Gene

KWMTBOMO01203

Pre Gene Modal

BGIBMGA008802

Annotation

neuropeptide_receptor_A14_[Bombyx_mori]

Location

Bomo_Chr3(+):4503185-4527059      View in EpiBrowser

Full name

Neuropeptide CCHamide-2 receptor      

Location in the cell

PlasmaMembrane   Reliability : 4.972

CDS

ATGACTGCCGAAGCTAACTACACGATGTCTGCGGAAAACGACACTGACGAATATATGCCATACGATGAAAGGTTGGAGACATATTTGGTTCCAATATTGTTCGCCGTTATATTCGTTGTCGGGGTGCTTGGGAACGGAACATTGGTGATAGTCTACGCCAGACATAGAGGAATGAGAAACGCTCCTAACACGTATATATTTTCATTAGCGCTAGCGGATCTGCTAGTCATCTTGATATGCGTGCCGTTCGTCTCCATAATCTACACTTTAGAGTCCTGGCCATGGGGAGAGCTTATATGTAGGATCTCTGAATCAGCAAAAGATGTGAGCATTGGTGTATCCGTGTTCACGTTGACAGCCCTATCGGCCGAGAGATATTGTGCGATCGTAAATCCATTCAGGAAACTACAACTTCGCAAACTCCCACTTGTTTGTGCCACATTCATCTGGGGCGCGGCGTTTATCTTTGCCATCCCCGCCGCCATATTCTCCAGTACAGTGACAGTGGAGTTAAAAGACAACGTTACTATCGTATACTGCACGCCGTATCCGAAGGACTGGACTAACTACTCCAAAGGGATGACAATTGCCAAAGCCTTGATATACTACGGTTTGCCGTTGATCGTGATTACGGTTTTCTATTCTCTGATGGCTCGGAGACTACTTGCAAGTACCAGGGAGATGCCAGGAGCTCTTCAAGGCGGTCAAGGCGAGGCTCAGGCTAAAGCTAGAAAGTCGGTAGCTTGCATGGTCCTTATATTTGTTATTGTATTCTTCATCTGCTTTCTGCCTTATCACGCTTTTGAGCTGTGGTATCATTTGTCTCCGACTTCGCTACTCGACTATAACGATTGGACCCACGCGTTGCGCATTATTGGATTCTGTTTGAGTTTCCTGAACTCCTGCGTGAATCCGGTCGCTTTGTACTGCGTCAGCGGCGTCTTCAGGCAGCATTTCAATCGCTACCTGTGCTGTCGCCGAAGCGCCTTACATCCAACTTGCAGCTCGCGTCTATCTAGAACCGCCATATGCGAAACATCGTTCCGGAGCACTCACCGGCATCGGTGCAACAGGAACCCAACAACAGAGAGTGTGGTAATATCGAACTACGATTACGGAAGCACCAACAAGAAGAGCAATATCATAACGAGAAACAACGCCGACGGGGTCACCATACTTACGATTAGGGACTCAAATGTATTCATTTCTGGTGAAATAGACGACAAACGCATCAACAGATAA

Protein

MTAEANYTMSAENDTDEYMPYDERLETYLVPILFAVIFVVGVLGNGTLVIVYARHRGMRNAPNTYIFSLALADLLVILICVPFVSIIYTLESWPWGELICRISESAKDVSIGVSVFTLTALSAERYCAIVNPFRKLQLRKLPLVCATFIWGAAFIFAIPAAIFSSTVTVELKDNVTIVYCTPYPKDWTNYSKGMTIAKALIYYGLPLIVITVFYSLMARRLLASTREMPGALQGGQGEAQAKARKSVACMVLIFVIVFFICFLPYHAFELWYHLSPTSLLDYNDWTHALRIIGFCLSFLNSCVNPVALYCVSGVFRQHFNRYLCCRRSALHPTCSSRLSRTAICETSFRSTHRHRCNRNPTTESVVISNYDYGSTNKKSNIITRNNADGVTILTIRDSNVFISGEIDDKRINR

Description

Receptor for the neuropeptide CCHamide-2.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Keywords

Alternative splicing   Cell membrane   Complete proteome   Disulfide bond   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Neuropeptide CCHamide-2 receptor
splice variant  In isoform B.

Uniprot

B3XXM7   A0A0S1YDF3   A0A194QHC7   A0A0N0PD66   A0A212F7B8   A0A182F811   + More
A0A1W4XJZ6   A0A182VDW4   A0A182P8Z5   A0A182KXP6   A0A182WVM5   D6WV75   V9I0H3   A0A182QHG4   A0A182VXK3   N6TPJ0   U4U619   A0A2J7Q927   A0A0K8V8Z3   A0A0S1YD78   A0A2S2PUK5   Q7PQF5   A0A2A4JRS4   A0A2S2QMN0   A0A0A1XNX2   A0A0A1X6K2   A0A034W4Z0   A0A182RBG5   J9JWL6   A0A2R7W5T6   A0A087ZMW0   B4MR49   K7ISZ6   U3U7M5   B4J4A3   B3XXM8   A0A0M4EFN8   A0A067R841   A0A1W4VIS6   A0A023F665   B4KLZ3   B4LIK1   B3MJ73   A0A1I8Q7Y9   A0A3L8DX22   A0A026WQH4   A0A0J9R678   B4II33   Q4V622   A0A2U9PG12   Q4V622-2   Q28WQ5   B4QCR2   B4NYV4   A0A2J7Q987   B4H738   E2AWG8   B3N3G1   A0A232EZQ2   A0A2U9PG18   A0A1S3DS75   T1H9A6   A0A0L7R6T4   A0A2P8YVS0   A0A3B0J1R9   A0A1S3D5Z2   A0A0M8ZTM5   A0A154PF30   A0A1B0G718   A0A1B0AGA2   A0A1J1IU74   A0A336KUH4   A0A158NYP9   A0A2A3ECB8   B4LNA0   A0A1A9ZYI9   A0A139WD04   A0A1A9V9R2   A0A1B0G0X0   A0A182YIB7   A0A182VM06   A0A182MXX0   A0A182MPE2   A0A182H4I9   A0A182QV95   Q16M90   A0A1A9W0W8   E2BPQ0   U3U959   A0A182J0B4   T1HUP6   B4KN01   A0A1B6ICU8   A0A182FTD1   A0A1B0BUC5   B4MIS7   B3MIF2  

Pubmed

18725956    26354079    22118469    20966253    18362917    19820115    + More
23537049    12364791    14747013    17210077    25830018    25348373    17994087    20075255    23932938    24845553    25474469    18057021    30249741    24508170    22936249    21110953    10731132    12537572    23293632    24098432    26020940    26394035    15632085    17550304    20798317    28648823    29403074    21347285    25244985    26483478    17510324   

EMBL

AB330435    BAG68413.1    KT031012    ALM88310.1    KQ458860    KPJ04824.1    + More
KQ460366    KPJ15631.1    AGBW02009890    OWR49633.1    KQ971363    EFA09272.1    HQ703464    ADZ15314.1    AXCN02000284    APGK01056811    APGK01056812    APGK01056813    KB741277    ENN71140.1    KB631786    ERL86066.1    NEVH01016943    PNF25073.1    GDHF01016967    JAI35347.1    KT031013    ALM88311.1    GGMR01020385    MBY33004.1    AAAB01008888    EAA08917.3    NWSH01000696    PCG74737.1    GGMS01009597    MBY78800.1    GBXI01001253    JAD13039.1    GBXI01007348    JAD06944.1    GAKP01009168    JAC49784.1    ABLF02022539    ABLF02022541    ABLF02022542    ABLF02022543    ABLF02034748    ABLF02053397    KK854364    PTY15097.1    CH963849    EDW74588.1    AAZX01009174    AB817298    BAO01065.1    CH916367    EDW00583.1    AB330436    BAG68414.1    CP012524    ALC41060.1    KK852871    KDR14578.1    GBBI01002008    JAC16704.1    CH933808    EDW10782.2    CH940648    EDW60371.2    CH902619    EDV38167.2    KPU77300.1    KPU77301.1    QOIP01000003    RLU25020.1    KK107151    EZA57359.1    CM002911    KMY91692.1    CH480841    EDW49559.1    AY282787    AE013599    BT022484    AAQ19611.1    AAY54900.1    MG550204    AWT50638.1    CM000071    EAL26612.1    CM000362    EDX05851.1    CM000157    EDW89805.1    PNF25139.1    CH479216    EDW33571.1    GL443287    EFN62213.1    CH954177    EDV59843.1    NNAY01001485    OXU23809.1    MG550203    AWT50637.1    ACPB03005200    KQ414646    KOC66558.1    PYGN01000333    PSN48337.1    OUUW01000001    SPP72803.1    KQ435896    KOX69289.1    KQ434890    KZC10422.1    CCAG010003762    CVRI01000059    CRL03743.1    UFQS01000834    UFQT01000834    SSX07155.1    SSX27498.1    ADTU01004175    ADTU01004176    KZ288302    PBC28826.1    EDW61052.1    KYB25711.1    CCAG010020384    AXCM01013418    AXCM01013419    AXCM01013420    JXUM01109685    JXUM01109686    JXUM01109687    KQ565344    KXJ71074.1    AXCN02002114    CH477872    EAT35449.1    GL449657    EFN82325.1    AB817297    BAO01064.1    ACPB03005213    EDW09923.1    KRG04984.1    GECU01022948    JAS84758.1    JXJN01020601    CH963719    EDW72016.1    EDV37000.1   

Proteomes

UP000053268    UP000053240    UP000007151    UP000069272    UP000192223    UP000075903    + More
UP000075885    UP000075882    UP000076407    UP000007266    UP000075886    UP000075920    UP000019118    UP000030742    UP000235965    UP000007062    UP000218220    UP000075900    UP000007819    UP000005203    UP000007798    UP000002358    UP000001070    UP000092553    UP000027135    UP000192221    UP000009192    UP000008792    UP000007801    UP000095300    UP000279307    UP000053097    UP000001292    UP000000803    UP000001819    UP000000304    UP000002282    UP000008744    UP000000311    UP000008711    UP000215335    UP000079169    UP000015103    UP000053825    UP000245037    UP000268350    UP000053105    UP000076502    UP000092444    UP000092445    UP000183832    UP000005205    UP000242457    UP000078200    UP000076408    UP000075884    UP000075883    UP000069940    UP000249989    UP000008820    UP000091820    UP000008237    UP000075880    UP000092460   

PRIDE

B3XXM7    B3XXM8    Q4V622   

Pfam

PF00001   7tm_1

Interpro

IPR017452   GPCR_Rhodpsn_7TM        + More
IPR000276   GPCR_Rhodpsn       
IPR001556   Bombsn_rcpt-like       
IPR000611   NPY_rcpt       

ProteinModelPortal

B3XXM7   A0A0S1YDF3   A0A194QHC7   A0A0N0PD66   A0A212F7B8   A0A182F811   + More
A0A1W4XJZ6   A0A182VDW4   A0A182P8Z5   A0A182KXP6   A0A182WVM5   D6WV75   V9I0H3   A0A182QHG4   A0A182VXK3   N6TPJ0   U4U619   A0A2J7Q927   A0A0K8V8Z3   A0A0S1YD78   A0A2S2PUK5   Q7PQF5   A0A2A4JRS4   A0A2S2QMN0   A0A0A1XNX2   A0A0A1X6K2   A0A034W4Z0   A0A182RBG5   J9JWL6   A0A2R7W5T6   A0A087ZMW0   B4MR49   K7ISZ6   U3U7M5   B4J4A3   B3XXM8   A0A0M4EFN8   A0A067R841   A0A1W4VIS6   A0A023F665   B4KLZ3   B4LIK1   B3MJ73   A0A1I8Q7Y9   A0A3L8DX22   A0A026WQH4   A0A0J9R678   B4II33   Q4V622   A0A2U9PG12   Q4V622-2   Q28WQ5   B4QCR2   B4NYV4   A0A2J7Q987   B4H738   E2AWG8   B3N3G1   A0A232EZQ2   A0A2U9PG18   A0A1S3DS75   T1H9A6   A0A0L7R6T4   A0A2P8YVS0   A0A3B0J1R9   A0A1S3D5Z2   A0A0M8ZTM5   A0A154PF30   A0A1B0G718   A0A1B0AGA2   A0A1J1IU74   A0A336KUH4   A0A158NYP9   A0A2A3ECB8   B4LNA0   A0A1A9ZYI9   A0A139WD04   A0A1A9V9R2   A0A1B0G0X0   A0A182YIB7   A0A182VM06   A0A182MXX0   A0A182MPE2   A0A182H4I9   A0A182QV95   Q16M90   A0A1A9W0W8   E2BPQ0   U3U959   A0A182J0B4   T1HUP6   B4KN01   A0A1B6ICU8   A0A182FTD1   A0A1B0BUC5   B4MIS7   B3MIF2  

PDB

6B73     E-value=1.92466e-24,     Score=279

KEGG

100174918    K04170 bombesin receptor subtype-3 | (RefSeq) NGR-A14, BNGR-A14; neuropeptide receptor A14

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0008528   GO:0007218   GO:0016021   GO:0004930   GO:0007186   GO:0005887   GO:0008188   GO:0005886   GO:0008261   GO:0004983   GO:0006000   GO:0004553   GO:0005634   GO:0006334   GO:0003779  

Subcellular location

Cell membrane  

Length:

413

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

155.08414

Exp number, first 60 AAs:

23.15581

Total prob of N-in:

0.05510

POSSIBLE N-term signal

sequence

outside

1  -  29

TMhelix

30  -  52

inside

53  -  64

TMhelix

65  -  87

outside

88  -  108

TMhelix

109  -  128

inside

129  -  140

TMhelix

141  -  163

outside

164  -  193

TMhelix

194  -  216

inside

217  -  245

TMhelix

246  -  268

outside

269  -  287

TMhelix

288  -  310

inside

311  -  413

 

 

Pi

17.472477

Theta

20.851642

Tajima's D

-1.215839

CLR

210.297713

CSRT

0.0993950302484876

Interpretation

Uncertain