Gene

KWMTBOMO01248

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr3(-):6233187-6237494      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
Probable RNA-directed DNA polymerase from transposon BS      
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.082

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCAGAGTTTCTGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCGTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTAACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTTCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTACATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCGGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATGATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTAATCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACATTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNDPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPINLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   A0A2S2PPK8   A0A023EYS8   X1WNI2   A0A2S2QEE0   A0A224XB44   K7IN67   A0A2J7PU96   A0A023EZE6   A0A224X6Q4   A0A2J7QR37   A0A2J7QY69   A0A2J7R7D0   A0A2J7PBY3   A0A2S2Q383   J9LC21   A0A224XF24   J9M522   X1WZH0   A0A1Y1LKN6   A0A2J7Q6J2   A0A224X6S1   A0A224XI99   A0A2M4BD67   A0A224X6T4   A0A2M4BDV6   A0A2J7PQB5   A0A224X6U5   A0A224XJI0   J9LFC9   A0A2S2N814   A0A2S2NH02   A0A087UGF5   A0A2S2NGV8   A0A0A9YJ00   A0A2J7PDM0   A0A2J7QB68   A0A3N5Z7I3   Q9NBX4   A0A2H8TF37   A0A1Y1KFR3   A0A224X746   A0A2S2PJG2   A0A224XIB0   Q95SX7   A0A0A9YU04   Q07995   A0A224X6W2   A0A2S2N6Q7   A0A0V0G5B6   A0A023F069   A0A2S2R9D4   A0A2J7PVX3   A0A069DX78   A0A069DZL8   A0A2H8TKI9   A0A224X6R6   A0A2A4K918   A0A224X724   A0A023F0I3   X1WIX8   A0A2S2NPG3   A0A087UCW3   A0A142LX26   A0A2S2P698   A0A2M4BD66   J9KSK5   A0A2M4BDA5   A0A2M4BD62   A0A2S2NPJ7   A0A2S2P6S3   A0A142LX49   P21328  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    25401762    30086797    11405632    7753626    12537569    8387152    26334808    25527032    2463954    3040362    1714378   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    GGMR01018716    MBY31335.1    GBBI01004395    JAC14317.1    ABLF02008153    ABLF02008462    ABLF02008464    GGMS01006359    MBY75562.1    GFTR01008262    JAW08164.1    NEVH01021205    PNF19912.1    GBBI01004571    JAC14141.1    GFTR01008279    JAW08147.1    NEVH01011985    PNF31054.1    NEVH01009134    PNF33528.1    NEVH01006736    PNF36716.1    NEVH01027074    PNF13841.1    GGMS01002992    MBY72195.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GFTR01008038    JAW08388.1    ABLF02024246    ABLF02034467    GEZM01053022    JAV74219.1    NEVH01017470    PNF24199.1    GFTR01008271    JAW08155.1    GFTR01008256    JAW08170.1    GGFJ01001858    MBW50999.1    GFTR01008261    JAW08165.1    GGFJ01001857    MBW50998.1    NEVH01022639    PNF18527.1    GFTR01008251    JAW08175.1    GFTR01008257    JAW08169.1    ABLF02023911    GGMR01000676    MBY13295.1    GGMR01003864    MBY16483.1    KK119692    KFM76444.1    GGMR01003407    MBY16026.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01026386    PNF14434.1    NEVH01016302    PNF25823.1    RPOV01000134    RPJ78669.1    AF237761    AAF81411.1    GFXV01000908    MBW12713.1    GEZM01084969    JAV60363.1    GFTR01008151    JAW08275.1    GGMR01016905    MBY29524.1    GFTR01008246    JAW08180.1    AY060438    AAL25477.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    S59870    AAB26437.2    GFTR01008260    JAW08166.1    GGMR01000226    MBY12845.1    GECL01003538    JAP02586.1    GBBI01003810    JAC14902.1    GGMS01017365    MBY86568.1    NEVH01020940    PNF20481.1    GBGD01000389    JAC88500.1    GBGD01000415    JAC88474.1    GFXV01002840    MBW14645.1    GFTR01008269    JAW08157.1    NWSH01000032    PCG80496.1    GFTR01008169    JAW08257.1    GBBI01003747    JAC14965.1    ABLF02017874    ABLF02027031    GGMR01006408    MBY19027.1    KK119261    KFM75202.1    KU543673    AMS38352.1    GGMR01012305    MBY24924.1    GGFJ01001844    MBW50985.1    ABLF02014118    ABLF02014121    ABLF02054790    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGMR01006491    MBY19110.1    GGMR01012443    MBY25062.1    KU543685    AMS38375.1    M22874    M38643   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000054359    + More
UP000218220   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q9NBX4    Q95SX7    P21328    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   A0A2S2PPK8   A0A023EYS8   X1WNI2   A0A2S2QEE0   A0A224XB44   K7IN67   A0A2J7PU96   A0A023EZE6   A0A224X6Q4   A0A2J7QR37   A0A2J7QY69   A0A2J7R7D0   A0A2J7PBY3   A0A2S2Q383   J9LC21   A0A224XF24   J9M522   X1WZH0   A0A1Y1LKN6   A0A2J7Q6J2   A0A224X6S1   A0A224XI99   A0A2M4BD67   A0A224X6T4   A0A2M4BDV6   A0A2J7PQB5   A0A224X6U5   A0A224XJI0   J9LFC9   A0A2S2N814   A0A2S2NH02   A0A087UGF5   A0A2S2NGV8   A0A0A9YJ00   A0A2J7PDM0   A0A2J7QB68   A0A3N5Z7I3   Q9NBX4   A0A2H8TF37   A0A1Y1KFR3   A0A224X746   A0A2S2PJG2   A0A224XIB0   Q95SX7   A0A0A9YU04   Q07995   A0A224X6W2   A0A2S2N6Q7   A0A0V0G5B6   A0A023F069   A0A2S2R9D4   A0A2J7PVX3   A0A069DX78   A0A069DZL8   A0A2H8TKI9   A0A224X6R6   A0A2A4K918   A0A224X724   A0A023F0I3   X1WIX8   A0A2S2NPG3   A0A087UCW3   A0A142LX26   A0A2S2P698   A0A2M4BD66   J9KSK5   A0A2M4BDA5   A0A2M4BD62   A0A2S2NPJ7   A0A2S2P6S3   A0A142LX49   P21328  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1124

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.13423000000001

Exp number, first 60 AAs:

0.00076

Total prob of N-in:

0.00024

outside

1  -  1124

 

 

Pi

10.085753

Theta

19.244314

Tajima's D

0

CLR

396.870614

CSRT

0.376431178441078

Interpretation

Uncertain