Gene

KWMTBOMO01440  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008927

Annotation

PREDICTED:_actin-related_protein_2/3_complex_subunit_2_[Papilio_machaon]

Location

Bomo_Chr3(+):10782930-10792240      View in EpiBrowser

Full name

Arp2/3 complex 34 kDa subunit       + More
Actin-related protein 2/3 complex subunit 2      
Probable actin-related protein 2/3 complex subunit 2      

Alternative Name

Arp2/3 complex 34 kDa subunit

Location in the cell

Nuclear   Reliability : 2.581

CDS

ATGATCTTACTCGAGATCAATAATAGAATTATAGAAGAAACACTAACGGTTAAATATAAAAATGCACTGGCGCGCTTAAAGCCTGAGTCAATAGATGTTACTGTAGCTGATTTTGATGGAGTATTATTCCATATATCCAATGTCAATGGAGACAAAACCAAAGTTAGGGTTAGTATATCTTTGAAGTTCTACAAGCAATTAGAAGAACATGGAGCAGATGAGCTCCTCAAGAGGGTGTATGGACCCCTTCTTACTGAACCAGAGTCAGGTTACAATATCTCATTGCTCCTCGACATGGAAAACATTCCGGAAGACTGGGAGGATGTAGTGAAAAAAGTTGGTCTGTTGAAGAGGAATTGCTTTGCGTCGGTATTCGAACGTTACTTCAGACTGCAAGAGGACGGTGACGTCAGCCACAAGCGAGCCGTCATTAACTACCGACAGGATGAAACTTTATACGTTGAAGCGCAGGAAGATCGCGTGACTGTTGTGTTTTCAACAGTCTTTCGACACGAAGATGATATGGTCATTGGGAAAGTGTTTATGCAAGAACTGAAAGAGGGAAGAAGGGCGTCGCACACCGCACCTCAAGTGTTGTTTTCACACAAGGAGCCGCCGCTAGAACTGGTCGACACTGACGCCAGAGTGGGTGACAACATCAGCTACGTCACATTTGTGCTGTTCCCGCGGCACACGTGCGCGGCGGCGCGCGACAACACCATCGACCTGCTGCACATGTTCCGCGACTACCTGCACTACCACATCAAGTGCTCCAAGGTGTACGTGCACTCGCGCATGCGCGCCAAGGCCGGCGACCTGCTCAAGGTGCTCAACCGCGCGCGCCCGCACGCCGCCGCGCGCCCCTCCGAGCGCAAGACCATCACGGGCAGAACTTTTGTGAGAAGAGATTGA

Protein

MILLEINNRIIEETLTVKYKNALARLKPESIDVTVADFDGVLFHISNVNGDKTKVRVSISLKFYKQLEEHGADELLKRVYGPLLTEPESGYNISLLLDMENIPEDWEDVVKKVGLLKRNCFASVFERYFRLQEDGDVSHKRAVINYRQDETLYVEAQEDRVTVVFSTVFRHEDDMVIGKVFMQELKEGRRASHTAPQVLFSHKEPPLELVDTDARVGDNISYVTFVLFPRHTCAAARDNTIDLLHMFRDYLHYHIKCSKVYVHSRMRAKAGDLLKVLNRARPHAAARPSERKTITGRTFVRRD

Description

Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).

Subunit

Component of the Arp2/3 complex.

Similarity

Belongs to the ARPC2 family.

Keywords

Actin-binding   Complete proteome   Cytoplasm   Cytoskeleton   Reference proteome  

Feature

chain  Actin-related protein 2/3 complex subunit 2

Uniprot

H9JHD0   A0A2W1C025   A0A2A4JUB3   X4ZFY7   A0A2H1WTD6   A0A1E1WJ60   + More
A0A194Q4B4   A0A194RRI0   A0A212F6Q6   A0A069DS81   A0A0A9WND2   A0A0V0G7D1   A0A224XGP3   A0A1L8EHR5   A0A1I8NWH9   A0A0P4W3K4   R4G5H1   B4KEQ3   A0A1L8EDL5   A0A0L0CB56   T1PBK8   A0A0K8V590   A0A034WFM4   A0A1L8EHM8   A0A0A1XD20   D3TMA4   W8B7L1   A0A1L8EAJ8   E0VZB0   B3MMT9   R4WK82   B4JCD6   A0A1L8EAC2   A0A1S3DNI4   Q29KS9   B3NM17   A0A1B0GGR4   B4PBK5   A0A2J7QZT0   B4MZA3   X2JAI2   B4IFB9   B4QAJ5   Q9VIM5   A0A3B0JHC6   A0A182IT89   A0A1L8E5K8   A0A182NF22   A0A182M8Z8   A0A087UCQ4   A0A1Y9IZY9   A0A182V1T9   A0A182KUI4   A0A182I542   Q7PVX8   A0A1A9YFP2   A0A1B0APX2   A0A182RIZ2   Q17JV8   A0A023EP38   T1DEL6   A0A1A9VH82   A0A2M4ALU9   A0A1A9WME1   A0A1B0AGT8   A0A2M3Z9W4   A0A0R3NUX3   W5JFG8   A0A182F2G6   A0A182PZH3   A0A1Q3FWV6   A0A1Q3FWV2   U5EZ72   A0A3Q0JHD0   A0A1J1HJX8   A0A1W4UP04   T1DP23   A0A1B6E4U4   A0A067RE18   A0A1B6MQD6   A0A0P6DVD5   A0A0N8AV38   A0A0P5GLT5   A0A182SI81   A0A0P5TEQ6   A0A0P4Y2K9   A0A1B6EJM6   A0A0P5M248   A0A0M4EPZ6   A0A182TY73   A0A0P5BS35   E9GZV8   A0A1Y1L7S4   A0A182YCI2   A0A0P5YP52   A0A0N8CS86   A0A293LNU5   A2I425   A0A218VB06   A0A3M0L6K4  

Pubmed

19121390    28756777    26354079    22118469    26334808    25401762    + More
26823975    27129103    17994087    26108605    25315136    25348373    25830018    20353571    24495485    20566863    23691247    15632085    23185243    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    12537569    20966253    12364791    17510324    24945155    24330624    20920257    23761445    24845553    21292972    28004739    25244985   

EMBL

BABH01012484    KZ149902    PZC78470.1    NWSH01000622    PCG75214.1    KJ187400    + More
AHV90275.1    ODYU01010861    SOQ56226.1    GDQN01004118    JAT86936.1    KQ459562    KPI99849.1    KQ459989    KPJ18651.1    AGBW02009978    OWR49426.1    GBGD01002303    JAC86586.1    GBHO01034330    GBRD01002087    GDHC01009878    JAG09274.1    JAG63734.1    JAQ08751.1    GECL01002877    JAP03247.1    GFTR01004769    JAW11657.1    GFDG01000578    JAV18221.1    GDKW01000573    JAI56022.1    ACPB03014449    GAHY01000575    JAA76935.1    CH933807    EDW12953.1    GFDG01001989    JAV16810.1    JRES01000753    KNC28704.1    KA646151    AFP60780.1    GDHF01025666    GDHF01018401    JAI26648.1    JAI33913.1    GAKP01006379    GAKP01006378    JAC52573.1    GFDG01000582    JAV18217.1    GBXI01005430    JAD08862.1    CCAG010001281    EZ422556    ADD18832.1    GAMC01013527    JAB93028.1    GFDG01003173    JAV15626.1    DS235851    EEB18716.1    CH902620    EDV30964.1    AK418010    BAN21225.1    CH916368    EDW04169.1    GFDG01003233    JAV15566.1    CH379061    EAL33095.1    KRT04733.1    CH954179    EDV54553.1    AJWK01000609    AJWK01000610    CM000158    EDW90519.1    NEVH01009067    PNF34064.1    CH963913    EDW77376.1    AE014134    AHN54616.1    CH480833    EDW46341.1    CM000361    CM002910    EDX05612.1    KMY91161.1    AY060391    OUUW01000006    SPP81804.1    GFDF01000128    JAV13956.1    AXCM01002215    KK119233    KFM75143.1    APCN01003776    AAAB01008984    JXJN01001604    CH477230    EAT46954.1    GAPW01002857    GEHC01000018    JAC10741.1    JAV47627.1    GALA01000982    JAA93870.1    GGFK01008438    MBW41759.1    GGFM01004575    MBW25326.1    KRT04732.1    ADMH02001553    ETN62083.1    AXCN02000831    GFDL01002986    JAV32059.1    GFDL01002988    JAV32057.1    GANO01001317    JAB58554.1    CVRI01000001    CRK86553.1    GAMD01002335    JAA99255.1    GEDC01004346    JAS32952.1    KK852521    KDR22101.1    GEBQ01031448    GEBQ01001823    JAT08529.1    JAT38154.1    GDIQ01184021    GDIQ01071723    JAN23014.1    GDIQ01239955    JAK11770.1    GDIQ01239956    JAK11769.1    GDIQ01098302    GDIP01127508    LRGB01000149    JAL53424.1    JAL76206.1    KZS20567.1    GDIP01242812    JAI80589.1    GECZ01031631    GECZ01022260    GECZ01018772    GECZ01012716    GECZ01006932    JAS38138.1    JAS47509.1    JAS50997.1    JAS57053.1    JAS62837.1    GDIQ01162177    JAK89548.1    CP012523    ALC38757.1    GDIP01181598    JAJ41804.1    GL732579    EFX74988.1    GEZM01066300    GEZM01066298    JAV67985.1    GDIP01056421    JAM47294.1    GDIP01103959    JAL99755.1    GFWV01004791    MAA29521.1    EF070528    ABM55594.1    MUZQ01000015    OWK63173.1    QRBI01000096    RMC18660.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000095300    + More
UP000015103    UP000009192    UP000037069    UP000095301    UP000092444    UP000009046    UP000007801    UP000001070    UP000079169    UP000001819    UP000008711    UP000092461    UP000002282    UP000235965    UP000007798    UP000000803    UP000001292    UP000000304    UP000268350    UP000075880    UP000075884    UP000075883    UP000054359    UP000076407    UP000075903    UP000075882    UP000075840    UP000007062    UP000092443    UP000092460    UP000075900    UP000008820    UP000078200    UP000091820    UP000092445    UP000000673    UP000069272    UP000075886    UP000183832    UP000192221    UP000027135    UP000075901    UP000076858    UP000092553    UP000075902    UP000000305    UP000076408    UP000197619    UP000269221   

PRIDE

H9JHD0    X2JAI2    Q9VIM5    Q7PVX8   

Pfam

PF04045   P34-Arc        + More
PF16038   TMIE

Interpro

IPR034666   ARPC2/4        + More
IPR007188   ARPC2       
IPR032006   TMIE       

SUPFAM

SSF69645   SSF69645       

Gene 3D

3.30.1460.20    

ProteinModelPortal

H9JHD0   A0A2W1C025   A0A2A4JUB3   X4ZFY7   A0A2H1WTD6   A0A1E1WJ60   + More
A0A194Q4B4   A0A194RRI0   A0A212F6Q6   A0A069DS81   A0A0A9WND2   A0A0V0G7D1   A0A224XGP3   A0A1L8EHR5   A0A1I8NWH9   A0A0P4W3K4   R4G5H1   B4KEQ3   A0A1L8EDL5   A0A0L0CB56   T1PBK8   A0A0K8V590   A0A034WFM4   A0A1L8EHM8   A0A0A1XD20   D3TMA4   W8B7L1   A0A1L8EAJ8   E0VZB0   B3MMT9   R4WK82   B4JCD6   A0A1L8EAC2   A0A1S3DNI4   Q29KS9   B3NM17   A0A1B0GGR4   B4PBK5   A0A2J7QZT0   B4MZA3   X2JAI2   B4IFB9   B4QAJ5   Q9VIM5   A0A3B0JHC6   A0A182IT89   A0A1L8E5K8   A0A182NF22   A0A182M8Z8   A0A087UCQ4   A0A1Y9IZY9   A0A182V1T9   A0A182KUI4   A0A182I542   Q7PVX8   A0A1A9YFP2   A0A1B0APX2   A0A182RIZ2   Q17JV8   A0A023EP38   T1DEL6   A0A1A9VH82   A0A2M4ALU9   A0A1A9WME1   A0A1B0AGT8   A0A2M3Z9W4   A0A0R3NUX3   W5JFG8   A0A182F2G6   A0A182PZH3   A0A1Q3FWV6   A0A1Q3FWV2   U5EZ72   A0A3Q0JHD0   A0A1J1HJX8   A0A1W4UP04   T1DP23   A0A1B6E4U4   A0A067RE18   A0A1B6MQD6   A0A0P6DVD5   A0A0N8AV38   A0A0P5GLT5   A0A182SI81   A0A0P5TEQ6   A0A0P4Y2K9   A0A1B6EJM6   A0A0P5M248   A0A0M4EPZ6   A0A182TY73   A0A0P5BS35   E9GZV8   A0A1Y1L7S4   A0A182YCI2   A0A0P5YP52   A0A0N8CS86   A0A293LNU5   A2I425   A0A218VB06   A0A3M0L6K4  

PDB

6DEC     E-value=1.19501e-117,     Score=1081

KEGG

101738677    K05758 actin related protein 2/3 complex, subunit 2 | (RefSeq) actin-related protein 2/3 complex sub

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0030041   GO:0005885   GO:0003779   GO:0005737   GO:0034314   GO:0000902   GO:0008360   GO:0030031   GO:0030866   GO:0005200   GO:0045179   GO:0051015   GO:0005856   GO:0016021   GO:0005925   GO:0036195   GO:0005768   GO:0010592   GO:0030027   GO:0098978   GO:1900026   GO:0015629   GO:0030833   GO:0006511   GO:0016787   GO:0016491   GO:0016651   GO:0006334  

PANTHER

PTHR12058  

Subcellular location

  

Length:

303

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00039

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.02632

outside

1  -  303

 

 

Pi

337.671102

Theta

203.702028

Tajima's D

2.253314

CLR

0.031991

CSRT

0.917854107294635

Interpretation

Uncertain