Gene

KWMTBOMO01277

Pre Gene Modal

BGIBMGA009019

Annotation

PREDICTED:_pickpocket_protein_28-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr3(-):7257867-7268498      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.567

CDS

ATGAAAGTCGGGAATGCCCGAAACACAGCTAAGTCGCTTCTTGTCAACTCGAATGGTACGCGGATGAATGCTTTGGTTCCAGATAGTAGAGAGAACTTCTGTTCTTATGACAGATCCGGAAGCACCGGAAGGATCCCTGACCATGATTTGGAGAAAAGCCGTGAGATAAACGAATACCTGAACTTCAAGGATAAACCTAAGAAATCAAATTTTATCAAAGACTACATCATAGATTACACAGCGAATTCAAATCTGCACGGTCTTAAGTACATCGGTGAAAAGGAACGGACTATAGTTGAGAAAATATTTTGGTTGTTTGCATTCATCTGCTGTTTAGTGATTTGCGCTGGACTAATAGGAAAACTGTGGAATAAATGGAACGTGAATCCCGTCATCGTTAGCTTTGCGGAAAATCCGACACCTGTGTACCAGATACCTTATCCGGCTGTAACACTGTGTTTTGAAACGAAAGCTATGCAAAGGAAATTTAATTTCACAGAATACTATCATCTTTATAACAATACTGAAACGTACTCAAATCTTACGGAACAAGAACGACACCTTTTCGAAGATGTGTCTATGGTTTGCGACGATCACTTAGCACCACGAAAGGGTCGGAAAACTTCGTCTGGATATGAATTGGTCAATCACATAACGGAGATTTCGCCAAATCTCACGGATGTATTCTTAGGTTGCAAATGGAAAGACATAACGAAACCCAACTGCTCCGATTTATTCTCGCCGATAATTACCGAGGAAGGCCTATGTTACACTTTCAATACTCTAGGAAACGATGAACTTTTCCGAACTGAGAATTTGCACAGCGACTATCGATATTTAGAGCACGAAAACCTCGTGGGGTCATGGTCTTTAGATGGCGGCTATGAGCCAAACACCCCCATAGAAACTTACCCGCACCGAGGATCTGGGTACGGAGCAAAATCTGGATTGACGATGTTATTGAAAGCTGCAAATCTTGATCTTGACTACCTTTGTAAAGGTCCCGTCCAAGGATTTAAAATATTGCTGCACAACCCAGCAGAACTGCCAAGAGTATCGCAGCAGTATTTCCGATCTCCATTATCACAAGAAGTTGTGGTAGCTGTGAAACCTAAAATGATGACGACTTCGGAAGGATTACGACCATACGAAGCGAAAAGGCGTCTATGTTATTTCCCGAATGAACGCTATCTCCGCTACTTCAAAGTGTATACACAAGCTAACTGTGAGATGGAATGTTTATCCAACTTCACGTATACGAGATGCGGCTGTGTACATTTCGGGATGCCACATGATTCTAACATGTCCGTGTGCAACGCGGGCAGCATGCCGTGCATAAAACATGCTCAAATGGATCTTGTGACGATAGCGATAGAAACTGGTTTGGACGACTCATTCGATGCTGATGCTCTAGACAACGCAAAGAAGGTGTCCGCAAAATGCGACTGCCTTCCATCCTGCACCTCCATAGAATATGAAGCTGAAACATCCCAGGCGGATTTCGACTGCCTTGCGCTTTTCAGAGCCTTTAGATATAATGTTTCTGAATTTGTAAAAGATGTCAGCTACGCTCGAATTATGATATTCTTTAAAGAAGCACAATTCATAACATCGAGACGATCGGAACTTTACGGTCAAACAGACTTCCTGGCCAACAGCGGAGGTCTGCTGGGTCTGTTCATGGGTTTCTCGTTTTTGAGCCTCATCGAAATAGTATACTTTTTATCCTTAAGAATCATCTGTGTCCTCTTCAAGCGAAAAAACAAAAAACAGATGATGAATTTCCCAAAAGATAATCTCACCAGTCCCGAGTTCTACAAATCATCAAATGAATAA

Protein

MKVGNARNTAKSLLVNSNGTRMNALVPDSRENFCSYDRSGSTGRIPDHDLEKSREINEYLNFKDKPKKSNFIKDYIIDYTANSNLHGLKYIGEKERTIVEKIFWLFAFICCLVICAGLIGKLWNKWNVNPVIVSFAENPTPVYQIPYPAVTLCFETKAMQRKFNFTEYYHLYNNTETYSNLTEQERHLFEDVSMVCDDHLAPRKGRKTSSGYELVNHITEISPNLTDVFLGCKWKDITKPNCSDLFSPIITEEGLCYTFNTLGNDELFRTENLHSDYRYLEHENLVGSWSLDGGYEPNTPIETYPHRGSGYGAKSGLTMLLKAANLDLDYLCKGPVQGFKILLHNPAELPRVSQQYFRSPLSQEVVVAVKPKMMTTSEGLRPYEAKRRLCYFPNERYLRYFKVYTQANCEMECLSNFTYTRCGCVHFGMPHDSNMSVCNAGSMPCIKHAQMDLVTIAIETGLDDSFDADALDNAKKVSAKCDCLPSCTSIEYEAETSQADFDCLALFRAFRYNVSEFVKDVSYARIMIFFKEAQFITSRRSELYGQTDFLANSGGLLGLFMGFSFLSLIEIVYFLSLRIICVLFKRKNKKQMMNFPKDNLTSPEFYKSSNE

Similarity

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Uniprot

H9JHM1   A0A2W1BGB8   A0A194PW83   A0A2H1WS18   A0A212EHF3   D6WXM6   + More
A0A1B0GL64   A0A1W4XR61   U4UGG3   B3M5Z2   A0A0M3QW07   T1H7R9   B4ML83   B4PC79   B4HV75   A0A0J9RQW9   A0A1S4F6X7   Q9VS73   A0A034WQE2   B3NFC4   A0A0L0CPJ6   A0A3B0JWU3   B4LE48   A0A182MYI9   B4J292   A0A182QS19   A0A182THH2   A0A182MLZ3   A0A1I8Q829   A0A182HQ19   A0A182XD77   A0A182UXK6   A0A182W972   Q2M133   Q17DP0   A0A182Y1U0   A0A182K171   A0A1I8M8B2   A0A182KSP4   A0A1W4U6V2   A0A336L784   A0A182J6D0   A0A182R5F2   B4KYR2   A0A084WHX7   A0A182FU38   A0A182PBQ5   W5JNH9   A0A182G5B3   A0A1J1HMY9   B0W821   Q7Q066   A0A1B0GH50   A0A084WHX6   A0A1B0FK79   B0WKI1   A0A0K8SJE9   A0A1S4EX90   A0A0A9XCD9   B4M371   Q17MX3   A0A1A9WD09   A0A182IW77   B0WKI4   B4N9B6   A0A182H7C8   A0A1B0DLX5   A0A1S4G1A5   A0A0Q9WPD7   B4GUR0   A0A0M3QZM1   A0A1S4H812   B5RJJ1   O46342   A0A1W4UQ48   A0A182RAN0   B3P232   A0A1W4V2C9   B4PUF8   B4QVK8   A0A084WGS5   T1GJ31   Q16GX7   A0A182INZ7   B3M0N3   A0A0B4K691   A0A182YLS3   A0A0L0CPB4   A0A1A9X593   A0A182PN37   A0A1B0AK60   A0A182GRH0   A0A182Q221   A0A182MXN7   A0A1A9X8U4   A0A182PN36   A0A1B0AX56   B4GFB0   A0A182WEP1  

Pubmed

19121390    28756777    26354079    22118469    18362917    19820115    + More
23537049    17994087    17550304    22936249    17510324    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25348373    26108605    15632085    25244985    25315136    20966253    24438588    20920257    23761445    26483478    12364791    14747013    17210077    25401762    9600094    9545267    9425162    26109357    26109356   

EMBL

BABH01012830    KZ150082    PZC73838.1    KQ459591    KPI97019.1    ODYU01010562    + More
SOQ55762.1    AGBW02014900    OWR40914.1    KQ971362    EFA08873.2    AJWK01034404    AJWK01034405    KB632186    ERL89696.1    CH902618    EDV40708.1    CP012525    ALC43319.1    ACPB03005214    CH963847    EDW73141.1    CM000159    EDW93764.1    CH480817    EDW50846.1    CM002912    KMY98102.1    AE014296    AAF50555.3    GAKP01001166    JAC57786.1    CH954178    EDV50466.2    JRES01000080    KNC34298.1    OUUW01000002    SPP77191.1    CH940647    EDW69004.1    CH916366    EDV97043.1    AXCN02001041    AXCM01007075    APCN01003288    CH379069    EAL30743.2    CH477292    EAT44535.1    UFQS01001781    UFQT01001781    SSX12335.1    SSX31786.1    AXCP01006762    CH933809    EDW17776.1    ATLV01023896    KE525347    KFB49821.1    ADMH02001044    ETN64334.1    JXUM01043285    KQ561357    KXJ78848.1    CVRI01000004    CRK87601.1    DS231856    EDS38483.1    AAAB01008986    EAA00234.4    AJWK01003969    AJWK01003970    AJWK01003971    AJWK01003972    KFB49820.1    CCAG010004974    DS231972    EDS29857.1    GBRD01012396    JAG53428.1    GBHO01025985    JAG17619.1    CH940651    EDW65246.1    CH477203    EAT48029.1    EDS29860.1    CH964232    EDW80549.1    JXUM01116018    KQ565940    KXJ70514.1    AJVK01016585    AJVK01016586    CH933810    KRF94123.1    CH479191    EDW26343.1    CP012528    ALC49619.1    BT044465    ACH92530.1    AF043264    AE014297    Y16240    AAC38824.1    AAF52108.2    CAA76129.1    CH954181    EDV47805.1    CM000160    EDW95680.2    CM000364    EDX11633.1    ATLV01023713    KE525345    KFB49419.1    CAQQ02088033    CH478228    EAT33496.1    CH902617    EDV44280.2    AFH06228.1    JRES01000091    KNC34208.1    JXUM01082415    KQ563311    KXJ74085.1    AXCN02001053    JXJN01005088    CH479182    EDW34295.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000007266    UP000092461    UP000192223    + More
UP000030742    UP000007801    UP000092553    UP000015103    UP000007798    UP000002282    UP000001292    UP000000803    UP000008711    UP000037069    UP000268350    UP000008792    UP000075884    UP000001070    UP000075886    UP000075902    UP000075883    UP000095300    UP000075840    UP000076407    UP000075903    UP000075920    UP000001819    UP000008820    UP000076408    UP000075881    UP000095301    UP000075882    UP000192221    UP000075880    UP000075900    UP000009192    UP000030765    UP000069272    UP000075885    UP000000673    UP000069940    UP000249989    UP000183832    UP000002320    UP000007062    UP000092444    UP000091820    UP000092462    UP000008744    UP000000304    UP000015102    UP000092445    UP000092443    UP000092460   

PRIDE

H9JHM1    Q9VS73    B5RJJ1    O46342   

Pfam

PF00858   ASC        + More
PF11838   ERAP1_C
PF01433   Peptidase_M1

Interpro

IPR001873   ENaC        + More
IPR020903   ENaC_CS       
IPR042097   Aminopeptidase_N-like_N       
IPR014782   Peptidase_M1_dom       
IPR024571   ERAP1-like_C_dom       
IPR033581   APN2       
IPR001930   Peptidase_M1       
IPR034016   M1_APN-typ       

Gene 3D

2.60.40.1730    

CDD

cd09601  M1_APN_2

ProteinModelPortal

H9JHM1   A0A2W1BGB8   A0A194PW83   A0A2H1WS18   A0A212EHF3   D6WXM6   + More
A0A1B0GL64   A0A1W4XR61   U4UGG3   B3M5Z2   A0A0M3QW07   T1H7R9   B4ML83   B4PC79   B4HV75   A0A0J9RQW9   A0A1S4F6X7   Q9VS73   A0A034WQE2   B3NFC4   A0A0L0CPJ6   A0A3B0JWU3   B4LE48   A0A182MYI9   B4J292   A0A182QS19   A0A182THH2   A0A182MLZ3   A0A1I8Q829   A0A182HQ19   A0A182XD77   A0A182UXK6   A0A182W972   Q2M133   Q17DP0   A0A182Y1U0   A0A182K171   A0A1I8M8B2   A0A182KSP4   A0A1W4U6V2   A0A336L784   A0A182J6D0   A0A182R5F2   B4KYR2   A0A084WHX7   A0A182FU38   A0A182PBQ5   W5JNH9   A0A182G5B3   A0A1J1HMY9   B0W821   Q7Q066   A0A1B0GH50   A0A084WHX6   A0A1B0FK79   B0WKI1   A0A0K8SJE9   A0A1S4EX90   A0A0A9XCD9   B4M371   Q17MX3   A0A1A9WD09   A0A182IW77   B0WKI4   B4N9B6   A0A182H7C8   A0A1B0DLX5   A0A1S4G1A5   A0A0Q9WPD7   B4GUR0   A0A0M3QZM1   A0A1S4H812   B5RJJ1   O46342   A0A1W4UQ48   A0A182RAN0   B3P232   A0A1W4V2C9   B4PUF8   B4QVK8   A0A084WGS5   T1GJ31   Q16GX7   A0A182INZ7   B3M0N3   A0A0B4K691   A0A182YLS3   A0A0L0CPB4   A0A1A9X593   A0A182PN37   A0A1B0AK60   A0A182GRH0   A0A182Q221   A0A182MXN7   A0A1A9X8U4   A0A182PN36   A0A1B0AX56   B4GFB0   A0A182WEP1  

PDB

4NYK     E-value=0.0122527,     Score=93

KEGG

101738057    K03440 acid-sensing ion channel, other | (RefSeq) pickpocket protein 28-like

GO

GO:0016021   GO:0005272   GO:0035179   GO:0050966   GO:0032590   GO:0006814   GO:0008270   GO:0008237   GO:0050975   GO:0030424   GO:0030425   GO:0043025   GO:0016020   GO:0015934   GO:0005576   GO:0016042   GO:0005634   GO:0006334   GO:0003779  

PANTHER

PTHR11690   PTHR11533:SF246  

Length:

611

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

43.65928

Exp number, first 60 AAs:

0

Total prob of N-in:

0.99591

inside

1  -  101

TMhelix

102  -  124

outside

125  -  561

TMhelix

562  -  584

inside

585  -  611

 

 

Pi

221.662168

Theta

199.138322

Tajima's D

-1.948326

CLR

1.200512

CSRT

0.0167991600419979

Interpretation

Uncertain