Gene

KWMTBOMO01281  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009018

Annotation

PREDICTED:_2-hydroxyphytanoyl-CoA_lyase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr3(-):7303559-7314498      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.476 Mitochondrial   Reliability : 1.654

CDS

ATGGGTATCGACGGAAATACAATCTTAGCTGAAAGTTTGAAGAAACAGGGTGTTGAATATGTATTTGGGATAGTTGGGATACCAGTCATTGAAACAGCAATGGCTTTCCAATCAGCTGGTCTAAAGTATATTGGTATGCGCAATGAACAAGCTGCCTGCTATGCTGCGCAAGCTACAGGCTATCTAACAGGTAAGCCAGGTGTTTGTTTAGTGGTATCAGGGCCGGGACTACTTCACTGCATCGGGGGAATGGCCAATGCTCAAGTAAACTGTTGGCCATTGGTTGTTATAGCTGGCTCGTGTCCTGAAGATCATGAAGCTATTGGTGGCTTCCAGGAATGGCCTCAGGTGGATTCTAGTCGCATGTACTGCAAGTATGCAGCCCGGCCGCCCTCCCCCCGTCTGATCCCCCAACACGTGGAGAAAGCTGTGCGACTTGCATTAGCCGGCCGTCCCGGAGTATCATATTTGGACATGCCCGGTACTCTGTTAATGGCAGAAGTGGACGAAGGCAAAGTACCACTAGACTACTACAGCGCAGACACGGTTAAACTGGCTCATCCCGATCCAGCGTTAGTAGATCAAGCGGCAGAATTACTTTCCAAAGCAGAAAGACCCCTGATCATAGTGGGCAAAGGCGCCGCATACGGCAAGGCCGAAGAGGCGATACGAAAACTAGTGGAAAACACAAAATTACCTTTCTTGCCCACACCAATGGGTAAAGGAGTGGTAGCTGACGAATCTGAGTACTGTGTATCAACTGCGCGTACACAAGCTCTACTGAAAGCTGATGTCATACTACTTCTTGGGGCTAGAATGAATTGGATGCTGCACTTTGGACAACCGCCGAGATATGCGCCCGACGTTAAAATTATTCAGGTCGAAATATCTCCTGAAGAATTTCACAACAGCAAGAAATCAGAATTAGCAGTACACTCAGACATTAGACCTTTTACAGAAGCTCTTGTAAAAAGGTTGTCCGAAAGGAAGTTCTCATTGCAACCTCAAAACAACAGTTGGTGGCAGGGACTGAAACAGAAACAAAAAGCAAACACCGAATTTGTAGAGGCTCAAGCAAGCAGCACTGCAGTACCACTGAACTACTACACTGTTTTCAAAACAGTTCAACAAGGCATTCCAAAAGATTCAATCATTGTCAGCGAAGGAGCGAATACCATGGATATTGGCCGAGGTTTATTGCTCAACAATCATCCGAGACACAGGCTAGATGCTGGTACATTTGGCACTATGGGGGTAGGACCTGGCTTCGCTATTGCAGCAGCAATGTGGTGCCGAGACTATGCACCTGGTAAACGTGTCATTTGTGTTGAAGGAGACTCTGCTTTTGGCTTCTCAGGCATGGAAATAGAGACAATGTTCCGGTACAAGTTACCTGTAATTATAATCATAGTAAACAATAATGGAATTTACAATGGGTTTGATAAAGAAGTAATGGCAGATATTCAATCTGGCGGCGATGTTACTCAGTGTACACCACCCACGGCTCTCAGTGGTGAAGTACGATACGAAAAGATGATGGAACTATTCGGCGAGACTGGTCATCTTTGTCGGACAGTCGAGGACATTAAAGAAGCAATTAAAACGGCCACAGCTGTTACTGATAAACCGAGTATCATCAACATCTTGATTGACCCACAGGCTAATAGGAAACCCCAAACGTTCAACTGGCTTACAGAATCCAAACTTTAA

Protein

MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAARPPSPRLIPQHVEKAVRLALAGRPGVSYLDMPGTLLMAEVDEGKVPLDYYSADTVKLAHPDPALVDQAAELLSKAERPLIIVGKGAAYGKAEEAIRKLVENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLKQKQKANTEFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVIIIIVNNNGIYNGFDKEVMADIQSGGDVTQCTPPTALSGEVRYEKMMELFGETGHLCRTVEDIKEAIKTATAVTDKPSIINILIDPQANRKPQTFNWLTESKL

Similarity

Belongs to the TPP enzyme family.

Uniprot

H9JHM0   Q2F5Z5   A0A2W1BJJ2   A0A2A4JNL1   A0A2A4JMR4   A0A212FNE1   + More
A0A194Q0T3   A0A0N0PF82   A0A1B0DFY4   A0A2M4AKI8   W5JMJ4   A0A1Q3FEX5   A0A182YE44   A0A1L8DIW1   A0A182F447   B0X3H9   A0A034VXX4   A0A0K8VJQ2   B0XEM7   A0A182J1B2   A0A182HX25   A0A0Q9WEE0   A0A182H8A9   B4LPP2   W8BQ90   Q16FM3   A0A182NQ01   A0A1L8DIX1   A0A3B0JDI3   A0A1B0C8Q0   A0A182UM71   Q5R276   Q5R297   B4MRW7   B3NK68   Q16UY3   B4H4U9   A0A1I8PT35   B4HQ42   Q7K3B7   B4PAP1   A0A182U2B4   Q28X05   A0A1J1IP78   A0A182R8Z9   A0A0M4ECD2   B3MGS6   A0A1B0CFZ4   A0A1W4VGQ3   A0A182LN42   A0A182QZD9   A0A084WC95   B4JWF9   T1PDL1   A0A1I8N410   Q7QDR1   A0A182W888   A0A1L8EFW2   U5EKE4   A0A0L0CFN2   B4KS24   A0A1L8EHD5   A0A336LEU1   A0A023EUZ6   A0A182M381   A0A2J7Q906   A0A1A9W0X6   A0A1A9VB27   A0A026X0B9   A0A3L8DUG3   A0A158P1B6   A0A1A9ZYI5   A0A067R737   A0A1A9XYA6   A0A182XA82   E0VZ99   A0A195DL26   E2ATX6   A0A1B0G4P0   V5GVD7   E2C220   D6WWN7   A0A1B6DJS5   A0A1B6LZP6   A0A1B6F1Z5   A0A151K0C5   N6U7T1   A0A1B0BUC1   A0A151XGZ4   A0A1Y1KL51   A0A182K8W5   A0A2S2QZ66   A0A182PSC4   A0A0M9A9A6   A0A2S2P9X2   A0A2H8U0N6   A0A0K8TT28   A0A088A1S8   J9K0X7   A0A154P4W9  

Pubmed

19121390    28756777    22118469    26354079    20920257    23761445    + More
25244985    25348373    17994087    26483478    24495485    17510324    15729003    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    15632085    20966253    24438588    25315136    12364791    14747013    17210077    26108605    24945155    24508170    30249741    21347285    24845553    20566863    20798317    18362917    19820115    23537049    28004739    26369729   

EMBL

BABH01012825    BABH01012826    BABH01012827    DQ311277    ABD36222.1    KZ150082    + More
PZC73834.1    NWSH01000967    PCG73366.1    PCG73365.1    AGBW02005912    OWR55255.1    KQ459591    KPI97015.1    LADJ01009455    KPJ20931.1    AJVK01059120    GGFK01007970    MBW41291.1    ADMH02000978    ETN64528.1    GFDL01008947    JAV26098.1    GFDF01007691    JAV06393.1    DS232315    EDS39871.1    GAKP01010791    JAC48161.1    GDHF01013212    JAI39102.1    DS232845    EDS26088.1    APCN01005120    CH940648    KRF79342.1    JXUM01030206    KQ560877    KXJ80509.1    EDW60280.1    GAMC01014856    JAB91699.1    CH478411    EAT33038.1    GFDF01007692    JAV06392.1    OUUW01000001    SPP73300.1    AJWK01001234    AB162351    BAD72915.1    AB162349    CM002911    BAD72897.1    KMY95221.1    CH963850    EDW74856.2    CH954179    EDV55277.1    CH477609    EAT38352.1    CH479210    EDW32785.1    CH480816    EDW48667.1    AE013599    AY058683    AAF57501.1    AAL13912.1    CM000158    EDW91432.1    CM000071    EAL26511.1    CVRI01000057    CRL01968.1    CP012524    ALC41365.1    CH902619    EDV36834.1    AJWK01010573    AXCN02002286    ATLV01022612    KE525334    KFB47839.1    CH916375    EDV98297.1    KA646846    AFP61475.1    AAAB01008849    EAA07115.3    GFDG01001310    JAV17489.1    GANO01001843    JAB58028.1    JRES01000462    KNC31012.1    CH933808    EDW10460.1    GFDG01000657    JAV18142.1    UFQS01003096    UFQT01003096    SSX15181.1    SSX34557.1    GAPW01000781    JAC12817.1    AXCM01003116    AXCM01003117    NEVH01016943    PNF25061.1    KK107046    EZA61740.1    QOIP01000004    RLU23932.1    ADTU01006210    ADTU01006211    ADTU01006212    KK852699    KDR18238.1    DS235851    EEB18705.1    KQ980762    KYN13585.1    GL442747    EFN63107.1    CCAG010021607    GALX01004268    JAB64198.1    GL452067    EFN77971.1    KQ971361    EFA08110.1    GEDC01011393    JAS25905.1    GEBQ01010867    JAT29110.1    GECZ01025463    JAS44306.1    KQ981301    KYN43039.1    APGK01036344    KB740939    ENN77730.1    JXJN01020611    KQ982138    KYQ59674.1    GEZM01083860    JAV60970.1    GGMS01013855    MBY83058.1    KQ435710    KOX79840.1    GGMR01013634    MBY26253.1    GFXV01007934    MBW19739.1    GDAI01000084    JAI17519.1    ABLF02013065    KQ434819    KZC06969.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000092462    + More
UP000000673    UP000076408    UP000069272    UP000002320    UP000075880    UP000075840    UP000008792    UP000069940    UP000249989    UP000008820    UP000075884    UP000268350    UP000092461    UP000075903    UP000007798    UP000008711    UP000008744    UP000095300    UP000001292    UP000000803    UP000002282    UP000075902    UP000001819    UP000183832    UP000075900    UP000092553    UP000007801    UP000192221    UP000075882    UP000075886    UP000030765    UP000001070    UP000095301    UP000007062    UP000075920    UP000037069    UP000009192    UP000075883    UP000235965    UP000091820    UP000078200    UP000053097    UP000279307    UP000005205    UP000092445    UP000027135    UP000092443    UP000076407    UP000009046    UP000078492    UP000000311    UP000092444    UP000008237    UP000007266    UP000078541    UP000019118    UP000092460    UP000075809    UP000075881    UP000075885    UP000053105    UP000005203    UP000007819    UP000076502   

PRIDE

H9JHM0    Q2F5Z5    Q7K3B7   

Pfam

PF02775   TPP_enzyme_C        + More
PF02776   TPP_enzyme_N
PF00205   TPP_enzyme_M

Interpro

IPR029061   THDP-binding        + More
IPR011766   TPP_enzyme-bd_C       
IPR012001   Thiamin_PyroP_enz_TPP-bd_dom       
IPR029035   DHS-like_NAD/FAD-binding_dom       
IPR012000   Thiamin_PyroP_enz_cen_dom       

SUPFAM

SSF52518   SSF52518        + More
SSF52467   SSF52467       

ProteinModelPortal

H9JHM0   Q2F5Z5   A0A2W1BJJ2   A0A2A4JNL1   A0A2A4JMR4   A0A212FNE1   + More
A0A194Q0T3   A0A0N0PF82   A0A1B0DFY4   A0A2M4AKI8   W5JMJ4   A0A1Q3FEX5   A0A182YE44   A0A1L8DIW1   A0A182F447   B0X3H9   A0A034VXX4   A0A0K8VJQ2   B0XEM7   A0A182J1B2   A0A182HX25   A0A0Q9WEE0   A0A182H8A9   B4LPP2   W8BQ90   Q16FM3   A0A182NQ01   A0A1L8DIX1   A0A3B0JDI3   A0A1B0C8Q0   A0A182UM71   Q5R276   Q5R297   B4MRW7   B3NK68   Q16UY3   B4H4U9   A0A1I8PT35   B4HQ42   Q7K3B7   B4PAP1   A0A182U2B4   Q28X05   A0A1J1IP78   A0A182R8Z9   A0A0M4ECD2   B3MGS6   A0A1B0CFZ4   A0A1W4VGQ3   A0A182LN42   A0A182QZD9   A0A084WC95   B4JWF9   T1PDL1   A0A1I8N410   Q7QDR1   A0A182W888   A0A1L8EFW2   U5EKE4   A0A0L0CFN2   B4KS24   A0A1L8EHD5   A0A336LEU1   A0A023EUZ6   A0A182M381   A0A2J7Q906   A0A1A9W0X6   A0A1A9VB27   A0A026X0B9   A0A3L8DUG3   A0A158P1B6   A0A1A9ZYI5   A0A067R737   A0A1A9XYA6   A0A182XA82   E0VZ99   A0A195DL26   E2ATX6   A0A1B0G4P0   V5GVD7   E2C220   D6WWN7   A0A1B6DJS5   A0A1B6LZP6   A0A1B6F1Z5   A0A151K0C5   N6U7T1   A0A1B0BUC1   A0A151XGZ4   A0A1Y1KL51   A0A182K8W5   A0A2S2QZ66   A0A182PSC4   A0A0M9A9A6   A0A2S2P9X2   A0A2H8U0N6   A0A0K8TT28   A0A088A1S8   J9K0X7   A0A154P4W9  

PDB

2Q29     E-value=7.39175e-89,     Score=836

KEGG

692884    K12261 2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-] | (RefSeq) 2-hydroxyphytanoyl-CoA lyase

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0003824   GO:0000287   GO:0030976   GO:0016829   GO:0016021   GO:0001561   GO:0016830   GO:0005777   GO:0008949   GO:0015934   GO:0005576   GO:0016042   GO:0005634   GO:0006334   GO:0003779  

Length:

569

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.71742

Exp number, first 60 AAs:

10.38022

Total prob of N-in:

0.49077

POSSIBLE N-term signal

sequence

outside

1  -  569

 

 

Pi

200.260952

Theta

186.969762

Tajima's D

0.184825

CLR

1.605919

CSRT

0.420628968551572

Interpretation

Uncertain