Gene

KWMTBOMO01431  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008955

Annotation

PREDICTED:_voltage-dependent_anion-selective_channel-like_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr3(-):10670961-10673069      View in EpiBrowser

Full name

Voltage-dependent anion-selective channel      

Alternative Name

DmVDAC
Porin

Location in the cell

Cytoplasmic   Reliability : 1.025 Mitochondrial   Reliability : 1.428

CDS

ATGGCTCCCCCATATTATGCTGACCTTGGAAAGAAGGCCAATGATGTCTTCAGCAAGGGCTATCACTTTGGTGTTTTCAAACTCGACCTGAAGACCAAGAGCGAGTCTGGTGTTGAATTCACCAGCGGAATCACCTCCAACCAGGAAAGCGGAAAGGTTTTTGGCAGCCTTTCCTCCAAATTTGCAGTGAAAGACTATGGCTTGACTTTCACAGAGAAGTGGAACACAGACAATACATTAGCTACTGACATCACAATCCAGGACAAGATTGCTGCTGGCCTTAAAGTCACCCTTGAAGGCACTTTTGCCCCACAGACTGGAACTAAAACTGGAAAATTGAAGACCTCATTCACCAATGACACAGTAGCAGTGAACACTAACTTGGATCTGGACTTGGCCGGTCCAGTTGTAGACGTTGCAGCAGTACTAAACTACCAGGGTTGGCTGGCTGGTGTACACACCCAGTTTGATACACAAAAAGCAAAGTTCTCCAAGAACAACTTTGCTCTAGGTTACCAATCTGGTGACTTTGCTCTCCACACAAACGTGTAA

Protein

MAPPYYADLGKKANDVFSKGYHFGVFKLDLKTKSESGVEFTSGITSNQESGKVFGSLSSKFAVKDYGLTFTEKWNTDNTLATDITIQDKIAAGLKVTLEGTFAPQTGTKTGKLKTSFTNDTVAVNTNLDLDLAGPVVDVAAVLNYQGWLAGVHTQFDTQKAKFSKNNFALGYQSGDFALHTNV

Description

Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.

Subunit

Interacts with hexokinases.

Similarity

Belongs to the eukaryotic mitochondrial porin family.

Keywords

Complete proteome   Direct protein sequencing   Ion transport   Membrane   Mitochondrion   Mitochondrion outer membrane   Porin   Reference proteome   Transmembrane   Transmembrane beta strand   Transport  

Feature

chain  Voltage-dependent anion-selective channel

Uniprot

H9JHF8   A0A3G1T1A5   I4DIN0   I4DMY5   S4PE81   A0A194RRI9   + More
A0A212ELN3   A0A2A4JUY7   A0A194Q2T9   F5BYI4   A0A2H1WGN4   G9D4X9   G9D4Y6   M9UVR1   G9D4Z1   G9D4Y7   G9D4Y8   G9D4Y9   G9D4Y3   G9D4Y5   G9D4Y4   G9D4Z0   G9D4Y2   G9D4Y1   G9D4Y0   G9D4X8   A0A1E1W0C2   A0A0L7LL04   A0A067RGH4   D6WWM0   A0A1Y1LHV8   R4UL09   A0A0T6AV30   A0A1W7R5C1   Q1HR57   T1E288   A0A0K8TPK4   A0A0L7K380   A0A1L8DFC5   U5EXM9   A0A0Q9X7X1   B0W1Q3   A0A182S5C8   A0A0M4E0L0   B4KKL9   A0A1Q3FA20   B3N522   A0A0Q9WMZ9   T1PH70   B4LS66   B4JPU9   A0A0N8NZC4   A0A1W4W540   B4P128   B4HWW8   B4Q9U9   M9PD75   Q94920   A0A336LRI7   B4MU45   E7E1I1   A0A182Q6R3   V5GAP6   B3MJX1   A0A1I8NMQ9   T1DN92   A0A2M3Z1S2   A0A2M4A1D6   W5J674   A0A182PLM3   Q8T4K0   M1PVC8   A0A0K8VR09   A0A154P050   A0A0L0BZA3   A0A0P6JNW5   A0A1L8EF26   A0A310SFZ5   A0A3B0KDK5   Q29KP2   B4GT11   A0A034VIH3   A0A0A1WYX5   A0A0C9QJQ5   A0A0K8WB92   A0A1A9UQZ2   A0A1B0A3W8   D3TRY2   A0A1A9XVS5   A0A1A9WUX9   A0A1B0ANX2   A0A1B0D6Z8   A0A0K8UT85   A0A0K8U7U2   A0A0L7RA93   A0A182F1W2   A0A093JJX6   A0A091RU79   K7FB26   K7FB35  

Pubmed

19121390    22651552    23622113    26354079    22118469    21452889    + More
28756777    21967427    26227816    24845553    18362917    19820115    28004739    17204158    17510324    24330624    26369729    17994087    25315136    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    9271262    8797793    9688565    10071211    12537569    20920257    23761445    12364791    14604798    14747013    17210077    23390104    26108605    15632085    25348373    25830018    20353571    17381049   

EMBL

BABH01012494    MG846912    AXY94764.1    AK401148    BAM17770.1    AK402653    + More
BAM19275.1    GAIX01003276    JAA89284.1    KQ459989    KPJ18661.1    AGBW02014011    OWR42396.1    NWSH01000622    PCG75212.1    KQ459562    KPI99861.1    JF417989    KZ149902    AEB26320.1    PZC78459.1    ODYU01008542    SOQ52231.1    JF777382    AEU11727.1    JF777389    AEU11734.1    KC477227    AGJ70167.1    JF777394    AEU11739.1    JF777390    AEU11735.1    JF777391    AEU11736.1    JF777392    AEU11737.1    JF777386    AEU11731.1    JF777388    AEU11733.1    JF777387    AEU11732.1    JF777393    AEU11738.1    JF777385    AEU11730.1    JF777384    AEU11729.1    JF777383    AEU11728.1    JF777381    AEU11726.1    GDQN01010617    GDQN01004761    JAT80437.1    JAT86293.1    JTDY01000739    KOB76044.1    KK852699    KDR18209.1    KQ971361    EFA08733.2    GEZM01058079    JAV71920.1    KC741000    AGM32824.1    LJIG01022745    KRT78938.1    GEHC01001257    JAV46388.1    DQ440237    EF446618    CH477229    ABF18270.1    ABO31104.1    EAT46997.1    GALA01000959    JAA93893.1    GDAI01001314    JAI16289.1    JTDY01015677    KOB51937.1    GFDF01008946    JAV05138.1    GANO01000875    JAB58996.1    CH933807    KRG03385.1    DS231823    EDS26604.1    CP012523    ALC38691.1    EDW12683.2    GFDL01010676    JAV24369.1    CH954177    EDV58967.1    CH940649    KRF81845.1    KA647465    AFP62094.1    EDW64752.1    CH916372    EDV98929.1    CH902620    KPU73932.1    CM000157    EDW88003.1    CH480818    EDW52513.1    CM000361    CM002910    EDX04616.1    KMY89634.1    AE014134    AFH03635.1    AGB92900.1    U70314    X92408    X95692    AJ000880    AY070509    BT024247    UFQT01000134    SSX20632.1    CH963852    EDW75634.1    HQ588352    ADT92003.1    AXCN02000699    GALX01001271    JAB67195.1    EDV32426.1    GAMD01003090    JAA98500.1    GGFM01001731    MBW22482.1    GGFK01001303    MBW34624.1    ADMH02002142    GGFL01004208    ETN58314.1    MBW68386.1    AY082909    AY137768    DQ999006    AAAB01008980    AAL89811.1    ABJ99082.1    EAA14314.2    KC109792    AGF80275.1    GDHF01011000    JAI41314.1    KQ434787    KZC05295.1    JRES01001119    KNC25360.1    GDIQ01002083    JAN92654.1    GFDG01001513    JAV17286.1    KQ764772    OAD54390.1    OUUW01000006    SPP81738.1    CH379061    EAL33131.1    CH479189    EDW25520.1    GAKP01017604    JAC41348.1    GBXI01010669    JAD03623.1    GBYB01000797    JAG70564.1    GDHF01003888    JAI48426.1    CCAG010021908    EZ424184    ADD20460.1    JXJN01001068    AJVK01003837    GDHF01022412    JAI29902.1    GDHF01029668    JAI22646.1    KQ414620    KOC67671.1    KK577238    KFW11219.1    KK708655    KFQ32002.1    AGCU01020592    AGCU01020593   

Proteomes

UP000005204    UP000053240    UP000007151    UP000218220    UP000053268    UP000037510    + More
UP000027135    UP000007266    UP000008820    UP000009192    UP000002320    UP000075900    UP000092553    UP000008711    UP000008792    UP000095301    UP000001070    UP000007801    UP000192221    UP000002282    UP000001292    UP000000304    UP000000803    UP000007798    UP000075886    UP000095300    UP000000673    UP000075885    UP000007062    UP000076502    UP000037069    UP000268350    UP000001819    UP000008744    UP000078200    UP000092445    UP000092444    UP000092443    UP000091820    UP000092460    UP000092462    UP000053825    UP000069272    UP000007267   

PRIDE

H9JHF8    M9PD75    Q94920   

Pfam

PF01459   Porin_3        + More
PF01399   PCI
PF18420   CSN4_RPN5_eIF3a

Interpro

IPR001925   Porin_Euk        + More
IPR023614   Porin_dom_sf       
IPR030271   VDAC3       
IPR027246   Porin_Euk/Tom40       
IPR030277   VDAC2       
IPR000717   PCI_dom       
IPR036390   WH_DNA-bd_sf       
IPR036388   WH-like_DNA-bd_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR041406   CSN4_HTH       
IPR040134   PSMD12/CSN4       
IPR037754   CSN4       

SUPFAM

SSF46785   SSF46785       

Gene 3D

2.40.160.10     1.10.10.10     1.25.40.10    

ProteinModelPortal

H9JHF8   A0A3G1T1A5   I4DIN0   I4DMY5   S4PE81   A0A194RRI9   + More
A0A212ELN3   A0A2A4JUY7   A0A194Q2T9   F5BYI4   A0A2H1WGN4   G9D4X9   G9D4Y6   M9UVR1   G9D4Z1   G9D4Y7   G9D4Y8   G9D4Y9   G9D4Y3   G9D4Y5   G9D4Y4   G9D4Z0   G9D4Y2   G9D4Y1   G9D4Y0   G9D4X8   A0A1E1W0C2   A0A0L7LL04   A0A067RGH4   D6WWM0   A0A1Y1LHV8   R4UL09   A0A0T6AV30   A0A1W7R5C1   Q1HR57   T1E288   A0A0K8TPK4   A0A0L7K380   A0A1L8DFC5   U5EXM9   A0A0Q9X7X1   B0W1Q3   A0A182S5C8   A0A0M4E0L0   B4KKL9   A0A1Q3FA20   B3N522   A0A0Q9WMZ9   T1PH70   B4LS66   B4JPU9   A0A0N8NZC4   A0A1W4W540   B4P128   B4HWW8   B4Q9U9   M9PD75   Q94920   A0A336LRI7   B4MU45   E7E1I1   A0A182Q6R3   V5GAP6   B3MJX1   A0A1I8NMQ9   T1DN92   A0A2M3Z1S2   A0A2M4A1D6   W5J674   A0A182PLM3   Q8T4K0   M1PVC8   A0A0K8VR09   A0A154P050   A0A0L0BZA3   A0A0P6JNW5   A0A1L8EF26   A0A310SFZ5   A0A3B0KDK5   Q29KP2   B4GT11   A0A034VIH3   A0A0A1WYX5   A0A0C9QJQ5   A0A0K8WB92   A0A1A9UQZ2   A0A1B0A3W8   D3TRY2   A0A1A9XVS5   A0A1A9WUX9   A0A1B0ANX2   A0A1B0D6Z8   A0A0K8UT85   A0A0K8U7U2   A0A0L7RA93   A0A182F1W2   A0A093JJX6   A0A091RU79   K7FB26   K7FB35  

PDB

4BUM     E-value=4.31384e-53,     Score=521

KEGG

101739703    K15040 voltage-dependent anion channel protein 2 | (RefSeq) voltage-dependent anion-selective channe

GO

GO:0005741   GO:0008308   GO:1902017   GO:0016006   GO:0007291   GO:0030382   GO:0007602   GO:0046930   GO:0015288   GO:0007005   GO:0006811   GO:0006839   GO:0005739   GO:0008180   GO:0007612   GO:0007270   GO:0001662   GO:0006820   GO:0016020   GO:0042773   GO:0016491   GO:0016651   GO:0006334   GO:0003779   GO:0016021   GO:0055085   GO:0098656  

PANTHER

PTHR11743   PTHR11743:SF28   PTHR11743:SF12   PTHR10855:SF2   PTHR10855  

Subcellular location

Mitochondrion outer membrane  
Cytoplasm  

Length:

183

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04063

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03390

outside

1  -  183

 

 

Pi

229.293075

Theta

201.953756

Tajima's D

0.560081

CLR

0.024559

CSRT

0.532623368831558

Interpretation

Uncertain