Gene

KWMTBOMO01249

Pre Gene Modal

BGIBMGA008854

Annotation

protein_kinase?_cGMP-dependent?_type_I_[Bombyx_mori]

Location

Bomo_Chr3(+):6274025-6274920      View in EpiBrowser

Full name

cGMP-dependent protein kinase      

Location in the cell

Nuclear   Reliability : 2.794

CDS

ATGCGCGTGTGCTTCGACAACCTCTGCTTTGGATCGTCACAGCGCGGAGCTGCTGACGATGAGCCGAGAGCCTTAGTGAATACTGGTGGAGGAGCGCTTACCGTGGCGCCCACAGTCAACGGCGAAAGACGCGCGTTAGACGAAACGTATAGAGAGATCGAGTTAAATGGTATAATGGGGACTCCTACAGCTATGAATGCGGAGTCGGAGAATTGCGTTGCCAATGCAACGATGGCGAATGACATGCAGCCCTTAATCGAACGGATCAGGGAGCTTGAGGCGTTGCTTAAGCAACGTGACCAGGAAATGTTGGAACTGCGCTCGCAGCTGGACAAACTGCAGAGCGTGTTCCCGTACCAGCAGTACGCCCGAGGATCGAGAGGTCCCAGAAAGCAGAGAGCTCAGGGTATATCTGCTGAGCCGCAGAACAGCGCATCGCTTCAAGATCTGACTCATCAGACCTTCCCTATTTACGACAAAAGCGAAACGTGA

Protein

MRVCFDNLCFGSSQRGAADDEPRALVNTGGGALTVAPTVNGERRALDETYREIELNGIMGTPTAMNAESENCVANATMANDMQPLIERIRELEALLKQRDQEMLELRSQLDKLQSVFPYQQYARGSRGPRKQRAQGISAEPQNSASLQDLTHQTFPIYDKSET

Catalytic Activity

ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Similarity

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

Uniprot

H9JH57   Q8T9W9   Q8ST45   A0A2H1V3Y1   A0A194QI85   A0A0L7L5C9   + More
A0A194R8R1   A0A2W1BY46   H6QX52   A0A097F6X4   V9P1J7   V9P2R2   A0A212FGP9   A0A097F6V5   Q0Z847   A0A2P8ZNS3   A0A0T6BC73   A0A1W4WP09   A0A2J7QHK3   A0A139WDK8   A0A1B6J3Z5   A0A1B6C835   A7UV95   A0A1B6MLR1   A0A1Y1MUM7   A0A1B6EZI2   A0A1B6HZD3   A0A139WDE4   A0A0V0G4D3   A0A023F5I7   A0A069DW21   U4U603   N6UGS9   Q06BQ9   A0A088AEL8   E0VGP0   A0A146KTS3   A0A0K8TDE6   A0A0H3WKE9   T1SGQ4   V5GSC1   A0A0N0BEY4  

EC Number

2.7.11.12

Pubmed

19121390    14986923    26354079    26227816    28756777    23742168    + More
25274324    22118469    29403074    18362917    19820115    12364791    28004739    25474469    26334808    23537049    18549955    20566863    26823975   

EMBL

BABH01012938    AF465602    AAL76257.1    AF465600    AF465601    AAL76255.1    + More
AAL76256.1    ODYU01000554    SOQ35509.1    KQ458756    KPJ05273.1    JTDY01002826    KOB70647.1    KQ460597    KPJ13889.1    KZ149910    PZC78157.1    FJ606838    ACU09499.1    KM017967    AIT18204.1    KC310498    AGT28258.1    KC310497    AGT28257.1    AGBW02008607    OWR52921.1    KM017966    AIT18203.1    DQ666642    ABG56236.1    PYGN01000008    PSN58154.1    LJIG01002009    KRT84931.1    NEVH01013973    PNF28060.1    KQ971361    KYB25935.1    GECU01013821    JAS93885.1    GEDC01027640    JAS09658.1    AAAB01008984    EDO63371.1    GEBQ01003172    JAT36805.1    GEZM01020117    GEZM01020116    JAV89393.1    GECZ01026303    JAS43466.1    GECU01027669    GECU01005312    JAS80037.1    JAT02395.1    KYB25934.1    GECL01003210    JAP02914.1    GBBI01002289    JAC16423.1    GBGD01000616    JAC88273.1    KB632064    ERL88497.1    APGK01035548    KB740928    ENN77857.1    DQ913742    ABI97017.1    DS235150    EEB12546.1    GDHC01020067    JAP98561.1    GBRD01002228    JAG63593.1    KP662686    AKM12346.1    KC937056    AGT42008.1    GALX01001407    JAB67059.1    KQ435817    KOX72584.1   

Proteomes

UP000005204    UP000053268    UP000037510    UP000053240    UP000007151    UP000245037    + More
UP000192223    UP000235965    UP000007266    UP000007062    UP000030742    UP000019118    UP000005203    UP000009046    UP000053105   

PRIDE

H9JH57    Q8T9W9    Q8ST45   

Pfam

PF16808   PKcGMP_CC        + More
PF00027   cNMP_binding
PF00069   Pkinase
PF05225   HTH_psq

Interpro

IPR031831   PKcGMP_CC        + More
IPR000719   Prot_kinase_dom       
IPR035014   STKc_cGK       
IPR000961   AGC-kinase_C       
IPR018488   cNMP-bd_CS       
IPR000595   cNMP-bd_dom       
IPR002374   cGMP_dep_kinase       
IPR017441   Protein_kinase_ATP_BS       
IPR018490   cNMP-bd-like       
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR014710   RmlC-like_jellyroll       
IPR012198   cAMP_dep_PK_reg_su       
IPR009057   Homeobox-like_sf       
IPR007889   HTH_Psq       

SUPFAM

SSF51206   SSF51206        + More
SSF56112   SSF56112       
SSF46689   SSF46689       

Gene 3D

2.60.120.10    

CDD

cd00038  CAP_ED
cd05572  STKc_cGK

ProteinModelPortal

H9JH57   Q8T9W9   Q8ST45   A0A2H1V3Y1   A0A194QI85   A0A0L7L5C9   + More
A0A194R8R1   A0A2W1BY46   H6QX52   A0A097F6X4   V9P1J7   V9P2R2   A0A212FGP9   A0A097F6V5   Q0Z847   A0A2P8ZNS3   A0A0T6BC73   A0A1W4WP09   A0A2J7QHK3   A0A139WDK8   A0A1B6J3Z5   A0A1B6C835   A7UV95   A0A1B6MLR1   A0A1Y1MUM7   A0A1B6EZI2   A0A1B6HZD3   A0A139WDE4   A0A0V0G4D3   A0A023F5I7   A0A069DW21   U4U603   N6UGS9   Q06BQ9   A0A088AEL8   E0VGP0   A0A146KTS3   A0A0K8TDE6   A0A0H3WKE9   T1SGQ4   V5GSC1   A0A0N0BEY4  

KEGG

692605    K07376 cGMP-dependent protein kinase 1 [EC:2.7.11.12] | (RefSeq) PKG-I, PKG-II; protein kinase, cGMP

GO

GO:0030553   GO:0004692   GO:0005524   GO:0016301   GO:0008603   GO:0005952   GO:0030552   GO:0003677  

Length:

163

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00444

Exp number, first 60 AAs:

0.00444

Total prob of N-in:

0.10481

outside

1  -  163

 

 

Pi

263.781117

Theta

216.734408

Tajima's D

0.564331

CLR

0.031991

CSRT

0.532923353832308

Interpretation

Uncertain