Gene

KWMTBOMO01321

Pre Gene Modal

BGIBMGA008882

Annotation

Coiled-coil_domain-containing_protein_164_[Papilio_xuthus]

Location

Bomo_Chr3(+):7990405-7991856      View in EpiBrowser

Full name

Dynein regulatory complex protein 1      

Alternative Name

Coiled-coil domain-containing protein 164

Location in the cell

Cytoplasmic   Reliability : 1.901 Nuclear   Reliability : 2.006

CDS

ATGGCTGGAACTTTCGAAAGATATAATGACGAAGAAGACGATGTCCTCGCTCCTACAGAACCTCAAATTACGTCACATGACCCAGTCGAGAGAAAAGCAGCTAGGTCTCTTCGTATCAAAAGGAGACAAGAAGCGTTAAAAAGATCAGAACAACAAACTGAAGAAATCGTAGCAGATGAAGATGCTGGTCCAATAGAACTAGCTACAGCTACCGCTGCAGAGGAGTTGCAGAGGTTGAATCTTGATGGAGCTGCTAAAGTTACCAATGTCAAAGTCACCACCGACGAACGAGAGGTCTTAAGAAGAGGATTATTCGCAGATAATATGAGAGATTTGATGAAGAAGATAGAAGACGAAGCAACAGAGGCGCAGATCCAGTATGAAGCTATTACGTCAAATTGGAATACCATGCTCAATATCAAAGATCCATTAGATATAGACGCAGAAATGAAAAAGCAGAGACAAAAATGCGATTTCTTAATGGAACAAAAAAATGAAGTGATAACTGAATTAAAGAATAACCTACAACAAATGGATGATGCTTATTATGAAGACTTAGATAAACAAGATAAAGATATCAAAGAATTGTCTGATAGAATCGAAAAACAAGTAACTATAATGCAAAGAGCTTATGAAAAACAACTATCCTTGATAGAACAAGCGATAAAAATCGAGCGGGAAGTTATGGTTGATCACAACAATAAGCGTTGGGAAGCTCTCTACAAGCAACGTGACAAAGAAGAATTAGCTCATATGGAATATAGATCAAAGCAGGTAGTACCCTACATTAATGAATAG

Protein

MAGTFERYNDEEDDVLAPTEPQITSHDPVERKAARSLRIKRRQEALKRSEQQTEEIVADEDAGPIELATATAAEELQRLNLDGAAKVTNVKVTTDEREVLRRGLFADNMRDLMKKIEDEATEAQIQYEAITSNWNTMLNIKDPLDIDAEMKKQRQKCDFLMEQKNEVITELKNNLQQMDDAYYEDLDKQDKDIKELSDRIEKQVTIMQRAYEKQLSLIEQAIKIEREVMVDHNNKRWEALYKQRDKEELAHMEYRSKQVVPYINE

Description

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.

Subunit

Component of the nexin-dynein regulatory complex (N-DRC).

Similarity

Belongs to the DRC1 family.

Keywords

Cell projection   Cilium   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Flagellum   Reference proteome   Alternative splicing  

Feature

chain  Dynein regulatory complex protein 1
splice variant  In isoform 2.

Uniprot

H9JH85   A0A194Q0P9   A0A212EQ90   A0A194RLP4   A0A2A4JWG6   A0A2H1V4W7   + More
A0A2W1BB13   A0A0L7KW19   E2A978   K7IRP6   N6TCB0   A0A1B6E7F5   D6WW89   A0A1B6H2U9   A0A2P8YZ81   A0A1W4X557   A0A195C5I2   A0A0T6B4Y0   A0A067R106   A0A1B6HY05   A0A1B6JYY2   A0A195ELQ5   A0A151XK50   A0A195B692   A0A195FQQ7   A0A158NRG2   A0A0N0U790   A0A026WS03   A0A3L8DE78   A0A3B4CJN6   F4WCD3   M3XKW7   U4TRU7   A0A2A3E9K3   E2RNF2   U6CPM0   H3BBN8   R7US70   B3S1I6   A0A088A6V4   A0A3Q0CXB7   A0A2K6V6V6   A0A2K5BY58   A0A1S3EYK5   A0A1S3J526   A0A2Y9K7C5   A0A369SCZ1   A0A2K6RXB2   G3VJS1   A0A2K6LRY3   A0A2U3VJA5   A0A3Q0EBM9   A0A1U7U8B4   G3VJS0   Q5XI65   A0A384AW54   A0A384AVB4   A0A2Y9DN52   A0A2K5HT22   A0A2Y9HUQ2   A0A0D9R8U0   L5KTC3   F7I4J7   A0A2U3XN83   D2GXN6   G1L657   A0A2K5PWQ6   Q32KY1   F7I4K2   G1PFA5   A0A1S3AC10   H0WS42   G3SPF8   A0A3B3IT12   A0A336MHQ0   A0A336LPQ8   A0A287DG81   I3LYY9   A0A2K5NS29   A0A2K5NS92   W5QBW2   Q95JM8-2   A0A2K6EW45   Q95JM8   F1SDN3   A0A286ZTR0   A0A0L8I593   A0A2Y9NKZ6   F6V1X1   A0A096NR04   A0A1W2WPJ5  

Pubmed

19121390    26354079    22118469    28756777    26227816    20798317    + More
20075255    23537049    18362917    19820115    29403074    24845553    21347285    24508170    30249741    21719571    9215903    16341006    23254933    18719581    26319212    30042472    25362486    21709235    15489334    23258410    20010809    16305752    25243066    21993624    15815621    20809919    12498619    22002653    11574149    19892987   

EMBL

BABH01012762    BABH01012763    BABH01012764    KQ459591    KPI96985.1    AGBW02013301    + More
OWR43634.1    KQ459989    KPJ18758.1    NWSH01000444    PCG76367.1    ODYU01000688    SOQ35881.1    KZ150536    PZC70587.1    JTDY01005146    KOB67325.1    GL437711    EFN70063.1    APGK01035752    KB740928    ENN77944.1    GEDC01026120    GEDC01024712    GEDC01003438    JAS11178.1    JAS12586.1    JAS33860.1    KQ971361    EFA08677.1    GECZ01000792    JAS68977.1    PYGN01000274    PSN49548.1    KQ978292    KYM95441.1    LJIG01009875    KRT82206.1    KK853016    KDR12480.1    GECU01028163    JAS79543.1    GECU01003583    JAT04124.1    KQ978739    KYN28809.1    KQ982052    KYQ60658.1    KQ976582    KYM79775.1    KQ981305    KYN42803.1    ADTU01001963    ADTU01001964    KQ435709    KOX80024.1    KK107119    EZA58830.1    QOIP01000009    RLU18218.1    GL888070    EGI68113.1    AFYH01030224    AFYH01030225    AFYH01030226    AFYH01030227    AFYH01030228    KB630163    KB630856    KB631023    ERL83442.1    ERL83906.1    ERL84013.1    KZ288312    PBC28405.1    AAEX03010794    AAEX03010795    HAAF01000709    CCP72535.1    AMQN01006549    KB298648    ELU08983.1    DS985247    EDV23550.1    NOWV01000022    RDD44726.1    AEFK01151971    AEFK01151972    BC083825    AQIB01033533    AQIB01033534    AQIB01033535    AQIB01033536    AQIB01033537    AQIB01033538    AQIB01033539    AQIB01033540    AQIB01033541    AQIB01033542    KB030580    ELK14048.1    GL192369    EFB20555.1    ACTA01136640    ACTA01144639    ACTA01152638    BT026555    BC109861    GAMS01007488    JAB15648.1    AAPE02039328    AAQR03049280    AAQR03049281    AAQR03049282    AAQR03049283    AAQR03049284    AC010896    AC093378    KF459613    UFQS01001310    UFQT01001310    SSX10254.1    SSX29942.1    UFQS01000044    UFQT01000044    SSW98415.1    SSX18801.1    AGTP01025124    AGTP01025125    AMGL01075834    AMGL01075835    AMGL01075836    AMGL01075837    AMGL01075838    AMGL01075839    AMGL01075840    AB070022    AB070128    AB070153    AB070161    AB070184    CM001288    AB046103    AEMK02000021    KQ416616    KOF96220.1    AHZZ02005076   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000218220    UP000037510    + More
UP000000311    UP000002358    UP000019118    UP000007266    UP000245037    UP000192223    UP000078542    UP000027135    UP000078492    UP000075809    UP000078540    UP000078541    UP000005205    UP000053105    UP000053097    UP000279307    UP000261440    UP000007755    UP000008672    UP000030742    UP000242457    UP000002254    UP000014760    UP000009022    UP000005203    UP000189706    UP000233220    UP000233020    UP000081671    UP000085678    UP000248482    UP000253843    UP000233200    UP000007648    UP000233180    UP000245340    UP000189704    UP000002494    UP000261681    UP000248480    UP000233080    UP000248481    UP000029965    UP000010552    UP000008225    UP000245341    UP000008912    UP000233040    UP000009136    UP000001074    UP000079721    UP000005225    UP000007646    UP000005640    UP000005215    UP000233060    UP000002356    UP000009130    UP000233100    UP000233160    UP000008227    UP000053454    UP000248483    UP000002281    UP000028761   

PRIDE

H9JH85    Q5XI65    Q32KY1    Q95JM8    F1SDN3   

Pfam

PF14775   NYD-SP28_assoc        + More
PF04750   Far-17a_AIG1
PF14772   NYD-SP28
PF00096   zf-C2H2

Interpro

IPR006838   Far-17a_AIG1        + More
IPR039505   DRC1/2_N       
IPR029440   DRC1_C       
IPR039750   DRC1/DRC2       
IPR022803   Ribosomal_L5_dom_sf       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       

SUPFAM

SSF55282   SSF55282        + More
SSF57667   SSF57667       

Gene 3D

3.30.1440.10    

ProteinModelPortal

H9JH85   A0A194Q0P9   A0A212EQ90   A0A194RLP4   A0A2A4JWG6   A0A2H1V4W7   + More
A0A2W1BB13   A0A0L7KW19   E2A978   K7IRP6   N6TCB0   A0A1B6E7F5   D6WW89   A0A1B6H2U9   A0A2P8YZ81   A0A1W4X557   A0A195C5I2   A0A0T6B4Y0   A0A067R106   A0A1B6HY05   A0A1B6JYY2   A0A195ELQ5   A0A151XK50   A0A195B692   A0A195FQQ7   A0A158NRG2   A0A0N0U790   A0A026WS03   A0A3L8DE78   A0A3B4CJN6   F4WCD3   M3XKW7   U4TRU7   A0A2A3E9K3   E2RNF2   U6CPM0   H3BBN8   R7US70   B3S1I6   A0A088A6V4   A0A3Q0CXB7   A0A2K6V6V6   A0A2K5BY58   A0A1S3EYK5   A0A1S3J526   A0A2Y9K7C5   A0A369SCZ1   A0A2K6RXB2   G3VJS1   A0A2K6LRY3   A0A2U3VJA5   A0A3Q0EBM9   A0A1U7U8B4   G3VJS0   Q5XI65   A0A384AW54   A0A384AVB4   A0A2Y9DN52   A0A2K5HT22   A0A2Y9HUQ2   A0A0D9R8U0   L5KTC3   F7I4J7   A0A2U3XN83   D2GXN6   G1L657   A0A2K5PWQ6   Q32KY1   F7I4K2   G1PFA5   A0A1S3AC10   H0WS42   G3SPF8   A0A3B3IT12   A0A336MHQ0   A0A336LPQ8   A0A287DG81   I3LYY9   A0A2K5NS29   A0A2K5NS92   W5QBW2   Q95JM8-2   A0A2K6EW45   Q95JM8   F1SDN3   A0A286ZTR0   A0A0L8I593   A0A2Y9NKZ6   F6V1X1   A0A096NR04   A0A1W2WPJ5  

KEGG

101737654    K19754 dynein regulatry complex protein 1 | (RefSeq) dynein regulatory complex protein 1

GO

GO:0005858   GO:0016021   GO:0070286   GO:0005840   GO:0003352   GO:0060285   GO:0005930   GO:0003676   GO:0007507   GO:0007368   GO:0031514  

PANTHER

PTHR21625  

Subcellular location

Cytoplasm  
Cytoskeleton  
Cilium axoneme  
Flagellum axoneme  

Length:

265

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.06581

outside

1  -  265

 

 

Pi

66.884513

Theta

166.319281

Tajima's D

-0.525398

CLR

162.064321

CSRT

0.239538023098845

Interpretation

Uncertain