Gene

KWMTBOMO01227

Pre Gene Modal

BGIBMGA009036

Annotation

Spatzle_3_[Operophtera_brumata]

Location

Bomo_Chr3(-):5547659-5562807      View in EpiBrowser

Full name

Protein spaetzle 3      

Alternative Name

Protein spatzle 3

Location in the cell

Extracellular   Reliability : 2.219 Nuclear   Reliability : 1.606

CDS

ATGTACGGTTCGTTTTCGACGCCGCCCGGCAGCCGAGTGAAGAGAGCACCCGGAGTTCCGGATATGCATGACGCATCTGGGGATTCGTACTTCCGTCACGCCAGACAGGCCTCGAACACACAATTGCCTGACGCGCAGGCCGTCAACAGTACCGGAAGGGTGGATGCGTGCGAAAGCAAAACGGAAATCATGACACCATACTGGGCCCTCAACTCGGCAAGGAAACTCCGAGCTATTGTGAACACTATGCACTTTGAACAGGCCATACATCAGGAAACTTGCAGCAAAACCACGACCGGCCGTTGCAACAGAGACTGCGGTTGCGAGCAAAAATACAAATGGCACCGGCTGCTCGCCTACGATCCGTCAGACGACTGCGCCGGTATCTTCATGGACTGGTTCCTATTTCCGTCCTGCTGCGTTTGCAGGTGTAAGCCTTGA

Protein

MYGSFSTPPGSRVKRAPGVPDMHDASGDSYFRHARQASNTQLPDAQAVNSTGRVDACESKTEIMTPYWALNSARKLRAIVNTMHFEQAIHQETCSKTTTGRCNRDCGCEQKYKWHRLLAYDPSDDCAGIFMDWFLFPSCCVCRCKP

Description

Neurotrophin which may function as a ligand to the Toll-related receptor Tollo. Involved in a Tollo and JNK signaling pathway that positively regulates neuromuscular junction (NMJ) growth in presynaptic motorneurons. May function by activating Tollo to promote the phosphorylation of JNK.

Subunit

Homodimer; disulfide-linked.

Miscellaneous

'Spaetzle' means 'noodles' in German.

Keywords

Complete proteome   Disulfide bond   Glycoprotein   Reference proteome   Signal  

Feature

chain  Protein spaetzle 3

Uniprot

A0A2H1W8I0   A0A2W1BII7   A0A0L7LP48   I4DIX1   A0A194QP78   A0A0N0PD68   + More
A0A212FEZ6   A0A154PAP8   A0A0L7R404   N6TJ87   W8BP69   A0A1Y1L4S5   A0A2P8Z087   W8BUS4   A0A088AI16   A0A2A3E6P7   A0A034W838   A0A139WDY4   U4USA6   A0A0A1XK91   A0A195CCN7   A0A0P4VNS9   D6WVG0   T1HBE1   A0A2J7QW82   A0A1B6I005   A0A067RDS5   A0A1B6MPA9   A0A034W9M0   A0A0K8U1K5   A0A0K8UGV4   A0A1B6KRL8   A0A151WV09   Q16F03   A0A1B6GQK7   A0A0L0CFR6   A0A026W7P8   A0A146MA90   Q16YC5   A0A0K8SCA5   A0A182GJZ4   E2B3V4   A0A1B6FJH4   A0A1B6CFB1   A0A0M4ERG5   A0A158NNE9   A0A023EQD2   A0A1B0GKC8   A0A1A9VZP2   A0A1L8E2W5   J9M984   A0A2S2NYA9   A0A1I8M8Y1   E9G890   A0A1I8PC19   A0A1A9V1V7   B4HYB8   A0A0M4E7Y8   B4Q5V0   Q9VLV7   B4LTX0   A0A1I8M8Y4   B3MV06   A0A1A9Z9B9   A0A2S2Q4H9   B4NZ38   B4KHI2   A0A1J1I4D9   A0A1D2MRQ0   B3N6Q4   A0A1B0AWW0   A0A0P5DZP7   A0A224XH44  

Pubmed

28756777    26227816    22651552    26354079    22118469    23537049    + More
24495485    28004739    29403074    25348373    18362917    19820115    25830018    27129103    24845553    17510324    26108605    24508170    30249741    26823975    26483478    20798317    21347285    24945155    25315136    21292972    17994087    22936249    11536362    10731132    12537572    24662564    17550304    27289101   

EMBL

ODYU01006706    SOQ48794.1    KZ150022    PZC74872.1    JTDY01000411    KOB77313.1    + More
AK401239    BAM17861.1    KQ458756    KPJ05286.1    KQ460317    KPJ16014.1    AGBW02008884    OWR52304.1    KQ434860    KZC08923.1    KQ414659    KOC65620.1    APGK01035728    KB740928    ENN77933.1    GAMC01005848    JAC00708.1    GEZM01068363    JAV66965.1    PYGN01000258    PSN49898.1    GAMC01005849    GAMC01005847    JAC00709.1    KZ288365    PBC26839.1    GAKP01008470    JAC50482.1    KQ971357    KYB26146.1    KB632428    ERL95398.1    GBXI01002866    JAD11426.1    KQ977935    KYM98567.1    GDKW01003826    JAI52769.1    EFA09303.2    ACPB03014818    NEVH01009767    PNF32836.1    GECU01027472    JAS80234.1    KK852699    KDR18165.1    GEBQ01002256    JAT37721.1    GAKP01008471    GAKP01008469    JAC50483.1    GDHF01031928    JAI20386.1    GDHF01026744    GDHF01023215    GDHF01018758    JAI25570.1    JAI29099.1    JAI33556.1    GEBQ01025912    JAT14065.1    KQ982730    KYQ51485.1    CH478538    EAT32814.2    GECZ01005037    JAS64732.1    JRES01000438    KNC31253.1    KK107373    QOIP01000004    EZA51646.1    RLU23289.1    GDHC01002454    JAQ16175.1    CH477519    EAT39601.1    GBRD01014895    JAG50931.1    JXUM01069026    JXUM01069027    JXUM01069028    JXUM01069029    KQ562531    KXJ75686.1    GL445407    EFN89623.1    GECZ01019421    GECZ01012448    JAS50348.1    JAS57321.1    GEDC01025215    JAS12083.1    CP012523    ALC39470.1    ADTU01021451    ADTU01021452    ADTU01021453    ADTU01021454    ADTU01021455    ADTU01021456    GAPW01002824    JAC10774.1    AJWK01028669    AJWK01028670    AJWK01028671    AJWK01028672    GFDF01001001    JAV13083.1    ABLF02021002    ABLF02021003    GGMR01009067    MBY21686.1    GL732535    EFX84314.1    CH480818    EDW52048.1    ALC38965.1    CM000361    CM002910    EDX04146.1    KMY88875.1    AF296285    AE014134    AY121674    AAL33883.1    AAM52001.1    CH940649    EDW64021.1    CH902624    EDV33071.2    GGMS01003435    MBY72638.1    CM000157    EDW87702.1    CH933807    EDW11246.1    CVRI01000037    CRK93249.1    LJIJ01000664    ODM95494.1    CH954177    EDV59270.1    JXJN01004955    GDIP01154752    JAJ68650.1    GFTR01004610    JAW11816.1   

Proteomes

UP000037510    UP000053268    UP000053240    UP000007151    UP000076502    UP000053825    + More
UP000019118    UP000245037    UP000005203    UP000242457    UP000007266    UP000030742    UP000078542    UP000015103    UP000235965    UP000027135    UP000075809    UP000008820    UP000037069    UP000053097    UP000279307    UP000069940    UP000249989    UP000008237    UP000092553    UP000005205    UP000092461    UP000091820    UP000007819    UP000095301    UP000000305    UP000095300    UP000078200    UP000001292    UP000000304    UP000000803    UP000008792    UP000007801    UP000092445    UP000002282    UP000009192    UP000183832    UP000094527    UP000008711    UP000092460   

PRIDE

Q9VLV7   

Pfam

PF16077   Spaetzle

Interpro

IPR032104   Spaetzle        + More
IPR029034   Cystine-knot_cytokine       

SUPFAM

SSF57501   SSF57501       

Gene 3D

2.10.90.10    

ProteinModelPortal

A0A2H1W8I0   A0A2W1BII7   A0A0L7LP48   I4DIX1   A0A194QP78   A0A0N0PD68   + More
A0A212FEZ6   A0A154PAP8   A0A0L7R404   N6TJ87   W8BP69   A0A1Y1L4S5   A0A2P8Z087   W8BUS4   A0A088AI16   A0A2A3E6P7   A0A034W838   A0A139WDY4   U4USA6   A0A0A1XK91   A0A195CCN7   A0A0P4VNS9   D6WVG0   T1HBE1   A0A2J7QW82   A0A1B6I005   A0A067RDS5   A0A1B6MPA9   A0A034W9M0   A0A0K8U1K5   A0A0K8UGV4   A0A1B6KRL8   A0A151WV09   Q16F03   A0A1B6GQK7   A0A0L0CFR6   A0A026W7P8   A0A146MA90   Q16YC5   A0A0K8SCA5   A0A182GJZ4   E2B3V4   A0A1B6FJH4   A0A1B6CFB1   A0A0M4ERG5   A0A158NNE9   A0A023EQD2   A0A1B0GKC8   A0A1A9VZP2   A0A1L8E2W5   J9M984   A0A2S2NYA9   A0A1I8M8Y1   E9G890   A0A1I8PC19   A0A1A9V1V7   B4HYB8   A0A0M4E7Y8   B4Q5V0   Q9VLV7   B4LTX0   A0A1I8M8Y4   B3MV06   A0A1A9Z9B9   A0A2S2Q4H9   B4NZ38   B4KHI2   A0A1J1I4D9   A0A1D2MRQ0   B3N6Q4   A0A1B0AWW0   A0A0P5DZP7   A0A224XH44  

KEGG

101743559    no KO assigned | (RefSeq) uncharacterized LOC101743559

GO

GO:0016021   GO:0005121   GO:0008592   GO:0008083   GO:0005576   GO:0021556   GO:0045087   GO:0007399  

Length:

146

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00529

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03237

outside

1  -  146

 

 

Pi

194.6169

Theta

163.766694

Tajima's D

0.255462

CLR

1.307502

CSRT

0.440977951102445

Interpretation

Uncertain