Gene

KWMTBOMO01383  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008904

Annotation

PREDICTED:_polypeptide_N-acetylgalactosaminyltransferase_5_[Amyelois_transitella]

Location

Bomo_Chr3(+):9349481-9363587      View in EpiBrowser

Full name

Polypeptide N-acetylgalactosaminyltransferase       + More
Polypeptide N-acetylgalactosaminyltransferase 5      

Alternative Name

Protein-UDP acetylgalactosaminyltransferase
Protein-UDP acetylgalactosaminyltransferase 5
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5

Location in the cell

Nuclear   Reliability : 1.884

CDS

ATGTTCCGAAGTAAAATAAGGATTCACACGTGTCGTATTATCCTGCTGACGTCCTTGGCTTGGTTACTGGTGGACGTTATGCTGCTGGCTATGTATTCGGACTGCTTCGGCGACGGATGTAATCAGAAGACTGTTACTAGTGAAATTTCAATTGGGAAGGAGGCATACAAAGGGAAAAAAGCAGCAATTGCTGCAGCACTTCAACAGGATGTAGGTGATGATGATACAAATTTAGAAGAGAATGTATTGGGCCAAGAGGTTGAGGATGATGGGGTTTTATTATCTCCATATCCAAGGTCAAGACTCAAAAGGTGGCAGCGAGCACCTTCTGTGATACCCCAGGGAGAATCACCTGGTGAAATGGGTAAGGCTGTGAACATTCCGATTGAGCAGGAGAAGTTGATGTTAGATAAATTCCAAGAGAACCAATTCAATCTTTTGGCCAGCGATATGATCTCACTCAACAGGTCACTGACCGACGTCAGATTCGAAAAATGCAAGGACAAGCAATATCCAGAGTTGATGCCAACGACGAGCGTAGTTATAGTGTTCCACAACGAGGCCTGGTCGACTCTAATCAGAACTATATGGAGCACGATAAACAGGTCGCCGAAAGCTCTGCTCAAAGAAATTATTCTCGTTGATGACGCTAGTGAAAAAGGTGAGATTTTATATTACATTAAACGAATCTTTGTGCTTAGTAACAAAGTAAAAATATAA

Protein

MFRSKIRIHTCRIILLTSLAWLLVDVMLLAMYSDCFGDGCNQKTVTSEISIGKEAYKGKKAAIAAALQQDVGDDDTNLEENVLGQEVEDDGVLLSPYPRSRLKRWQRAPSVIPQGESPGEMGKAVNIPIEQEKLMLDKFQENQFNLLASDMISLNRSLTDVRFEKCKDKQYPELMPTTSVVIVFHNEAWSTLIRTIWSTINRSPKALLKEIILVDDASEKGEILYYIKRIFVLSNKVKI

Catalytic Activity

L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP
L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP

Cofactor

Mn(2+)

Similarity

Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.

Keywords

Alternative splicing   Complete proteome   Disulfide bond   Glycoprotein   Glycosyltransferase   Golgi apparatus   Lectin   Manganese   Membrane   Metal-binding   Reference proteome   Signal-anchor   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Polypeptide N-acetylgalactosaminyltransferase
splice variant  In isoform B.

Uniprot

H9JHA7   A0A2W1BJC4   A0A2H1V243   A0A2A4K9S6   A0A194Q3I0   A0A194RMQ9   + More
A0A212FDU4   A0A0L7LHX6   A0A2J7RBS8   D6WVN2   A0A067RJP5   A0A2J7RBV9   A0A1B6E0T5   A0A1B6BW91   N6TS93   U4U5M5   K7J3H1   T1E2I9   A0A1Q3F0J8   A0A1Q3F100   A0A2R7W5H1   A0A0N8NZB4   B3MPA0   A0A0R3NSQ1   A0A1A9X5T5   A0A1W4UIP5   A0A1A9UTB8   A0A2M4DRZ9   A0A3B0JIK5   A0A1A9Z0D8   A0A0P5DED9   A0A2H8U044   A0A1B0FQB6   A0A3B0JJ34   A0A0P5AT39   A0A1L8E279   A0A1A9YL93   E9HLY2   B4I1D1   A0A0J9QX07   A0A0R1DMM4   Q6WV17   Q6WV17-2   A0A0J9QW36   B4P3T1   A0A0P5HTX4   B3N4S7   A0A0Q5W9B4   A0A2M4CS93   A0A0P6CV18   A0A0P6FLL2   A0A146LCQ1   A0A0P5ESM3   A0A0P5ZIC8   A0A0N8AGY1   A0A0P5EKM4   A0A2S2NUP5   J9JLD8   A0A1S4GYR0   A0A1S4GZG0   A0A0N7ZEP6   A0A0Q9XAP7   T1HS15   A0A3B0JMZ1   B4KGT0   A0A0A9Z0W6   A0A3B0JPF7   B4MU14   A0A0Q9WYQ5   A0A0P4YNL2   B4LUF2   A0A0Q9WKK0   Q29MW2   A0A1W4UVZ0   A0A0R3NS93   B4G8M8   A0A1W4UVP4   A0A2M4BGJ7   A0A0P4VU64   A0A0N8AUT9   A0A0P5IXN2   A0A0P5PID6   A0A0P5DTH6   A0A0P4VRH7   B4JAT3   A0A023F5E7   T1P8U2   A0A1I8PFH5   A0A0P5RHG6   A0A0P6DC98   A0A0N8BND7   A0A0P5Z058   A0A1I8PFR7   A0A0L0C8W7   A0A0P6D2A0   A0A1Y1NCE0   A0A0M4E8C9   A0A2S2QI64   E2BM83   A0A0P6B0Q2  

EC Number

2.4.1.-
2.4.1.41

Pubmed

19121390    28756777    26354079    22118469    26227816    18362917    + More
19820115    24845553    23537049    20075255    24330624    17994087    18057021    15632085    21292972    22936249    17550304    10731132    12537572    12537569    12829714    16251381    26823975    12364791    25401762    27129103    25474469    26108605    28004739    20798317   

EMBL

BABH01012584    KZ150259    PZC71763.1    ODYU01000332    SOQ34901.1    NWSH01000002    + More
PCG81045.1    KQ459562    KPI99913.1    KQ459989    KPJ18709.1    AGBW02009016    OWR51857.1    JTDY01001050    KOB75010.1    NEVH01005890    PNF38297.1    KQ971357    EFA08271.1    KK852639    KDR19630.1    PNF38298.1    GEDC01026756    GEDC01005777    JAS10542.1    JAS31521.1    GEDC01031747    GEDC01000495    JAS05551.1    JAS36803.1    APGK01056897    KB741277    ENN71186.1    KB632155    ERL89204.1    GALA01001220    JAA93632.1    GFDL01013962    JAV21083.1    GFDL01013815    JAV21230.1    KK854231    PTY13455.1    CH902620    KPU73852.1    EDV32219.2    CH379060    KRT03964.1    GGFL01016146    MBW80324.1    OUUW01000006    SPP82244.1    GDIP01158735    JAJ64667.1    GFXV01007725    MBW19530.1    CCAG010009728    SPP82245.1    GDIP01194778    JAJ28624.1    GFDF01001310    JAV12774.1    GL732682    EFX67256.1    CH480820    EDW54338.1    CM002910    KMY88254.1    CM000157    KRJ97741.1    AE014134    AY060338    AY268066    KMY88253.1    EDW88382.2    GDIQ01222998    JAK28727.1    CH954177    EDV57829.1    KQS70160.1    GGFL01003971    MBW68149.1    GDIQ01087339    JAN07398.1    GDIQ01047709    JAN47028.1    GDHC01014303    GDHC01012638    GDHC01000315    JAQ04326.1    JAQ05991.1    JAQ18314.1    GDIQ01270753    JAJ80971.1    GDIP01043553    JAM60162.1    GDIP01148489    GDIQ01047708    JAJ74913.1    JAN47029.1    GDIQ01270752    JAJ80972.1    GGMR01008169    MBY20788.1    ABLF02017877    AAAB01008944    GDIP01252769    JAI70632.1    CH933807    KRG02538.1    ACPB03021813    SPP82243.1    EDW11130.1    GBHO01006098    GBHO01000992    JAG37506.1    JAG42612.1    SPP82242.1    CH963852    EDW75603.2    KRF98280.1    GDIP01235132    JAI88269.1    CH940649    EDW64138.2    KRF81438.1    EAL33581.1    KRT03963.1    CH479180    EDW28708.1    GGFJ01003011    MBW52152.1    GDKW01000397    JAI56198.1    GDIQ01240747    JAK10978.1    GDIQ01206153    JAK45572.1    GDIQ01133634    JAL18092.1    GDIP01152981    JAJ70421.1    GDRN01104804    JAI57854.1    CH916368    EDW03891.1    GBBI01002354    JAC16358.1    KA645196    AFP59825.1    GDIQ01105886    JAL45840.1    GDIP01131747    GDIQ01081047    JAL71967.1    JAN13690.1    GDIQ01160763    LRGB01002674    JAK90962.1    KZS06591.1    GDIP01052051    JAM51664.1    JRES01000753    KNC28682.1    GDIQ01083987    JAN10750.1    GEZM01010699    JAV93896.1    CP012523    ALC38238.1    GGMS01008211    MBY77414.1    GL449158    EFN83209.1    GDIP01021816    JAM81899.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000037510    + More
UP000235965    UP000007266    UP000027135    UP000019118    UP000030742    UP000002358    UP000007801    UP000001819    UP000091820    UP000192221    UP000078200    UP000268350    UP000092445    UP000092444    UP000092443    UP000000305    UP000001292    UP000002282    UP000000803    UP000008711    UP000007819    UP000009192    UP000015103    UP000007798    UP000008792    UP000008744    UP000001070    UP000095300    UP000076858    UP000037069    UP000092553    UP000008237   

PRIDE

H9JHA7    Q6WV17   

Pfam

PF00652   Ricin_B_lectin        + More
PF00535   Glycos_transf_2
PF02709   Glyco_transf_7C

Interpro

IPR029044   Nucleotide-diphossugar_trans        + More
IPR001173   Glyco_trans_2-like       
IPR035992   Ricin_B-like_lectins       
IPR000772   Ricin_B_lectin       
IPR027791   Galactosyl_T_C       

SUPFAM

SSF50370   SSF50370        + More
SSF53448   SSF53448       

Gene 3D

3.90.550.10    

CDD

cd00161  RICIN

ProteinModelPortal

H9JHA7   A0A2W1BJC4   A0A2H1V243   A0A2A4K9S6   A0A194Q3I0   A0A194RMQ9   + More
A0A212FDU4   A0A0L7LHX6   A0A2J7RBS8   D6WVN2   A0A067RJP5   A0A2J7RBV9   A0A1B6E0T5   A0A1B6BW91   N6TS93   U4U5M5   K7J3H1   T1E2I9   A0A1Q3F0J8   A0A1Q3F100   A0A2R7W5H1   A0A0N8NZB4   B3MPA0   A0A0R3NSQ1   A0A1A9X5T5   A0A1W4UIP5   A0A1A9UTB8   A0A2M4DRZ9   A0A3B0JIK5   A0A1A9Z0D8   A0A0P5DED9   A0A2H8U044   A0A1B0FQB6   A0A3B0JJ34   A0A0P5AT39   A0A1L8E279   A0A1A9YL93   E9HLY2   B4I1D1   A0A0J9QX07   A0A0R1DMM4   Q6WV17   Q6WV17-2   A0A0J9QW36   B4P3T1   A0A0P5HTX4   B3N4S7   A0A0Q5W9B4   A0A2M4CS93   A0A0P6CV18   A0A0P6FLL2   A0A146LCQ1   A0A0P5ESM3   A0A0P5ZIC8   A0A0N8AGY1   A0A0P5EKM4   A0A2S2NUP5   J9JLD8   A0A1S4GYR0   A0A1S4GZG0   A0A0N7ZEP6   A0A0Q9XAP7   T1HS15   A0A3B0JMZ1   B4KGT0   A0A0A9Z0W6   A0A3B0JPF7   B4MU14   A0A0Q9WYQ5   A0A0P4YNL2   B4LUF2   A0A0Q9WKK0   Q29MW2   A0A1W4UVZ0   A0A0R3NS93   B4G8M8   A0A1W4UVP4   A0A2M4BGJ7   A0A0P4VU64   A0A0N8AUT9   A0A0P5IXN2   A0A0P5PID6   A0A0P5DTH6   A0A0P4VRH7   B4JAT3   A0A023F5E7   T1P8U2   A0A1I8PFH5   A0A0P5RHG6   A0A0P6DC98   A0A0N8BND7   A0A0P5Z058   A0A1I8PFR7   A0A0L0C8W7   A0A0P6D2A0   A0A1Y1NCE0   A0A0M4E8C9   A0A2S2QI64   E2BM83   A0A0P6B0Q2  

PDB

1XHB     E-value=1.17248e-25,     Score=286

KEGG

101744145    K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] | (RefSeq) polypeptide N-acetylga

GO

GO:0000139   GO:0016021   GO:0030246   GO:0016757   GO:0006486   GO:0016740   GO:0005794   GO:0009312   GO:0004653   GO:0005795   GO:0012505   GO:0046872  

Subcellular location

Golgi apparatus membrane  

Length:

239

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.85389

Exp number, first 60 AAs:

19.79419

Total prob of N-in:

0.98246

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  32

outside

33  -  239

 

 

Pi

206.114614

Theta

188.993917

Tajima's D

0.413073

CLR

0.260224

CSRT

0.488425578721064

Interpretation

Uncertain