Gene

KWMTBOMO01215

Annotation

PREDICTED:_RNA-directed_DNA_polymerase_from_mobile_element_jockey-like_[Plutella_xylostella]

Location

Bomo_Chr3(+):4779955-4784840      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.798 Nuclear   Reliability : 2.185

CDS

ATGGTGGAGGCCCTTTCTAATTGGCCCCGCCACATGGCTGCCATTAGGGAGCGCCTAGGCCGCGCCCCCTCGGCGCGACCCTTCGGCACTGGTTTTAGGTTCCTGCCGTCGTCGGCTGAGGAATACAGGGCGGTCCAGGCCTACCTGTCGGAGGCCTCTGCCAGGGATAGTACCATTAAATGGTACTGCTATGCCCTGGCGGAGGAGATGCCCTCTAAGGTAGCTGTCCGGGGCCTCCCTGCCGACACCGACACGGCAGACGTTACCAACGCGTTGAAGGAGCTGGGGTTCCCGGCTCGATACGCTAGGTGCATTCGGTCCAAGAGAGGGCGACCGGGCAACGTGTTCCACGTTGCCCTGGATCACCTCTCAAAGGATGAACTCGCCCGCTTGTACTCAGTCAACGAACTGATGTACTTGCCGGGGGTGACGGTTGAGGGATGGCGACCAACCCGAGGGCCTGCGCAGTGTCACCGCTGCCAGGCCTACGGGCACGCCTCCCACAATTGTCACCGTGCGGTCCGCTGCGTGAGATGTGCTGCGGAGCACACTGTAGCGGACTGCCCGAGGCCGAGGGACGGCCCATTCTCCTGCGCCAATTGCGGGAAGGACCACGCCGCCGTTGATAGGCGGTGCCCGGTCTACCGCAAGAAGGCCAGGATGATGGGAGTAACCGTCCCTCCTCCGGTACCACCGGTGCCACCGAGCAAAAGGAAATTGATGAAGAAAGCGCGAAGGGAGGCCTTAGAGAACGCTGCTCCCTCATCGGTTCCCGCAATACCTGCCATAGACATGGAGGTTGACATCAACCCCACTACCGACCACATAATCGATGATCAACAACCTGGAACATCTTCATTGCCCCAGGCACAACCGGCCACTTCAGGCATACAGCCCCCATTACCACCCCGCCCGCAGAGAGAGCGGCGCAGCGGCCGACAGGACACGCAGCCTGCCGGCTTCGCTGCCTGGCTCCTCTCCCTGTGGGAGAAACTGTCCGAGGAGCTGCGCATCATCTACTGGAACCCCGACGGGATAGGGTCCCGGAGGTCGGAGCTCATCCGACTCGCCCAGGAGTATGACCCGCAGGTTATCCTCCTGGGCGAGACCAAGCTCAAACCTCGACAAGATTTTAGGATGCCCAACTACTTCGTGTACCGACGGGACGAACTGACCTCCAACGGGCACCCGTTCAGGGGCACTGCGGCGCTCGTCAGGAGGGACGTGGTGCACGAGGAGCTTGAGCTACTGACCTTCGCCTCTACCAGAACGGTCGGGGTGAGGGTCCACGTACCGGGGGCCGAATTGCGGATTTATGCCGCGTATCGACCCCCGGGTCCTGATTTTGTCGAGGACGATATTAGACGGGCCTTGAACCATGATCGCCATCCGGCCTTGGTGGTCGGGGACCTCAATGCGAAACATGTCGCTTGGGGCTCCCGAATCATCACGCCGCCCGGAAGGCGATTGTACGAGGATGCCGAAAGGGGGGACTACTGCGTGGTCGGCCCCAACGAACCCACACACGTTCCAACGTTGGCCCGGTACCAACCGGACGTATTGGACGTGTGTGTTCACAAGGGGCTACAGTGCCCTCTAGCGATAGAGGCACTGTACGACCTGAGTACCCCTCACCTACCGATCTTGGTCACGGTGGGTTTGGGGCTCACTCGGGTCGCGACATCCCCTCTCAGGCCTAGGGTCGACTGGCAGTCCTTTACGGGACTGCTGGCCGACCAATCCTTGTTTCAAGACCCGTCTACCCCTGATGAGGTCGACACGGCGGCTTCCCGTCTCGTCGACACCATCAGGGGAGCCCTGGACCAAGTGACGACTCTGGTACCCAGCGGGGGGCCCAGAGCGGAACTCCCGGTGCACCTCAAGACGTTAATTCGTCGGAAGAGGGCACTGAGGAGGCTCTGGGCGACATCTAGGTGTCCCAGGATTAAGCGCGAGCTCAACCGACTTGAGGGGGAGCTGGCGACTAGGATGCGGACTTACCGGGGACGAGGGGGAAGACGGTGTTTTACACCGTTGGCTCGTGCCGAAGTCCTGGCCAACTCGCTGGAGCGGCAGTTCACTCCGAATGTCTCTGCACCCTCGATGGCTGCATTCCATCGCGAGGTGTCAGAGGGTGTAATCCAATTCCTCAAACCGGAATCGCCGGGAGTCGAGCTGGGAGATGACGACTTAGTCACTCCCAGCGAGGTGCGCCTCCTCATCAAGTTGATGAAGAGGCGCAAAGCCCCCGGCGAGGACGGTATTCCTCCCCTCGCCCTGCAAAACCTCCCTCCCTCAATCGTGTCAGCAATGACACGATTGTTTAATTCCATTCTCCGGGTAGGACACTTCCCTGGAACTTGGAAACTGGGCAAGATCATCGTCTTGCCCAAACCCGGCAAGGACAGGAGAAAGCCCTCCAGTTACCGACCGATTACCTTGCTCTCGCACGTGGGCAAGTTGTTCGAGCGGCTGCTCCTGAGGAGAATATCGCCGTATATTCTCCTCAGGCCGGAGCAATTCGGCTTTAGAAGCGGCCACTCGACGACTCTGCAACTGACCCGTGTCCTGCATCACTTGGCGGACCGGCGAAACTCGGGCCAATACACGGTCGCGGTCCTCCTCGATATCGAGAAGGCCTTCGACCGTGTGTGGCACGAGGGGCTGGTCCACAAGCTGCGGGACGCGGGCCTACCGCACGCTCACGTGCGACTGCTCGGGTCGTATCTGGAGGGCAGAACCTTCTTTGTCGCGGTCGAGGGCGCACGGTCTTCCGTGCGTCCCATTACGGCCGGGGTTCCCCAGGGTAGTGTCCTATCACCTATCCTATACGCCCTCTACACTAATGACATTCCCACCCTGGAGGGTCACCTTCGGGCGTGGGAGGAGGACGTGAAGTTGGCCTTGTTCGCTGACGACTCGGCCTACTTCTCGTCCTCCCCGTTCCCCTCTGCAGCCATCATGAGGATGCAGAGGCTTTTGGACATACTGCCCCAGTGGCTGGACCGTTGGAGAGTCGCGGTCAATGTGGGAAAGACCGCGGCCTTACTCTACGGTCCGGTCCGTATCAGAGTCGTCCCAAAGAAACTCAGCCTCCGAGGTGTGAATGTCGAGTTCAGGACCACGGTCCGGTATCTCGGATGCGACATCGACCGCTCTTTGAGCATGGTCGCGCACGTCAACCGAGTCATCGGTCAGGCTCGCGCGGCCATGTTCTTGTTGCGGCCGGTGTTTGCGTCCGGGCTTCCGACCAGGACCAAACTCGCCATTTACAAGACATACGTCCGTTCCCGCCTCACATACGCTGCTGTGGCCTGGTATCACCTGTTGTCGCCGTCCCAGCGATCTAGGTTGCAGGCCCAGCAGAGTCTTTCCCTCCGCATTATCGTCGGGGCCGGGCAGTACGTCAGAAATGACGTTATTGCCCGGGACCTAGGGGTGGAGTCGCTCGTGGAGTTTGTGACTAGGCTCGCCCGTAATATGTACGAGCGAGCCGAAAACGGGCCCCATGAGCATCTCCACAACATAGCCCCGCTGCACGCCAGACCACCGGATGGAGAGCAGCAGCCGCCCCCGGAAGAAGGGAAGAAAGAAGAAGAAGAAGGAAGAAAGAAGAGAAGAAGAGAAGAGTGA

Protein

MVEALSNWPRHMAAIRERLGRAPSARPFGTGFRFLPSSAEEYRAVQAYLSEASARDSTIKWYCYALAEEMPSKVAVRGLPADTDTADVTNALKELGFPARYARCIRSKRGRPGNVFHVALDHLSKDELARLYSVNELMYLPGVTVEGWRPTRGPAQCHRCQAYGHASHNCHRAVRCVRCAAEHTVADCPRPRDGPFSCANCGKDHAAVDRRCPVYRKKARMMGVTVPPPVPPVPPSKRKLMKKARREALENAAPSSVPAIPAIDMEVDINPTTDHIIDDQQPGTSSLPQAQPATSGIQPPLPPRPQRERRSGRQDTQPAGFAAWLLSLWEKLSEELRIIYWNPDGIGSRRSELIRLAQEYDPQVILLGETKLKPRQDFRMPNYFVYRRDELTSNGHPFRGTAALVRRDVVHEELELLTFASTRTVGVRVHVPGAELRIYAAYRPPGPDFVEDDIRRALNHDRHPALVVGDLNAKHVAWGSRIITPPGRRLYEDAERGDYCVVGPNEPTHVPTLARYQPDVLDVCVHKGLQCPLAIEALYDLSTPHLPILVTVGLGLTRVATSPLRPRVDWQSFTGLLADQSLFQDPSTPDEVDTAASRLVDTIRGALDQVTTLVPSGGPRAELPVHLKTLIRRKRALRRLWATSRCPRIKRELNRLEGELATRMRTYRGRGGRRCFTPLARAEVLANSLERQFTPNVSAPSMAAFHREVSEGVIQFLKPESPGVELGDDDLVTPSEVRLLIKLMKRRKAPGEDGIPPLALQNLPPSIVSAMTRLFNSILRVGHFPGTWKLGKIIVLPKPGKDRRKPSSYRPITLLSHVGKLFERLLLRRISPYILLRPEQFGFRSGHSTTLQLTRVLHHLADRRNSGQYTVAVLLDIEKAFDRVWHEGLVHKLRDAGLPHAHVRLLGSYLEGRTFFVAVEGARSSVRPITAGVPQGSVLSPILYALYTNDIPTLEGHLRAWEEDVKLALFADDSAYFSSSPFPSAAIMRMQRLLDILPQWLDRWRVAVNVGKTAALLYGPVRIRVVPKKLSLRGVNVEFRTTVRYLGCDIDRSLSMVAHVNRVIGQARAAMFLLRPVFASGLPTRTKLAIYKTYVRSRLTYAAVAWYHLLSPSQRSRLQAQQSLSLRIIVGAGQYVRNDVIARDLGVESLVEFVTRLARNMYERAENGPHEHLHNIAPLHARPPDGEQQPPPEEGKKEEEEGRKKRRREE

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

A0A2A4JQF8   X1WNI2   X1WZH0   J9LFC9   A0A1Y1NA23   A0A2J7QR37   + More
A0A2J7PBY3   A0A2J7QY69   A0A2J7Q6J2   A0A2J7PU96   A0A224X6Q4   A0A023EYS8   V5GNJ2   A0A224XB44   A0A139W8G9   Q9BPQ0   A0A2S2Q383   Q9XXW0   A0A2J7R7D0   A0A2S2PPK8   A0A2J7R4U3   A0A2J7PDS9   A0A0A9YU04   A0A2J7Q1Y9   Q93137   A0A0A9YJ00   A0A2J7QB68   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7PVX3   A0A1Y1KFR3   A0A139WA11   A0A2S2NGV8   A0A2J7PDM0   A0A224XIB0   A0A2H8TF37   A0A2S2PHL7   A0A2A4K918   A0A2S2N6Q7   A0A0N1PFV1   A0A142LX26   A0A2S2N814   A0A2M4BD83   A0A2S2QEE0   O96546   A0A023F069   A0A2S2R9D4   A0A2H8TKI9   P21328   A0A3N5Z7I3   A0A087UGF5   A0A2S2P6C4   A0A2S2P7B2  

EC Number

2.7.7.49

Pubmed

28004739    25474469    18362917    19820115    10333566    25401762    + More
26354079    25527032    10380107    2463954    3040362    1714378    30086797   

EMBL

NWSH01000895    PCG73652.1    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02034467    + More
ABLF02023911    GEZM01008457    JAV94772.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01017470    PNF24199.1    NEVH01021205    PNF19912.1    GFTR01008279    JAW08147.1    GBBI01004395    JAC14317.1    GALX01005299    JAB63167.1    GFTR01008262    JAW08164.1    KQ973342    KXZ75569.1    AB055391    BAB21761.1    GGMS01002992    MBY72195.1    AB018558    BAA76304.1    NEVH01006736    PNF36716.1    GGMR01018716    MBY31335.1    NEVH01007402    PNF35856.1    NEVH01026154    PNF14491.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01019376    PNF22596.1    U07847    AAA17752.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01016302    PNF25823.1    NEVH01016340    PNF25410.1    NEVH01021925    PNF19341.1    NEVH01020940    PNF20481.1    GEZM01084969    JAV60363.1    KQ971729    KYB24751.1    GGMR01003407    MBY16026.1    NEVH01026386    PNF14434.1    GFTR01008246    JAW08180.1    GFXV01000908    MBW12713.1    GGMR01016296    MBY28915.1    NWSH01000032    PCG80496.1    GGMR01000226    MBY12845.1    KQ459265    KPJ02064.1    KU543673    AMS38352.1    GGMR01000676    MBY13295.1    GGFJ01001822    MBW50963.1    GGMS01006359    MBY75562.1    AF081103    AAC72921.1    GBBI01003810    JAC14902.1    GGMS01017365    MBY86568.1    GFXV01002840    MBW14645.1    M22874    M38643    RPOV01000134    RPJ78669.1    KK119692    KFM76444.1    GGMR01012283    MBY24902.1    GGMR01012676    MBY25295.1   

Proteomes

UP000218220    UP000007819    UP000235965    UP000007266    UP000053268    UP000054359    + More

PRIDE

Q9BPQ0    Q9XXW0    Q93137    P21328   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

A0A2A4JQF8   X1WNI2   X1WZH0   J9LFC9   A0A1Y1NA23   A0A2J7QR37   + More
A0A2J7PBY3   A0A2J7QY69   A0A2J7Q6J2   A0A2J7PU96   A0A224X6Q4   A0A023EYS8   V5GNJ2   A0A224XB44   A0A139W8G9   Q9BPQ0   A0A2S2Q383   Q9XXW0   A0A2J7R7D0   A0A2S2PPK8   A0A2J7R4U3   A0A2J7PDS9   A0A0A9YU04   A0A2J7Q1Y9   Q93137   A0A0A9YJ00   A0A2J7QB68   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7PVX3   A0A1Y1KFR3   A0A139WA11   A0A2S2NGV8   A0A2J7PDM0   A0A224XIB0   A0A2H8TF37   A0A2S2PHL7   A0A2A4K918   A0A2S2N6Q7   A0A0N1PFV1   A0A142LX26   A0A2S2N814   A0A2M4BD83   A0A2S2QEE0   O96546   A0A023F069   A0A2S2R9D4   A0A2H8TKI9   P21328   A0A3N5Z7I3   A0A087UGF5   A0A2S2P6C4   A0A2S2P7B2  

PDB

6AR3     E-value=5.86397e-06,     Score=124

KEGG

101739096    K08220 MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein | (R

GO

GO:0003964   GO:0004519   GO:0008270   GO:0003676  

Length:

1210

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0603500000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00002

outside

1  -  1210

 

 

Pi

389.853

Theta

180.169236

Tajima's D

3.652454

CLR

20.439018

CSRT

0.995900204989751

Interpretation

Uncertain