Gene

KWMTBOMO01452  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008930

Annotation

putative_arginyl-tRNA_synthetase_[Operophtera_brumata]

Location

Bomo_Chr3(+):10914720-10916913      View in EpiBrowser

Full name

Arginine--tRNA ligase, cytoplasmic      

Alternative Name

Arginyl-tRNA synthetase

Location in the cell

Cytoplasmic   Reliability : 2.895

CDS

ATGACGGATATGAACGAAAAGAGGTTAGAAGAGCGAACCACCAGGGCCGAAAAAGAAGCCCGGGCTATCGAAGAAGAGCTAGAGAAATTAAGTAAAGGTGATCTTAGCTATGTCGGGAATCCAGAATTGGATAAGCTGCTGACCGAAAACGAAAAGCTCAAACATCGTCTCGCTATTCTTGAAAATGCCATAAAAGTAGAGACCGAATCTTCAGCGGCGATCAAGAAGGAAGCTAAAAAACGCACATTACCAATGCTTGTAACAGATACTAAGTCTGTTGAAAGTAATTTTTGCATATTAGAAGAACTGAAAAATCTTTTTGAAGTTGCCATTACCAATGCCTATCCAGATTTAGAGAATCCACCCATCGCACTGACGTTGTCAGGTAACAATCCTAAATTTGGAGATTATCAATGTAATTCTGCCATGGCCATAGCTCAGTTATTGAAGGCTAACAATGTAAAGACAAATCCCCGAGAAGTAGCTAATAACATACTAAACAAAACTCCAACATCACCAATAGTGCAAAGAATTGAAGTAGCTGGAGCAGGTTTCTTAAATATTCACTTGAATAAAGAATTTGTTGAACATGTTTTAAGTAGTATTTTAAAATCAGGCATCCAACCACCTGCAGTAAAGAAAGAAAAAGTTATTGTAGACTTTTCATCACCAAATATTGCAAAAGAAATGCATGTTGGCCATTTAAGGTCTACCATCATCGGTGACAGTATTTGTAGAGTGTTAGAATTTTTAAATAATGATGTGGTTAGGTTGAACCATTTGGGTGACTGGGGCACTCAGTTTGGAATGTTGATTGCTCATTTGCAAGATAAGTATCCAGATTTTAAAACGAAATCACCCCCAATATCTGATTTACAAGCATTTTATAAAGAGTCAAAGAAGAGATTTGATGAAGATGAAGAATTTAAAAAGCGAGCCTATTCATGTGTAGTACAGCTGCAGTCTCATCAACCAGATTACATTGCAGCATGGAAATTGATCTGTGAAGTATCTCGTCAAGAATTTCAGAAGATCTATGATCGGCTTGATATCAAAATCATAGACAGAGGTGAATCATTTTATCAAGACCGAATGGATGCTGTTGTACAGTTCTTAAAAGGAAAGGGCTTCTTAGAGGAAGATGAAGGAAGACTTATTATGTGGGGTAGTGAAAAACGTGAAGGTATACCGTTGACAGTTGTAAAATCTGATGGAGGTTACACGTATGATACATCTGATATGGCTGCTATAAAGCACAGGGTTGATGAGGAGAAAGCTAACCGTTTCATTTATGTTACTGATGTAGGCCAATACACTCATTTTATGACCATAGATGCCTGTGCAAGACGAGCTGGTATTCTCAAAGACGACCAGAGAGTTGAGCATGTTGGATTTGGTGTTGTTTTGGGAGAAGATAAGAAAAAATTTAAAACTAGGTCTGGTGATACCATAAAACTCATAGAGTTATTGGATGAAGGCCTGAAAAGATCTTTAGACAAGCTAGTTGAAAAGGGGCGTGATAAAGTGCTTAGTTCTGAGGAACTCAAGAGAGCTCAGGAAGCTGTAGCTTATGGCTGCATCAAGTATGCAGATCTATCGCACAACCGAATTAATGATTATATATTTTCATTTGACAAAATGCTCGATGACAAGGGCAATACTGCTGTCTATTTATTGTATGCATTAACTCGCATTAGATCGATTGCAAGGAATGCTCAGATATCATTAGATTCATTATTGGCAGAAGTCGATAGGATTGGATTGAAACTCACACATGAATCAGAGTGGAAGCTTGGAAAAACCCTGCTTAGGTTCCCTGAAGTCATATTGAAAGTATCTAGTGATTTGTACTTACATAGTTTATGTGAATATTTGTATGAGATATCCTCTGCTTTCACAGAATTTTATGATAAGTGCTTCTGTATCGAAAAGGATAAGGAAGGAAAGATTGTCAAGATAATTTATGAAAGATTAATGCTATGCGAAATCACAGCAAGAGTAATGGAAAAATCACTAGAAATTTTAGGAATCAAAACTGTATCAAAAATGTAG

Protein

MTDMNEKRLEERTTRAEKEARAIEEELEKLSKGDLSYVGNPELDKLLTENEKLKHRLAILENAIKVETESSAAIKKEAKKRTLPMLVTDTKSVESNFCILEELKNLFEVAITNAYPDLENPPIALTLSGNNPKFGDYQCNSAMAIAQLLKANNVKTNPREVANNILNKTPTSPIVQRIEVAGAGFLNIHLNKEFVEHVLSSILKSGIQPPAVKKEKVIVDFSSPNIAKEMHVGHLRSTIIGDSICRVLEFLNNDVVRLNHLGDWGTQFGMLIAHLQDKYPDFKTKSPPISDLQAFYKESKKRFDEDEEFKKRAYSCVVQLQSHQPDYIAAWKLICEVSRQEFQKIYDRLDIKIIDRGESFYQDRMDAVVQFLKGKGFLEEDEGRLIMWGSEKREGIPLTVVKSDGGYTYDTSDMAAIKHRVDEEKANRFIYVTDVGQYTHFMTIDACARRAGILKDDQRVEHVGFGVVLGEDKKKFKTRSGDTIKLIELLDEGLKRSLDKLVEKGRDKVLSSEELKRAQEAVAYGCIKYADLSHNRINDYIFSFDKMLDDKGNTAVYLLYALTRIRSIARNAQISLDSLLAEVDRIGLKLTHESEWKLGKTLLRFPEVILKVSSDLYLHSLCEYLYEISSAFTEFYDKCFCIEKDKEGKIVKIIYERLMLCEITARVMEKSLEILGIKTVSKM

Description

Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.

Catalytic Activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)

Subunit

Monomer; also part of a multisubunit complex that groups tRNA ligases for Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro.

Similarity

Belongs to the class-I aminoacyl-tRNA synthetase family.

Keywords

Aminoacyl-tRNA synthetase   ATP-binding   Complete proteome   Cytoplasm   Ligase   Nucleotide-binding   Protein biosynthesis   Reference proteome  

Feature

chain  Arginine--tRNA ligase, cytoplasmic

Uniprot

H9JHD3   A0A2H1WA27   A0A2A4K4Y4   A0A0L7L8Q8   A0A2W1BTT1   A0A194RLD4   + More
A0A194Q2Q5   A0A212FM01   S4PCD2   A0A1Y1NH99   A0A182H3D8   A0A232FJI9   Q17PZ4   K7J2L2   A0A1S4EV92   A0A1Q3EZX9   B0W0R1   A0A0J7L961   A0A2A3EG52   E2C789   A0A088AT21   A0A158P2C2   A0A182SD47   A0A0C9QK23   F4W6M7   A0A154P8I0   A0A0L7REU7   U5EN81   A0A182FLS0   A0A182QIH5   A0A195D4G8   A0A182K960   K4FUJ5   A0A2M4ADH3   A0A1I8MNG1   A0A2M4AD34   T1PG72   A0A182MEA7   A0A2M4AD10   W5N3M5   A0A182NN94   A0A182WAU8   A0A2M4BGE6   A0A2M4BGE0   A0A182TPQ5   A0A310SG68   Q7Q2L9   D2A3H2   A0A2M4BGQ4   A0A195BT73   U4UK14   W5JAR0   A0A1B6HRP2   W0FYJ9   A0A182XPR9   A0A1S2ZKV2   A0A195E4G6   A0A182R2V1   A0A1I8P1I0   A0A3L8DY34   A0A026WE39   A0A3B3ZI07   A0A0A1XT66   A0A2J7QW10   W8C227   A0A3B3E2V1   H2RMS4   L5L1P9   F7CK22   Q6P1S4   A0A1S3LSA1   F7EFE0   Q5XJ11   M7AK35   A0A2U9B714   B5X4E3   A0A0L0C0Q4   A0A1L8GVE9   Q4V7Z9   H3B800   A0A3P8SAA7   E2QRR5   A0A2Y9HV47   A0A2U3YFW9   A0A060X148   F6YPN7   A0A2R2MLW9   F1QLT9   A0A2R2MME5   A0A195FJV3   A0A2D4K4F9   A0A2U3VC21   A0A3B4VJH9   B2GT10   Q7ZVF4   A0A3B4ZCE1   A0A3B4YSS1   U3F975   A0A2Y9IKT8   A0A1U7TH09  

EC Number

6.1.1.19

Pubmed

19121390    26227816    28756777    26354079    22118469    23622113    + More
28004739    26483478    28648823    17510324    20075255    20798317    21347285    21719571    23056606    25315136    12364791    14747013    17210077    18362917    19820115    23537049    20920257    23761445    24446543    30249741    24508170    25463417    25830018    24495485    29451363    21551351    23258410    20431018    17495919    23624526    20433749    26108605    27762356    9215903    16341006    24755649    19892987    23594743    23915248   

EMBL

BABH01012472    ODYU01007282    SOQ49918.1    NWSH01000123    PCG79315.1    JTDY01002302    + More
KOB71704.1    KZ149902    PZC78478.1    KQ459989    KPJ18643.1    KQ459562    KPI99842.1    AGBW02007683    OWR54757.1    GAIX01005487    JAA87073.1    GEZM01006993    JAV95496.1    JXUM01107202    KQ565122    KXJ71316.1    NNAY01000114    OXU30845.1    CH477188    EAT48800.1    GFDL01014183    JAV20862.1    DS231818    EDS41363.1    LBMM01000233    KMR03562.1    KZ288254    PBC30753.1    GL453340    EFN76202.1    ADTU01007108    GBYB01003894    JAG73661.1    GL887707    EGI70362.1    KQ434844    KZC08151.1    KQ414609    KOC69271.1    GANO01000701    JAB59170.1    AXCN02001903    KQ976885    KYN07324.1    JX053407    AFK11635.1    GGFK01005469    MBW38790.1    GGFK01005370    MBW38691.1    KA647140    AFP61769.1    AXCM01012325    GGFK01005353    MBW38674.1    AHAT01005538    GGFJ01002989    MBW52130.1    GGFJ01002988    MBW52129.1    KQ773364    OAD52392.1    AAAB01008968    EAA13294.3    KQ971338    EFA01911.1    GGFJ01002990    MBW52131.1    KQ976408    KYM91163.1    KB632390    ERL94414.1    ADMH02001922    ETN60488.1    GECU01030376    JAS77330.1    KF419295    AHF48759.1    KQ979657    KYN19971.1    QOIP01000002    RLU25361.1    KK107250    EZA54370.1    GBXI01000529    JAD13763.1    NEVH01009768    PNF32779.1    GAMC01000673    JAC05883.1    KB030406    ELK17350.1    AAMC01076463    BC064888    BC083505    AAH83505.1    KB598656    EMP24739.1    CP026246    AWO99649.1    BT045912    ACI34174.1    JRES01001065    KNC25870.1    CM004471    OCT87804.1    BC097633    AAH97633.1    AFYH01036530    AFYH01036531    AFYH01036532    AFYH01036533    AFYH01036534    AAEX03003029    AAEX03003030    FR904748    CDQ71064.1    CT025907    CT027760    KQ981523    KYN40284.1    IACL01034202    LAB03607.1    BC165718    AAI65718.1    BC045884    AAH45884.1    GAEP01000164    JAB54657.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000053268    UP000007151    + More
UP000069940    UP000249989    UP000215335    UP000008820    UP000002358    UP000002320    UP000036403    UP000242457    UP000008237    UP000005203    UP000005205    UP000075901    UP000007755    UP000076502    UP000053825    UP000069272    UP000075886    UP000078542    UP000075881    UP000095301    UP000075883    UP000018468    UP000075884    UP000075920    UP000075902    UP000007062    UP000007266    UP000078540    UP000030742    UP000000673    UP000076407    UP000079721    UP000078492    UP000075900    UP000095300    UP000279307    UP000053097    UP000261520    UP000235965    UP000261560    UP000005226    UP000010552    UP000008143    UP000087266    UP000002280    UP000031443    UP000246464    UP000037069    UP000186698    UP000008672    UP000265080    UP000002254    UP000248481    UP000245341    UP000193380    UP000002281    UP000085678    UP000000437    UP000078541    UP000245340    UP000261420    UP000261360    UP000248482    UP000189704   

PRIDE

H9JHD3    Q6P1S4    E2QRR5    F1QLT9   

Pfam

PF03485   Arg_tRNA_synt_N        + More
PF00750   tRNA-synt_1d
PF05746   DALR_1
PF11764   N-SET
PF00076   RRM_1
PF00856   SET
PF17725   YBD
PF00168   C2

Interpro

IPR005148   Arg-tRNA-synth_N        + More
IPR008909   DALR_anticod-bd       
IPR035684   ArgRS_core       
IPR009080   tRNAsynth_Ia_anticodon-bd       
IPR036695   Arg-tRNA-synth_N_sf       
IPR014729   Rossmann-like_a/b/a_fold       
IPR001278   Arg-tRNA-ligase       
IPR001412   aa-tRNA-synth_I_CS       
IPR035979   RBD_domain_sf       
IPR001214   SET_dom       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR024657   COMPASS_Set1_N-SET       
IPR041086   YBD       
IPR035892   C2_domain_sf       
IPR037771   C2_WWC       
IPR036020   WW_dom_sf       
IPR000008   C2_dom       
IPR001202   WW_dom       

SUPFAM

SSF55190   SSF55190        + More
SSF47323   SSF47323       
SSF54928   SSF54928       
SSF51045   SSF51045       

Gene 3D

3.30.1360.70     3.40.50.620     3.30.70.330     2.60.40.150    

CDD

cd00671  ArgRS_core
cd08680  C2_Kibra
cd00201  WW

ProteinModelPortal

H9JHD3   A0A2H1WA27   A0A2A4K4Y4   A0A0L7L8Q8   A0A2W1BTT1   A0A194RLD4   + More
A0A194Q2Q5   A0A212FM01   S4PCD2   A0A1Y1NH99   A0A182H3D8   A0A232FJI9   Q17PZ4   K7J2L2   A0A1S4EV92   A0A1Q3EZX9   B0W0R1   A0A0J7L961   A0A2A3EG52   E2C789   A0A088AT21   A0A158P2C2   A0A182SD47   A0A0C9QK23   F4W6M7   A0A154P8I0   A0A0L7REU7   U5EN81   A0A182FLS0   A0A182QIH5   A0A195D4G8   A0A182K960   K4FUJ5   A0A2M4ADH3   A0A1I8MNG1   A0A2M4AD34   T1PG72   A0A182MEA7   A0A2M4AD10   W5N3M5   A0A182NN94   A0A182WAU8   A0A2M4BGE6   A0A2M4BGE0   A0A182TPQ5   A0A310SG68   Q7Q2L9   D2A3H2   A0A2M4BGQ4   A0A195BT73   U4UK14   W5JAR0   A0A1B6HRP2   W0FYJ9   A0A182XPR9   A0A1S2ZKV2   A0A195E4G6   A0A182R2V1   A0A1I8P1I0   A0A3L8DY34   A0A026WE39   A0A3B3ZI07   A0A0A1XT66   A0A2J7QW10   W8C227   A0A3B3E2V1   H2RMS4   L5L1P9   F7CK22   Q6P1S4   A0A1S3LSA1   F7EFE0   Q5XJ11   M7AK35   A0A2U9B714   B5X4E3   A0A0L0C0Q4   A0A1L8GVE9   Q4V7Z9   H3B800   A0A3P8SAA7   E2QRR5   A0A2Y9HV47   A0A2U3YFW9   A0A060X148   F6YPN7   A0A2R2MLW9   F1QLT9   A0A2R2MME5   A0A195FJV3   A0A2D4K4F9   A0A2U3VC21   A0A3B4VJH9   B2GT10   Q7ZVF4   A0A3B4ZCE1   A0A3B4YSS1   U3F975   A0A2Y9IKT8   A0A1U7TH09  

PDB

4R3Z     E-value=0,     Score=1879

KEGG

101737924    K01887 arginyl-tRNA synthetase [EC:6.1.1.19] | (RefSeq) arginine--tRNA ligase, cytoplasmic

PATHWAY

00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0005737   GO:0006420   GO:0004814   GO:0005524   GO:0003723   GO:0006412   GO:0004812   GO:0017101   GO:0005829   GO:0005654   GO:0000166   GO:0006418   GO:0006334   GO:0003779   GO:0016021  

PANTHER

PTHR11956  

Subcellular location

Cytoplasm  
Cytosol  

Length:

683

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00164

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00083

outside

1  -  683

 

 

Pi

268.224156

Theta

223.316994

Tajima's D

0.440179

CLR

0.198939

CSRT

0.491225438728064

Interpretation

Uncertain