SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01233
Pre Gene Modal
BGIBMGA009034
Annotation
PREDICTED:_uncharacterized_protein_LOC105381223_[Plutella_xylostella]
Full name
Protein quiver      
Alternative Name
Protein sleepless
Location in the cell
PlasmaMembrane   Reliability : 2.897
 

Sequence

CDS
ATGGAAATTAACAAACTTAGTAATTTTGTTGGTTTTTTTATTATTTTTAGCTTAATGCCTCTCGCTCTAAGTATAAAATGTTGGAACTGCAGATCCAGCACCGATCCCAAATGCGCAGATCCTTTCGATAATAGTACAGTACCGATAACTGATTGCAATCAAGAAAAGGGACTTTCGCATTTGCCGGGAATGAAACCAAGCATGTGCCGCAAAATAAGACAAAAAGTTAATGGTGAATGGAGGTACTTCCGTGACTGTGCTTATTTGGGTGAAGTTGGCATTCAAGGAGATGAAAGGTTTTGTCTCATGAGGACTGGTACATACAATATATTTGTAGAATACTGTACTTGTAACAGTAAAGATGGTTGTAATTCTTCTTCAGTCATCAGTCCTTTACCTATATTCTTAGTTGTATTAGTTGCGTTAAGCTCTTTTAAGATAGGGCTCTAA
Protein
MEINKLSNFVGFFIIFSLMPLALSIKCWNCRSSTDPKCADPFDNSTVPITDCNQEKGLSHLPGMKPSMCRKIRQKVNGEWRYFRDCAYLGEVGIQGDERFCLMRTGTYNIFVEYCTCNSKDGCNSSSVISPLPIFLVVLVALSSFKIGL

Summary

Description
Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability.
Similarity
Belongs to the quiver family.
Feature
chain  Protein quiver
EMBL
BABH01012984    ODYU01010604    SOQ55824.1    GDQN01007603    JAT83451.1    KZ149910    + More
PZC78148.1    KQ460317    KPJ16012.1    KQ458756    KPJ05282.1    GAIX01004140    JAA88420.1    GFTR01002456    JAW13970.1    GDKW01004099    JAI52496.1    ACPB03014814    KK107153    QOIP01000012    EZA56953.1    RLU15790.1    NNAY01000427    OXU28481.1    KQ977642    KYN01000.1    KQ435727    KOX78005.1    KQ434870    KZC09603.1    KK854233    PTY13488.1    GL448770    EFN83877.1    GL887491    EGI71014.1    KX950845    ARU12055.1    KQ982585    KYQ54249.1    KQ976625    KYM78968.1    ADTU01018617    KY031019    ATU82770.1    KQ414755    KOC61805.1    KQ980295    KYN16872.1    KZ288263    PBC30340.1    GDHC01005853    JAQ12776.1    KQ981979    KYN31529.1    ADMH02001597    ETN61914.1    JXUM01042353    KQ561321    KXJ78986.1    GECZ01025600    GECZ01016709    JAS44169.1    JAS53060.1    GAPW01005499    JAC08099.1    CH963857    EDW76497.1    GGFJ01010305    MBW59446.1    GECU01004193    JAT03514.1    GGFK01012752    MBW46073.1    DS232456    EDS42043.1    GGFK01012709    MBW46030.1    GGFK01012710    MBW46031.1    NEVH01009767    PNF32830.1    GEBQ01016628    JAT23349.1    ATLV01021269    KE525315    KFB46237.1    GAKP01003370    JAC55582.1    GDHF01028364    JAI23950.1    AE014134    BT044115    KX531517    AAF53178.1    ACH92180.1    ANY27327.1    GGFM01005209    MBW25960.1    PYGN01000077    PSN55054.1    GANO01003458    JAB56413.1    OUUW01000004    SPP79217.1    GBXI01004406    JAD09886.1    GFDL01014113    JAV20932.1    GFDL01014170    JAV20875.1    CH954177    EDV58811.1    JXJN01007544    CH933807    EDW12935.1    CM000361    CM002910    EDX04792.1    KMY89895.1    CM000157    EDW88171.1    AXCN02002080    CH379060    EAL33822.1    CH479180    EDW29060.1    CCAG010008329    CH477307    EAT44085.1    AXCM01014743    CH902620    EDV32140.1    AJWK01001280    GAMC01008761    JAB97794.1    GFDF01005941    JAV08143.1    CH940649    EDW64882.1    CP012523    ALC39388.1    JRES01001399    KNC23181.1    GFDF01002781    JAV11303.1    APCN01000707    AAAB01008944    EAA10235.3    CH916368    EDW04150.1    UFQS01000114    UFQT01000114    SSW99848.1    SSX20228.1    KQ971362    EFA08898.1   
Pfam
PF17064   QVR
Interpro
IPR031424   QVR       

Ontologies

Topology

Subcellular location
Cell membrane  
SignalP
Position:   1 - 24,         Likelihood:  0.977823
 
 
Length:
149
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
37.03738
Exp number, first 60 AAs:
19.15827
Total prob of N-in:
0.25984
POSSIBLE N-term signal
sequence
inside
1  -  6
TMhelix
7  -  25
outside
26  -  127
TMhelix
128  -  145
inside
146  -  149
 
 

Population Genetic Test Statistics

Pi
208.355379
Theta
183.515225
Tajima's D
0.495307
CLR
0.396024
CSRT
0.518174091295435
Interpretation
Uncertain
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