SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01365
Pre Gene Modal
BGIBMGA008898
Annotation
PREDICTED:_ATP-dependent_DNA_helicase_PIF1_isoform_X2_[Papilio_xuthus]
Full name
ATP-dependent DNA helicase PIF1       + More
ATP-dependent DNA helicase      
Alternative Name
DNA repair and recombination helicase PIF1
Location in the cell
Mitochondrial   Reliability : 3.238
 

Sequence

CDS
ATGTTTTTAGAAGTGACATCCGAAAAACATGCCGCCACTAAATTGGCTCTTAAAAGTTTCAATGTTTTCAAAAAGTTTATGGCTGAAGGTAAAGCAAGTATTAAGTTCCAGGAAGCTAATTGTACAATATTTATTTCAAATGCACCTCCTACAAATTTGGTAATGTTTCTTCGAACTATATTTGTTAAGATGACCAGTGATGAAGAGCAAAAAGCAAATAAAACTCCATCAAAACAGTCAATGAGGGCAAAGCTGTTAAGTGGTAAATCCCAATCATTTGATGAAATAAGTCCAGTTACAGTTGCCGACATTCATATTGCGAAAAGTAAAATTTCAAAATCTACAATCACAACACCATCACCGCCTTCAAAGAAACGAACAGGAAAAAGTTTCTTATTAAAAAGGATTGTGGCAGCTCTACCTCCTGATGTAACGATGCCCACTGCATCCACTGGTGTCGCAGCTTGTCACATTGGTGGTACCACTCTTCATGCTTTTGCTGGCATAGGTGATGGTAGTGGGTCTATCGAAAATTTATGTGAAAGAGCTACTAAAATACCATTGGTAGCACAAAAATGGAGAAAATGTAAACACCTTATTATAGATGAGATATCAATGGTCGATGGAATATTTTTTGAGGTACATAGACAAACAGATCAAGAATTTATTTCGATTCTCAATAGTATCAGAATTGGTCGTGTTACTAAAGAAATCAGCAACAGATTAACAAGAACAGCAAGGCAGAAAATTGAGGCTGATGGCATTTTAGCAACTAGATTATGCTCACATACTAATGACTCAAAAATGATAAATGAGTCAAAATTGATAGCTTTGGATGGAGAGGGAAAATTATTTACATCACAAGACAGTGATAATGCTACTACATTACTAGATATGCAAACTATTGCCCCTTCTAAACTCATGTTAAAAATTGGAGCACAAGTAATGTTATTAAAAAATATTAATGTAAATTCAGGTTTAGTTAATGGAGCCAGAGGAATTGTTGTTCGATTTGAAGAAGGATTCCCTGTTGTTAGATTTAAAAACAAAAAAGAATACATAGCCAGAACAGAACGCTGGTATGTCAAAAATTCGAATGGTACATTATTATGTCGCAGGCAAGTTCCGTTGTCTTTAGCGTGGGCTTTTTCAATACATAAGTCACAAGGATTAACTTTAGACTGTGTTGAGATGTCACTGTCGAAAATATTTGAAGCTGGACAAGCTTATGTTGCATTGAGTAGAGCACAAAGCTTAGACAGCCTTCGTGTATTAGATTTTGATTCCAGACATGTATGGGCAAACCCTGATGTTCTAGAATTTTATCAAAGATTCAGACGAAGATTGCAACAAATGGAGATAGTACCACTTGGTAGACCATTACCTGAAAAAGCAACTAAGAAGTTGAAACTTAGAGATATTTTAGAGAAGCAATTAAGACAGAAATAG
Protein
MFLEVTSEKHAATKLALKSFNVFKKFMAEGKASIKFQEANCTIFISNAPPTNLVMFLRTIFVKMTSDEEQKANKTPSKQSMRAKLLSGKSQSFDEISPVTVADIHIAKSKISKSTITTPSPPSKKRTGKSFLLKRIVAALPPDVTMPTASTGVAACHIGGTTLHAFAGIGDGSGSIENLCERATKIPLVAQKWRKCKHLIIDEISMVDGIFFEVHRQTDQEFISILNSIRIGRVTKEISNRLTRTARQKIEADGILATRLCSHTNDSKMINESKLIALDGEGKLFTSQDSDNATTLLDMQTIAPSKLMLKIGAQVMLLKNINVNSGLVNGARGIVVRFEEGFPVVRFKNKKEYIARTERWYVKNSNGTLLCRRQVPLSLAWAFSIHKSQGLTLDCVEMSLSKIFEAGQAYVALSRAQSLDSLRVLDFDSRHVWANPDVLEFYQRFRRRLQQMEIVPLGRPLPEKATKKLKLRDILEKQLRQK

Summary

Description
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Cofactor
Mg(2+)
Subunit
Monomer.
Similarity
Belongs to the helicase family. PIF1 subfamily.
Belongs to the helicase family.
EC Number
3.6.4.12
Pfam
PF08626   TRAPPC9-Trs120        + More
PF05970   PIF1
PF02689   Herpes_Helicase
Interpro
IPR003593   AAA+_ATPase        + More
IPR010285   DNA_helicase_pif1-like       
IPR013935   TRAPP_II_complex_Trs120       
IPR027417   P-loop_NTPase       
IPR003840   DNA_helicase       
SUPFAM
SSF52540   SSF52540       
PDB
5FHH     E-value=3.21987e-76,     Score=726

Ontologies

Topology

Subcellular location
Nucleus  
Mitochondrion  
Length:
482
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.11683
Exp number, first 60 AAs:
0.09751
Total prob of N-in:
0.00736
outside
1  -  482
 
 

Population Genetic Test Statistics

Pi
253.837075
Theta
199.703053
Tajima's D
0.848831
CLR
0
CSRT
0.613769311534423
Interpretation
Uncertain
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