SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01387
Pre Gene Modal
BGIBMGA008977
Annotation
PREDICTED:_peptidyl-prolyl_cis-trans_isomerase-like_4_[Papilio_machaon]
Full name
Peptidyl-prolyl cis-trans isomerase      
Location in the cell
Nuclear   Reliability : 4.568
 

Sequence

CDS
ATGTCAGTCGTTATAGAAACAACTCTAGGCGATATTACCGTTGACTTGTATCTAGATCAGCGTCCTGTAACATGTTTGAATTTTTTGAAACTATGCAAAATGAAATATTACAATTACAATTTGTTTCATTCGATAAGAAGCAGCTTTATCGCTCAAACTGGTGACCCCACCGGTGAAGGTTCAGGGGGAATGTCTATATTTGGAATTCTTGAAGGTCCAGACAAACGATTGTTTTCTGGTGAGAAAATGCCAAAAATTCGGCACACTGATGCTGGGTTATTGTCAATGGTTTGTACTGGAGACATGATGATTGGTTCACAGTTCTTTTTTACTCTCGCTCCTGACTTGGACTCGTTAGATGGGATACATTGTGTCATAGGAGAAGTCACAGAAGGACATGATGTACTAAGAAAACTCAATGATGTGATATGTGATGAGACTCATCGCCCTTATCGTGATGTCAGAATAACACACACTGTAGTGTTAGAGGATCCTTTTAATGATCCTCCAGGTCTAAGAGCTCCTTCGCGATCTCCTTCTCCTACTGCAGAAAGGTTGAAGGGTGGGAGAATAGCACCTGATGAGGAAATAGATGAAACTCAAGGCAAGAGCACAGCTGAAGTACAAGAGATTATTGAGGAAAAAGAGGCCAAAGCTAGAGCAACTATTCTTGAAATTATTGGTGATATTCCTGATGCTGACATTGCTCCTCCTGAAAATGTACTCTTTGTTTGCAAGCTAAATCCAGTCACAACAGATGACGATCTTGAAATCATATTTAGTCGATTTGGTAAAATAGTAAGTTGTGAAGTGATAAGAGATAAAAAGAGTGGTGATTCTTTGCAATATGCTTTTATTGAGTTTGCTGATAAAAAGTCATGTGAAGATGCCTATTTTAAAATGGATAATGTGCTTATTGATGACCGAAGAATACATGTTGACTTCTCCCAGTCTGTATCGAAAATAAAGTGGCTAGGAAAAGGTAGAGGGGTTAAGCTAATAAATGAATCGGAAGAAGAAGAAGGCTCTAAAAATAAATCTAGATATACTAGTAGAGAAAGAGATCATAGGAATGGTAGAGATTATAATCTTAAAAGGGAAAATTACGAACAAGAAAGAAATGAAAGGGAATGGTCAAAACGAAATAAAAATGAAAAAAATATTGATAAACATGGTCACGTTCAGAATCTGGCTGCAAGAGATCATAGGAAACACACAAGCCACAAAGATACACAAAGAAAAGATTCTGATAGATATGATAAAGATATACCAAAGGAAGATAAAAGACATAAAGAACATAGTGAAAGAAAGGACAATGTTACAGAGAGTAAGAGACTTAAGGAGCATGAAGTGTGTAGTAAGACTGAAAATCATAAAATTAAACATAGAGAAGCTAGTCGTAAACACCAAGATAGACACAACTCTGAGTATGCTGAAAATGATGAGAAAGAGAAAAGAAATAGTATAAAACATAGAGACTACCATACAAAAGAGCGTTCACATGACAATGAAAATTCTAAAAATAACGAAAAAAATTACAATGTAACACAGAAACATAAAGAACATACAAAGCATTCCCAGAAGTATATGGTTGATAAAAGTACAGAAAAAAAATTAAGTAGAAAAGATGATAAATCCAAATTGAAAAGAAAGTATGATAAGTCTCCAAAAAGAGAACACAAGAAACGAGATTCATCTTGTGACTTAGAGCCCAAAACACCATCACCTGTTACAAATAAAAAGAGTAGATCTGAAAAAAGAAAGAAACAAACAAAGAAAAGACAACATAAGAAACGCAAACAATCTACCTCTTCTTCTTCAGAAAGTGATTCCTCAGAAACAAGTTCATCTAGTACAGAGTCTAGTTCGTCCAGTGAAGATAACAGGAAAAGAAAGTCAAAAAAAAGAAAAAGAAGCTCCTCCTCTTCAAGCACTTCCAGTAGTAGTGATAGCAGTTCTTCTAGTAGCTCATCAAGCAGTACTTCCAGTTCAGATTCTGAAGCTGACAGGAAAAAAAGGAGAAAGAAGGCTATAAAAAAGAAGAGCAGATAG
Protein
MSVVIETTLGDITVDLYLDQRPVTCLNFLKLCKMKYYNYNLFHSIRSSFIAQTGDPTGEGSGGMSIFGILEGPDKRLFSGEKMPKIRHTDAGLLSMVCTGDMMIGSQFFFTLAPDLDSLDGIHCVIGEVTEGHDVLRKLNDVICDETHRPYRDVRITHTVVLEDPFNDPPGLRAPSRSPSPTAERLKGGRIAPDEEIDETQGKSTAEVQEIIEEKEAKARATILEIIGDIPDADIAPPENVLFVCKLNPVTTDDDLEIIFSRFGKIVSCEVIRDKKSGDSLQYAFIEFADKKSCEDAYFKMDNVLIDDRRIHVDFSQSVSKIKWLGKGRGVKLINESEEEEGSKNKSRYTSRERDHRNGRDYNLKRENYEQERNEREWSKRNKNEKNIDKHGHVQNLAARDHRKHTSHKDTQRKDSDRYDKDIPKEDKRHKEHSERKDNVTESKRLKEHEVCSKTENHKIKHREASRKHQDRHNSEYAENDEKEKRNSIKHRDYHTKERSHDNENSKNNEKNYNVTQKHKEHTKHSQKYMVDKSTEKKLSRKDDKSKLKRKYDKSPKREHKKRDSSCDLEPKTPSPVTNKKSRSEKRKKQTKKRQHKKRKQSTSSSSESDSSETSSSSTESSSSSEDNRKRKSKKRKRSSSSSSTSSSSDSSSSSSSSSSTSSSDSEADRKKRRKKAIKKKSR

Summary

Description
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Catalytic Activity
[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)
Similarity
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
EC Number
5.2.1.8
Pfam
PF00076   RRM_1        + More
PF00160   Pro_isomerase
Interpro
IPR035538   Cyclophilin_PPIL4        + More
IPR029000   Cyclophilin-like_dom_sf       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR035979   RBD_domain_sf       
IPR000504   RRM_dom       
IPR035542   CRIP       
IPR012677   Nucleotide-bd_a/b_plait_sf       
SUPFAM
SSF54928   SSF54928        + More
SSF50891   SSF50891       
Gene 3D
PDB
6QDV     E-value=3.31614e-25,     Score=288

Ontologies

Topology

Subcellular location
Nucleus  
Length:
683
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.97504
Exp number, first 60 AAs:
0.00396
Total prob of N-in:
0.04492
outside
1  -  683
 
 

Population Genetic Test Statistics

Pi
241.846919
Theta
193.513458
Tajima's D
0.703118
CLR
0.003402
CSRT
0.573821308934553
Interpretation
Uncertain
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