Gene

KWMTBOMO01240

Pre Gene Modal

BGIBMGA008850

Annotation

PREDICTED:_dual_3'?5'-cyclic-AMP_and_-GMP_phosphodiesterase_11_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr3(+):6018135-6038550      View in EpiBrowser

Full name

Phosphodiesterase      

Location in the cell

Nuclear   Reliability : 2.158

CDS

ATGGATTATTTGTTGTGCGATTACTGTGGTCTACATTTGCAGAGCATAGAAGAGCCGGTGGGTGGGGCGGGCGGTGGCATGCCCGCGCCCACCTGCTACGACGCGGAGTGTGCCCGCACGGAAGCCTGGCTCGATGAAAACCAGGAGTTCGTGCATGACTACTTCTTGAGGAAAGCGACGCGGCAAGTGGTGGACGCGTGGTTGGTTTCGCACGCGACCCCTCCCAGCGCTGAGCTAGCGTCGCCGTCGAGGGCTGGCTCTGGATCTGGAGCGACAACACCTGTCAGGAAGATCTCGGCGCATGAGTTCGAGCGCGGTGGTCTTTTGAAGCCGCTGGTAACCACCGTGGATGGCACGCCAACTTTCCTCGGAGACCAGCCGCCGCATGCCACTCCGACACGACCGCAGCGTCGCTCCAGGCATGAGCTGAGGCAGCTAGATGAGAAGGAGCTTATATTTGAGCTACGGTGA

Protein

MDYLLCDYCGLHLQSIEEPVGGAGGGMPAPTCYDAECARTEAWLDENQEFVHDYFLRKATRQVVDAWLVSHATPPSAELASPSRAGSGSGATTPVRKISAHEFERGGLLKPLVTTVDGTPTFLGDQPPHATPTRPQRRSRHELRQLDEKELIFELR

Cofactor

a divalent metal cation

Similarity

Belongs to the cyclic nucleotide phosphodiesterase family.

Uniprot

A0A212F5Z9   A0A2A4JRT0   A0A2W1BX00   A0A194R7T1   A0A0T6B596   D6WXS4   + More
V5GVX2   N6U5Q9   U4U9I9   A0A067R4U9   A0A0J7NDR4   A0A026W6P7   A0A182G307   A0A336LU68   A0A195CCX4   A0A1B6EU68   A0A336LQJ2   A0A182X5V4   A0A336LTF2   A0A158NNF5   A0A1L8DLW0   A0A1B6KQ32   A0A1B6FST7   A0A182P1L5   A0A1B6MJU5   A0A182QHF9   A0A1B6IEG8   A0A151WUW1   A0A088AHD5   A0A2P8Z073   A0A2J7QW65   A0A0C9RZC1   A0A182MGZ5   A0A0L7RKM4   Q17CK8   E0VX88   E9IP50   A0A1S4F7V7   A0A1Y9IUW3   A0A182YN76   Q7Q8G2   A0A1I8JU78   E1ZV78   A0A0C9RZA0   A0A0C9QUJ7   A0A2C9GQ76   A0A2C9GQ13   A0A1B0DLY5   A0A154PAQ7   A0A2A3E526   A0A1Q3EX09   A0A2M4A1J8   A0A1Q3EW90   A0A182NGQ5   A0A3Q0IYF6   A0A2M4A2J7   A0A2M4A237   A0A2M4CII7   B0X978   A0A2M4A1Y8   A0A182F366   A0A2M4CSJ0   A0A2M3YZ59   A0A2M3YYZ9   A0A2M3Z0K9   A0A2M4BBA8   A0A2M4BBX5   A0A182J222   A0A1B0FN80   A0A1A9W0L3   A0A084W7Q4   E2BX21   A0A182V3S2   A0A1J1IHZ2   A0A2J7QW72   A0A2S2NQX7   T1JEP4  

EC Number

3.1.4.-

Pubmed

22118469    28756777    26354079    18362917    19820115    23537049    + More
24845553    24508170    30249741    26483478    21347285    29403074    17510324    20566863    21282665    25244985    12364791    20798317    24438588   

EMBL

AGBW02010099    OWR49165.1    NWSH01000794    PCG74173.1    KZ149910    PZC78154.1    + More
KQ460597    KPJ13893.1    LJIG01009690    KRT82576.1    KQ971362    EFA07940.2    GALX01004073    JAB64393.1    APGK01039019    APGK01039020    APGK01039021    APGK01039022    APGK01039023    KB740966    ENN76950.1    KB632186    ERL89722.1    KK852699    KDR18162.1    LBMM01006380    KMQ90655.1    KK107373    QOIP01000004    EZA51643.1    RLU23841.1    JXUM01006749    JXUM01006750    JXUM01006751    JXUM01006752    JXUM01006753    KQ560221    KXJ83751.1    UFQT01000114    SSX20233.1    KQ977935    KYM98570.1    GECZ01028280    JAS41489.1    SSX20230.1    SSX20231.1    ADTU01021376    ADTU01021377    ADTU01021378    ADTU01021379    ADTU01021380    ADTU01021381    ADTU01021382    ADTU01021383    ADTU01021384    ADTU01021385    GFDF01006727    JAV07357.1    GEBQ01026653    JAT13324.1    GECZ01016473    JAS53296.1    GEBQ01003804    JAT36173.1    AXCN02002079    GECU01022414    JAS85292.1    KQ982730    KYQ51491.1    PYGN01000258    PSN49905.1    NEVH01009767    PNF32827.1    GBYB01013471    JAG83238.1    AXCM01001804    KQ414568    KOC71369.1    CH477307    EAT44089.1    DS235829    EEB17994.1    GL764457    EFZ17651.1    AAAB01008944    EAA10146.3    GL434441    EFN74937.1    GBYB01013436    JAG83203.1    GBYB01004307    JAG74074.1    APCN01000703    APCN01000704    AJVK01016602    AJVK01016603    KQ434860    KZC08932.1    KZ288365    PBC26837.1    GFDL01015196    JAV19849.1    GGFK01001365    MBW34686.1    GFDL01015471    JAV19574.1    GGFK01001733    MBW35054.1    GGFK01001490    MBW34811.1    GGFL01000978    MBW65156.1    DS232522    EDS43010.1    GGFK01001482    MBW34803.1    GGFL01003963    MBW68141.1    GGFM01000796    MBW21547.1    GGFM01000734    MBW21485.1    GGFM01001316    MBW22067.1    GGFJ01001169    MBW50310.1    GGFJ01001405    MBW50546.1    CCAG010022043    ATLV01021272    KE525315    KFB46248.1    GL451202    EFN79740.1    CVRI01000054    CRK99879.1    PNF32826.1    GGMR01006966    MBY19585.1    JH432127   

Proteomes

UP000007151    UP000218220    UP000053240    UP000007266    UP000019118    UP000030742    + More
UP000027135    UP000036403    UP000053097    UP000279307    UP000069940    UP000249989    UP000078542    UP000076407    UP000005205    UP000075885    UP000075886    UP000075809    UP000005203    UP000245037    UP000235965    UP000075883    UP000053825    UP000008820    UP000009046    UP000075920    UP000076408    UP000007062    UP000075900    UP000000311    UP000075840    UP000092462    UP000076502    UP000242457    UP000075884    UP000079169    UP000002320    UP000069272    UP000075880    UP000092444    UP000091820    UP000030765    UP000008237    UP000075903    UP000183832   

Pfam

PF01590   GAF        + More
PF00233   PDEase_I
PF00003   7tm_3

Interpro

IPR029016   GAF-like_dom_sf        + More
IPR003018   GAF       
IPR023174   PDEase_CS       
IPR023088   PDEase       
IPR002073   PDEase_catalytic_dom       
IPR003607   HD/PDEase_dom       
IPR036971   PDEase_catalytic_dom_sf       
IPR017978   GPCR_3_C       
IPR009057   Homeobox-like_sf       

SUPFAM

SSF46689   SSF46689       

Gene 3D

3.30.450.40     1.10.1300.10    

CDD

cd00077  HDc

ProteinModelPortal

A0A212F5Z9   A0A2A4JRT0   A0A2W1BX00   A0A194R7T1   A0A0T6B596   D6WXS4   + More
V5GVX2   N6U5Q9   U4U9I9   A0A067R4U9   A0A0J7NDR4   A0A026W6P7   A0A182G307   A0A336LU68   A0A195CCX4   A0A1B6EU68   A0A336LQJ2   A0A182X5V4   A0A336LTF2   A0A158NNF5   A0A1L8DLW0   A0A1B6KQ32   A0A1B6FST7   A0A182P1L5   A0A1B6MJU5   A0A182QHF9   A0A1B6IEG8   A0A151WUW1   A0A088AHD5   A0A2P8Z073   A0A2J7QW65   A0A0C9RZC1   A0A182MGZ5   A0A0L7RKM4   Q17CK8   E0VX88   E9IP50   A0A1S4F7V7   A0A1Y9IUW3   A0A182YN76   Q7Q8G2   A0A1I8JU78   E1ZV78   A0A0C9RZA0   A0A0C9QUJ7   A0A2C9GQ76   A0A2C9GQ13   A0A1B0DLY5   A0A154PAQ7   A0A2A3E526   A0A1Q3EX09   A0A2M4A1J8   A0A1Q3EW90   A0A182NGQ5   A0A3Q0IYF6   A0A2M4A2J7   A0A2M4A237   A0A2M4CII7   B0X978   A0A2M4A1Y8   A0A182F366   A0A2M4CSJ0   A0A2M3YZ59   A0A2M3YYZ9   A0A2M3Z0K9   A0A2M4BBA8   A0A2M4BBX5   A0A182J222   A0A1B0FN80   A0A1A9W0L3   A0A084W7Q4   E2BX21   A0A182V3S2   A0A1J1IHZ2   A0A2J7QW72   A0A2S2NQX7   T1JEP4  

PDB

3BJC     E-value=3.58441e-09,     Score=141

KEGG

101738997    K13298 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35] | (RefSeq) dual 3'

GO

GO:0007165   GO:0004114   GO:0046872   GO:0004115   GO:0047555   GO:0004930   GO:0016021   GO:0003677  

Length:

156

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00059

Exp number, first 60 AAs:

0.00022

Total prob of N-in:

0.11048

outside

1  -  156

 

 

Pi

247.862785

Theta

195.368141

Tajima's D

0.714135

CLR

0.535121

CSRT

0.575471226438678

Interpretation

Uncertain