Gene

KWMTBOMO01350  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008999

Annotation

PREDICTED:_probable_serine/threonine-protein_kinase_nek3_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr3(-):8420770-8446446      View in EpiBrowser

Full name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial       + More
Zinc finger C2HC domain-containing protein 1A      

Transcription factor

zf-C2H2

Location in the cell

Nuclear   Reliability : 4.18

CDS

ATGCCTTGTCTTGTCTGCGGACGTACTTTTGTGCCACAGTCTCTAGCTAAGCACGTCAAGATTTGCGAGAAGATGACTATTAAAAAACGGAAGACTTTTGATTCCTCAAGACAGAGACGAGAAGGTACAGATTTAGAACAATACTTGCCAAAGAACTTCGGTCTTCCAGAAAACAGTCCATTCCTCGAGAAGAGTCCCCCGCCCACTGCCAAACCCACATTGAAACCTAAACCGCAATCGGTCCGCAGTGCCATAACAAAGCCAATGGCAGAACTGCAGAAGTGTCCGCACTGCGGCCGAGCGTTCGGCGTTCGTGCTTTCGAGAGGCACGTGGAGTGGTGCGCGGACAAGGCCAAGATCTTGCCGGCCGCGCCCGCACACCCGCCGCCGCACATCGCCGACGCCAAGCAGAGACTGAACGCGCGAACACAGTACAAAGCACCCCTGGCTCGAGGTAGAAAAACGTCTCAGTCACGTGACAAATCGTCGAACAGTCGTTCAACGTCTGTAGATTCGTCTCGAGGAGTCTCTCCGCCGCCTCCGCGTGACTGCGGCGACTATGGTGCTGCTAGATCAAGAGCCTCTGGTAATATACACATTCTAAGCTACAAGTATAGATTTAAATCGTTTTAA

Protein

MPCLVCGRTFVPQSLAKHVKICEKMTIKKRKTFDSSRQRREGTDLEQYLPKNFGLPENSPFLEKSPPPTAKPTLKPKPQSVRSAITKPMAELQKCPHCGRAFGVRAFERHVEWCADKAKILPAAPAHPPPHIADAKQRLNARTQYKAPLARGRKTSQSRDKSSNSRSTSVDSSRGVSPPPPRDCGDYGAARSRASGNIHILSYKYRFKSF

Description

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic Activity

a quinone + succinate = a quinol + fumarate

Cofactor

FAD

Similarity

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Belongs to the ZC2HC1 family.

Keywords

Metal-binding   Zinc   Zinc-finger  

Feature

chain  Zinc finger C2HC domain-containing protein 1A

Uniprot

A0A2W1C3Y9   A0A1E1WGN1   A0A2H1VE35   A0A0L7LIU5   A0A194PU74   A0A194RRQ4   + More
A0A182W3S1   A0A182SRD6   A0A182FM27   A0A1B0GKR0   A0A182QM42   A0A1S4HDJ5   A0A182NDK3   A0A182V4R6   A0A182HX86   A0A182WRA0   A0A182JU35   A0A182RBD8   A0A2M4CLF4   A0A084VTQ8   A0A182MS36   A0A182PK86   A0A182JL81   A0A182YLX5   A0A1B6E157   A0A0C9RA44   A0A0C9QJI9   A0A067QQ78   A0A1B6K5C5   A0A336MIL1   A0A336KCQ2   A0A336LYU4   A0A2A3E9N4   A0A139WDG4   A0A139WDK2   A0A2R7WWS9   E9IMU8   A0A0L7QPJ1   A0A0J7L7M0   A0A088A6T2   A0A0A9WBF7   A0A146L0C1   E2B4M4   A0A2S2QE18   E2AFW4   A0A1B6JC03   A0A1B6FMR8   A0A1B6G0I1   A0A195D1B2   J9LI08   J9KNH2   A0A1B6L418   A0A1B6KU29   A0A210QMU4   Q5PPV5   A0A1L8FTC2   A0A131YKW5   E9H118   L7M2A2   A0A099YW95   G1LMV0  

EC Number

1.3.5.1

Pubmed

28756777    26227816    26354079    12364791    24438588    25244985    + More
24845553    18362917    19820115    21282665    25401762    26823975    20798317    28812685    27762356    26830274    21292972    25576852    20010809   

EMBL

KZ149894    PZC78883.1    GDQN01004891    JAT86163.1    ODYU01002049    SOQ39077.1    + More
JTDY01000907    KOB75483.1    KQ459591    KPI96961.1    KQ459989    KPJ18736.1    AJWK01030933    AJWK01030934    AJWK01030935    AJWK01030936    AJWK01030937    AJWK01030938    AXCN02001758    AAAB01008849    APCN01005154    GGFL01001907    MBW66085.1    ATLV01016450    KE525091    KFB41352.1    AXCM01000169    GEDC01005649    JAS31649.1    GBYB01003686    JAG73453.1    GBYB01003689    JAG73456.1    KK853598    KDR06405.1    GECU01001045    JAT06662.1    UFQS01001264    UFQT01001264    SSX10048.1    SSX29770.1    UFQS01000218    UFQT01000218    SSX01508.1    SSX21888.1    SSX01509.1    SSX21889.1    KZ288312    PBC28435.1    KQ971358    KYB25983.1    KYB25982.1    KK855824    PTY24004.1    GL764255    EFZ18090.1    KQ414819    KOC60474.1    LBMM01000341    KMR00218.1    GBHO01041431    GBHO01041430    GBHO01041429    GDHC01008056    JAG02173.1    JAG02174.1    JAG02175.1    JAQ10573.1    GDHC01017927    JAQ00702.1    GL445574    EFN89377.1    GGMS01006781    MBY75984.1    GL439166    EFN67671.1    GECU01010940    JAS96766.1    GECZ01018273    JAS51496.1    GECZ01013825    JAS55944.1    KQ976973    KYN06700.1    ABLF02020928    ABLF02020932    GEBQ01021592    JAT18385.1    GEBQ01025027    JAT14950.1    NEDP02002776    OWF50052.1    BC087481    CM004477    OCT74830.1    GEDV01008614    JAP79943.1    GL732582    EFX74602.1    GACK01007810    JAA57224.1    KL885833    KGL73223.1    ACTA01100546    ACTA01108546    ACTA01116546    ACTA01124546    ACTA01132546    ACTA01140546    ACTA01148545   

Proteomes

UP000037510    UP000053268    UP000053240    UP000075920    UP000075901    UP000069272    + More
UP000092461    UP000075886    UP000075884    UP000075903    UP000075840    UP000076407    UP000075881    UP000075900    UP000030765    UP000075883    UP000075885    UP000075880    UP000076408    UP000027135    UP000242457    UP000007266    UP000053825    UP000036403    UP000005203    UP000008237    UP000000311    UP000078542    UP000007819    UP000242188    UP000186698    UP000000305    UP000053641    UP000008912   

PRIDE

Q5PPV5   

Pfam

PF00378   ECH_1        + More
PF02910   Succ_DH_flav_C
PF00890   FAD_binding_2

Interpro

IPR026319   ZC2HC1        + More
IPR001753   Enoyl-CoA_hydra/iso       
IPR029045   ClpP/crotonase-like_dom_sf       
IPR014748   Enoyl-CoA_hydra_C       
IPR026104   ZNF_C2HC_dom_1C       
IPR003953   FAD-binding_2       
IPR015939   Fum_Rdtase/Succ_DH_flav-like_C       
IPR014006   Succ_Dhase_FrdA_Gneg       
IPR027477   Succ_DH/fumarate_Rdtase_cat_sf       
IPR011281   Succ_DH_flav_su_fwd       
IPR036188   FAD/NAD-bd_sf       
IPR037099   Fum_R/Succ_DH_flav-like_C_sf       
IPR003952   FRD_SDH_FAD_BS       

SUPFAM

SSF52096   SSF52096        + More
SSF56425   SSF56425       
SSF46977   SSF46977       
SSF51905   SSF51905       

Gene 3D

1.10.12.10     3.50.50.60     3.90.700.10    

ProteinModelPortal

A0A2W1C3Y9   A0A1E1WGN1   A0A2H1VE35   A0A0L7LIU5   A0A194PU74   A0A194RRQ4   + More
A0A182W3S1   A0A182SRD6   A0A182FM27   A0A1B0GKR0   A0A182QM42   A0A1S4HDJ5   A0A182NDK3   A0A182V4R6   A0A182HX86   A0A182WRA0   A0A182JU35   A0A182RBD8   A0A2M4CLF4   A0A084VTQ8   A0A182MS36   A0A182PK86   A0A182JL81   A0A182YLX5   A0A1B6E157   A0A0C9RA44   A0A0C9QJI9   A0A067QQ78   A0A1B6K5C5   A0A336MIL1   A0A336KCQ2   A0A336LYU4   A0A2A3E9N4   A0A139WDG4   A0A139WDK2   A0A2R7WWS9   E9IMU8   A0A0L7QPJ1   A0A0J7L7M0   A0A088A6T2   A0A0A9WBF7   A0A146L0C1   E2B4M4   A0A2S2QE18   E2AFW4   A0A1B6JC03   A0A1B6FMR8   A0A1B6G0I1   A0A195D1B2   J9LI08   J9KNH2   A0A1B6L418   A0A1B6KU29   A0A210QMU4   Q5PPV5   A0A1L8FTC2   A0A131YKW5   E9H118   L7M2A2   A0A099YW95   G1LMV0  

KEGG

101735348    no KO assigned | (RefSeq) homeobox protein 5

GO

GO:0003824   GO:0050660   GO:0006099   GO:0022900   GO:0005743   GO:0008177   GO:0016491   GO:0046872  

PANTHER

PTHR13555   PTHR14649  

Subcellular location

Mitochondrion inner membrane  

Length:

210

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00018

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.06768

outside

1  -  210

 

 

Pi

272.032378

Theta

175.282756

Tajima's D

1.136754

CLR

0.349479

CSRT

0.699265036748163

Interpretation

Uncertain