A1ZAX0   

Pfam

PF00001   7tm_1        + More
PF00271   Helicase_C

Interpro

IPR017452   GPCR_Rhodpsn_7TM        + More
IPR000276   GPCR_Rhodpsn       
IPR001556   Bombsn_rcpt-like       
IPR000611   NPY_rcpt       
IPR027417   P-loop_NTPase       
IPR001650   Helicase_C       

SUPFAM

SSF52540   SSF52540       

CDD

cd00079  HELICc

ProteinModelPortal

A0A2A4JRS4   B3XXM8   A0A0S1YD78   A0A194Q2N9   A0A2J7Q987   A0A139WD04   + More
A0A2P8YVS0   A0A0M5J7D6   A0A1I8PFK0   A0A1I8PFU4   A0A1I8NBY3   B3MIF2   B4J790   A0A182J0B4   A0A084WBF2   A0A1A9ZYI9   B4KN01   A0A1A9XP38   A0A1B0G0X0   A0A1A9W0W8   A0A1B0BUC5   B4MIS7   A0A1A9V9R2   A0A0Q9XL11   B4LNA0   A0A182MXX0   A0A1J1IU74   A0A182VM06   U3U959   A0A0L0CIV7   A1ZAX0   A0A0J9RF12   B4HMY2   A0A336KUH4   B4QBB3   A0A1W4VD97   A0A182H4I9   T1HUP6   B3NMK9   A0A182M7G7   B4P563   A0A182QV95   B4GIB2   A0A1B6ICU8   Q28Z40   A0A182LPJ0   A0A232FIS4   A0A2U9PG18   A0A1S3DS75   A0A3B0JQV9   A0A182FTD1   W8AWT5   K7ISZ8   A0A0R3NNC4   A0A067R841   A0A182U973   A0A182XCA9   A0A2J7Q927   A0A0R3NNK9   A0A3L8DXR0   A0A182WF52   U3U7M5   A0A0L7R6N8   A0A2S2PUK5   A0A026WMQ4   A0A023F665   A0A087ZN71   J9JWL6   A0A2R7W5T6   A0A195FTE2   E2AQW6   E0W1V3   A0A195B1K8   A0A158NZA0   A0A2U9PG12   T1H9A6   A0A2S2QMN0   F4WSD8   A0A2S2Q9P8   A0A2A3EAS0   A0A087ZMW0   A0A1S3D5Z2   J9JWZ2   A0A195CWL5   A0A2S2QN14   A0A1W4XJZ6   J9K4C0   D6WV75   A0A0L7R6T4   A0A194QHC7   V9I0H3   A0A1B0DR34   A0A154PF30   A0A3L8DX22   K7ISZ6   A0A026WQH4   A0A0N0PD66   E2AWG8   A0A2A3ECB8  

PDB

6IGL     E-value=1.90551e-26,     Score=296

KEGG

100174919    K04170 bombesin receptor subtype-3 | (RefSeq) NGR-A15, BNGR-A15; neuropeptide receptor A15

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0008528   GO:0007218   GO:0005887   GO:0007186   GO:0004930   GO:0008188   GO:0008261   GO:0004983   GO:0050254   GO:0006420   GO:0004812   GO:0006418   GO:0006334   GO:0003779  

Subcellular location

Cell membrane  

Length:

381

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

155.64646

Exp number, first 60 AAs:

23.25084

Total prob of N-in:

0.08384

POSSIBLE N-term signal

sequence

outside

1  -  26

TMhelix

27  -  49

inside

50  -  61

TMhelix

62  -  84

outside

85  -  105

TMhelix

106  -  125

inside

126  -  144

TMhelix

145  -  167

outside

168  -  206

TMhelix

207  -  229

inside

230  -  249

TMhelix

250  -  272

outside

273  -  291

TMhelix

292  -  314

inside

315  -  381

 

 

Pi

251.327982

Theta

177.329544

Tajima's D

1.367263

CLR

0.125865

CSRT

0.754012299385031

Interpretation

Uncertain